Showing 9,441 - 9,460 results of 12,169 for search 'Negative function', query time: 0.19s Refine Results
  1. 9441

    Impact and effect mechanisms of mass campaigns in resource-constrained health systems: quasi-experimental evidence from polio eradication in Nigeria by Olakunle Alonge, Svea Closser, Marco J Haenssgen

    Published 2021-03-01
    “…The frequency of campaigns was most concentrated in regions with weak health systems, where the operations of RI were disrupted, alongside negative effects on child survival and institutional delivery. …”
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    Article
  2. 9442

    Impact of Human Resource Planning on Organizational Performance in Local Government: A Case Study of Kabale District Local Government. by Natukunda, Promise

    Published 2024
    “…These included extrinsic motivation encourages staff to complete their task in order to receive the reward pay reward system is a product of an organization’s philosophy, employee recognition, training and development programs are strategic functions of human capital management, poor performance reviews due to inadequate job training can produce employee dissatisfaction and conflict and negative attitude, management must see the need to help workers develop skills and build new capacities necessary.…”
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    Thesis
  3. 9443

    Management of Farm Development and Their Role in the Socio-Economic Recovery of Rural Areas by Oleksandr Shpykuliak, Mariana Humeniuk, Diana Shelenko, Dmytro Nemish, Sergiy Balaniuk

    Published 2025-06-01
    “…Farming, in which the capabilities of the family and the farm are harmoniously combined in the development of economic, environmental, social and cultural functions, has the greatest opportunities in ensuring the sustainable development of rural areas, as well as achieving resilience criteria, which makes the study of its development relevant. …”
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    Article
  4. 9444

    Suppression subtractive hybridization identified differentially expressed genes in colorectal cancer: microRNA-451a as a novel colorectal cancer–related gene by Ke Xu, Yuan-Yuan Zhang, Bin Han, Yang Bai, Yao Xiong, Yi Song, Li-Ming Zhou

    Published 2017-04-01
    “…Gene ontology analysis showed that the main functions of these genes were associated with translational elongation, protein localization to the endoplasmic reticulum, translation, poly(A) RNA binding, negative regulations of Wnt signaling pathway, and so on. …”
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    Article
  5. 9445

    Retracted: SLCO4A1‐AS1 promotes cell growth and induces resistance in lung adenocarcinoma by modulating miR‐4701‐5p/NFE2L1 axis to activate WNT pathway by Yuxuan Wei, Li Wei, Jiwei Li, Zeheng Ma, Quan Zhang, Zhijun Han, Saisai Li

    Published 2020-10-01
    “…Abstract Long noncoding RNAs (lncRNAs) possessed essential functions in the biological behaviors of various human cancers. …”
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    Article
  6. 9446

    Biopsychosocial factors and falls among older adults during the COVID-19 pandemic: a longitudinal study by Renata Zacharias Grando, Letícia Pophal Cutisque, Alyssa Cristine de Oliveira Elias, André Luiz Felix Rodacki, Natália Boneti Moreira

    Published 2024-12-01
    “…The variables tested were based on the biopsychosocial approach: diseases and COVID-19 infection (Health Conditions), body mass index, cognition, and depression (Body Functions and Structures), physical activity, sedentary behavior (SB), and functional capacity (Activity), health-related quality of life (HRQoL, Participation), medications (Environmental), falls history and fear of falling (Personal). …”
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    Article
  7. 9447

    RNA‐seq analysis of mitochondria‐related genes regulated by AMPK in the human trophoblast cell line BeWo by Bin Wu, Albert Gao, Bin He, Yun Chen, Xiangfeng Kong, Fayuan Wen, Haijun Gao

    Published 2025-04-01
    “…Abstract Background How AMP activated protein kinase (AMPK) signaling regulates mitochondrial functions and mitophagy in human trophoblast cells remains unclear. …”
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    Article
  8. 9448

    Starch films cross-linked with boronated chitosan enriched with cannabis oil as food packaging material by Kinga Mylkie, Dorota Chełminiak-Dudkiewicz, Dariusz T. Młynarczyk, Aleksander Smolarkiewicz-Wyczachowski, Marta Ziegler-Borowska

    Published 2025-09-01
    “…Starch films containing cannabis oil (3 % w/w) (CBD-S) were further enhanced through crosslinking with chitosan functionalized with boronic acid (Cs-FPBA-CBD-S). Crosslinking starch with boronic acid-functionalized chitosan improved the films' hydrophobicity, significantly reducing the water vapor transmission rate (WVTR) from 5 g/m2·day (for the CBD-S film) to 3 g/m2·day (for the Cs-FPBA-CBD-S films). …”
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    Article
  9. 9449

    Efficacy of low-load blood flow restricted resistance EXercise in patients with Knee osteoarthritis scheduled for total knee replacement (EXKnee): protocol for a multicentre random... by Inger Mechlenburg, Per Aagaard, Stian Langgård Jørgensen, Marie Bagger Bohn

    Published 2020-10-01
    “…Moreover, despite chances of recovering to preoperative functional levels, patients receiving TKR have demonstrated persistent deficits in quadriceps strength and functional performance compared with healthy age-matched adults. …”
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    Article
  10. 9450

    Interactions of rare earth elements with living organisms and emerging biotechnical applications by Samantha A. McGaughey, Shagufta Iqbal, Annamaria De Rosa, Jessica A. Caley, Anna H. Kaksonen, Denys Villa‐Gomez, Caitlin S. Byrt

    Published 2025-09-01
    “…Plants, and some microorganisms, can harness REE properties to enhance their metabolic processes and physiological functions. Exploration and understanding of the mechanisms plants and microbes use to manage REEs can inspire improved processes for extraction and refining towards meeting growing demand for these essential elements while minimizing negative environmental impacts. …”
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    Article
  11. 9451

    Shoulder Pain among Rehabilitated Spinal Cord Injured Persons Using Manually Propelled Wheelchairs in the Gaza Strip: A Survey by Ziad Al Hawamdah, Jadallah M El-Shafie, Khamis El Essi, Sami I Zaqout

    Published 2012-08-01
    “…It also aimed to detect the degree of satisfaction with shoulder functioning wheelchair users who were paraplegic due to  spinal cord injury, in the Gaza strip.…”
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    Article
  12. 9452

    Phage Endolysins as Promising and Effective Candidates for Use Against Uropathogenic <i>Escherichia coli</i> by Wojciech Wesołowski, Aleksandra Łukasiak, Sylwia Bloch, Kaja Kuligowska, Julia Neumann, Natalia Lewandowska, Emilia Węglińska, Grzegorz Węgrzyn, Bożena Nejman-Faleńczyk

    Published 2025-04-01
    “…These proteins exhibit significant variations in sequence length, molecular weight, isoelectric point, and stability, as well as diverse functional domains determining their enzymatic activity, including lysin, lysozyme, hydrolase, amidase, and peptidase functions. …”
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    Article
  13. 9453

    Dissecting the genetic architecture of key agronomic traits in lettuce using a MAGIC population by Hongyun Chen, Jiongjiong Chen, Ruifang Zhai, Dean Lavelle, Yue Jia, Qiwei Tang, Ting Zhu, Menglu Wang, Zedong Geng, Jianzhong Zhu, Hui Feng, Junru An, Jiansheng Liu, Weibo Li, Shenzhao Deng, Wandi Wang, Weiyi Zhang, Xiaoyan Zhang, Guangbao Luo, Xin Wang, Sunil Kumar Sahu, Huan Liu, Richard Michelmore, Wanneng Yang, Tong Wei, Hanhui Kuang

    Published 2025-03-01
    “…The wild-type LsTCP4 gene plays critical roles in leaf flatness and its expression level is negatively correlated with leaf curvature. Additionally, a novel zinc finger protein (ZFP) gene is required for the development of lobed leaves; a point mutation leads to its loss of function and consequently converted lobed leaves to non-lobed leaves, as exhibited by most lettuce cultivars. …”
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    Article
  14. 9454

    Glucose deprivation and identification of TXNIP as an immunometabolic modulator of T cell activation in cancer by Agathe Dubuisson, Adèle Mangelinck, Samantha Knockaert, Adrien Zichi, Etienne Becht, Wendy Philippon, Sandra Dromaint-Catesson, Manon Fasquel, Fabien Melchiore, Nicolas Provost, Dawid Walas, Dawid Walas, Hélène Darville, Jean-Pierre Galizzi, Céline Lefebvre, Véronique Blanc, Vincent Lombardi

    Published 2025-04-01
    “…In cancer, the tumor microenvironment (TME) represents a complex system with a strong metabolism stress, in part due to glucose shortage, which limits proper T cell activation, differentiation and functions preventing anti-tumor immunity.MethodsIn this study, we evaluated T cell immune reactivity in glucose-restricted mixed lymphocyte reaction (MLR), using a comprehensive profiling of soluble factors, multiparametric flow cytometry and single cell RNA sequencing (scRNA-seq).ResultsWe determined that glucose restriction potentiates anti-PD-1 immune responses and identified thioredoxin-interacting protein (TXNIP), a negative regulator of glucose uptake, as a potential immunometabolic modulator of T cell activation. …”
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    Article
  15. 9455

    Synthesis and characterization of tungsten oxide–cerium oxide/chitosan nanocomposites for photocatalytic degradation of methylene blue in sewage water under sunlight by Dhivya Viswanathan, Surya Parthasarathy, Sutha Sadhasivam, Krishna Prakash Arunachalam, Khuloud A. Alibrahim, Abdullah N. Alodhayb, Saravanan Pandiaraj, Rajakumar Govindasamy, Sridevi Balu

    Published 2025-09-01
    “…The crystallographic and functional group analysis of the as-developed nanoparticles was performed through X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR), indicating the presence of the phase-pure nanocomposites with specific functional properties. …”
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    Article
  16. 9456

    Dual Role of Pennisetum purpureum as a Phytogenic Feed Additive: Enhancing Growth and Profitability in Antibiotic-Free Broiler Production by Alvin Lim Teik Zheng, Kelly Kai Seng Wong, Yee Lyn Ong, Jacqueline Lease, Yoshito Andou, Faez Firdaus Abdullah Jesse, Eric Lim Teik Chung

    Published 2025-08-01
    “…Comprehensive characterization was conducted on the raw grass, revealing structural features and functional groups characteristic of bioactive, fibrous biomass. …”
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    Article
  17. 9457

    Analysis of Factors Influencing the Development of Community-Based Tourism in Rural Areas, Case Study: Villages Targeted by Tourism in the Markazi Province by Hamid Afshari, Behrouz Mohammadi Yeganeh, Hossein Farahani, Mehdi Cheraghi

    Published 2024-01-01
    “…This attention of tourists has positive and negative aspects. The positive points have been the increase in tourism tours and the negative effects of the destruction of the rural environment. …”
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    Article
  18. 9458
  19. 9459

    First Principles Calculation Guided Material Selection of Poly(propylenemonothiocarbonate) for High-Performance Triboelectric Nanogenerators by Muhammad Naeem Shah, Jiaqi Lu, Dinku Hazarika, Munir Ullah Khan, Srinivasa Rao Pathipati, Kaihang Zhang, Liangquan Xu, Jie Li, Xiaozhi Wang, Shurong Dong, Jikui Luo

    Published 2025-01-01
    “…However, most developments to increase the power outputs of TENGs have focused on tribo-negative materials, with limited exploration of tribo-positive materials. …”
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    Article
  20. 9460

    Impact of continuous cropping on tobacco growth, stress resistance, and soil microecological structure by Shikang Yu, Huizhan Gu, Jixian He, Fucheng Li, Weijie Liu, Qi Chen, Yu Lai, Bo Zhu

    Published 2024-12-01
    “…High-throughput sequencing technology was used to analyze and predict the microbial community structure and functional gene variation patterns of tobacco soil. …”
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    Article