Suggested Topics within your search.
Suggested Topics within your search.
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9721
stGRL: spatial domain identification, denoising, and imputation algorithm for spatial transcriptome data based on multi-task graph contrastive representation learning
Published 2025-07-01“…This significantly enhances researchers' understanding of cellular and tissue functions in their spatial context. However, due to current technical limitations, spatial transcriptomics data often exhibit high dropout rates and noise, posing challenges for downstream analysis, like spot clustering, differential gene analysis, and spatial domain identification. …”
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9722
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9723
Characteristics of the vaginal microbiota and vaginal metabolites in women with cervical dysplasia
Published 2024-10-01“…Additionally, Lactobacillus was found to be negatively associated with bacterial diversity and bacterial metabolic functions, which increased with the degree of cervical lesions and cancer. …”
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9724
The death education needs of patients with advanced cancer: a qualitative research
Published 2024-11-01“…Patients with advanced-stage cancer contend with both physical challenges such as pain, physical decline, and functional impairments, as well as psychological issues including death anxiety, fear of death, and feelings of meaninglessness and hopelessness during disease treatment. …”
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9725
Investigating the effect of positive psychology on improving hope, happiness and psychological flexibility of female elementary school teachers in Rafsanjan city
Published 2024-09-01“…Background: Positive psychology is the scientific study of optimal and desirable human functions. Psychologists following this trend claim that their techniques not only reduce the level of depression in individuals and societies, but also teach people the right way to live and, as a result, satisfaction with life and ultimately happiness. …”
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9726
Benefits of Probiotics—Biodetoxification
Published 2025-05-01“…In addition, probiotics in food are associated with well-known human health benefits; therefore, as a functional food, they have gained common consumer acceptance. …”
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9727
Monitoring of administrative accounts regulating tourist activity in Russia (on the Example of social network “Vkontakte”)
Published 2021-02-01“…The methodological framework of the study is the structural-functional approach. The subject of the analysis is the communication activity of official accounts of the authorities involved in the regulation of the tourism industry in the capital and regions in the social network “Vkontakte” (as the most popular in Russia). …”
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9728
Exploring benefits of speech and language therapy interventions for post-stroke aphasia rehabilitation: A qualitative study
Published 2025-02-01“…Speech therapists described using a combination of impairment and functional/communication-based interventions to improve the communication skills and social participation of their clients with aphasia. …”
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9729
A reproducible ddRAD-seq protocol reveals novel genomic association signatures for fruit-related traits in peach
Published 2025-07-01“…Candidate causal genes were shortlisted when fulfilling the following criteria: (i) position within the linkage disequilibrium block, (ii) functional annotation and (iii) expression pattern. …”
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9730
Structural and optical characterization of TiO2 nanoparticles synthesized using Globularia alypum leaf extract and the antibacterial properties
Published 2025-07-01“…Fourier Transform Infrared spectroscopy analysis of GA showed characteristic peaks for various functional groups that mediated the formation of the TiO2 nanoparticles. …”
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9731
Extracts from Tartary Buckwheat Sprouts Restricts Oxidative Injury Induced by Hydrogen Peroxide in HepG2 by Upregulating the Redox System
Published 2024-11-01“…Present work revealed the potential health benefits of TBS and provided a test basis for developing functional food of TBS.…”
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9732
Health-Related Quality of Life Among Patients Who Have Survived an Episode of Sepsis in the United States: A Systematic Review
Published 2025-01-01“…Studies examined the effects of sepsis on the following outcomes of interest: HRQoL (4 studies), physical functioning (5 studies), cognitive status (3 studies), and psychological well-being (3 studies). …”
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9733
Adherence to statin therapy in patients with high and very high cardiovascular risk in real clinical practice
Published 2020-03-01“…The target level of LDL-С was achieved in 13 (25%) patients. 38 (72%) patients showed a decrease in cognitive functions; a positive correlation was found between adherence and the MoCA test (r = 0.44, p = 0.04). …”
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9734
Dry eye masky syndrome: degree of expression and possibilities of correction
Published 2022-07-01“…Appointment of tear replacement therapy allowed to improve the functional indicators of tears and quality of life. …”
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9735
Construction of the porcine genome mobile element variations and investigation of its role in population diversity and gene expression
Published 2024-12-01“…We found that MEVs are unevenly distributed across the genome and are strongly influenced by negative selection effects. Importantly, we identified 514, 530, and 584 candidate MEVs associated with population differentiation, domestication, and breed formation, respectively. …”
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9736
Identification of therapeutic targets in lung adenocarcinoma using Mendelian randomization and multi-omics
Published 2025-06-01“…The prognostic relevance of the identified candidate targets was assessed using transcriptomic data. Functional interactions were explored via protein–protein interaction network analysis, while single-cell analyses were employed to determine cell-specific expression patterns and differentiation trajectories. …”
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9737
MiR-494-3p knockdown promotes osteogenic differentiation of bone marrow mesenchymal stem cells in ovariectomised rats by targeting Sirt1/TLR4/NF-κB pathway
Published 2025-06-01“…Then, BMSCs were transfected with miR-494-3p inhibitor/mimic, si-Sirt1 and negative controls as well as pcDNA3.1-TLR4 and empty pcDNA3.1 vector. …”
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9738
INTERACTION BETWEEN SYMPATHO-ADRENAL ACTIVITY AND IMMUNE MEDIATORS IN PATIENTS WITH METABOLIC SYNDROME
Published 2014-03-01“…To investigate the interactions between the functional status of sympathoadrenal system and immune meditators in patients with metabolic syndrome (MS).Material and methods. …”
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9739
Zangezur and South Araz Transport Projects: Problems of Implementation in the Context of Relations between Armenia, Iran and Azerbaijan
Published 2024-08-01“…Due to the destructive policy of the Armenian leadership, the legal framework for unblocking the Zangezur transport corridor and ensuring its functioning under Russian neutral control has been destroyed. …”
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9740
Effect of Full Mouth Oral Rehabilitation on Bite Force and Body Mass Index in Patients with Early Childhood Caries: A Study Protocol
Published 2024-11-01“…Untreated dental caries can lead to malnutrition, linear growth failure and a negative Body Mass Index (BMI). Need of the Study: Bite force assessment in the context of full-mouth rehabilitation of ECC will help measure functionality, monitor stability, finding issues early, ensuring treatment effectiveness and recommend any necessary adjustments for the child’s best dental health, to improve post-treatment quality of life. …”
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