Identification of SMYD2 as a candidate diagnostic and prognostic biomarker for gastric cancer by Sichao Wang, Chuanxi Zhao, Dongmei Li, Qingzhi Liu, Cuiping Mao, Shanshan Ding, Shujun Zhang, Wenjing Shang

“…Functional assays demonstrated that SMYD2 promoted GC cell proliferation, invasion, and migration in vitro.ConclusionsThese findings established SMYD2 is a major oncogene that can serve as a candidate diagnostic and prognostic biomarker for GC.…”
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Unveiling the versatility of the thioredoxin framework: Insights from the structural examination of Francisella tularensis DsbA1 by Stephanie Penning, Yaoqin Hong, Taylor Cunliffe, Lilian Hor, Makrina Totsika, Jason J. Paxman, Begoña Heras

“…Pathogenic bacteria often contain diverse Dsb proteins with distinct functionalities commonly associated with pathogenesis. …”
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Mechanisms of formation of hybrid immunity in people who recovered from COVID-19 and were vaccinated with SARS-CoV-2 peptide antigens by L. P. Sizyakina, I. I. Andrreeva, M. V. Kharitonova, N. S. Zaitseva, D. S. Lyubimov, V. Ya. Zakurskaya, Areg A. Totolian

“…The remaining differences in the functioning of the immune system identified in patients with COVID-19 before the vaccination in comparison with the control data have not changed. …”
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The oxytocin-oxytocin receptors system — a new pathogenetic mechanism in the development of diabetic phenotype of heart failure with preserved ejection fraction in women by A. D. Starchenko, Yu. V. Liskova, A. A. Stadnikov

“…To determine the pathogenetic role of the oxytocinergic system in the development of myocardium structural and functional changes in women with heart failure with preserved ejection fraction (HFpEF) associated with type 2 diabetes mellitus (DM2T) (diabetic phenotype of HFpEF).Material and methods. …”
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The insulator EACBE regulates V(D)J recombination of Tcrd gene by modulating chromatin organization by Yongchang Zhu, Yongchang Zhu, Ranran Dai, Ranran Dai, Hao Zhao, Junwei Luo, Keyi Li, Wei Xue, Litao Qin, Hongyuan Pan, Shixiu Liao, Bingtao Hao, Bingtao Hao

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The underlying molecular mechanisms and biomarkers of Hip fracture combined with deep vein thrombosis based on self sequencing bioinformatics analysis by Guanghua Shi, Xiaocui Shi, Meng Zhang, Rui Cheng, Mengqing Hu, Yu Zhao, Shimei Li, Xiuxiu Li, Haiyun Ma, Pengcui Li

“…Results Seven candidate genes were selected, with functional enrichment analysis linking them to the autophagosome and PPAR signaling pathways. …”
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Multi-omics analysis reveals the role of the autophagy-related gene AGT in chemotherapy resistance in colorectal cancer and the therapeutic potential of its inhibitors by Wenjiao Cai, Tao Xiang, Xiaoli Liu, Chong Fu

“…Through multi-omics analysis, this study explores the expression patterns, functions, and potential role of the autophagy-related gene Angiotensinogen (AGT) in colorectal cancer (CRC), particularly in relation to chemotherapy resistance. …”
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Nitrogen Supply Mitigates Temperature Stress Effects on Rice Photosynthetic Nitrogen Use Efficiency and Water Relations by Zhuang Xiong, Fangzhou Zheng, Chao Wu, Hui Tang, Dongliang Xiong, Kehui Cui, Shaobing Peng, Jianliang Huang

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Glucose stimulated CEST MRI pHe mapping for improved differentiation of tumors with altered hypoxia inducible factor 1alpha expression by Aruna Singh, Julia Stabinska, Balaji Krishnamachary, Farzad Sedaghat, Sridhar Nimmagadda, Jeff W. M. Bulte, Zaver M. Bhujwalla, Michael T. McMahon

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Quality of life and associated factors among patients with cancer receiving chemotherapy at Dessie Comprehensive Specialized Hospital, North-East Ethiopia: a cross-sectional study by Ewunetie Mekashaw Bayked, Mekdes Getachew Yimam, Zemen Mengesha Yalew, Husien Nurahmed Toleha, Segenet Zewdie

“…About 54.8% and 31.7% reported good overall health status and good overall QoL, respectively. The most impacted functional domain was social functioning, affecting 64.5% of participants. …”
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MicroRNA‐378a‐3p contributes to ovarian cancer progression through downregulating PDIA4 by Yao Chanjiao, Chen Chunyan, Qiu Xiaoxin, Han Youjian

“…Ovarian cancer OVCAR3 and SKOV3 cells were transfected or cotransfected with miR‐378a‐3p mimic or pcDNA3.1‐PDIA4 or their negative control plasmids to explore their roles in biological functions in ovarian cancer cells. …”
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Choline levels in the pregenual anterior cingulate cortex associated with unpleasant pain experience and anxiety by Lina Hudhud, Jón Hauksson, Michael Haney, Tobias Sparrman, Johan Eriksson, Lenita Lindgren

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Continuous Exposure to Low Doses of Ultrafine Black Carbon Reduces the Vitality of Immortalized Lung-Derived Cells and Activates Senescence by M. Esther Salinas, Denisse A. Gutiérrez, Armando Varela-Ramírez, Kristine M. Garza

“…The data suggested that compounding nanosized black carbon exposure could negatively impair overall pulmonary health by distinctively modifying intracellular behavior.…”
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Association of Platelet Binding to Lymphocytes with B Cell Abnormalities and Clinical Manifestations in Systemic Lupus Erythematosus by Carlos Zamora, Elide Toniolo, Cesar Diaz-Torné, Elisabet Cantó, Berta Magallares, Ma Angels Ortiz, Lidia Perea, Hector Corominas, Silvia Vidal

“…Immunological factors derived from platelets modulate B cell function in SLE disease. However, platelets do not only modify the immune system by soluble factors. …”
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Long noncoding RNA LINC00152 promotes cell proliferation through competitively binding endogenous miR‐125b with MCL‐1 by regulating mitochondrial apoptosis pathways in ovarian canc... by Puxiang Chen, Xiaolin Fang, Bing Xia, Yan Zhao, Qiaoyan Li, Xiaoying Wu

“…Abstract Recently, an increasing number of studies have focused on the key function of long noncoding RNAs (lncRNAs) in biological activity. …”
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Alternate nostril breathing (Nadi-Shodhana Pranayama) and its impact on perceived stress and hearing threshold among medical students; a prospective study by Smitha Nagendrappa, Sudhir Goppenahalli Kumaraswamy, Vinay Hosagavi Ramalingaiah

“…Background: Medical students often experience significant psychological stress, which can negatively impact their academic performance, cognitive functions, and overall well-being. …”
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Early Season Precipitation Addition Offsets Warming Effect on Carbon and Water Use Efficiency in Qinghai–Xizang Plateau by Ayisha Oyont, Zheng Li, Guozheng Hu, Shicheng He, Youxia Wang, Jun Yan, Hasbagan Ganjurjav, Qingzhu Gao

“…Carbon and water fluxes are critical indicators of grassland ecosystem function and are sensitive to climate change. However, how seasonal precipitation changes interact with warming to affect alpine grassland carbon and water use efficiency (CUE and WUE) remains unclear. …”
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Morphophysiology and production of West Indian cherry under salt stress and nitrogen-phosphorus-potassium fertilization by Leandro de P. Souza, Geovani S. de Lima, Hans R. Gheyi, Reynaldo T. de Fátima, André A. R. da Silva, Reginaldo G. Nobre, Lauriane A. dos A. Soares, Cassiano N. de Lacerda

“…In this context, the objective of this study was to evaluate the morphophysiology and production of the West Indian cherry ‘Flor Branca’ as a function of irrigation with waters of different electrical conductivities and fertilization with nitrogen-phosphorus-potassium combinations. …”
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Transcriptional Signatures of the Right Ventricle in End‐Stage Heart Failure by Jonah D. Garry, Giovanni E. Davogustto, Vineet Agrawal, Fei Ye, Kelsey Tomasek, Yan Ru Su, Tarek Absi, James D. West, Anna Hemnes, Evan L. Brittain

“…Pathways related to fatty acid metabolism and mitochondrial function were negatively enriched, while extracellular structure‐related pathways were positively enriched in stressed RVs (compensated and failing) compared to controls. …”
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Early detection of positive urine culture in patients with urolithiasis: a machine learning model with dynamic online nomogram by Di Luo, Jingdong Zhang, Linguo Xie, Chunyu Liu, Rui Wang

“…Online nomograms were developed and evaluated for performance through metrics such as area under the curve (AUC), calibration curve, decision curve analysis (DCA), probability density function (PDF), and clinical utility curve (CUC).Results Multivariate logistic analysis identified four significant predictors—bacteria (BACT), C-reactive protein (CRP), nitrite, and leukocyte esterase (LEU)—which were integrated into the nomogram. …”
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