FUNCTIONAL ACTIVITY OF ELDERLY PATIENTS AFTER STROKE by Andriy O. Golyachenko, Igor R. Mysula, Iryna I. Kamyshna, Oleksandr A. Holyachenko

“…This applies to all aspects of a person's life – functional, social, mental, and spiritual. Aim. To perform functional assessment of elderly patients who have suffered a stroke to determine the impact of certain demographic factors and clinical manifestations on daily functioning. …”
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Vegetative growth drives the negative effects of an invasive species on resident community diversity and is not limited by plant–soil feedbacks: A temporal assessment by Emily M. Holden, Karina Salimbayeva, Charlotte Brown, Gisela C. Stotz, James F. Cahill Jr.

“…Though PSFs impacted B. inermis reproduction, they did not sufficiently limit vegetative growth to diminish the negative impacts of B. inermis biomass on native species. …”
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Adverse childhood experiences impair cognitive function via social isolation and functional limitations in Chinese middle-aged and older adults by Yan Zhu, Haojie Yin, Xianli Zhong, Li Wang, Xiaobin Tang, Qin Zhang, Ping Jia

“…In this study, ACEs were positively associated with social isolation and functional limitations (r = 0.081, 0.070, P < 0.01) and negatively associated with cognitive function (r = − 0.132, P < 0.01). …”
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Effectiveness of robot therapy on body function and structure in people with limited upper limb function: A systematic review and meta-analysis. by Fernanda Márcia Rodrigues Martins Ferreira, Maria Emília Abreu Chaves, Vinícius Cunha Oliveira, Adriana Maria Valladão Novais Van Petten, Claysson Bruno Santos Vimieiro

“…In conclusion, RT has small effects on motor control and medium effects on strength in people with limited upper limb function. Poor methodological quality, and lower treatment dose and duration may impact negatively the estimated effects.…”
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FAM96B negatively regulates FOSL1 to modulate the osteogenic differentiation and regeneration of periodontal ligament stem cells via ferroptosis by Qianyi Qin, Haoqing Yang, Runzhi Guo, Yunfei Zheng, Yiping Huang, Luyuan Jin, Zhipeng Fan, Weiran Li

“…Abstract Background Periodontal ligament stem cell (PDLSC)-based therapy is one of the methods to assist bone regeneration. Understanding the functional regulation of PDLSCs and the mechanisms involved is a crucial issue in bone regeneration. …”
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Effects of vitamin D on brain function in preschool children with autism spectrum disorder: a resting-state functional MRI study by Pu Tian, Xiaona Zhu, Zhuohang Liu, Bingyang Bian, Feiyong Jia, Le Dou, Yige Jie, Xuerui Lv, Tianyi Zhao, Dan Li

“…Abstract Background Previous studies indicate vitamin D impacts autism spectrum disorder (ASD), but its relationship with brain function is unclear. This study investigated the association between serum 25-hydroxyvitamin D [25(OH)D] levels and brain function in preschool children with ASD using resting-state functional magnetic resonance imaging (rs-fMRI), and explored correlations with clinical symptoms. …”
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Observation of Brain Functional Connectivity and Activation Characteristics in Children with Attention Deficit and Hyperactivity Disorder Based on Functional Near-Infrared Spectros... by WANG Jing, LIU Yun, HUANG Haoyu, WU Jinting, ZOU Zhuo, CHEN Yingjuan, WEI Xianzhao, SU Hang

“…ObjectiveTo explore the characteristics of functional connectivity in the prefrontal cortex of children with attention deficit hyperactivity disorder (ADHD) at rest and the level of brain functional activation during the Go/No-go task using functional near and infrared spectroscopy (fNIRS).MethodsTwenty-one children with ADHD who visited Kunming Children's Hospital from January 2022 to August 2023 were selected as the study subjects, namely the ADHD group. …”
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Optimizing clinical outcomes: The journey of twins with CRIM-negative infantile-onset Pompe disease on high-dose enzyme replacement therapy and immunomodulation by Angie H. Fares, Ankit K. Desai, Laura E. Case, Cassie Sharon, Amy Klinepeter, Amelia Kirby, Matthew T. Lisi, Rebecca L. Koch, Priya S. Kishnani

“…At 39 months, both twins exhibited normal cardiac function, LVMI, and biomarkers. Motor skills continued to improve, though some kinematic concerns persisted. …”
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Negative regulation of miRNA sorting into EVs is mediated by the capacity of RBP PCBP2 to impair the SYNCRIP-dependent miRNA loading by Francesco Marocco, Sabrina Garbo, Claudia Montaldo, Alessio Colantoni, Luca Quattrocchi, Gioele Gaboardi, Giovanna Sabarese, Carla Cicchini, Mario Lecce, Alessia Carnevale, Rossella Paolini, Gian Gaetano Tartaglia, Cecilia Battistelli, Marco Tripodi

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Neutrophils negatively control IL-17A-producing γδ T cell frequencies in a contact-dependent manner under physiological conditions by Xinhua Yu, Xiaoyang Yue, Xiaoyang Yue, Junie D. Tchudjin Magatsin, Sebastian Marwitz, Sebastian Marwitz, Jochen Behrends, Torsten Goldmann, Torsten Goldmann, Joseph T. Opferman, Brigitte Kasper, Frank Petersen

“…Additionally, in vitro experiments demonstrated that neutrophils could inhibit the function of IL-17A producing γδ T cells by inducing cell death in a contact-dependent manner.ConclusionThis present study demonstrates that neutrophils negatively regulate IL-17 producing γδ T cells under physiological conditions. …”
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Increasing donor kidney age significantly aggravates the negative effect of pretransplant donor-specific anti-HLA antibodies on kidney graft survival by Michiel G. H. Betjes, Judith A. Kal-van Gestel, Dave Roelen, Marcia M. L. Kho, Sebastian Heidt, Annelies E. de Weerd, Jacqueline van de Wetering

“…The preDSA-associated increase in graft failure was caused primarily by an increase in the incidence of antibody-mediated rejection (ABMR), intragraft thrombosis, and primary non-function. These effects were observed more frequently in the deceased donor kidney transplantations compared to living donor kidney transplantations. …”
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Life cycle assessment of an entirely wood floor system designed for carbon negativity, future adaptability, and end-of-life de/re/construction by Muzan Williams Ijeoma, Sovanroth Ou, Amin Nabati, Hao Chen, Michael Stoner, Patricia Layton, Dustin Albright, Brandon Ross, Weichiang Pang, Michael Carbajales-Dale

“…Mass timber offers a promising alternative, with lower embodied carbon (EC) and the potential to function as a carbon sink when sustainably sourced. …”
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Significant associations between high-risk sexual behaviors and enterotypes of gut microbiome in HIV-negative men who have sex with men by Kangjie Li, Xinjing Liu, Xiaohua Zhong, Haijiao Zeng, Tian Liu, Bing Lin, Pinyi Chen, Biao Xie, Xiaoni Zhong

“…Enterotype clusters were determined by Jensen-Shannon divergence based on genus-level relative abundance. Microbial function predictions were conducted by PICRUSt2 software. …”
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Efficacy and safety of cisplatin and paclitaxel (PlaTax regimen) in the neoadjuvant treatment of patients with stage II–III triple-negative breast cancer by O. O. Gordeeva, I. V. Kolyadina, L. G. Zhukova, I. P. Ganshina, G. V. Vyshinskaya, M. A. Kazantseva, M. V. Sukhova, O. E. Ryabishina, E. V. Lubennikova, D. A. Filonenko, E. I. Chichikov, I. N. Polushkina, E. I. Borisova, A. N. Lud, A. A. Meshcheryakov

“…Treatment results for the patients with stage II–III triple negative breast cancer (TN BC) have to be improved. …”
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Legume-based green concentrate alleviates negative energy balance and enhances performance, metabolic health, and profitability in postpartum Holstein Friesian cows by Renny Fatmyah Utamy, Ambo Ako, Zyahrul Ramadan, Yasuyuki Ishii, Mohammad Mijanur Rahman, Kannika Umpuch, Azisah Nurfadilah, Gemal Umar Akmal Alkatiry, Muhammad Akram, Jiant Muthahra Maharani

“…Background and Aim: Negative energy balance (NEB) is a common metabolic disorder in postpartum dairy cows that compromises milk yield, metabolic health, and reproductive function. …”
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Radiation-Based Multi-Modal Therapy Combining with Immunotherapy to Develop a Vaccine-Like Effective Treatment for Triple-Negative Breast Cancer by Dai M, Tian Z, Xu F, Yao B, Liang H, Li D, Wang J, Rong J, Liu T, Tang H, Lu H, Zhang W

“…The synergistic therapy exerts a powerful vaccine-like long-term immune memory function to prevent tumor recurrence with the elevated level of effector memory T (Tem) cells (from 12.8% to 33.3%, P &amp;lt; 0.05).Conclusion: Based on the 4T1 mouse model, developed an effective vaccine-like therapeutic strategy combining X-PDT with Anti-CTLA4, which can effectively ablate tumors, inhibit metastasis, and prevent tumor recurrence. …”
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A domain free of the zeros of the partial theta function by V. Kostov

“…Thus it is an entire function with infinitely-many negative, with no positive and with finitely-many complex conjugate zeros. …”
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Perceptions on causes and effects of common oral diseases among HIV-positive and HIV-negative adults in Kigali, Rwanda: a qualitative study by Julienne Murererehe, Yolanda Malele-Kolisa, Aimable Musafili, Veerasamy Yengopal

“…The summary patterns on perceptions of oral diseases showed more frequency of HIV-positive interviewees reporting physical or functional effect and psychological effects compared to HIV-negative counterparts. …”
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Uncovering a new family of conserved virulence factors that promote the production of host‐damaging outer membrane vesicles in Gram‐negative bacteria by Audrey Goman, Bérengère Ize, Katy Jeannot, Camille Pin, Delphine Payros, Cécile Goursat, Léa Ravon‐Katossky, Kazunori Murase, Camille V. Chagneau, Hélène Revillet, Frédéric Taieb, Sophie Bleves, Laure David, Etienne Meunier, Priscilla Branchu, Eric Oswald

“…It is worth noting that CprA is also a functional ortholog of hemolysin F (HlyF), which is encoded by virulence plasmids of Escherichia coli. …”
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Targeting Reticulin 4 (RTN4) Within Small Extracellular Vesicles Combats Metastasis and Reinforces Immunotherapy in Triple‐Negative Breast Cancer by Han Wang, Renhong Huang, Lei Luo, Ruo Wang, Ziling Zhou, Jin Hong, Jiayi Wu, Ou Huang, Jianrong He, Weiguo Chen, Yafen Li, Xiaosong Chen, Yang Wang, Zheng Wang, Kunwei Shen

“…ABSTRACT Small extracellular vesicles (sEV) are a class of natural vesicles rich in heterogeneous cargos with the great advantage of non‐invasive detection; these vesicles exhibit complex intercellular crosstalk and mediate important biological functions. However, the potential value of plasma sEV in clinical prognosis prediction of triple‐negative breast cancer (TNBC) and their biological functions have not been well elucidated. …”
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