Investigation of gray matter volume in individuals with heart failure and preserved ejection fraction by Tianyi Yu, Qiuyun Bai, Yiting Guo, Yuchun Yuan

“…It further assesses the correlation between clinical indicators, cardiac function parameters, and gray matter volume (GMV). …”
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HPK1 kinase inhibitor: a sufficient approach to target HPK1 to modulate T cell activation in cancer immunotherapy compared with degraders by Qin Wang, Xinyi Zhu, Jing Li, Sanjia Xu, Ali Wang, Xinwen Zhang, Xingxing Wang, Xiaopeng Cai, Haimei Xing, Ye Liu, Xuesong Liu, Zhiwei Wang, Lai Wang, Lai Wang, Xi Yuan

“…It has been reported that HPK1 negatively regulates the activation of T cells. Several compounds have been developed and tested in clinical trials to target HPK1 for cancer immunotherapy. …”
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Effect of the Nrf2/HO-1 pathway on aluminum-induced liver injury by Xi Wei, Yueling Luo, Dongjie Yuan, Dong Li, Yixi Nong, Biaoliang Wu, Xiaojie Qin

“…Chronic exposure to aluminum (Al) can lead to the accumulation of Al in the liver, which negatively impacts liver structure and function. Oxidative stress is extensively identified as a key contributor to Al toxicity. …”
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The plasticity of gut microbiota contributes to inter-region dietary differences adaptation of ungulates in the Qinghai-Tibet Plateau by Chengbo Liang, Bin Li, Pengfei Song, Haifeng Gu, Feng Jiang, Meng Zhang, Rui Zhang, Tongzuo Zhang

“…Bharals in the Qinghai Lake basin possessed gut microbiotas with a greater capacity to metabolize carbohydrates. And the functional capacity of such functions was positively correlated with the abundance of Polygonaceae in the diet and negatively correlated with the abundance of Rosaceae and Poaceae. …”
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Serum Krebs von den Lungen-6 as a potential biomarker for early diagnosis of silicosis: a case-control study by Qiying Nong, Xuehua Zhu, Lin Zhong, Ying Li, Liang Yao, Zhiming Hu, Shan Wu, Ziping Zou, Cong Li, Zhifang Liu, Kengkeng Chen, Bizhu Zhang, Wei Wei, Yiru Qin, Yongshun Huang, Na Zhao, Lihua Xia

“…The association between lung function and KL-6 levels in silicosis patients was evaluated using partial correlation analysis. …”
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The cerebral blood flow response to neuroactivation is reduced in cognitively normal men with β-amyloid accumulation by Mark Bitsch Vestergaard, Aftab Bakhtiari, Merete Osler, Erik Lykke Mortensen, Ulrich Lindberg, Ian Law, Martin Lauritzen, Krisztina Benedek, Henrik Bo Wiberg Larsson

“…Conclusion We found a correlation between high PiB SUVr and reduced CBF response to neuronal activation, indicating a link between Aβ accumulation and impaired cerebrovascular function. The impairment was not associated with cortical thinning or hypometabolism, suggesting that Aβ accumulation affecting brain vessel function could be a very early pathology leading to neurodegenerative disease.…”
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Black soldier fly larvae oil can partially replace fish oil in the diet of the juvenile mud crab (Scylla paramamosain) by Yuhang Yang, Tingting Zhu, Min Jin, Xiangkai Li, Shichao Xie, Yuhui Cui, Qicun Zhou

“…In summary, the results of the present study demonstrated that the replacement of FO with BSFO at less than 50% (i.e. in-feed BSFO level of 1.5%) did not negatively affect the growth performance of mud crabs, and could improve the antioxidant capacity, immune response, and enhance mitochondrial function.…”
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Biomarker_nlp: A Python Package for Mining Biomarker Information for Targeted Cancer Therapies by Junxia Lin, Yuezheng He, Subha Madhavan, Chul Kim, Simina M. Boca

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Relationship Between Resting-State Functional Magnetic Resonance Imaging and Different Time in Target Glucose Range in Elderly Patients with Type 2 Diabetes Mellitus by Yang P, Liu S, Li L

“…Elderly T2DM patients in the low-TIR group were more susceptible to impaired brain function, which presented mainly as abnormal reduction in and activation of functional activity in some temporal lobes, frontal lobes, and occipital lobes in the resting state, and more significant when glycemic control is poorer.Keywords: type 2 diabetes mellitus, time in range, resting-state functional magnetic resonance imaging, low-frequency fluctuation, fractional low-frequency fluctuation, regional homogeneity…”
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Mediating role of grip strength between depression symptoms and cognitive function: A cross-sectional study among older adults with diabetes in rural areas. by Xueyan Liu, Fangyun Luan, Lijuan Xiao, Yingjuan Cao

“…Depression symptoms were found to be negatively associated with cognitive function. Grip strength was identified as a mediator in this relationship. …”
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Assessment of Serum FABP‐4 Levels in Hypothyroidism Patients: A Comparative Analysis With a Control Group and Their Correlation With Liver Function Tests and Biochemical Factors by Mundher Mohammad Hamzeh Aldulaimi, Afsaneh Shafiei, Somayeh Ghorbani, Fatima Mohammadzadeh, Safoura Khajeniazi

“…Moreover, serum FABP‐4 levels were negatively correlated with age (p = 0.016) and positively correlated with weight (p = 0.044). …”
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Functional Analysis of Zinc Finger Protein Transcription Factor <i>ZmZFP69</i> Under Low-Temperature Stress at Maize Seedling Stage by Si-Nan Li, Yan Sun, Yun-Long Li, Ming-Hao Sun, Shu-Jun Li, Yue Yin, Tao Yu, Xin Li, Quan Cai, Jian-Guo Zhang

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Genome-wide identification and expression profiling of the bZIP gene family in Chrysanthemum indicum and the functional analysis of CibZIP29 under cadmium stress by Shengyan Chen, Yin Zhang, Kaiyuan Zhang, Shuguang Liu, Yujia Yang, Xingnong Xu

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MdDSK2a‐Like‐MdMTA Module Functions in Apple Cold Response via Regulating ROS Detoxification and Cell Wall Deposition by Nan Hou, Jieqiang He, Chana Bao, Fang Zhi, Xiaoxia Shen, Yu Liu, Chaoshuo Li, Tianle Fan, Xinyue Yang, Baohua Chu, Gege Qin, Zeyuan Liu, Chuang Mei, Bin Tan, Jiancan Feng, Fengwang Ma, Mickael Malnoy, Xuewei Li, Qingmei Guan

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Assessment of Clavicular Shortening in Displaced Midshaft Clavicular Fractures Treated by Nonoperative Method, Plating, and Elastic Nailing: Comparative Functional Analysis—A Case... by Makesh Ram Sriraghavan, Poornima Kumararaja, Balakannan Jeyabalan

“…Patients with clavicular length shortening of >2 cm had distinct differences in their clinical outcomes compared to patients with less severe shortening (<1 cm), as it's associated with discomfort or pain, which can negatively impact a patient's quality of life and functional ability. …”
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Enhanced CO₂ Capture Using TiO₂ Nanoparticle-Functionalized Solvent: A Study on Absorption Experiments by Alice Chillè, Nicola Verdone, Mattia Micciancio, Giorgio Vilardi

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fNIRS evidence of abnormal frontotemporal cortex activation and functional connectivity in depressed patients after stroke: neuromodulatory mechanisms from mild to moderate depress... by Shanshan Zhou, Xiaodie Liu, Mengyuan Chen, Wenyi Chen, Yawen Pan, Yinghao Zhi

“…Differences in hemodynamic activity and functional connectivity across six frontotemporal cortex subregions were examined in three patient groups, and their correlations with 17-item Hamilton Depression Rating Scale (HAMD-17) scores were evaluated.ResultsIn terms of brain activation, the moderate-PSD group demonstrated significantly diminished activation in four particular brain regions in comparison to the non-PSD group (p &lt; 0.05): the bilateral medial prefrontal cortex (mPFC), the ipsilateral dorsolateral prefrontal cortex (DLPFC), and the contralateral temporal lobe (TL), and the activation intensity within these regions was negatively associated with HAMD-17 scores (L-mPFC: rs = −0.315, p = 0.018; R-mPFC: r = −0.377, p = 0.004; L-DLPFC: r = −0.323, p = 0.015; R-TL: r = −0.401, p = 0.002). …”
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Associations of sarcopenia status and its components with the risk of developing functional disability in older Chinese adults: evidence from the China health and retirement longit... by Zhang Hao, Lin Haoxiang, Lin Shujun

“…Further prospective studies are needed to clarify the relationship between sarcopenia status and the risk of developing functional disability and to determine whether indicators of the separate sarcopenia components can be used for early warning, screening and identifying functional disability.…”
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Effect of Low Level Laser Therapy with Neuromuscular Training Program on Pain, Function and Muscle Strength in Participants with Knee Osteoarthritis: A Randomised Controlled Trial by D Thaheera, K Kotteeswaran, K Nishitha

“…Aim: To compare the effect of Low Level Laser Therapy (LLLT) with a neuromuscular training programme and an aerobic exercise programme on pain, function, and muscle strength in participants with knee OA. …”
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Serum Osteopontin and Procollagen Type 1 N-Terminal Propeptide Concentrations: Links to Liver Function, Muscle Mass, and Bone Mineral Density in MASLD and Hypertension by Anna F. Sheptulina, Anastasia Yu. Elkina, Elvira M. Mamutova, Yuriy S. Timofeev, Victoria A. Metelskaya, Oxana M. Drapkina

“…Conclusions: These findings in patients with MASLD and HTN suggest an association between serum P1NP levels and SMM, and between OPN levels and spinal BMD, indicating a potential interplay among liver function, muscle mass, and bone health. Furthermore, OPN appeared to be strongly associated with overall metabolic health indicators, such as WC and EFT, whereas P1NP exhibited a stronger association with muscle mass.…”
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