Showing 981 - 1,000 results of 12,169 for search 'Negative function', query time: 0.14s Refine Results
  1. 981
  2. 982

    Nematode serine protease inhibitor SPI-I8 negatively regulates host NF-κB signalling by hijacking MKRN1-mediated polyubiquitination of RACK1 by Fei Wu, Yanqiong Chen, Xueqiu Chen, Danni Tong, Jingru Zhou, Zhendong Du, Chaoqun Yao, Yi Yang, Aifang Du, Guangxu Ma

    Published 2025-03-01
    “…Considering the structural and functional conservation of SPI-I8s among Strongylida nematodes and the conservation of interactive mediators (i.e., MKRN1 and RACK1) among mammals, our findings provide insights into the host-parasite interface where parasitic roundworms secret molecules to suppress host inflammatory responses. …”
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  3. 983

    Single-cell RNA sequencing reveals SLC31A1-mediated M2 polarization of macrophages promotes malignant progression in triple-negative breast cancer by Xiwei Zhang, Guoqing Li, Tieyan Chen, Haohang Sun, Ji Dai, Qi Chen, Mengze Chen, Meidi Yan

    Published 2025-05-01
    “…Abstract Background Among the various types of breast cancer that endanger women’s lives, triple-negative breast cancer (TNBC) stands out due to its extreme heterogeneity, aggressive nature, and high likelihood of recurrence. …”
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  4. 984

    Targeting PRDX2 to inhibit tumor growth and metastasis in triple-negative breast cancer: the role of FN1 and the PI3K/AKT/SP1 pathway by Jiawei Zhou, Anqi Cheng, Jianqiang Guo, Yafeng Liu, Xuan Li, Maoqian Chen, Dong Hu, Jing Wu

    Published 2025-04-01
    “…Abstract Background Triple-negative breast cancer (TNBC) is characterized by high invasiveness, high potential for metastasis, easy recurrence, and poor prognosis. …”
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    Article
  5. 985

    Current instability phenomena in a tunnel diode and electron self-organization processes by L.V. Chirkova, K.T. Ermaganbetov, K.M. Makhanov, K.S. Rozhkova, E.T. Arinova, A. Kurmash

    Published 2019-06-01
    “… In the article the mechanisms of electric instability in semiconductors are considered. The origin of negative differential conductivity of different types are described. …”
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  6. 986

    Impact of self-identity on social anxiety among college students: a moderated mediation model by Shuqi Guo, Jiazhong Yang, Shicong Zhang, Dongzhuo Xue, Mingxu Liu

    Published 2025-07-01
    “…BackgroundSocial anxiety is a prevalent and impairing condition among college students, often interfering with academic performance, emotional wellbeing, and social functioning.ObjectiveThis study aimed to test a moderated mediation model in which self-identity predicts social anxiety, with fear of negative evaluation (FNE) serving as a mediator and perceived social support acting as a moderator in the latter part of the pathway.MethodsA total of 328 college students (Mage = 19.48, SD = 1.02; 43.29% male) completed standardized self-report measures of self-identity, FNE, social anxiety, and perceived social support. …”
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  7. 987

    Unraveling Abnormal Thermal Quenching of Sub‐Gap Emission in β‐Ga2O3 by Zhengpeng Wang, Fei Tang, Fang‐Fang Ren, Hongwei Liang, Xiangyuan Cui, Shijie Xu, Shulin Gu, Rong Zhang, Youdou Zheng, Jiandong Ye

    Published 2025-01-01
    “…One channel is the nsnp‐ns2 transition of Sn2+, the other is donor‐acceptor pair recombination via (2VGa‐Sni)2− complex, which is energetically favorable as evidenced by density functional theory calculations. The semi‐classical quantum theory models fitting proves the transition from green to UV emissions with elevated temperature. …”
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  8. 988

    Altered structural and functional homotopic connectivity associated with cognitive changes in SLE by Chunlei Li, Yue Ma, Ning An, Sha Ni, Pengfei Qiao, Xueying Ma

    Published 2024-10-01
    “…Correlation analysis demonstrated that the increased VMHC values in insula was negatively correlated with decreased orientation function and positively correlated with decreased attention function. …”
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  9. 989

    THE EFFECT OF BLADDER PAIN SYNDROME/INTERSTITIAL CYSTITIS ON PARTNER SEXUAL FUNCTIONS by Kubilay Sarıkaya, Çağrı Şenocak, Muhammed Arif İbiş, Fahri Erkan Sadioğlu, Mehmet Çiftçi, Ömer Faruk Bozkurt

    Published 2022-01-01
    “…Objective: Bladder pain syndrome/Interstitial cystitis (BPS/IC) negatively affects both women’s social life and sexual functions. …”
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  10. 990

    A time for sex: circadian regulation of mammalian sexual and reproductive function by Sydney Aten, Oscar Ramirez-Plascencia, Chiara Blake, Chiara Blake, Gabriel Holder, Gabriel Holder, Emma Fishbein, Emma Fishbein, Adam Vieth, Adam Vieth, Arman Zarghani-Shiraz, Arman Zarghani-Shiraz, Evan Keister, Evan Keister, Shivani Howe, Shivani Howe, Ashley Appo, Ashley Appo, Beatrice Palmer, Carrie E. Mahoney

    Published 2025-01-01
    “…Evidence supporting the importance of proper clock function on fertility comes from several lines of work demonstrating that misalignment of biological rhythms or disrupted function of the body’s master clock, such as occurs from repeated shift work or chronic jet lag, negatively impacts reproduction by interfering with both male and female fertility. …”
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  11. 991

    Sex differences in the association between lipids and cognitive function in older adults by Jiahao Chen, Yinming Wang, Wenyan Guo, Muyuan Jiang, Zixuan Gai, Huinan Zhang, Mulei Chen, Yifan Fan

    Published 2024-12-01
    “…Background: It is well known that cognitive function is associated with gender differences. However, the effect of sex differences on the relationship between lipids fractions and cognitive function in older adults has been contentious. …”
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  12. 992

    Mediating effect of frailty on social isolation and cognitive function among the elderly by JIANG Meiting,YANG Wenfei,ZHANG Xiang,CAI Xin,GUAN Aijun,ZENG Dongyang

    Published 2025-01-01
    “…Mediating effect analysis showed that social isolation affected cognitive function directly and negatively with the effect value of -0.773 (95%CI: -0.899 to -0.647), and also affected cognitive function by frailty indirectly and negatively with the effect value of -0.147 (95%CI: -0.188 to -0.110), with the mediating effect contributed 15.98% of the total effect. …”
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  13. 993

    Cognitive function, sleep characteristics and their relationship in older adults with insomnia and anxiety by Jia Wei, Jin kun Zeng, Ruo bing Qi

    Published 2025-08-01
    “…The wake time after sleep (WASO) monitored by polysomnography was significantly longer than that in patients with simple insomnia disorder, and the duration of N3 and N3% were significantly shorter than that in patients with simple sleep disorder, with statistical significance (P < 0.05). Executive function was positively correlated with N3 duration and N3%, naming function was negatively correlated with N1 duration and N1%, and memory was negatively correlated with wake time after sleep (WASO) in insomnia patients with anxiety, (P < 0.05). …”
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  14. 994

    Age-related changes in vascular structure and function among obese women by D. P. Kotova, A. G. Avtandilov

    Published 2008-08-01
    “…The study aimed at investigating age-related changes in vascular structure and function among obese women. In total, 83 obese females and 45 women with normal weight were divided into four age subgroups. …”
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  15. 995
  16. 996

    Hyperbranched Polyethylene Ionomers Containing Quaternary Ammonium Ions and Their Functionalization of Nanomaterials by Zhibin Ye, Jalal Rahmatinejad, Bahareh Raisi, Peishuai Dai

    Published 2025-03-01
    “…With their unique hydrophobic hyperbranched polyethylene backbone, this class of ionomers enables the successful functionalization of negatively surface-charged nanomaterials, thus improving the processing and application of the latter. …”
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  17. 997

    Diagnosis of Functional Gastrointestinal Disorders and Choice of Treatment Regimen in Constipation Patients by I. V. Maev, A. N. Kazyulin, Yu. A. Kucheryavy, S. V. Cheryomushkin, A. Yu. Goncharenko, А. V. Gilyuk

    Published 2021-10-01
    “…Functional constipation commonly afflicts different ages and negatively impacts the quality of life. …”
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  18. 998

    Attentional and electrophysiological associations with executive function ability in young autistic children by Caroline Leahy, Samantha Major, Jill Howard, Kimberly L.H. Carpenter, Elena Tenenbaum, Lauren Franz, Saritha Vermeer, Jordan Grapel, Scott Compton, Marina Spanos, Geraldine Dawson

    Published 2025-07-01
    “…Abstract Difficulties in executive functioning (EF) have been consistently reported in autistic individuals, but less is known about the attentional and neural mechanisms driving these difficulties. …”
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  19. 999

    The Impact of Changing Ground-Floor Functions on Sidewalk Accessibility in Urban Spaces by Tuğçe Aladağ, Yelda Durgun Şahin

    Published 2025-07-01
    “…Changing functions of ground-floor units and their increasing outdoor expansions negatively impact sidewalk accessibility. …”
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  20. 1000

    Remembering the romantic past: Autobiographical memory functions and romantic relationship quality. by Cagla Aydin, Asuman Buyukcan-Tetik

    Published 2021-01-01
    “…In contrast, the social function served by the relationship events was positively associated, and the directive function was negatively associated with intimacy and relationship satisfaction. …”
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