Faecal mucoprotein MUC2 is decreased in multiple sclerosis and is associated with mucin degrading bacteriaResearch in context by Luke A. Schwerdtfeger, Federico Montini, Tanuja Chitnis, Laura M. Cox, Howard L. Weiner

“…Microbiota with known mucus degrading capacity were elevated in the stool of subjects with MS and negatively correlated with mucus protein levels. Interpretation: Taken together, these findings suggest reduced gut barrier function in MS which is linked to increased mucin degrading bacteria. …”
Get full text

How the perceived substitution of AI technology hinders nurses’ innovation behavior: the mediating role of AI anxiety and human-AI cooperation intention and the moderating role of... by Jianpeng Fan, Leilei Zhang, Ning Li, Shuyu Man

“…This study, using Mplus8.0, analyzed 394 survey responses and found the following: (1) The perceived substitution of AI technology is significantly negatively correlated with nurses’ innovation behavior (β = − 0.16, p < .001); (2) AI anxiety acts as a mediator between the perceived substitution of AI technology and nurses’ innovation behavior (β = − 0.08, p < .01); (3) Human-AI cooperation intention also acts as a mediator between the perceived substitution of AI technology and nurses’ innovation behavior (β = − 0.09, p < .001); (4) AI anxiety and human-AI cooperation intention together function as a chain mediator between the perceived substitution of AI technology and nurses’ innovation behavior (β = − 0.05, p < .05); (5) Organizational AI readiness moderates the relationship between the perceived substitution of AI technology and nurses’ innovation behavior (β = 0.05, p < .05). …”
Get full text

Acute kidney injury and outcomes in hospitalized children with autoimmune rheumatic disease by Chien-Hung Lin, Wen-Sheng Liu, Chuan Wan, Hsin-Hui Wang

“…Abstract Background Autoimmune rheumatic diseases (ARDs) in children can negatively impact renal function, potentially leading to acute kidney injury (AKI). …”
Get full text

Influence of Chronotype and Theobromine on the 24-h Variation in Peak Expiratory Flow Rate in Healthy Adults by Anika Köhlmoos, Manuela Dittmar

“…The influence of morningness-eveningness preference and dietary components on the circadian variation in peak expiratory flow (PEF), an established criterion for pulmonary function, is not fully understood. This study aimed to investigate (a) how the chronotype influences the 24-h variation in PEF and (b) whether the bronchodilator theobromine affects this variation differently in different chronotypes. …”
Get full text

The Reliability of the GNRB® Knee Arthrometer in Measuring ACL Stiffness and Laxity: Implications for Clinical Use and Clinical Trial Design by Kayla Smith, Nicole Miller, Steve Laslovich

“…Greater knee joint laxity appears to negatively affect dynamic joint function and therefore reliable and valid measures of ACL stiffness and laxity are clinically valuable…”
Get full text

The Role of E-Cadherin in the Assessment of Esophageal Mucosal Damage in Patients with Gastroesophageal Reflux Disease Associated with Obstructive Sleep Apnea/Hypopnea Syndrome by Y. Ya. Shaukovich

“…A positive dependence of E-cadherin concentration in the blood plasma on the apnea/hypopnea index was found (r = 0.43, p &lt;0.05).Conclusions. OSAHS negatively affects the state of histoarchitecture of the esophageal mucosa of GERD patients, as evidenced by an increase in N-terminal E-cadherin in the blood plasma and may indicate a loss of E-cadherin in the esophageal mucosa with the development of an impaired function of tight junctions.…”
Get full text

Anti-PD-1 antibody enhances homeostatic proliferation–induced antitumor immunity during lymphopenia recovery by Zike Yang, Ying Zhu, Qian Wang, Qing Lin, Yahui Liu

“…The PD-1/PD-L1 axis was blocked using anti-PD-1 antibodies to assess its impact on T-cell function, dendritic cell (DC) activation, and memory T-cell differentiation.ResultsAlthough T cells proliferated continuously in lymphopenic mice, IFN-γ+ CD8+ T cells declined over time. …”
Get full text

Acoustic Properties of Recycled Polyurethane Foam Waste and Polyvinyl Acetate Composites by Tubelis Jonas, Astrauskas Tomas, Dzikēvičs Miķelis

“…Research was performed using standard transfer function (ISO 10534-2) and transfer matrix (ASTM E2611) methods. …”
Get full text

Talus Avascular Necrosis: Demographics, Epidemiology, and Activity Level by Akhil Sharma, Urvi J Patel, Rishin J Kadakia, Aman Chopra, Selene Parekh

“…Conclusion: Patients with talar AVN present with significant pain and limitation that negatively impacts their daily functioning. Our results demonstrate that patients report at least 50% loss in ability to function with regard to ADLs and almost a 75% loss in sporting-related activities. …”
Get full text

Clinical significance of parathyroid hormone in mineral and glucose metabolism disorders among patients with primary aldosteronism by Zhilian Sun, Wenxiu Liu

“…Biochemical indices including parathyroid hormone, serum potassium, serum calcium, urine potassium, urine calcium, plasma renin, plasma aldosterone, glycosylated hemoglobin, insulin resistance index, and pancreatic beta cell function index were compared among the three groups. …”
Get full text

Effects of mindfulness meditation on human impulsivity: a systematic review and meta-analysis by Eric W. Tsang, Junling Gao, Chi Ngai Lo, Nicholas T. Trapp, Aaron D. Boes, Hinhung Sik

“…Furthermore, MM appears to be a versatile cognitive strategy that is suitable for individuals of various ages and beneficial for addressing mental health issues influenced by impulse control, including aggression, addictions, and executive function impairments.…”
Get full text

The correlation between positive rate of antibody or DNA and children’s age with suspected Mycoplasma pneumoniae infection by Weiguo Feng, Ying Lin, Qiang Wang, Xiaoqin Qian

“…Laboratory data showed mild elevations in inflammatory markers and normal liver function tests, reflecting the generally moderate severity of MP infections. …”
Get full text

Assessing Fetal Circulatory Changes in Gestational Diabetes via Aortic Isthmus Doppler by Xingxing Chen, Lili Zhang, Jiajia Lu, Lijun Shen

“…Background: Gestational diabetes mellitus (GDM) is a common complication during pregnancy that can negatively impact fetal heart function and structure. …”
Get full text

Characterisation of guided entry of tail-anchored proteins in Magnaporthe oryzae. by Felix Abah, Qiaojia Zheng, Xinru Chen, Linwan Huang, Xiaomin Chen, Jules Biregeya, Osakina Aron, Zonghua Wang, Wei Tang

“…In summary, this finding provides valuable insight into the biological functions of the GET components in plant fungal pathogens.…”
Get full text

A mixed herbal extract as an adjunctive therapy for attention deficit hyperactivity disorder: A randomized placebo-controlled trial by Sujin Bae, Sunhye Park, Doug Hyun Han

“…Changes in ADHD symptoms (K-ARS scores), as well as brain activity and functional connectivity, were assessed at baseline and 4 weeks later. …”
Get full text

LD-aminopterin in the canine homologue of human atopic dermatitis: a randomized, controlled trial reveals dosing factors affecting optimal therapy. by John A Zebala, Alan Mundell, Linda Messinger, Craig E Griffin, Aaron D Schuler, Stuart J Kahn

“…However, recent in vitro studies indicate that AICAR increases then decreases as a function of antifolate concentration. To address this issue and understand how dosing affects antifolate efficacy in AD, we examined the efficacy and safety of different oral doses and schedules of LD-aminopterin in the canine model of AD.…”
Get full text

Jugular Venous Oxygen and Lactate Parameters for Predicting Early Cognitive Dysfunction after Off-Pump Coronary Artery Bypass Grafting: A Prospective Observational Study by Pooja Singh, Ramees A Anchukandan, Sunaina T Karna, Yogesh Niwariya, Vaishali Waindeskar, Harish Kumar, SRAN Bhushanam Padala, Molli Kiran

“…Background and Objectives: The quality of life may be negatively impacted by postoperative cognitive dysfunction (POCD) following off-pump coronary artery bypass grafting (OPCAB). …”
Get full text

Effect of Feeding Sugarcane Bagasse-Extracted Polyphenolic Mixture on the Growth Performance, Meat Quality, and Oxidative and Inflammatory Status of Chronic Heat-Stressed Broiler C... by Motoi Kikusato, Fu Namai, Katsushige Yamada

Get full text

miR-324-5p inhibits gallbladder carcinoma cell metastatic behaviours by downregulation of transforming growth factor beta 2 expression by Xinrong Zhang, Lei Zhang, Ming Chen, Dongying Liu

“…However, the biological function and molecular mechanism of miR-324-5p in GBC still remain largely unknown. …”
Get full text

Effects of silencing StSOBIR1-like gene on potato in response to herbivory by HE Wenjing, ZHANG Yadong, ZHANG Chao, ZHONG Jian, CHEN Chuzhen, GE Yang, HE Shuyan, ZHU Zengrong, ZHOU Wenwu

“…In summary, StSOBIR1-like gene might negatively regulate potato response to herbivory. This study analyzed the function of StSOBIR1-like gene in potato response to herbivory for the first time, which provides a basis for further exploring the molecular mechanism of this gene in regulating insect resistance of crop.…”
Get full text