Surface lipoprotein sorting by crosstalk between Lpt and Lol pathways in gram-negative bacteria by Qingshan Luo, Chengai Wang, Shuai Qiao, Shan Yu, Lianwan Chen, Seonghoon Kim, Kun Wang, Jiangge Zheng, Yong Zhang, Fan Wu, Xiaoguang Lei, Jizhong Lou, Michael Hennig, Wonpil Im, Long Miao, Min Zhou, Weiwei Bei, Yihua Huang

“…Abstract Lipopolysaccharide (LPS) and lipoprotein, two essential components of the outer membrane (OM) in Gram-negative bacteria, play critical roles in bacterial physiology and pathogenicity. …”
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Integrated analysis of hub genes and intrinsically disordered regions in triple-negative breast cancer by Azhar Iqbal, Faisal Ali, Sulaiman Ali Alharbi, Muhammad Sajid, Saleh Alfarraj, Momina Hussain, Tehmina Siddique, Rakhshanda Mustaq, Fakhra Shafique, Muhammad Sarfaraz Iqbal

“…Triple-negative breast cancer (TNBC) is the most prevalent breast cancer subtype. …”
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SP1 promotes triple-negative breast cancer progression by targeting USP5 by Shi-Yi Wu, Zi-Mei Peng, Feng-Yi Deng, Jin-Yong Xiong, Pu-Ying Luo, Xiao-Jian Han, Zhen Zhang

“…While dysregulated USP5 expression has been observed in various malignancies, its specific functions and mechanisms in TNBC remain poorly understood. …”
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Speech(lessness), Negative Pleasure, and the Sublime Objects of Suburbia in Ben Lerner’s The Topeka School by Nikolai Wansart

“…In a similar way, the incessant and supernumerary presence of suburban objects in the novel functions as a spread the characters continuously have to face. …”
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Detecting Positive and Negative Changes From SAR Images by an Evolutionary Multi-Objective Approach by Shuang Liang, Hao Li, Yun Zhu, Maoguo Gong

“…Then the objective functions are simultaneously optimized by a multi-objective evolutionary algorithm. …”
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Gram‐Negative Bacteria Targeting AIE Photosensitizer for Selective Photodynamic Killing of Vibrio vulnificus by Hao‐Tian Xin, Qiao‐Wen Lin, Simin Sun, Yu‐Ying Wang, Bing Liu, Wen‐Jin Wang, Zong‐Wan Mao, Kang‐Nan Wang

“…In dark conditions, BDTP functions as an antibiotic, inhibiting bacterial proliferation. …”
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The Fusarium verticillioides minichromosome negatively regulates the biosynthesis of carcinogenic fumonisins during maize infection by Guangjun Li, Xinying Gao, Manyu Zhang, Jun Yang, Shi-Hong Zhang, Wensheng Zhao, You-Liang Peng, Vijai Bhadauria

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Mannose and PMI depletion overcomes radiation resistance in HPV-negative head and neck cancer by Tongchuan Wang, Connor Brown, Niamh Doherty, Niall M. Byrne, Rayhanul Islam, Meabh Doherty, Jie Feng, Cancan Yin, Sarah Chambers, Lydia McQuoid, Letitia Mohamed-Smith, Karl T. Butterworth, Emma M. Kerr, Jonathan A. Coulter

“…This study investigates how mannose, a naturally occurring monosaccharide, combined with phosphomannose isomerase (PMI) depletion, enhances the sensitivity of HPV-negative head and neck tumour models to radiation. …”
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PRL2 negatively regulates FcεRI mediated activation of mast cells by Xin Guo, Yunxuan Lei, Yanhua Xu, Xinyue Du, Lin Lin, Yanping Luo, Yebin Xi, Yinshi Guo, Xiaoyin Niu, Zhaojun Wang, Guangjie Chen

“…In this study, we demonstrate that phosphatase of regenerating liver 2 (PRL2) functions as a negative regulator of FcεRI-mediated mast cell activation. …”
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Improvement of Positive and Negative Feedback Power Hardware-in-the-Loop Interfaces Using Smith Predictor by Lucas Braun, Jonathan Mader, Michael Suriyah, Thomas Leibfried

“…Experimental results show a reduction in phase shift by 21.17° and attenuation improvement of 24.3% for V-PCD at a sample time of 100 µs. The SP transfer functions are also derived and integrated into the listed negative feedback IAs, resulting in an increase in the gain margin (GM) from approximately one to three, which significantly enhances system stability. …”
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515 Targeting negative-self-referential processing with transcranial magnetic stimulation: Feasibility studies by Susan Conroy, Ho-Ching (Shawn) Wang, Yu-Chien Wu, Stephen Strakowski, Paul Holtzheimer

“…Methods/Study Population: Four healthy volunteers completed structural and functional MRI (fMRI). fMRI included a trait-adjective task, a negative self-referential processing task known to activate VMPFC, which is known to be abnormal in major depression. …”
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DLAT promotes triple-negative breast cancer progression via YAP1 activation by Diya Liu, Xuehui Wang, Fengyuan Qian, Danrong Ye, Xiaochong Deng, Lin Fang

“…Background Breast cancer (BC) is the most prevalent malignant tumor in women globally. Triple-negative breast cancer (TNBC) represents the most malignant and invasive subtype of BC. …”
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Antibacterial activity of reduced graphene-silver oxide nanocomposite against gram-negative bacteria by Rashi Chaudhary, N.B. Singh, Garima Nagpal, Fredrick K. Saah

“…The emergence of antibiotic-resistant Gram-negative bacteria necessitates the development of novel antibacterial agents. …”
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Double-negative T cells in combination with ursodeoxycholic acid ameliorates immune-mediated cholangitis in mice by Chunpan Zhang, Guangyong Sun, Hua Jin, Yunxiong Wei, Shimeng Zheng, Xiyu Wang, Xinyan Zhao, Dong Zhang, Jidong Jia

“…Our previous study revealed that the number of hepatic double-negative T cells (DNT), which are unique regulatory T cells, was reduced in PBC patients. …”
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Staphylococcus aureus Strains With a Negative Coagulase Tube Test are Associated With Staphylocoagulase Genotypes by Carly L. Botheras, Dieter Bulach, Eugene Athan

“…Staphylocoagulase type X and XI isolates were more likely to test negative in the coagulase tube test despite evidence of an intact functional coa gene. …”
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Chemoresistant tumor cell secretome potentiates immune suppression in triple negative breast cancer by Eleni Skourti, Kotryna Seip, Nadia Mensali, Shakila Jabeen, Siri Juell, Inger Øynebråten, Solveig Pettersen, Olav Engebraaten, Alexandre Corthay, Else Marit Inderberg, Helmut Dolznig, Gunhild Mari Mælandsmo, Eivind Valen Egeland, Lina Prasmickaite

“…Abstract Background Chemotherapy is an integral part of the clinical management of triple negative breast cancer (TNBC), however, development of chemoresistance occurs frequently. …”
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Methods for analyzing the impact of software changes on objective functions and safety functions by A. А. Legkodumov, B. N. Kozeyev, V. V. Belikov, A. V. Korolkov

“…The study analyzes the common methods for analyzing software changes with a description of their positive and negative sides. The possibility of analyzing changes in the control flow of software functions is considered as an alternative to line-by-line comparison of the full volume of source codes. …”
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Classifying schizophrenia using functional MRI and investigating underlying functional phenomena by Yangyang Liu, Bi Wan, Zixuan Liu, Shuaiqi Zhang, Pei Liu, Ningning Ding, Yuxin Wang, Jun Dong, Moiz Kabeer Ahmad, Haisan Zhang

“…Background: Existing studies have revealed functional abnormalities in certain brain regions of patients with schizophrenia (SZ), but the relationships between these abnormalities and their impact on disease progression remain unclear. …”
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Subjective assessment of sensory function and oral function decline in older adults. by Tetsuo Ichikawa, Tomoya Koda, Mio Kitamura, Takahiro Kishimoto, Takashi Matsuda, Takaharu Goto, Masayuki Domichi, Akiko Suganuma, Shinji Fujiwara, Yasuhiko Shirayama, Kazuhiko Kotani, Naoki Sakane

“…The aim of this study was to investigate the relationship between subjective sensory assessment and oral function, to developing health strategies. This study was conducted as part of the Mima-SONGS Study for examining relationships between oral, cognitive, and physical functions, social factors, nutrition, and health, in older adults living in a mountainous region of Japan. …”
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Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant by Patsy R Tomlinson, Rachel G Knox, Olga Perisic, Helen Su, Gemma V Brierley, Roger L Williams, Robert K Semple

“…This attenuation of p110α signalling by a p110δ-activating PIK3R1 variant potentially explains co-incidence of gain-of-function and loss-of-function PIK3R1 phenotypes.…”
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