Gonadal transcriptome analysis reveals MAG participates in ovarian suppression of intersex red claw crayfish (Cherax quadricarinatus) by Honglin Chen, Miaofeng Ouyang, Huan Zhou, Fangfang Liu, Huiyi Cai, Bao Lou

“…The localization of MAG in type I or II cells of androgenic gland revealed its potential function of IAG hormone synthesis. Furthermore, the analyses of gene regulation relationship revealed that IAG positively regulates MAG expression, while MAG negatively regulates vitellogenin gene (VTG) expression. …”
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Odoribacter splanchnicus—A Next-Generation Probiotic Candidate by Jianhong Li, Jing Xu, Xue Guo, Haoming Xu, Chen Huang, Yuqiang Nie, Youlian Zhou

“…Therefore, <i>O. splanchnicus</i> is a strong candidate for “next-generation probiotics”, and its potential probiotic function provides novel ideas for the development of functional foods and the prevention and treatment of metabolic and intestinal inflammatory diseases. …”
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Downregulation of tRNA methyltransferase FTSJ1 by PM2.5 promotes glycolysis and malignancy of NSCLC via facilitating PGK1 expression and translation by Yiling Wang, Yuxin Wen, Qianqian Chen, Yongyi Huang, Duanyang Zhou, Wenhan Yang, Lin Yang, Juan Xiong, Kaiping Gao, Liyuan Sun, Rihong Zhai

“…In human NSCLC tumor samples, FTSJ1 expression was negatively correlated with PGK1 expression level and the SUVmax value of PET/CT scan. …”
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Prolyl‐isomerase Pin1 controls normal and cancer stem cells of the breast by Alessandra Rustighi, Alessandro Zannini, Luca Tiberi, Roberta Sommaggio, Silvano Piazza, Giovanni Sorrentino, Simona Nuzzo, Antonella Tuscano, Vincenzo Eterno, Federica Benvenuti, Libero Santarpia, Iannis Aifantis, Antonio Rosato, Silvio Bicciato, Alberto Zambelli, Giannino Del Sal

“…Mechanistically, following interaction with Pin1, Notch1 and Notch4, key regulators of cell fate, escape from proteasomal degradation by their major ubiquitin‐ligase Fbxw7α. Functionally, we show that Fbxw7α acts as an essential negative regulator of breast CSCs' expansion by restraining Notch activity, but the establishment of a Notch/Pin1 active circuitry opposes this effect, thus promoting breast CSCs self‐renewal, tumor growth and metastasis in vivo. …”
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Clinical outcomes and outcome predictors of two-year assertive community treatment in Norway: an explorative prospective pre–post study by Torleif Ruud, Maria Lie Selle, Hanne K. Clausen, Kristin S. Heiervang, Sigrun Odden, Hanne Kilen Stuen, Anne Landheim

“…Less improvement in functioning was associated with team fidelity and number of sessions. …”
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The contribution of modifiable risk factors to the formation of cardiovascular remodelling and vegetative balance in patients with essential hypertension by V. V. Syvolap, O. V. Vizir-Tronova

“…The presence of any risk factor in EH patients has an unidirectional negative effect on the structural, geometric and functional alteration of the heart, is associated with a tendency to reduce blood flow in all of extra- and intracranial vessels. …”
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Minor Visual Phenomena in Lewy Body Disease: A Systematic Review by Elettra Capogna, Virginia Pollarini, Alessia Quinzi, Lucia Guidi, Luisa Sambati, Maria Sasca Criante, Elena Mengoli, Annalena Venneri, Raffaele Lodi, Caterina Tonon, Micaela Mitolo

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Influence of lifestyle and the circadian clock on reproduction by Masanori Ono, Yidan Dai, Tomoko Fujiwara, Hiroshi Fujiwara, Takiko Daikoku, Hitoshi Ando, Naoaki Kuji, Hirotaka Nishi

“…Circadian rhythm misalignments due to environmental factors, including late‐night work and skipping breakfast, negatively impact endocrine and reproductive functions. …”
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Effects of axylitol-casein complex on insulin resistance and gut microbiota composition in high-fat-diet + streptozotocin-induced type 2 diabetes mellitus mice by Fanhua Kong, Juan Zhang, Shimo Kang, Xinyu Shen, Aicheng Liu, Yan Zheng, Junhua Shao, Xiqing Yue

“…XC decreased body weight and improved glucose tolerance, insulin sensitivity, pancreas impairment, blood lipid levels, and liver function in T2DM mice compared to XY- and CN-treated mice. …”
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Multi-Omics Research Reveals the Effects of the ABA-Regulated Phenylpropanoid Biosynthesis Pathway on the UV-B Response in <i>Rhododendron chrysanthum</i> Pall. by Wang Yu, Xiangru Zhou, Jinhao Meng, Xiaofu Zhou, Hongwei Xu

“…These findings underscore ABA’s crucial function in improving plant resistance to UV-B stress and offer novel insights into plant stress biology.…”
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Neuraminidase Inhibition Primes Short-Term Depression and Suppresses Long-Term Potentiation of Synaptic Transmission in the Rat Hippocampus by Alina Savotchenko, Arthur Romanov, Dmytro Isaev, Oleksandr Maximyuk, Vadym Sydorenko, Gregory L. Holmes, Elena Isaeva

“…Neuraminidase (NEU) is a key enzyme that cleaves negatively charged sialic acid residues from membrane proteins and lipids. …”
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Cuticular protein gene LmACP8 is involved in wing morphogenesis in the migratory locust, Locusta migratoria by Xiao-ming ZHAO, Jia-peng YANG, Xin GOU, Wei-min LIU, Jian-zhen ZHANG

“…Cuticular proteins (CPs) are major components of the insect cuticle-associated organs such as integument and wings, although the importance of CPs for wing development and function in hemimetabolous insects remains understudied. …”
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Introducing an adjustable upper limb prosthesis into a Ugandan clinical service: impacts on free living behaviour and prosthetic use by N. Pickard, B. Mulindwa, L. Gracey-McMinn, M. Granat, A. Chadwell, S. Curtin, D. Howard, L. Ackers, R. Ssekitoleko, L. Kenney

“…Abstract Access to prosthetic services in Uganda is poor, negatively impacting people with upper limb difference in function, community participation, and employment. …”
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Characterization of a new mutation of mitochondrial ND6 gene in hepatocellular carcinoma and its effects on respiratory complex I by Veronica Bazzani, Deepali L Kundnani, Mara Equisoain Redin, Francesca Agostini, Kirti Chhatlani, Angelo Corso Faini, Jakub Poziemski, Umberto Baccarani, Pawel Siedlecki, Silvia Deaglio, Francesca Storici, Carlo Vascotto

“…Through biochemical analyses, we characterized this new mutation and showed that the expression of ΔND6 negatively affects the stability and functionality of Complex I. …”
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Current trends in the pharmacotherapy of uterine myoma, associated with heavy menstrual bleeding and anemia: a literature review by Z. V. Revazova, L. V. Adamyan, O. N. Loginova, L. M. Manukyan, K. N. Arslanyan

“…However, today it is important to apply a personalized approach to the management of a female patient with symptomatic uterine myoma, taking into account her wish to preserve reproductive function. Advances in drug therapy greatly contributed to optimizing management of such patients.Conclusion. …”
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Strain of <i>Xanthomonas oryzae</i> pv. <i>oryzae</i> Loses Virulence through Dysregulation of Cardiolipin Synthase by Yiqun Hu, Qingqing Chen, Aifang Zhang, Liyuan Zhang, Hansong Dong

“…This study aims to further elucidate the underlying bacterial virulent function of trans3287. The expression of trans3287 was quantified in virulence-inducing and standard nutritional conditions to clarify its production mechanism. …”
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A strategy to reduce thermal expansion and achieve higher mechanical properties in iron alloys by Hao Lu, Chang Zhou, Yuzhu Song, Yuanpeng Zhang, Yiming Wu, Feixiang Long, Yonghao Yao, Jiazheng Hao, Yan Chen, Dunji Yu, J. Jakob Schwiedrzik, Ke An, Lunhua He, Zhaoping Lu, Jun Chen

“…Abstract Iron alloys, including steels and magnetic functional materials, are widely used in capital construction, manufacturing, electromagnetic technology, etc. …”
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Green synthesis of agro-waste–derived potassium-doped graphene oxide for antimicrobial activity by Kamal Garwal, Chetna Tewari, Tanuja Arya, Jyoti Rawat, Veena Pande, Souvik Basak, Mayukh Bose, Yong Chae Jung, Nanda Gopal Sahoo

“…Graphene oxide (GO) has been unlocked as a potential bactericidal agent with multifaceted applications for a high degree of abundance of oxidizing functional groups over its structure. The potassium doping of GO (K-GO) enhances its biocompatibility and antimicrobial efficacy. …”
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Radiological markers of CSF α-synuclein aggregation in Parkinson’s disease patients by Amgad Droby, Avital Yoffe-Vasiliev, Daniel Atias, Kyle B. Fraser, Omar S. Mabrouk, Nurit Omer, Anat Bar-Shira, Mali Gana-Weisz, Orly Goldstein, Moran Artzi, Dafna Ben Bashat, Roy N. Alcalay, Avi Orr-Urtreger, Julia C. Shirvan, Jesse M. Cedarbaum, Nir Giladi, Anat Mirelman, Avner Thaler

“…Quantitative measures including striatal binding ratios (SBR), whole-brain and deep gray matter volumes, neuromelanin-MRI (NM-MRI), functional connectivity (FC), and white matter (WM) diffusion-tensor imaging (DTI) were calculated. …”
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Anti-IFN-γ Autoantibody Syndrome Presenting with Disseminated Nontuberculous Mycobacteria Infections: A Case Series of Therapeutic Implications and Review of Literature by Brooke Cheng, Barinder Bajwa, Seungwon Choi, Hannah Martin, Tyson Miao, Denise Werry, Michael Perlman, Yazdan Mirzanejad

“…Anticytokine autoantibodies (AAbs), particularly anti-interferon-gamma (anti-IFN-γ) AAbs, disrupt cytokine functions, leading to infections, autoimmune-like diseases, and conditions resembling interleukin-12 (IL-12)/IFN-γ pathway defects. …”
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