Impact of Carotid Endarterectomy on Choroidal Thickness and Volume in Enhanced Depth Optical Coherence Tomography Imaging by Elżbieta Krytkowska, Monika Masiuk, Miłosz P. Kawa, Aleksandra Grabowicz, Paweł Rynio, Arkadiusz Kazimierczak, Krzysztof Safranow, Piotr Gutowski, Anna Machalińska

“…The choroid is a predominantly vascular tissue; thus, systemic and local vascular alterations may influence its morphology and function. The aim of the current study was to analyse changes in choroidal thickness and volume in patients with significant internal carotid artery stenosis (ICAS) before and after unilateral CEA. …”
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Gender differences in trunk appearance perception and health-related quality of life (HRQoL) in the patients with moderate adolescent idiopathic scoliosis (AIS) undergoing orthotic... by JoJo Yiying Zou, Tung Li, Man Sang Wong

“…In females, increasing age was negatively correlated with TAPS scores, whereas in males, it showed a positive correlation. …”
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Reprogramming of H3K27me3 is critical for acquisition of pluripotency from cultured Arabidopsis tissues. by Chongsheng He, Xiaofan Chen, Hai Huang, Lin Xu

“…Changes in H3K27me3 levels were negatively correlated with expression levels of the corresponding genes. …”
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The study of miR-130a expression and its mechanism of action in peripheral blood endothelial progenitor cells (EPCs) in type 2 diabetes mellitus (T2DM) by Yawei Cai, Yao Zhu, Ning Xu, Tongen Chen

“…Tube formation assay, cell adhesion assay and Transwell assay were performed to evaluate effect of TGF-β1/miR-130a/IL-18 axis on the EPCs functions. Accordingly, in EPCs treated with TGF-β1, we found that the levels of miR-130a were reduced, and its expressions were also negatively correlated with the expressions of IL-18 in the EPC groups. …”
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B1 SOX coordinate cell specification with patterning and morphogenesis in the early zebrafish embryo. by Yuichi Okuda, Eri Ogura, Hisato Kondoh, Yusuke Kamachi

“…However, their regulatory functions in stages from the blastula to early neurula remain largely unknown, primarily because loss-of-function studies have not been informative to date. …”
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Effects of Climate Change on the Immune System: A Narrative Review by Luisa Imberti, Giorgio Tiecco, Jacopo Logiudice, Francesco Castelli, Eugenia Quiros‐Roldan

“…Temperature fluctuations have been shown to influence various aspects of the adaptive immune response, including immune cell mobilization, antigen processing and presentation, lymphocyte trafficking and activation, and the functionality of B and T cells. Notably, some research suggests that heat stress negatively impacts B lymphocyte differentiation, replication, and proportion, resulting in decreased immunoglobulin and cytokine production, and contributing to immunosuppression. …”
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LABORATORY FINDINGS OF CHILDREN ASSESSED IN RELATION TO COGNITIVE STATE BY THE HEALTH COMMITTEE OF A SECOND LEVEL STATE HOSPITAL by Fatma Gül Demirkan, Şeyma Karatekin

“…Objective: The aim of this study is to investigate the relation between anemia, vitamin deficiency, thyroid dysfunction, and the cognitive status of patients admitted to the medical board due to symptoms of cognitive retardation, a condition that is common in childhood and affects school success negatively. Materials and Methods: In this study, between January 2016- June 2018, serum vitamin B12, ferritin, hemogram and thyroid function tests of 71 pediatric patients, who were found to have had cognitive deficiencies and were admitted to the secondary level state hospital to obtain a medical committee report, were assessed retrospectively. …”
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The relationship of body image with sexual dysfunction and dyadic adjustment in individuals diagnosed with bipolar disorder in Türkiye by Emine Reyhan Yazar, Filiz İzci

“…In this context, it was specifically aimed to determine the link between these factors and quality of life (QoL) in individuals with BD based on the effects of BI on sexual function and marital adjustment.MethodsThis study was conducted in a psychiatric hospital in Turkiye. …”
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Evaluation of frizzled class receptor 3 and miR-378 expression levels in cumulus cells of polycystic ovary syndrome women: A case-control study by Amir Mohammad Bagheri, Kimia Monshizadeh, Fatemeh Anbari, Nasrin Ghasemi, Mohammadreza Dehghani

“…Currently, various aspects of microRNA function remain unknown. MiR-378 may exert its regulatory role by directly targeting the FZD3 gene or by targeting other genes and mediators that interact with FZD3 or the protein it encodes. …”
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The association between basilar artery wall thickness and posterior circulation ischemic stroke: insights from high-resolution vascular wall imaging in subclinical atherosclerosis by Zhen Zhang, Lirong Yi, Jie Zhou, Xiaojing He, Mingjing Yuan, Bo Xiang

“…Basilar atherosclerosis is a major cause of posterior circulation ischemic stroke and it can affect neurological function negatively. Little is known about subclinical atherosclerotic changes before plaque formation. …”
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Association Between Dietary Taste Preferences and Primary Ovarian Insufficiency: A Mendelian Randomization Study by Xu S, Zhou Y, Wang L, Zhang Y

“…The analyses were visualized by plotting scatterplots, funnel plots, and leave-one-out plots.Results: IVW analysis showed that preference for sweet food (p=0.034), preference for cake (p=0.040), preference for white wine (p=0.048) was positively associated with the risk of developing POI, preference for bitter food (p=0.048), preference for Mackerel (p=0.031), preference for Gherkins (p=0.024), preference for Cream (p= 0.009) and preference for Soya milk (p=0.042) were negatively associated with the risk of developing POI, while there was no significant association between preference for salty food (p=0.350) and preference for spicy food (p=0.827) and POI.Conclusion: This study suggests that food preference is a heritable trait, that food preference is the primary reason people choose their food intake, and that alterations in taste-related receptor genes may affect ovarian function. …”
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Severity and Prognosis of Vascular Dementia in Patients with Acute Cerebral Infarction Combined with H-Type Hypertension and Its Correlation with Uric Acid Levels by Hong Y, Feng M

“…Uric acid levels were compared between groups. Based on cognitive function scores, patients were further classified into mild, moderate, and severe dementia subgroups, and differences in uric acid and homocysteine levels were analyzed. …”
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Analysis of Air Quality Changes and Influencing Factors in Changchun during the COVID-19 Pandemic in 2020 by Hanbo Gao, Ju Wang, Tongnan Li, Chunsheng Fang

“…Temperature and O3 were positively correlated before the lockdown and during Level I and weakly negatively correlated during Level II and Level III. …”
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Influence of Migratory Strategy, Group Size, and Environmental Conditions on the Movements of Caribou in Eastern Alaska by Kyle Joly

“…The connection between group size and movement rates may be a function of competition or a small-scale example of the larger-scale phenomenon of range expansion of large herds. …”
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The association between the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and lymphocyte-to-monocyte ratio and delirium in ischemic stroke patients by Pangbo Wang, Pangbo Wang, Jing Huang, Liwei Xu, Rong Hu

“…In the MR analysis, only the PLR was negatively associated with the risk of delirium.ConclusionThe observational studies found significant associations between the NLR, PLR, and LMR and delirium. …”
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Association of non-selective β blockers with the development of renal dysfunction in liver cirrhosis: a systematic review and meta-analysis by Xiangbo Xu, Fangbo Gao, Ting Wang, Zuyao Yang, Qingchun Zhao, Xingshun Qi

“…Background & Aims Non-selective β blockers (NSBBs) may negatively influence renal function through decreasing heart rate and cardiac output. …”
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The association between adiposity, mental well-being, and quality of life in extreme obesity. by Alison C Jagielski, Adrian Brown, Marzieh Hosseini-Araghi, G Neil Thomas, Shahrad Taheri

“…Increasing adiposity was significantly negatively associated with quality of life, with an increase of 1 BMI unit associated with decreases of 1.93 in physical function (95% CI -2.86 - -1.00, p<0.001), 1.62 in self-esteem (95% CI -2.67 - -0.57, p<0.05), 2.69 in public distress (95% CI -3.75 - -1.62, p<0.001), 1.33 in work (95% CI -2.63 - -0.02, p<0.05), and 1.79 in total IWQOL-Lite scores (95% CI -2.65 - -0.93, p<0.001). …”
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The Candida albicans Cdk8-dependent phosphoproteome reveals repression of hyphal growth through a Flo8-dependent pathway. by Jeffrey M Hollomon, Zhongle Liu, Scott F Rusin, Nicole P Jenkins, Allia K Smith, Katja Koeppen, Arminja N Kettenbach, Lawrence C Myers, Deborah A Hogan

“…In these studies, we generated a strain in which Ssn3 was replaced with a functional variant of Ssn3 that can be rapidly and selectively inhibited by the ATP analog 3-MB-PP1. …”
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Integrated multiple machine learning and Mendelian randomization reveal LTF gene as a prognostic biomarker for nonspecific orbital inflammation by Zixuan Wu, Jinfeng Xu, Yuan Gao, Kang Tan, Xiaolei Yao, Qinghua Peng

“…Enrichment analysis revealed that gene sets positively correlated with LTF were enriched in immune-related pathways. For biological function analysis in LTF, retina homeostasis, sensory perception of bitter taste, and tissue homeostasis were emphasized. …”
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Factors associated with D-dimer levels in HIV-infected individuals. by Alvaro H Borges, Jemma L O'Connor, Andrew N Phillips, Jason V Baker, Michael J Vjecha, Marcelo H Losso, Hartwig Klinker, Gustavo Lopardo, Ian Williams, Jens D Lundgren, INSIGHT SMART Study Group, ESPRIT Study Group, SILCAAT Scientific Committee

“…Covariates investigated were: age, gender, race, body mass index, nadir and baseline CD4+ count, plasma HIV RNA levels, markers of inflammation (C-reactive protein [CRP], interleukin-6 [IL-6]), antiretroviral therapy (ART) use, ART regimens, co-morbidities (hepatitis B/C, diabetes mellitus, prior cardiovascular disease), smoking, renal function (estimated glomerular filtration rate [eGFR] and cystatin C) and cholesterol.…”
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