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2621
The mediating role of family adaptability in the relationship between insecure attachment and family functioning in patients with major depression disorder: a cross-sectional study
Published 2025-08-01“…The aim of the present study was to analyze the mediating role of family adaptability (FA) on the relationship between insecure attachment (IA) and family functioning (FF) in patients with major depressive disorder (MDD), which currently remains unclear. …”
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2622
Body mass index, waist circumference, hip circumference, abdominal volume index, and cognitive function in older Chinese people: a nationwide study
Published 2024-11-01“…Abstract Background Numerous studies have indicated an obesity paradox in observational research on aging health, where being normal weight or underweight adversely affects cognitive function, while moderate obesity may offer protective benefits. …”
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2623
USC-Derived Small Extracellular Vesicles-Functionalized Scaffolds Promote Scarless Vaginal Defect Repair via Delivery of Decorin and DUSP3 Proteins
Published 2025-02-01“…Small extracellular vesicles (sEVs) encapsulate diverse bioactive components, making them potential therapeutic agents. Designing functional scaffolds that incorporate sEVs is a promising approach for scarless vaginal defect repair.Methods: sEVs-loaded scaffolds were developed through electrostatic interactions between negatively charged sEVs secreted by urine-derived stem cells (USC-sEVs) and positively charged human acellular amniotic membranes. …”
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2624
Toxoplasma gondii seropositivity and cognitive functioning in older adults: an analysis of cross-sectional data of the National Health and Nutrition Examination Survey 2011–2014
Published 2024-03-01“…Adjusted linear regression showed that compared with participants with negative Toxoplasma gondii infection, those with positive Toxoplasma gondii infection had lower CERAD-WL immediate memory (beta (β) −0.16, 95% CI −0.25 to –0.07), CERAD-WL delayed memory (β −0.15, 95% CI −0.24 to –0.06), AFT (β −0.15, 95% CI −0.24 to –0.06), DSST (β −0.34, 95% CI −0.43 to –0.26), and global cognition (β −0.24, 95% CI −0.32 to –0.16) z-scores after controlling for the covariates.Conclusions Toxoplasma gondii seropositivity is associated with worse immediate and delayed verbal learning, language proficiency, executive functioning, processing speed, sustained attention, working memory, as well as global cognition in older adults. …”
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2625
Akkermansia muciniphila upregulates genes involved in maintaining the intestinal barrier function via ADP-heptose-dependent activation of the ALPK1/TIFA pathway
Published 2022-12-01“…Finally, we show that A. muciniphila induces the expression of the MUC2, BIRC3 and TNFAIP3 genes involved in the maintenance of the intestinal barrier function and that this process is dependent on TIFA. …”
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2626
Assessing the Success of Ferula assa-foetida L. Plantation Restoration Operations in Semi-Steppe Rangelands by Linking Plant Functional Traits to Species Diversity
Published 2024-05-01“…By studying the dynamics of plant communities, we can understand how the structure, composition, and function of plant communities respond to restoration operations. …”
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2627
Predicting postoperative motor outcomes in the surgical management of Rolandic focal cortical dysplasia: the role of glucose metabolism
Published 2025-07-01“…Of these, 15 patients underwent task-based functional magnetic resonance imaging (fMRI). Motor functional reorganization and its relationship with PET metabolism were analyzed. …”
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2629
Genome-wide characterization of monoacylglycerol lipase (MAGL) gene family in soybean and functional analysis of GmMAGLs in storage lipid metabolism and drought resistance
Published 2025-07-01“…GmMAGL10 and 14 may impact seed oil content negatively while GmMAGL3 function importantly in seed germination. …”
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2630
The muscle ankyrin repeat proteins CARP, Ankrd2, and DARP are not essential for normal cardiac development and function at basal conditions and in response to pressure overload.
Published 2014-01-01“…Together with their strong induction during cardiac disease and the identification of causative Ankrd1 gene mutations in cardiomyopathy patients, this suggests their important roles in cardiac development, function, and disease. To determine the functional role of MARPs in vivo, we studied knockout (KO) mice of each of the three family members. …”
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2631
Assessment of left and right ventricular diastolic and systolic functions using two-dimensional speckle-tracking echocardiography in patients with coronary slow-flow phenomenon.
Published 2015-01-01“…<h4>Conclusions</h4>LV diastolic and systolic functions were impaired in patients with CSFP. CSFP also affected RV diastolic function, but not RV systolic function.…”
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2632
Correlation of soluble triggering receptor expressed on myeloid cells-1 in cerebrospinal fluid with Alzheimer’s disease biomarkers and cognitive function in non-dementia individual...
Published 2025-04-01“…A multiple linear regression analysis was used to investigate the linear correlation between sTREM-1 in CSF and core AD biomarkers and cognitive function, and the mediation analysis was used to explore whether the core AD biomarkers in CSF mediated the association between sTREM-1 and cognitive function. …”
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2633
Longitudinal analysis of coal workers’ pneumoconiosis using enhanced resolution-computed tomography images: unveiling patterns in lung structure, function, and clinical correlation...
Published 2025-05-01“…ADI, SRI, and J were associated with structural deformation, airway remodeling, and parenchymal loss, linking these changes to lung function decline.ConclusionqCT imaging and registration metrics effectively monitor structural and functional lung changes in pneumoconiosis. …”
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2634
A Preliminary Investigation into the Use of Cannabis Suppositories and Online Mindful Compassion for Improving Sexual Function Among Women Following Gynaecological Cancer Treatment
Published 2024-12-01“…Measurements of sexual function, sexual self-efficacy, mindful compassion, well-being and quality of life were taken at weeks 0, 4 and 12. …”
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2635
Early maladaptive schemas, coping strategies, and functional impairments in individuals with adjustment disorder during compulsory military service: a comparison with healthy contr...
Published 2025-07-01“…Maladaptive schemas were negatively correlated with adaptive coping (r = –.389 to –.565) and positively associated with avoidance and functional impairment (r = .573 to.734, p <.01).ConclusionsOur findings suggest that maladaptive schemas may play a key role in how individuals with AD cope with stress, often leading to avoidance behaviors and functional decline. …”
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2636
Identification of PIF Gene Family and Functional Study of <i>PbPIF3a/PbPIF4</i> in Anthocyanin Biosynthesis of Pear
Published 2025-04-01“…Subcellular localization confirmed nuclear enrichment of <i>PbPIF3a</i> and <i>PbPIF4</i>. Functional studies demonstrated that overexpression of <i>PbPIF3a</i> and <i>PbPIF4</i> significantly suppressed anthocyanin accumulation in fruit skins, downregulating key biosynthetic genes such as <i>PbDFR</i> and <i>PbUFGT</i>. …”
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Isolation and Identification of Eurotium cristatum from Different Dark Tea Sources and the Effect of Solid-state Fermentation on the Nutritional and Functional Components of Tartar...
Published 2025-06-01“…Correlation analysis showed that the content of total flavonoids and polyphenols in fermented tartary buckwheat were significantly positively correlated with the activities of phenylalanine ammonia lyase and polyphenol oxidase (P<0.001), respectively, while the contents of reducing sugars were significantly negatively correlated with total starch (P<0.001). These resultsed suggest that the changes in nutritional and functional components in the fermented tartary buckwheat were closely related to the biotransformation by Eurotium cristatum. …”
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2639
25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 exert distinct effects on human skeletal muscle function and gene expression.
Published 2017-01-01“…Age-associated decline in muscle function represents a significant public health burden. …”
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2640
Inclusion of sorghum (Sorghum bicolor (L). Moench) with protease and NSP-ase increases jejunal histomorphology and barrier function gene expression in broiler chickens
Published 2024-12-01“…ABSTRACT: The objective of this study was to investigate the effect of sorghum with or without protease and NSP-ase on performance, jejunal histomorphology, caecal short-chain fatty acids (SCFA), and gene expression of barrier function in the broiler chickens. A total of 240 males New Lohmann strain MB 202 broiler chicks (1-day-old) were randomly placed into 12 treatments with 4 replications, 5 birds per replicate for 35 d. …”
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