Prophylactic effect of nano vitamin D3 against fatty degeneration caused by calcium-deficient diet in parotid salivary gland: a histological and ultrastructural study by Maha Mohamed Montaser, Dina M. Mahdy, Sara A. Hamza

“…Abstract Background Poor dietary habits, such as a calcium-deficient diet, negatively impact oral health by impairing salivary gland function due to hypocalcemia. …”
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ESR1 is co-expressed with closely adjacent uncharacterised genes spanning a breast cancer susceptibility locus at 6q25.1. by Anita K Dunbier, Helen Anderson, Zara Ghazoui, Elena Lopez-Knowles, Sunil Pancholi, Ricardo Ribas, Suzanne Drury, Kally Sidhu, Alexandra Leary, Lesley-Ann Martin, Mitch Dowsett

“…The co-expression and function of these genes may be important influences on the recently identified relationship between SNPs in this region and breast cancer risk.…”
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Detection of human activities using multi-layer convolutional neural network by Essam Abdellatef, Rasha M. Al-Makhlasawy, Wafaa A. Shalaby

“…Each block integrates a convolutional layer, a ReLU activation function, and a batch normalization layer. The outputs from specific blocks “ConvBlk_3 and ConvBlk_4,” “ConvBlk_6 and ConvBlk_7,” and “ConvBlk_9 and ConvBlk_10” are fused using a depth concatenation approach. …”
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Relationship between red blood cell distribution width with non-invasive hemodynamic monitoring and body composition in peritoneal dialysis patients by YAO Yun-jiao, WU Yong-gui

“…Objective To investigate the relationship between the red blood cell distribution width（RDW） with non-invasive hemodynamic monitoring and body composition in peritoneal dialysis（PD） patients,and its applied value in PD patients.Methods Forty-four hospitalized PD patients were retrospectively reviewed,and 30 cases of healthy people served as a control group.The clinical characteristics and parameters such as RDW,brain natriuretic peptide（BNP）,N-terminal brain natriuretic peptide（NT-proBNP）,non-invasive hemodynamics and body composition were collected.The differences between two groups and the relationship between RDW and other parameters were analyzed.Results The RDW,BNP,and NT-proBNP in PD group were significantly higher than in the control group with the difference being statistically significant（P<0.01）.ECW/TBW was significantly higher,and body fat mass,body mass index,percent body fat,visceral fat area and body-hip ratio were significantly lower in PD group than those in the control group（P<0.05）.RDW in PD group was positively correlated with BNP and NT-proBNP（r₁ = 0.417,r₂ = 0.396;P<0.01）,and BNP was positively correlated with NT-proBNP（r = 0.891,P<0.01）.RDW was positively correlated with HR and STR（r₁ = 0.343,r₂ = 0.364,P<0.05）,and negatively with CI,SV,SI,EF,VI（r₁ =-0.277,r₂ =-0.399,r₃ =-0.437,r₄ =-0.335,r₅ =-0.338,P<0.05）.In PD group RDW was positively correlated with ECW/TBW（n = 0.300,P<0.05）.Multivariate linear regression method showed that RDW was associated with ECW/TBW（t = 2.03,P<0.05）.Conclusions RDW can be used as a predictor of poor prognosis in PD patients,and NT-proBNP can be used to assess the cardiac function in dialysis patients instead of BNP.…”
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Regulation of the Inflammatory Response, Proliferation, Migration, and Epithelial-Mesenchymal Transition of Human Lens Epithelial Cells by the lncRNA-MALAT1/miR-26a-5p/TET1 Signali... by Yaru Hu, Xue Han, Yue Chen, Jinbiao Cai, Juan Li, Yuchen Fan, Jianfeng Wang, Shanglun Xie

“…Furthermore, MALAT1 negatively regulated the expression of miR-26a-5p and then promoted TET1 expression. …”
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A systematic literature review of the impact and measurement of mobility impairment in rare bone diseases by Inês Alves, Ingunn Westerheim, Edward C. Hsiao, Jaymin Upadhyay, Luca Sangiorgi, Alexander Artyomenko, Kim Croskery, Juliet Johns, Emma Warnants, Gabor Barton

“…Mobility impairments, commonly joint function/gait disturbances, negatively impacted daily activities ( n  = 47 cohorts; frequently walking (27/47; 57.4%)) and QoL ( n  = 36 cohorts; commonly pain (30/36; 83.3%; Objective 1). …”
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The Role of a Smartphone Application in Monitoring the Risk of Hearing Loss Associated with Personal Listening Devices in Young Adults by Deniz Tuz, Selin Sariçamlik, Ceren Bodur, Gülce Kirazli, Pelin Piştav Akmeşe

“…Data from the iOS “Health” application indicated that some individuals were at risk of hearing loss, suggesting the need to modify their listening habits to prevent long-term decline in hearing function.…”
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Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer. by Anju Singh, Vikas Misra, Rajesh K Thimmulappa, Hannah Lee, Stephen Ames, Mohammad O Hoque, James G Herman, Stephen B Baylin, David Sidransky, Edward Gabrielson, Malcolm V Brock, Shyam Biswal

“…Kelch-like ECH-associated protein 1 (KEAP1) negatively regulates NRF2 activity by targeting it to proteasomal degradation. …”
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The quality of life analysis of knee prosthesis with complete microprocessor control in trans-femoral amputees by Yavuz Saglam, Baris Gulenc, Fevzi Birisik, Ali Ersen, Ebru Yilmaz Yalcinkaya, Onder Yazicioglu

“…Conventional prostheses usage time was positively correlated with physical function (PF) scores (r = 0.322, p = 0.010). Microprocessor prosthesis usage time was negatively correlated with role limitations due to emotional problem (RE) scores (r = −0,313, p = 0.009). …”
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TaER Expression Is Associated with Transpiration Efficiency Traits and Yield in Bread Wheat. by Jiacheng Zheng, Zhiyuan Yang, Pippa J Madgwick, Elizabete Carmo-Silva, Martin A J Parry, Yin-Gang Hu

“…These combined results suggested that TaER involved in development of transpiration efficiency -related traits and yield in bread wheat, implying a function for TaER in regulating leaf development of bread wheat and contributing to expression of these traits. …”
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Unlocking the Neuroprotective Effect of Quercetin Against Cadmium-Induced Hippocampal Damage in Rats: PPARγ Activation as a Key Mechanism by Doha M. Al-Nouri

“…At the end of the experiment, behavioral memory tests, hippocampal histology, markers of cholinergic function, neuroplasticity, oxidative stress, inflammation, and apoptosis, as well as transcription levels of some genes were carried out. …”
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miR-29c-3p downregulation accelerates spinal cord injury progression by targeting BRD4 by Dawei Wang, Xiaona Wang, Yingshuang Wu, Sina Qi, Haifeng Hu, Jifei Guo, Yi Luo

“…Studies have highlighted the multifaceted regulatory roles of miR-29c-3p in neuronal development and function; however, its role in SCI remains unclear. …”
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Metabolism-related hepatokines change in biliary atresia: ANGPTL6 as a potential biomarker by Daiqiong Fang, Shuqi Hu, Jinfa Tou, Fengqin Dong, Shiqiao Peng

“…Blood samples were obtained for measuring liver function and hepatokine levels. Linear correlations between these changes in hepatokines and bilirubin/bile acid were subsequently examined to explore the hepatokines that may reflect the illness severity. …”
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Epidemiological Informing of the Population in Cities: Models and Their Application by Vasiliy Osipov, Marina Osipova, Sergey Kuleshov, Alexandra Zaytseva, Aleksey Aksenov

“…The method is characterized by a new objective function that links economic efficiency with the state of health of the population in an epidemic. …”
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Exploring the therapeutic mechanisms of heart failure with Chinese herbal medicine: a focus on miRNA-mediated regulation by Yang Wang, Junyu Lai, Zhengtao Chen, Liqiang Sun, Yirong Ma, Jianguang Wu

“…Heart failure (HF) is a clinical condition caused by abnormalities in the heart’s structure or function, primarily manifested as diminished ability of the heart to pump blood, which leads to compensatory activation of neurohormones and increased left ventricular filling pressure. …”
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Phosphorus Utilization Efficiency Among Corn Era Hybrids Released over Seventy-Five Years by Kwame Ampong, Chad J. Penn, James Camberato, Daniel Quinn, Mark Williams

“…Grain P content was negatively correlated with stem P content (R² = 0.89). …”
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miR-455 inhibits neuronal cell death by targeting TRAF3 in cerebral ischemic stroke by Yao ST, Tang B, Li G, Fan RM, Cao F

“…Furthermore, TRAF3 was proved&amp;nbsp;to be a direct target of miR-455, and miR-455 could negatively suppress TRAF3 expression. Biological function analysis showed that TRAF3 silencing displayed the neuroprotective effect in ischemic stroke and could enhance miR-455-induced positive impact on ischemic injury both in vitro and in vivo. …”
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Adverse events that occurred in patients with rheumatoid arthritis during long-term follow-up by I. S. Dydykina, P. O. Postnikova, P. S. Kovalenko, S. I. Glukhova, A. M. Lila

“…Comorbid diseases and adverse events that occur in patients with rheumatoid arthritis (RA) negatively affect the outcomes of RA (radiological progression, joint function, the occurrence of low-energy fractures, thrombotic events, etc.).   …”
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Assessment of Health-Related Quality of Life in children with bronchial asthma and their caregivers at a teaching institution: A cross-sectional study by U.S Nitya, Vaishnavi Sreenivasan, Aparna Anand Gulvadi, Riya Lukose

“…Scores related to individual domains of symptoms, activity limitation, and emotional function were calculated. Results: Well-controlled asthma was noted in 63.3%, partly controlled in 21.7%, and uncontrolled in 15%. …”
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Redox metabolic disruptions in the honey bee brain following acute exposure to the pyrethroid deltamethrin by Máté Mackei, Fanni Huber, Barnabás Oláh, Zsuzsanna Neogrády, Gábor Mátis

“…The activities of the monitored enzymes, such as glucose-6-phosphate dehydrogenase (G6PDH), superoxide dismutase (SOD), and xanthine oxidase (XO), were significantly decreased, highlighting the altered function of the enzymatic antioxidant defense system. …”
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