Association of cardiovascular-kidney-metabolic index with all-cause mortality during hospitalization in critically ill patients: a retrospective cohort study from MIMIC IV2.2 by Xiaolong Qu, Yuping Liu, Peng Nie, Lei Huang

“…BackgroundThe cardiovascular-kidney-metabolic index (CKMI), a novel functional indicator proposed in this study, aims to accurately reflect the functional status of the heart, kidneys, and metabolism. …”
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Effective Protection Against Status Epilepticus Caused by Lithium–Pilocarpine: Combination of Midazolam and Lacosamide by Cumaali Demirtas, Metehan Akca, Ugur Aykin, Yunus Emre Surmeneli, Hava Yildirim, Mehmet Yildirim

“…Additionally, it was observed that LEV, LCM, and VPA administered together with MDZ did not negatively affect both cognitive and motor functions.…”
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Reverse transcriptase inhibitors diminish systemic proinflammatory responses to bacterial pathogens by Karthik Hullahalli, Katherine G. Dailey, Ryan Acbay, Masataka Suzuki, George I. Balazs, Matthew K. Waldor

“…Our findings indicate that uncovering the mechanisms underlying the anti-inflammatory functions of reverse transcriptase inhibitors may lead to new therapeutics for bacterial infectious diseases.…”
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Clarifying the adverse effect of secondary phase on the tribological property of Mg alloy by Jie Li, Ting Zou, Junjie Yang, Helong Yu, Peng Zhang, Xiaochao Ji, Xin Zhao, Zhiyong Yan, Wei Li

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Development of Antimicrobial and Antioxidative Chicken Patties Using Liquid-Fermented <i>Ganoderma lucidum</i> and <i>Pleurotus djamor</i> Fruiting Body Biomass by Nur Asyiqin Zahia-Azizan, Chong Shin Yee, Muhammad Ameer Ushidee-Radzi, Zul Ilham, Muhamad Hafiz Abd Rahim, Siva Raseetha, Nazimah Hamid, Adi Ainurzaman Jamaludin, Wan Abd Al Qadr Imad Wan-Mohtar

“…These were compared to a negative control (0% mushroom flour chicken patty) and a commercial patty. …”
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Sub-Lethal Effects of Predators in Aquaculture: Assessment of Chronic Exposure to Conspecific Alarm Substance on Feeding and Growth Performances of Nile Tilapia by Rafaela Torres Pereira, Alexandre Luiz Arvigo, Caio Akira Miyai, Augusto Rysevas Silveira, Percília Cardoso Giaquinto, Helton Carlos Delicio, Leonardo José Gil Barcellos, Rodrigo Egydio Barreto

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Evaluation of antibacterial activity of Bacillus velenesis 21-128 against Xanthomonas campestris pv. Campestris by Moon Joo Kim, Eun-Jae Park, Bori Lee, Hyun-Jae Jang, Jongmin Ahn, Ji-Hye Kim, Young Ho Kim, Bong-Sik Yun, Seung Woong Lee

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Heterogeneity of CD8αα intraepithelial lymphocytes is transcriptionally conserved between TCRαβ and TCRγδ cell lineages by Kaito A. Hioki, Kaito A. Hioki, Kaito A. Hioki, Xueting Liang, Xueting Liang, Adam C. Lynch, Adam C. Lynch, Adam C. Lynch, Ravi Ranjan, Elena L. Pobezinskaya, Leonid A. Pobezinsky, Leonid A. Pobezinsky

“…Further transcriptional analysis revealed shared profiles between TCRαβ+ and TCRγδ+ small intestinal IEL subsets, suggesting conserved functional roles across these populations. Finally, our analysis indicated that TCRαβ+ memory-like IELs arise from Tcf7+ double-negative (DN) precursors, and that effector-like IELs subsequently differentiate from the memory-like population. …”
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Methylation-modulated PFTK1 regulates gefitinib resistance via Wnt/β-catenin signaling in EGFR mutant non-small-cell lung cancer cells by Xiaoting Jia, Jingjie Tian, Pingping Chen, Jing Dong, Lei Li, Danyang Chen, Jianlei Zhang, Dongjiang Liao, Zhimin He, Kai Luo

“…And the upregulation of PFTK1 is negatively associated with progression-free survival (PFS) in NSCLC patients who receive gefitinib treatment. …”
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Atypical hierarchical brain connectivity in autism: Insights from stepwise causal analysis using Liang information flow by Shan Sun, Fei Wang, Fen Xu, Yufeng Deng, Jiwang Ma, Kai Chen, Sheng Guo, X. San Liang, Tao Zhang

“…In this study, we applied the Liang information flow method to analyze stepwise causal functional connectivity in ASD, offering a novel approach to understanding how different brain networks interact. …”
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Pro-inflammatory role of neutrophils populations in trauma patients: monitoring neutrophil populations by Marcela Vlková, Marcela Vlková, Julie Štíchová, Julie Štíchová, Karolína Surá, Karolína Surá, Karolína Dvořáková, Karolína Dvořáková, Vojtěch Kunčický, Vojtěch Kunčický, Ioanna Papatheodorou, Ioanna Papatheodorou, Gabriela Blažková, Zuzana Tomášiková, Zuzana Tomášiková, Kamila Bendíčková, Kamila Bendíčková, Ludmila Dohnálková, Alexandra Mýtniková, Alexandra Mýtniková, Alexandra Mýtniková, Jan Žák, Jan Kovařík, Milan Krtička, Tomáš Tomáš, Vladimír Šrámek, Martin Helán, Martin Helán, Anna Kocurková, Anna Kocurková, Anna Kocurková, Jan Frič, Jan Frič, Jan Frič, Marcela Hortová-Kohoutková, Marcela Hortová-Kohoutková

“…Neutrophil subsets were analyzed at two time points (TP1 and TP2) using flow cytometry. Functional assays evaluated phagocytosis, oxidative burst, mitochondrial function, and degranulation. …”
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Is obesity a contributing factor to female infertility? - a literature review by Marta Frank, Dawid Falkowski, Magdalena Kozłowska, Gracjan Kozłowski, Julia Łabuda, Urszula Rewaj-Nowicka, Jowita Szwedo

“…Furthermore, obesity negatively impacts oocyte quality, endometrial receptivity, and the success of assisted reproductive technologies (ART), such as in vitro fertilization (IVF). …”
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Effects of Increasing Levels of Anthropization and Land Use on Nosema spp. Spore Loads by Cristina Gabriela MATHE, Gianluca ALBANESE, Alexandru Ioan GIURGIU, Tudor Nicolas TERNAR, Otilia BOBIȘ, Claudia PAȘCA, Melinda Maria TÓFALVI, Antonio DE CRISTOFARO, Daniel Severus DEZMIREAN

“…In addition, high population density in hives could negatively impact bee health. Aims: Investigate the presence of Nosema spp. as a function of apiary size, beekeeping practices, proximity between apiaries, and land use. …”
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The Role of Oxidative Stress in Skin Disorders Associated with Alcohol Dependency and Antioxidant Therapies by Joanna Wróblewska, Anna Długosz, Damian Czarnecki, Wioletta Tomaszewicz, Błażej Błaszak, Joanna Szulc, Weronika Wróblewska

“…Alcohol dependency is a complex and chronic condition that negatively impacts multiple organ systems, including the skin. …”
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Treatment outcomes in patients with seropositive versus seronegative rheumatoid arthritis in Phase III randomised clinical trials of tofacitinib by Peter Nash, Stephen Hall, Paul Bird, Carol A Connell, Kenneth Kwok, David Witcombe, Krishan Thirunavukkarasu

“…‘Serotype’ subgroups were: anticyclic citrullinated peptide (CCP) and rheumatoid factor (RF) positive (anti-CCP+/RF+); anti-CCP+/RF negative (-); anti-CCP-/RF+; anti-CCP-/RF-. At month 3, ACR20/50/70 response rates, Disease Activity Score (DAS28-4[ESR])-defined remission (DAS28-4[ESR]&lt;2.6) and low disease activity (LDA; DAS28-4[ESR]≤3.2), changes from baseline (CFB) in Health Assessment Questionnaire-Disability Index (HAQ-DI), Short Form-36 Health Survey (SF-36) physical functioning and Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) were evaluated. …”
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Neuroprotective properties of GABA and its derivatives in diabetic encephalopathy in old animals by I. N. Tyurenkov, D. A. Bakulin, A. V. Smirnov, M. R. Ekova, A. I. Bisinbekova, G. L. Snigur, Yu. I. Velikorodnaya, E. I. Morkovin, D. V. Verkholyak, O. S. Vasilyeva

“…After 6 weeks of the administration, GABA and its compositions in old animals (19 months old) significantly improved sensory-motor and cognitive functions, reduced negative structural changes in the hippocampus and somatosensory cerebral cortex.…”
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Impact of specific productivity and operation mode upon the biophysical properties of HIV-1 Gag-based virus-like particles by Pol Pérez-Rubio, Elianet Lorenzo Romero, Josefina Casas, Andy Díaz-Maneh, Francesc Gòdia, Laura Cervera, Jesús Lavado-García

“…Both perfusion-derived nanoparticles achieved functionalization rates of 2800 Cy5/TP. On the contrary, those nanoparticles produced in batch yielded functionalization rates below 1000 Cy5/TP. …”
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Ecosystem services and multifunctionality are co-regulated by biotic and abiotic factors along with forest types in a temperate forest of South Korea by Min-Ki Lee, Yong-Ju Lee, Jung-Hwa Chun, A-Reum Kim, Chang-Bae Lee

“…., species diversity, functional dominance, stand structural diversity) and abiotic (i.e., topography, climate, and soil) factors, and stand age on EMF and each ecosystem service category. …”
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Socioecological factors linked to co-occurring early childhood sleep health disparities and developmental outcomes: protocol for the sleep in preschoolers cross-sectional study by Darko Stefanovski, Ignacio E Tapia, Wanjikũ F M Njoroge, Rebecca Waller, Tiffani J Johnson, Eberechukwu A Uwah, Olivia Cicalese, Brizhay Davis, Megha Neelapu, Gabriel Steinberg, Arun Handa, Jodi A Mindell, Ariel A Williamson

“…These sleep deficiencies are more common in racial and ethnic minoritised children and have significant negative impacts on neurobehavioural and social-emotional development. …”
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Hsa-miR-7974 Suppresses Epstein-Barr Virus Reactivation by Directly Targeting <i>BZLF1</i> and <i>BRLF1</i> by Haotian Li, Hui Wang, Jiao Wang, Xuexin Lu, Jieqiong Zhang, Mingming Wang, Dongbo Yu, Ying Li, Shiwen Wang

“…These findings establish that miR-7974 functions as a crucial negative regulator of EBV reactivation by directly targeting BRLF1, highlighting its potential significance in the pathogenesis of EBV-associated malignancies.…”
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