Clinical Application of 3D‐Printed Custom Hemipelvic Prostheses With Negative Poisson's Ratio Porous Structures in Reconstruction After Resection of Pelvic Malignant Tumors by Xin Hu, Chuang Li, Xiaodi Tang, Yitian Wang, Yi Luo, Yong Zhou, Chongqi Tu, Xiao Yang, Li Min

“…Follow‐up duration was 48 months (range, 29–64 months) Oncological, functional, surgical, pain control, and radiographic outcomes were assessed. …”
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Oxidative stress-induced ZEB1 acetylation drives a hybrid epithelial-mesenchymal phenotype and promotes lung metastasis in triple-negative breast cancer by Min Guo, Yan-Jing Wang, Jie Shi, Li-Xia Cao, Yang Ou, Xiao Jia, Chun-Chun Qi, Zhao-Xian Li, Yu-Xin Liu, Si-Yu Zuo, Qiu-Ying Shuai, Tian-Wen Yu, Hua-Yu Hu, Xiao Chen, Meng-Dan Feng, Yao Xue, Hang Wang, Pei-Qing Sun, Lei Liu, Yi Shi, Shuang Yang

“…Herein, we identified an oxidative stress-responsive CBP/SIRT1 axis that coordinated ZEB1 acetylation at K1108 to promote lung metastasis in triple-negative breast cancer (TNBC). Mechanistically, the biochemical and functional analyses revealed that the dual-acetyltransferase CBP, through stabilization and autoacetylation by oxidative stress, formed a dynamic partnership with SIRT1 to execute precision lysine modification. …”
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Reconstruction of Traumatic Defect of the Lower Third of the Leg Using a Combined Therapy: Negative Pressure Wound Therapy, Acellular Dermal Matrix, and Skin Graft by Sergio Brongo, Domenico Pagliara, Nicola Campitiello, Corrado Rubino

“…We show an easy option to obtain a coverage of traumatic pretibial defects with good aesthetic and functional results: the association of negative pressure wound therapy, acellular dermal matrix, and skin graft. …”
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SLC44A2 negatively regulates mitochondrial fatty acid oxidation to suppress colorectal progression by blocking the MUL1-CPT2 interaction by Ying Yang, Longlong Zheng, Jiaxing He, Tao Wu, Haicheng Yang, Bo Zhang, Shuai Zhou, Yueyue Lu, Xianli He, Jibin Li, Nan Wang

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MARCH8 promotes the proteasomal degradation of foot-and-mouth disease virus VP1, VP2, and VP3 to negatively regulate viral replication by Mengge Yin, Xiangmin Li, Min Zhang, Qiongqiong Zhao, Haoyuan Wang, Huiyan Zhang, Zengjun Lu, Ping Qian

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P72 | A SWAB NEGATIVE PATIENT AFTER SARS-COV-2 INFECTION DISPLAYS INCREASE OF VEGF AND FIBRONECTIN ASSOCIATED WITH ALTERATIONS OF INTERCELLULAR JUNCTIONS

“…The ultrastructural analysis gave insights on the morpho-functional effects of SARS-Cov-2 infection on the gut epithelium, indicating that the damage is not limited to vascular structures. …”
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La construction de l’oubli dans le récit mémoriel : le cas du verbe se rappeler à la forme négative by Nesrine RAISSI

“…Abstract This contribution aims to understand the discursive functioning of the process of forgetting in the testimonies of the internees of the Rivesaltes camp (1941-1942). …”
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Calcitriol Inhibits the Proliferation of Triple-Negative Breast Cancer Cells through a Mechanism Involving the Proinflammatory Cytokines IL-1β and TNF-α by Isela Martínez-Reza, Lorenza Díaz, David Barrera, Mariana Segovia-Mendoza, Sigifredo Pedraza-Sánchez, Giovanny Soca-Chafre, Fernando Larrea, Rocío García-Becerra

“…Triple-negative breast cancer (TNBC) is one of the most aggressive tumors, with poor prognosis and high metastatic capacity. …”
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Identification and characterization of a novel small viral peptide (VSP59) encoded by Bombyx mori cypovirus (BmCPV) that negatively regulates viral replication by Manman Cao, Qunnan Qiu, Xing Zhang, Wenxue Zhang, Zeen Shen, Chang Ma, Min Zhu, Jun Pan, Xingyu Tong, Guangli Cao, Chengliang Gong, Xiaolong Hu

“…In this study, we identified a novel small open reading frame within the S10 dsRNA genome, encoding a small viral peptide (VSP59) with 59 amino acid residues. Functional characterization revealed that VSP59 acts as a negative regulator of viral replication. …”
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Protection of the public in a large-scale radiation accident: mitigation of negative social consequences of protective actions. Part 1. Interpretation of dose characteristics of em... by Yu. O. Konstantinov

“…The protective actions which were carried out with the purpose to reduce public exposure to radiation derived from the accidents at Chernobyl and Fukushima-1 nuclear power plants have caused negative consequences of social – psychological both social-economic character and medical nonradiological consequences. …”
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Circular RNA profiling identifies circ_0001522, circ_0001278, and circ_0001801 as predictors of unfavorable prognosis and drivers of triple-negative breast cancer hallmarks by Dania Awata, Vishnubalaji Radhakrishnan, Hibah Shaath, Ramesh Elango, Sameera Rashid, Mohammed Akhtar, Thasni Karedath Abdul Azis, Ikhlak Ahmed, Khalid Ouararhni, Ammira S. Al-Shabeeb Akil, Nehad M. Alajez

“…The expression of sixteen of these circRNAs was validated in triple-negative breast cancer (TNBC) model using RNase R resistance assay. …”
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Serum LINC01278 serves as a negative biomarker for sepsis and its up-regulation inhibits LPS-induced inflammatory response in THP-1 cells by Ying Gu, Honggang Jia, Xinyu Lin, Ling Wang

“…Dual-luciferase reporter assays, along with RIP experiments, have verified that LINC01278 functions as a competitive endogenous RNA (ceRNA) for miR-451a. …”
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TCF1-positive and TCF1-negative TRM CD8 T cell subsets and cDC1s orchestrate melanoma protection and immunotherapy response by Saraí G De León-Rodríguez, Cristina Aguilar-Flores, Julián A Gajón, Ángel Juárez-Flores, Alejandra Mantilla, Raquel Gerson-Cwilich, José Fabián Martínez-Herrera, Diana Alejandra Villegas-Osorno, Claudia T Gutiérrez-Quiroz, Sergio Buenaventura-Cisneros, Mario Alberto Sánchez-Prieto, Edmundo Castelán-Maldonado, Samuel Rivera Rivera, Ezequiel M Fuentes-Pananá, Laura C Bonifaz

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Integrated proteomics and transcriptomics analysis reveals key regulatory genes between ER-positive/PR-positive and ER-positive/PR-negative breast cancer by Zhengjia Lu, Jiao Yang, Yang Feng, Jia Ming

“…Additionally, there were differences in functional pathway enrichment analysis (galactose_metabolism, glycolysis_gluconeogenesis, jak_stat_signaling_pathway, pentose_phosphate_pathway, et al.) and immune cell infiltration (CD8 T cell, Macrophages M1, et al.) between the high-risk and low-risk groups. …”
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Epistatic relationships reveal the functional organization of yeast transcription factors by Jiashun Zheng, Joris J Benschop, Michael Shales, Patrick Kemmeren, Jack Greenblatt, Gerard Cagney, Frank Holstege, Hao Li, Nevan J Krogan

“…Abstract The regulation of gene expression is, in large part, mediated by interplay between the general transcription factors (GTFs) that function to bring about the expression of many genes and site‐specific DNA‐binding transcription factors (STFs). …”
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Cognitive self-regulation as a predictor of social functioning in schizophrenia by Shivani Santosh, Partha Sarathi Kundu

“…Conclusion: CSR was found to be a highly reliable and valid tool and was able to predict social functioning along with positive and negative symptoms.…”
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CHANGES IN LUNG FUNCTION IN THE TREATMENT OF PATIENTS WITH EXOGENOUS ALLERGIC ALVEOLITIS by V. B. Nefedov, L. A. Popova, E. A. Shergina, N. N. Makaryants

“…Poorer lung function appeared as negative changes in lung volumes and capacities in the patients with acute EAA, as worse pulmonary gas exchange function and negative changes in lung volumes and capacities and deteriorated bronchial patency in those with subacute and chronic EAA.…”
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SELF-STIGMA IMPACT ON SOCIAL FUNCTIONING OF PATIENTS WITH CHRONIC SCHIZOPHRENIA by Amal Gamal Shehata, Enas Mahrous Abd El Aziz

“…Inventory of stigmatizing experiences, social functioning scale, and assessment of severity of negative symptoms scales were used to collect data. …”
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Functional MRI study on anxiety-enhanced temporomandibular joint pain by SUN Yidan, YANG Xin

“…The degree of temporomandibular joint pain aggravated with the stimulation of negative emotional pictures and improved with the neutral pictures. …”
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Subcutaneous adipose tissue-secreted proteins as endocrine regulators of physical and cognitive function in older adults by Cheehoon Ahn, Ian Tamburini, James A. Sanford, Mingqi Zhou, Farah Gamie, Reichelle X. Yeo, Carlos H. Viesi, Maria Pino, Katie L. Whytock, Lauren E. Oberlin, Theresa Mau, Joshua N. Adkins, Jamie N. Justice, Ashlee N. Wood, Zana M. Ross, Paul.D. Piehowski, Chelsea M. Hutchinson Bunch, Kirk I. Erickson, Frederico G.S. Toledo, Nancy E. Lane, Peggy M. Cawthon, Anne B. Newman, Stephen B. Kritchevsky, Steven R. Cummings, Bret H. Goodpaster, Erin E. Kershaw, Marcus M. Seldin, Lauren M. Sparks

“…Declines in skeletal muscle and cognitive function in older adults have been linked to abnormalities in abdominal subcutaneous adipose tissue (ASAT), yet the underlying molecular mediators remain poorly understood. …”
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