Human immunodeficiency virus accelerates brain aging and disrupts the trajectory of glymphatic clearance in aging brain by Benedictor Alexander Nguchu, Benedictor Alexander Nguchu, Jing Zhao, Yu Lu, Yifei Han, Han Jin, Xiaoxiao Wang, Hongjun Li, Peter Shaw

“…We further evaluated the association between accelerated brain aging trajectories and cognitive performance to explain impairments observed in motor and executive functions in people living with HIV. ResultsOur results showed that subjects with HIV had increased brain-PAD in several brain structures compared to those who were HIV-negative, suggesting underlying neuropathology associated with HIV. …”
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Evaluation of psychotropic effects of a novel chromone-containing allylmorpholine derivative in BALB/c mice by M. M. Puchik, D. D. Shitc, Yu. I. Sysoev, N. M. Chernov, I. A. Titovich, S. V. Okovityi

“…The present study investigated the effects of 33a on anxiety behavior, cognitive functions, and grip strength of BALB/c mice after acute and chronic administration.Materials and methods. …”
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Alginate-hydroxyapatite scaffolds: A comprehensive characterization study by Saanvi Gupta, Suganya Panneer Selvam, Ramya Ramadoss, Sandhya Sundar

“…With excellent degradation, hemocompatibility, and ability to support cellular functions, these scaffolds hold significant potential for clinical applications, with further optimization paving the way for broader medical adoption.…”
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Methylation of p53-responsive oncosuppressive microRNA genes in hemoblastosis by E. N. Voropaeva, T. I. Pospelova, O. V. Berezina, M. I. Churkina, A. A. Gurazheva, V. N. Maksimov

“…The review examines the molecular and genetic characteristics of oncosuppressive micrornas functioning in normal hematopoiesis, the violation of expression of which is shown in the development of hemoblastoses, namely: miR-34a, miR-34b/c, miR-145, miR-143 and miR-203. …”
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Treatment Modalities for Aromatase Inhibitor-Associated Musculoskeletal Syndrome (AIMSS): A Scoping Review of Prospective Treatment Studies by Bobo JA, Lubrano B, Rosario-Concepcion R, Cuartas-Abril A, Advani P, Chumsri S, Bruce BK

“…Intervention effects on a wide range of outcomes were studied, including pain or stiffness (70 reports), functioning/disability (34 reports), quality of life (37 reports), mental health symptoms (25 reports), pain self-efficacy (4 reports), and AI persistence (3 reports). …”
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Central nervous system and systemic inflammatory networks associated with acute neurological outcomes in COVID-19 by Nicole Lardini Freitas, João Victor Carvalho Deus, Karen Sampaio, Yago Côrtes Pinheiro Gomes, Rafael Carvalho Torres, Carlos Otávio Brandão, Cristiane Nascimento Soares, Marcus Tulius Teixeira Silva, Otávio Melo Espíndola

“…Individuals with non-inflammatory, non-infectious neurological conditions (n = 9) were included as negative controls. Paired CSF and serum samples were assessed for 56 biomarkers. …”
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GPD1L as a potential biomarker associated with Treg cell infiltration and lipid metabolism in clear cell renal cell carcinoma by Ming Yang, Dejiang Pang, Chuhui Gong, Kangping Song, Hongbo Ma, Yu Yang, Shujin Guo, Liqiong Wang

“…Then the single cell sequencing dataset (GEO) was further analyzed and verified, and the functional phenotype of GPD1L in ccRCC was explored by functional experiments. …”
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Synthesis, toxicity and antioxidant activity of phenolic benzimidazole derivatives: In vitro and in silico studies by Mithun Rudrapal, Mohammad Mojammil, Azmal Farooque, Masoom Ansari, André M. de Oliveira, Johra Khan

“…Density functional theory (DFT) calculations provided insight into the antioxidant mechanisms, suggesting that 3b predominantly follows a hydrogen atom transfer (HAT) mechanism, whereas 3a exhibits a stronger electron-donating ability. …”
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Heterogeneity of T cells regulates tumor immunity mediated by Helicobacter pylori infection in gastric cancer by Zhisheng Wu, Xinya Wang, Shujing Shi, Deyuan Kong, Chuanli Ren, Lijun Bian, Yuanliang Gu, Fangmei An, Qiang Zhan, Caiwang Yan, Chupeng Hu, Yun Chen, Runqiu Jiang, Jinfei Chen

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A DNA Vaccine Against Proadrenomedullin N-Terminal 20 Peptide (PAMP) Reduces Angiogenesis and Increases Lymphocyte and Macrophage Infiltration but Has No Effect on Tumor Burden in... by Tom Kalathil Raju, Srdan Tadic, Pablo Garrido, Laura Ochoa-Callejero, Judit Narro-Íñiguez, Josune García-Sanmartín, Alfredo Martínez

“…<b>Conclusions:</b> Although the vaccine was not effective in reducing tumor growth, new proliferative and immune functions have been described for PAMP. These new functions include induction of melanoma proliferation and modulation of lymphocyte and macrophage tumor infiltration dynamics.…”
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To the selection of shock absorber elements of the artificial foot by G. N. Burov, L. M. Smirnova, V. A. Bolshakov, V. M. Yankovsky, O. L. Belyanin

“…At the same time, each of them turned out to be more functional than the commercially manufactured foot chosen for the study. …”
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Dyslipidemia in kidney receiver by S. M. Martirosyan, E. D. Kosmacheva

“…Level of the general cholesterol was a significant independent predictor for survival and functioning of the renal allotransplantat in 3 years after transplantation.Conclusion. …”
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Minimally invasive treatment of grade I and II gluteal muscle contracture using a self-made special cutter combined with a specialized compression hemostasis device by Yingguo Yang, Zixuan Peng, Linlin Shi, Ye Wang, Yuan Wang, Bing Ge, Dongcheng Zhu, Zhiyuan Ye

“…Additionally, it causes less trauma, simplifies the operation, reduces intraoperative and postoperative bleeding, allows for early functional exercise, and promotes rapid functional recovery. …”
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NCBP2 predicts the prognosis and the immunotherapy response of cancers: a pan-cancer analysis by Shichao Li, Yulan Wang, Xi Yang, Miao Li, Guoxiang Li, Qiangqiang Song, Junyu Liu

“…Nevertheless, the precise biological functions and clinical implications of CBC in cancer remain ambiguous, necessitating further investigation for clarification. …”
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Microbial biomass – not diversity – drives soil carbon and nitrogen mineralization in Spanish holm oak ecosystems by Elisa Bruni, Jorge Curiel Yuste, Lorenzo Menichetti, Omar Flores, Daniela Guasconi, Bertrand Guenet, Ana-Maria Hereș, Aleksi Lehtonen, Raisa Mäkipää, Marleen Pallandt, Leticia Pérez-Izquierdo, Etienne Richy, Mathieu Santonja, Boris Tupek, Stefano Manzoni

“…Soil microbial communities drive essential ecosystem functions, catalyzing biogeochemical cycles and contributing to climate regulation. …”
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Dietary macronutrients modulate the proteome of brown adipose tissue in males and their female offspring by Erin L. Macartney, Alistair M. Senior, Angela J. Crean, Lewin Small, Lou Ruffino, Tamara J. Pulpitel, Marcelo A. Nobrega, Romain Barrès, Stephen J. Simpson

“…However, the effects of macronutrients and paternal effects on BAT function have yet to be characterized. We investigated the effects of macronutrient composition on the BAT proteome in male mice and offspring. …”
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Dysregulated macrophage immunity in Helicobacter pylori infection: unveiling mechanistic insights and therapeutic implications by Miao Xiang, Miao Xiang, Panpan Li, Panpan Li, Xiaofei Yue, Linlin Liu, Linlin Liu, Linjing Wang, Nengjin Sun, Nengjin Sun, Kaile Wang, Kaile Wang, Yuying Zhang, Hongyan Wang, Hongyan Wang

“…Helicobacter pylori (H. pylori) is a microaerophilic, gram-negative spirochete that primarily colonizes the human gastric mucosa. …”
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NXF1 suppresses progression of endometrial cancer by interacting with the SRSF3 to regulate SP4 splicing by Nan Meng, Lingjun Li, Xueqin Yang, Hui Tang, Jizhong Wang, Songbai Zhang, Zongbao Xia, Jia Yao, Qi Zhang, Changrong Hu, Chunjie Su, Rui Duan

“…Mouse models and molecular biology assays were used to elucidate NXF1’s function and mechanisms in vitro and in vivo. Results showed NXF1 expression was negatively correlated with histological grade and poor patient prognosis. …”
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Clinical and brain volumetric correlates of decreased DTI-ALPS, suggestive of local glymphatic dysfunction, in iRBD by Ignacio Roura, Jèssica Pardo, Cristina Martín-Barceló, Carles Falcon, Javier Oltra, Anna Campabadal, Nuria Bargalló, Mònica Serradell, Gerard Mayà, Angelica Montini, Claustre Pont-Sunyer, Carles Gaig, Mariateresa Buongiorno, Carme Junqué, Alex Iranzo, Bàrbara Segura

“…The DTI-ALPS positively correlated with cognitive performance, olfactory function and amygdalar, hippocampal, brainstem and diencephalic volumes, and negatively with age in iRBD. …”
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Sarcopenia in Rheumatic Diseases: A Hidden Issue of Concern by Eleni C. Pardali, Markos Klonizakis, Dimitrios G. Goulis, Sousana K. Papadopoulou, Christos Cholevas, Constantinos Giaginis, Christina Tsigalou, Dimitrios P. Bogdanos, Maria G. Grammatikopoulou

“…Sarcopenia is characterized by a loss of muscle mass and function, with significant implications for the physical performance of the affected people. …”
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