How 2D and 3D Built Environment Impact Urban Vitality: Evidence from Overhead-Level to Eye-Level Urban Form Metrics by Yi Peng, Xu Cui, Bingjie Yu, Runze Liu, Hong Li

“…., normalized difference vegetation index (−0.092), green view index (−0.104), road density (−0.021), and enclosure (−0.089)) are negatively correlated with urban vitality, while the indicators of building space and mixed function (e.g., building density, floor area ratio, points of interest (POI) mixing degree, and 3D mixing degree) present a positive effect. …”
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The antioxidant system in rabbit under combine action of severe heat stress and nanoparticles of zinc, selenium, and germanium citrate by M. O. Yuzviak, Y. V. Lesyk, Y. T. Salyha

“…It is generally known that rabbits cannot effectively ensure thermoregulation of their body at temperatures above 18-21°C due to the absence of sweat glands and thick fur. Heat stress negatively affects the metabolic processes and reproductive function of rabbits. …”
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LINC00365 promotes miR-221-5p to inhibit pyroptosis via Dicer in colorectal cancer by Yang Weiqing, Huang Xiang, Lv Weibin, Jin Yuelong, Zhu Yiping

“…Additionally, LINC00365 was confirmed to be positively correlated with miR-221-5p, and miR-221-5p is negatively correlated with gasdermin-D (GSDMD) in colorectal cancer tissues. …”
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Toward streamline variant classification: discrepancies in variant nomenclature and syntax for ClinVar pathogenic variants across annotation tools by Yu-An Chen, Tzu-Hang Yuan, Jia-Hsin Huang, Yu-Bin Wang, Tzu-Mao Hung, Chien-Yu Chen, Pei-Lung Chen, Jacob Shujui Hsu

“…The substantial discrepancies were noted in the loss-of-function (LoF) category. Incorrect PVS1 interpretations affected the final pathogenicity and downgraded PLP variants (ANNOVAR 55.9%, SnpEff 66.5%, VEP 67.3%), risking false negatives of clinically relevant variants in reports. …”
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Bivariate Frequency Analysis of Extreme Sea Level with Rainfall and Temperature in New York City by Ali Razmi, Emad Mahjoobi, Heydar Ali Mardani-Fard, Zahra Zahmatkesh

“…Climate change negatively impacts hydrologic patterns, affecting rainfall, temperature extremes, and sea level rise. …”
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Primary Orbital Marginal Zone B-cell Lymphoma: A Rare Case Report by Ranjana Giri, Nageswar Sahu, Prita Pradhan, Dhanasree Surendran Vellikal, Goutami Das Nayak

“…Immunohistochemistry (IHC) showed positivity for CD20, CD79a, PAX5, and Bcl2, and negativity for CD3, CD5, CD10, CD23, Bcl6, and Cyclin-D1. …”
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Fine-Grained Style Alignment and Class Balance for Unsupervised Domain Adaptation in Remote Sensing Image Segmentation by Yousheng Xu, Weiji Wang, Wei Yao, Shengzhou Xu

“…Second, we propose a class balance loss function that adjusts the weight distribution of target domain samples to mitigate the influence of dominant classes and enhance the focus on rare categories, thereby alleviating the issue of class imbalance. …”
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Advancements in Visual Field Testing: A Systematic Review of the 24-2C Test Grid by Eric Jin, Natalie Shi Qi Wong, Claire Xin Yi Goh, Michael W. Stewart, Syril Dorairaj, Bryan Chin Hou Ang

“…Studies comparing conventional visual field (VF) indices, ability to detect central visual field defects (CVFDs), structure–function (S-F) concordance, and test characteristics across the HVF 24-2C SITA-Faster, 24-2 SITA-Standard/Faster, and 10-2 SITA-Standard/Fast tests were included. …”
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Increase in the constrictor effects of Rho-kinase in skeletal muscle and coronary arteries of rats with chronic hypothyroidism by D. K. Gaynullina, E. K. Selivanova, A. P. Sharova, O. S. Tarasova

“…The deficit of thyroid function is known to be accompanied by an increase in the overall peripheral vascular resistance. …”
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TIM‐4 increases the proportion of CD4+CD25+FOXP3+ regulatory T cells in the pancreatic ductal adenocarcinoma microenvironment by inhibiting IL‐6 secretion by Ziyao Wang, Zerong Xie, Yu Mou, Ruiman Geng, Chen Chen, Nengwen Ke

“…Abstract Background Currently, creating more effector T cells and augmenting their functions is a focal point in pancreatic ductal adenocarcinoma (PDAC) treatment research. …”
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An increase in visceral fat is associated with a decrease in the taste and olfactory capacity. by Jose Carlos Fernandez-Garcia, Juan Alcaide, Concepcion Santiago-Fernandez, M M Roca-Rodriguez, Zaida Aguera, Rosa Baños, Cristina Botella, Rafael de la Torre, Jose M Fernandez-Real, Gema Fruhbeck, Javier Gomez-Ambrosi, Susana Jimenez-Murcia, Jose M Menchon, Felipe F Casanueva, Fernando Fernandez-Aranda, Francisco J Tinahones, Lourdes Garrido-Sanchez

“…<h4>Results</h4>We found a lower score in the measurement of smell (TDI-score (Threshold, Discrimination and Identification)) in obese subjects. All the olfactory functions measured, such as threshold, discrimination, identification and the TDI-score, correlated negatively with age, body mass index (BMI), leptin, fat mass, fat-free mass and VFR. …”
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Sexuality Assessment in Women Diagnosed with Ovarian Cancer by Patricio Jaramillo Guerrero, Edison Enrique Sotalin Nivela, Eduardo Leonel Alvarado Pico

“…<strong>Foundation:</strong> sexual life disorders can negatively affect self-esteem and social relationships, especially in patients undergoing gynecological surgery and oncological treatment. …”
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CircPWWP2A promotes renal interstitial fibrosis through modulating miR-182/ROCK1 axis by Qian Huang, Kaiyi Zhong, Jiali Wei

“…Renal fibrosis is a long-term and progressively worsening condition that impacts kidney function during aging and in the context of chronic kidney disease (CKD). …”
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Polymorphonuclear myeloid-derived suppressor cells regulates immune recovery during HIV infection through PD-L1 and TGF-β pathways by Zihua Wang, Yue Hu, Jing Song, Ping Ma, Huan Xia

“…Furthermore, we investigated the impact of the blockade of PD-L1 and TGF-β pathways on MDSCs and their effects on CD4+ T-cells using in vitro functional experiments.ResultsPMN-MDSCs are more abundant and are negatively correlated to CD4 counts in HIV-infected individuals. …”
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Roles of microRNA let-7b in papillary thyroid carcinoma by regulating HMGA2 by Hongguang Li, Lihong Zhao, Zhenhua Zhang, Heng Zhang, Chao Ding, Zijie Su

“…Let-7b might function as a tumor suppressor in papillary thyroid carcinoma by suppressing the expression of high-mobility group A2, and therefore might provide a promising therapeutic target for patients with papillary thyroid carcinoma.…”
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Potential Health Implications of the Consumption of Thermally-Oxidized Cooking Oils – a Review by Falade Ayodeji Osmund, Oboh Ganiyu, Okoh Anthony Ifeanyi

“…Furthermore, several in vivo studies had suggested that consumption of thermally-oxidized cooking oils might not be healthy as it might negatively influence the lipid profile (increased low density lipoprotein (LDL), decreased high density lipoprotein (HDL) and elevated cholesterol level), haematological system (alteration in concentration of heamoglobin (Hb), packed cell volume (PCV), white blood cell (WBC) count, neutrophil and lymphocyte counts), kidney function, and induce lipid peroxidation and oxidative stress which have been associated with the pathogenesis of various degenerative diseases. …”
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Perceived social support on objective measured sedentary behavior of stroke patients: the mediating role of exercise self-efficacy by Jianing Wei, Fanjiayi Yang, Xiaofang Dong

“…IntroductionAs stroke patients may have impaired motor function, there may have increased sedentary behavior. …”
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Assessment of the State of Cell Membranes against the Background of Prolonged Use of Anticytokine Therapy in Patients with Ulcerative Colitis by E. Yu. Chashkova, N. S. Korotayeva, E. E. Kunetsova, V. G. Gorokhova, E. V. Soboleva

“…Prolonged use of anticytokine therapy with Infliximab for 10 years in patients with ulcerative colitis, upon reaching deep remission, improves endogenous intoxication, restores the structural and functional characteristics of cell membranes, normalizes cell energy metabolism and does not negatively affect the functional state of the kidneys.…”
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Modelling and analysis of selected platform dynamics issues of a land robot by Zbigniew Dziopa, Andrzej Zuska, Dariusz Więckowski

“…Disturbances occurring in the system may negatively affect the measuring and actuating devices mounted on the platform. …”
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Key personal insights and changing needs of osteoarthritis patients: an international quantitative survey analysis by Zoltan Szekanecz, Diana Osadcii-Zaiat, András Bajkó, Hajnalka Minda, Dóra Szerencsés

“…Results Over 60% of respondents reported that poor locomotor function adversely affected their daily activities. …”
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