Bioinformatics analysis identifies dysregulation of MiR-548F-3p and its hub gene in triple-negative breast cancer by Samira Behroozi, Mahdieh Salimi, Najaf Allahyari Fard

“…Objective(s): Triple-negative breast cancer (TNBC), which affects 15–20% of cases, lacks targeted therapies and poses challenges in treatment. …”
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Camellia sinensis phytochemical profiling, drug-likeness, and antibacterial activity against gram-positive and gram-negative bacteria: in vitro and in silico insights by Farouk Boudou, Amal Belakredar, Ahcene Keziz, Huda Alsaeedi, David Cornu, Mikhael Bechelany, Mikhael Bechelany, Ahmed Barhoum, Ahmed Barhoum

“…Its antibacterial activity was assessed against both Gram-positive (Staphylococcus aureus) and Gram-negative bacteria (Pseudomonas aeruginosa and Escherichia coli). …”
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GROWTH-REGULATING FACTOR 9 negatively regulates arabidopsis leaf growth by controlling ORG3 and restricting cell proliferation in leaf primordia. by Mohammad Amin Omidbakhshfard, Ushio Fujikura, Justyna Jadwiga Olas, Gang-Ping Xue, Salma Balazadeh, Bernd Mueller-Roeber

“…In this study, we focus on the functional characterization of the Arabidopsis thaliana TF GROWTH-REGULATING FACTOR9 (GRF9) and demonstrate that it exerts its negative effect on leaf growth by activating expression of the bZIP TF OBP3-RESPONSIVE GENE 3 (ORG3). …”
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IL-17 A expression negatively correlates with γδ T-Cell density in human psoriasis lesions: a novel implication for disease pathogenesis by Kubra Sevgin, Seyma Ozkanli, Gulam Hekimoglu, Gamze Yesilay, Nurullah Yucel, Halime Tuba Canbaz, Muzaffer Seker

“…Conclusion A weak negative correlation between IL-17 A mRNA levels and γδ T-cell presence in human psoriasis lesions highlighting the novel effector functions of these cells in psoriasis pathogenesis.…”
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Exploring the potential of approved drugs for triple-negative breast cancer treatment by targeting casein kinase 2: Insights from computational studies. by Tagyedeen H Shoaib, Walaa Ibraheem, Mohammed Abdelrahman, Wadah Osman, Asmaa E Sherif, Ahmed Ashour, Sabrin R M Ibrahim, Kholoud F Ghazawi, Samar F Miski, Sara A Almadani, Duaa Fahad ALsiyud, Gamal A Mohamed, Abdulrahim A Alzain

“…Triple-negative breast cancer (TNBC) is an aggressive malignancy that requires effective targeted drug therapy. …”
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Association between the extent of intrapulmonary spread on chest CT and false-negative results of T-SPOT.TB in pulmonary tuberculosis: a retrospective study by Ryo Sato, Naoki Takasaka, Yusuke Hosaka, Taiki Fukuda, Kyota Shinfuku, Makiko Takatsuka, Tsukasa Hasegawa, Masami Yamada, Yumie Yamanaka, Kai Ryu, Takeo Ishikawa, Jun Araya

“…However, clinicians often encounter false-negative T-SPOT.TB results. The extent of TB spread may influence host immune functions, which can influence the results of the T-SPOT.TB test. …”
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Melanophilin inhibit the growth and lymph node metastasis of triple negative breast cancer via the NONO-SPHK1-S1P axis by Xing Yao, Tan Yuen, Chen Qingchuan, Zhang Jianjun, Liu Yefu, Sun Shulan

“…Abstract Background Triple negative breast cancer (TNBC) is the most aggressive breast cancer subtype with the worst prognosis, and there are no targeted treatments available. …”
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Selisistat, a SIRT1 inhibitor, enhances paclitaxel activity in luminal and triple-negative breast cancer: in silico, in vitro, and in vivo studies by Anna Wawruszak, Jarogniew Luszczki, Damian Bartuzi, Joanna Kalafut, Estera Okon, Arkadiusz Czerwonka, Andrzej Stepulak

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Best Practice of Peritoneal Dialysis-Associated Gram-Negative Peritonitis in Children: Insights From the International Pediatric Peritoneal Dialysis Network Registry by Dagmara Borzych-Dużałka, Rebeca Same, Alicia Neu, Hui Kim Yap, Enrico Verrina, Sevcan A. Bakkaloglu, Francisco Cano, Hiren Patel, Maria Szczepańska, Łukasz Obrycki, Ana Paula Spizzirri, Lisa Sartz, Karel Vondrak, Anabella Rebori, Gordana Milosevski-Lomic, Eugene Yu-hin Chan, Biswanath Basu, Andrea Lazcano Pezo, Ariane Zaloszyc, Vimal Chadha, Franz Schaefer, Bradley A. Warady

“…Results: Overall, 74% of episodes responded well to empiric therapy and full functional recovery (FFR) was achieved in 82% of cases. …”
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Estimation of the treatment efficacy in the wounded persons with the gun–shot polystructural damages of upper extremities by S. S. Strafun, N. О. Borzykh N. О. Borzykh, Ya. V. Tsymbaliuk

“…The risk degree for negative impact of the factors on the UE function restoration was estimated.…”
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The molecular prevalence of Theileria equi in the Arabian stallion in Egypt with special reference to biochemical parameters by Noora F. Thabet, Omaima M. Kandil, Omnia M. Kandil, Khalid M. Fararh

“…In the second group, negative T. equi infection (healthy group) (n = 10) and liver and kidney function were detected for both groups. …”
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The correlation between muscle strength, inhibitory function, and cognitive function in older adults with cognitive impairment: evidence from resting-state electroencephalography by Mi Hu, Xing Wang

“…Assessments included the Montreal Cognitive Assessment (MoCA), Stroop task, grip strength, and resting-state EEG.ResultsInhibitory control was significantly related to cognitive function: accuracy in congruent (r = 0.599, p < 0.001) and incongruent (r = 0.474, p < 0.001) conditions correlated positively with MoCA scores, while response times in both conditions showed negative correlations (r = –0.475 and –0.354, respectively, p < 0.001). …”
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Application of visual didactic regulators in distance learning by V. E. Steinberg, R. M. Asadullin, D. R. Fatkhulova, I. R. Tagariyeva

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Altered functional connectivity density in the brains of hemodialysis end-stage renal disease patients: An in vivo resting-state functional MRI study. by Yan Shi, Chaoyang Tong, Minghao Zhang, Xiaoling Gao

“…The purpose of this study was to investigate the changes of global functional connectivity density (gFCD) in brains of ESRD patients undergoing hemodialysis using resting-state functional magnetic resonance imaging (re-fMRI).…”
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Functional analysis of CYP4B1 enzymes from apes and humans uncovers evolutionary hot spots for adaptations of the catalytical function. by Saskia Hüsken, Annika Röder, Johannes Ptok, Anne E Meyer, Mats Georg, Yannick Schwarz, Christian Roos, Kerstin Mätz-Rensing, Michael C Hutter, Doreen M Floss, Allan E Rettie, Marco Girhard, Helmut Hanenberg, Constanze Wiek

“…Systematic functional analyses proved the negative impact of the genetic changes on CYP4B1 activity and showed that reversion of the mutations restored enzyme activity. …”
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Respiratory Function of Fontan Pediatric Patients with Hypoplastic Left Heart Syndrome and Other Morphologies of Functionally Single Ventricle—A Pilot Study by Krzysztof Kocot, Kamil Barański, Daniel Gondko, Olga Smolarek-Kurasz, Jacek Kusa

“…<b>Background/Objectives</b>: Management of complex congenital heart defects with functionally single ventricle remains one of the greatest challenges of pediatric cardiology. …”
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Role of visual function and performance of activities of daily living in cognitive function in patients with mild cognitive impairment: a cross-sectional study by Chunhui Zhou, Ganfeng Yang, Marc Theeboom, Hua Yang, Ruiting Zhu, Zijian Zhou, Dong Zhu

“…Maximum Visual Field (Max VF) was positively correlated with language skills (r = 0.13, p &lt; 0.05). The negative correlation of Minimum Visual Field (Min VF) with cognitive performance became positive after ADL adjustment (β = 0.12, p = 0.04).ConclusionsThese findings suggest that visual function plays a crucial role in the cognitive and functional abilities of patients with MCI. …”
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Effects of Intelligence Levels and Autistic Severity on Adaptive Functioning and Cognitive-Adaptive Functioning Gaps in School-Aged Children with Autism Spectrum Disorder by Jin WY, Song C, Wang YY, Liu XL, Li WH, Wu LL, Zhu ZW

“…Spearman correlation analyses were applied to investigate the associations between intelligence levels, autistic symptoms and adaptive functioning and cognitive-adaptive functioning gaps. …”
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Dung beetle community and functions along a habitat-disturbance gradient in the Amazon: a rapid assessment of ecological functions associated to biodiversity. by Rodrigo F Braga, Vanesca Korasaki, Ellen Andresen, Julio Louzada

“…All response variables were affected negatively by the intensification of habitat disturbance regimes, but community attributes and ecological functions did not follow the same pattern of decline. …”
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Comparing Cognitive Functions and Psychosocial Functioning of Euthymic Patients Having Bipolar Mood Disorder with Healthy Controls: A Cross-sectional Study by Divya Anidharan Rani, Shashwath M. Sathyanath, Ravichandra Karkal, Rohan Dilip Mendonsa, Anil Kakunje

“…The number of episodes (depression/mania) was negatively correlated with psychomotor speed (P = 0.001), verbal working memory/attention (P = 0.049), and visual memory test (P = 0.031), respectively, and positively correlated with time taken for psychomotor functioning of cases (P = 0.001). …”
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