Non-convex optimization with using positive-negative moment estimation and its application for skin cancer recognition with a neural network by P.A. Lyakhov, U.A. Lyakhova, R.I. Abdulkadirov

“…These approaches allow the loss function to more accurately converge in the neighborhood of the global minimum in a smaller number of iterations. …”
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A Dominant-Negative PPARγ Mutant Promotes Cell Cycle Progression and Cell Growth in Vascular Smooth Muscle Cells by Joey Z. Liu, Christopher J. Lyon, Willa A. Hsueh, Ronald E. Law

“…We herein report that a synthetic dominant-negative (DN) PPARγ mutant functions like a growth factor to promote cell cycle progression and cell proliferation in human coronary artery smooth muscle cells (CASMCs). …”
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OsERF2 Acts as a Direct Downstream Target of OsEIL1 to Negatively Regulate Salt Tolerance in Rice by Jiahao Zhou, Shengliang Fang, Xinjie Liu, Lei Luo, Yuhua Liu, Haiwen Zhang

“…Here, we report that OsERF2 is a direct target gene of OsEIL1 and negatively regulates salt tolerance in rice. Compared to the wild type, the gain-of-function mutant of OsERF2 (nsf2857) and the knockdown of OsERF2 via an artificial microRNA (Ami-ERF2) exhibited decreased and increased salt tolerance, respectively. …”
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Antithyroglobulin and Antiperoxidase Antibodies Can Negatively Influence Pregnancy Outcomes by Disturbing the Placentation Process and Triggering an Imbalance in Placental Angiogen... by Kamila Tańska, Piotr Glinicki, Beata Rebizant, Piotr Dudek, Wojciech Zgliczyński, Małgorzata Gietka-Czernel

“…<b>Methods</b>: Fifty-eight hypothyroid women positive for TPOAb/TgAb, thirty-three hypothyroid women negative for TPOAb/TgAb, and thirty-nine healthy controls were enrolled in this study. …”
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USING OF NEGATIVE WOUND PRESSURE THERAPY (NPWT): A CASE SERIES OF WOUND DISRUPTION AS A COMPLICATION OF A CAESAREAN SECTION by Herman Yosef Limpat Wihastyoko, Ellenora Resti Mustikaningrat, Dorothea Respa Kusumaningrat, Gisella Sekar Wruhastanti, Yohana Joni

“…An innovation where the use of VAC, which has a negative pressure function, can stimulate granulation tissue to form and can bind the edges of the  wound so that it can close naturally. …”
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Intermediate filament IFFO1 negatively regulates the migration of lung cancer cells by inhibiting the IQGAP3-Cdc42 interaction by Yuanling Ye, Fan Shen, Maoli Yan, Conghui Zhan, Jiahua Lv, Mengqin Zou, Zhifeng Wang, Shaokai Ning, Yanfei Gao, Jingxian Wu, Wen Li

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Whole exome sequencing identifies FANCM as a susceptibility gene for estrogen-receptor-negative breast cancer in Hispanic/Latina women by Jovia L. Nierenberg, Aaron W. Adamson, Donglei Hu, Scott Huntsman, Carmina Patrick, Min Li, Linda Steele, Shu Tao, Yuan Chun Ding, Barry Tong, Yiwey Shieh, Laura Fejerman, Stephen B. Gruber, Christopher A. Haiman, Esther M. John, Lawrence H. Kushi, Gabriela Torres-Mejía, Charité Ricker, Jeffrey N. Weitzel, Elad Ziv, Susan L. Neuhausen

“…We tested the association of loss of function (LoF) variants with overall, estrogen receptor (ER)-positive, and ER-negative BC risk. …”
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Rasal2 inhibits autophagic-exosomes secretion via regulating Rab27a in triple-negative breast cancer progression by Xuan Wang, Guocui Qi, Kunning Yang, Linlin Ma, Yuansai Kang, Xiaojing Tang, YanTao Han

“…Abstract Background Triple-negative breast cancer (TNBC) is a subtype with the worst prognosis and there is still a lack of effective treatment. …”
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HDAC2‐Mediated METTL3 Delactylation Promotes DNA Damage Repair and Chemotherapy Resistance in Triple‐Negative Breast Cancer by Xiaoniu He, Yuanpei Li, Jian Li, Yu Li, Sijie Chen, Xia Yan, Zhangrong Xie, Jiangfeng Du, Guoan Chen, Jianbo Song, Qi Mei

“…This study not only elucidates the biological function of lactylated METTL3 in tumor cells but also highlights its negative regulatory effect on cisplatin resistance. …”
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Dual-ferroptosis induction-based microneedle patches for enhanced chemodynamic/photothermal combination therapy against triple-negative breast cancer by Yujie Wang, Zhaoyou Chu, Peisan Wang, Tao Li, Yu Jin, Silong Wu, Xiaowei Song, Weinan Zhang, Miaomiao Yang, Zhengbao Zha, Haisheng Qian, Yan Ma

“…Triple-negative breast cancer (TNBC) remains a refractory subtype of breast cancer due to its resistance to various therapeutic strategies. …”
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A novel peptide 66CTG stabilizes Myc proto-oncogene protein to promote triple-negative breast cancer growth by Huichun Liang, Fubing Li, Huan Fang, Wenlong Ren, Zhongmei Zhou, Jiecheng Wang, Jialing Liu, Yongjia Tang, Xue Liu, Yingying Wu, Jing Peng, Chuanyu Yang, Jiayi Chen, Yuting Fei, Yujie Shi, Dewei Jiang, Nu Zhang, Ceshi Chen

“…Abstract Triple-negative breast cancer (TNBC) is the most malignant subtype of breast cancer that lacks reliable targets for diagnosis and therapy. …”
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The relationship between regional homogeneity in resting-state functional magnetic resonance imaging and cognitive function in depressive disorders with migraine by Wensheng Chen, Guojun Xie, Caixia Xu, Jiaquan Liang, Chunguo Zhang

“…This study explores regional homogeneity (ReHo) abnormalities in resting-state functional magnetic resonance imaging (fMRI) and cognitive function in DDWM patients. …”
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A Self‐Assembling LYTAC Mediates CTGF Degradation and Remodels Inflammatory Tumor Microenvironment for Triple‐Negative Breast Cancer Therapy by Jia‐Yi Lin, Ye Wu, Xiao‐Hui Liang, Min Tang, Xin Sun, Sheng‐Xin Lu, Jin‐Mei Jin, Xin Guo, Bei Wang, Hong‐Zhuan Chen, Wei‐Dong Zhang, Xin Luan

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Entire Bivariate Functions of Exponential Type II by A. Bandura, F. Nuray

“…Let $f(z_{1},z_{2})$ be a bivariate entire function and $C$ be a positive constant. If $f(z_{1},z_{2})$ satisfies the following inequality for non-negative integer $M$, for all non-negative integers $k,$ $l$ such that $k+l\in\{0, 1, 2, \ldots, M\}$, for some integer $p\ge 1$ and for all $(z_{1},z_{2})=(r_{1}e^{\mathbf{i}\theta_{1}},r_{2}e^{\mathbf{i}\theta_{2}})$ with $r_1$ and $r_2$ sufficiently large: \begin{gather*}\sum_{i+j=0}^{M}\frac{\left(\int_{0}^{2\pi}\int_{0}^{2\pi}|f^{(i+k,j+l)}(r_{1}e^{\mathbf{i}\theta_{1}},r_{2}e^{\mathbf{i}\theta_{2}})| ^{p}d\theta_{1}d\theta_{2}\right)^{\frac{1}{p}}}{i!…”
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Exploring the Effects of Motor Training with Neurofeedback on Brain Functional Network in Stroke Patients Based on Functional Near-Infrared Spectroscopy by WANG Yanglong, HUO Congcong, SHAO Guangjian, CHEN Tiandi, LI Zengyong

“…During LC-NFT, clustering coefficients of bilateral DLPFC were negatively correlated with FMA-UE and FMA-LE scores (<italic>P</italic>&lt;0.05), whereas no linear correlations were observed during RST or LCT (<italic>P</italic>&gt;0.05).ConclusionMotor training with neurofeedback effectively promotes reorganization of brain functional networks in stroke patients, demonstrating significant clinical value.…”
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TRIM29 upregulation contributes to chemoresistance in triple negative breast cancer via modulating S100P-β-catenin axis by Qitong Wu, Sumit Siddharth, Deepak Verma, Sheetal Parida, Dipali Sharma

“…Tumor-dissociated cells maintain TRIM29 knockout status as well as exhibit similar functional alterations as chemoresistant TNBC cells. …”
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Multi-omics analyses of the heterogenous immune microenvironment in triple-negative breast cancer implicate UQCRFS1 potentiates tumor progression by Yuhui Tang, Aiqi Xu, Zhongbiao Xu, Jindong Xie, Wei Huang, Liulu Zhang, Yitian Chen, Lu Yang, Shasha Du, Kun Wang

“…Abstract Background Triple-negative breast cancer (TNBC) is commonly characterized by high-grade and aggressive features, resulting in an augmented likelihood of distant metastasis and inferior prognosis for patients. …”
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Weekly paclitaxel in escalating doses in a patient with anthracycline-resistant, triple-negative, metastatic breast cancer with severe liver dysfunction by Ajay Gupta

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Modular Protective Materials Neutralizing Toxins (Organophosphorus Compounds and Mycotoxins) and Exhibiting Biocidity to Gram-positive and Gram-negative Bacterial Cells by V. V. Zavyalov, N. V. Zavyalova, V. I. Kholstov, V. A. Kovtun, V. K. Gorelenkov, G. A. Frolov, I. V. Lyagin, N. A. Stepanov, E. N. Efremenko

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Improved Efficacy of Triple‐Negative Breast Cancer Immunotherapy via Hydrogel‐Based Co‐Delivery of CAR‐T Cells and Mitophagy Agonist by Guodong Li, Ruoxin Du, Donghui Wang, Xiangmei Zhang, Lizhuo Wang, Shuangpeng Pu, Xiaoju Li, Shuning Wang, Juliang Zhang, Beichen Liu, Yuan Gao, Huadong Zhao

“…Abstract Leaky and structurally abnormal blood vessels and increased pressure in the tumor interstitium reduce the infiltration of CAR‐T cells in solid tumors, including triple‐negative breast cancer (TNBC). Furthermore, high burden of tumor cells may cause reduction of infiltrating CAR‐T cells and their functional exhaustion. …”
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