Advanced bioprinting strategies for fabrication of biomimetic tissues and organs by Wei Long Ng, Cian Vyas, Boyang Huang, Wai Yee Yeong, Paulo Bartolo

“…Bioprinting is a revolutionary technology within the field of tissue engineering that enables the precise fabrication of three-dimensional (3D) tissue constructs. It combines the principles of engineering and biology to create structures that closely mimic the complexity of native human tissues, facilitating advancements in regenerative medicine and personalized healthcare. …”
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Generation of healthy bovine ovarian organoids: a proof-of-concept derivation technique by María Gómez-Álvarez, Marcos Agustina-Hernández, Emilio Francés-Herrero, Clara Bueno-Fernandez, Paula Alonso-Frías, Nadaya Corpas, Amparo Faus, Antonio Pellicer, Irene Cervelló

“…Abstract Background Organoids have emerged as powerful tools in reproductive medicine and bioengineering, offering three-dimensional (3D) models that closely mimic native tissues. …”
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Protective Effect of Lithium Chloride on EndotheliaL Cells in Septic Shock by O. A. Grebenchikov, V. T. Dolgikh, M. D. Prokofiev, I. S. Kasatkina, A. V. Ershov

“…Toxic serum significantly inhibited GSK-3/3 phosphorylation, induced cleavage of VE-cadherin and reduced the claudin inendothelial cells. …”
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Development of an iridium complex fluorescent probe for FGF21 protein labeling and tracking by Lili Zhang, Shaobo Du, Wangye Ji, Jianfei Li, Ruilin Ma, Dexiang Yan, Yuhao Niu, Shuqin Zhao, Jiaxi Ru, Yuan Gao

“…In this study, a non-emissive cyclometalated Ir(III) solvent complex IrCN was synthesized for FGF21 protein labeling. …”
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CBD-conjugated BMP-inhibiting exosomes on collagen scaffold dual-target Achilles tendon repair: Synergistic regeneration and heterotopic ossification prevention by Yan Xu, Jiaqiang Huang, Yingjie Mai, Zhiyuan Zhang, Siqi Li, Haofeng Lin, Fuxin Wei, Yang Chen

“…At 12 weeks, the 3D-CBD@LDN/Exos group exhibited near-normal histology, enhanced collagen and sGAG deposition, biomechanical properties comparable to native tendons, and significantly reduced HO, indicating that this dual-targeted strategy holds promise for tendon repair.…”
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Ruta montana L. from Morocco: comprehensive phytochemical analysis and exploration of its antioxidant, antimicrobial, anti-inflammatory and analgesic properties by Mohamed El Ouardi, Mohamed El Ouardi, Aziz Drioiche, Aziz Drioiche, Imane Tagnaout, Aicha Benouahi, Aicha Benouahi, Omkulthom AL kamaly, Abdelaaty Abdelaziz Shahat, El Makhoukhi Fadoua, El Makhoukhi Fadoua, Handaq Nadia, Sevser Sahpaz, Touriya Zair, Mohamed Alaoui Belghiti

“…Ruta montana L., a medicinal plant native to Morocco's Middle Atlas region, has been traditionally used for its therapeutic properties. …”
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CircRNA hsa_circ_0004781 promoted cell proliferation by acting as a sponge for miR-9-5p and miR-338-3p and upregulating KLF5 and ADAM17 expression in pancreatic ductal adenocarcino... by Kun-Lin Lee, Jun-Jen Liu, Wei-Jan Huang, Ching-Sheng Hung, Yu-Chih Liang

“…Hsa_circ_0004781 was identified as a sponge for miR-9-5p and miR-338-3p, and its expression was negatively correlated with that of these miRNAs. …”
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Safety evaluation of the food enzyme mucorpepsin from the non‐genetically modified Rhizomucor miehei strain LP‐N836 by EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Lieve Herman, Yrjö Roos, Jaime Aguilera, Magdalena Andryszkiewicz, Cristina Fernàndez‐Fraguas, Natalia Kovalkovicova, Yi Liu, Simone Lunardi, Giulio diPiazza, Andrew Chesson

“…The native enzyme can be chemically modified to produce a more thermolabile form. …”
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High posterior tibial slope increases anterior cruciate ligament elongation in unicompartmental knee arthroplasty during early-flexion of lunge by Nan Zheng, Chunjie Xia, Huiyong Dai, Diyang Zou, Yubin Long, Zhiyong Hou, Qi Wang, Tsung-Yuan Tsai

“…There was a positive correlation between PTS and ACL elongation difference for both FB and MB UKA, indicating excessive PTS should be avoided to preserve native ACL function in further UKA implantation. Levels of Evidence III.…”
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Evaluation of Bioengineered Scaffolds for Mandibular Defect Reconstruction: A Clinical Study by Prasanth Panicker, Feby Francis, Mandapathi S. Kumar, Rajana M. Kumar

“…The scaffolds were customized for each defect using 3D printing technology. Clinical and radiographic assessments were performed at 1, 3, 6, and 12 months postoperatively, evaluating parameters such as defect closure, bone regeneration, and functional restoration. …”
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Efficient Incorporation of DOPA into Proteins Free from Competition with Endogenous Translation Termination Machinery by Youhui Yang, Yingchen Wang, Zhaoguan Wang, Hao Qi

“…3,4-Dihydroxy-L-phenylalanine (DOPA) is a promising noncanonical amino acid (ncAA) that introduces novel catechol chemical features into proteins, expanding their functional potential. …”
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Accurate size-based protein localization from cryo-ET tomograms by Weisheng Jin, Ye Zhou, Alberto Bartesaghi

“…Cryo-electron tomography (cryo-ET) combined with sub-tomogram averaging (STA) allows the determination of protein structures imaged within the native context of the cell at near-atomic resolution. …”
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Multimodal AI and Large Language Models for Orthopantomography Radiology Report Generation and Q&A by Chirath Dasanayaka, Kanishka Dandeniya, Maheshi B. Dissanayake, Chandira Gunasena, Ruwan Jayasinghe

“…The proposed system primarily consists of a Blip-2-based caption generator tuned on DPT images followed by a Llama 3 8B based LLM for radiology report generation. …”
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Problems of the Current Vaccination Strategy against Hepatitis B by M. V. Konopleva, V. N. Borisova, T. A. Semenenko, M. A. Krymskij

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The Link Between Perception and Production in the Laryngeal Processes of Multilingual Speakers by Zsuzsanna Bárkányi, Zoltán G. Kiss

“…Fourteen L1 Hungarian, L2 English, and L3 Spanish advanced learners took part in the experiments. …”
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Emotional social screening tool for school readiness – Revised: IsiXhosa adaptation by Erica Munnik, Prenita Reddi, Mario R. Smith

“…Background: The need for the adaptation of instruments to other native languages to promote culture-fairness framed this study. …”
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Cytotoxic activity of Ganoderma weberianum-sichuanese isolated from the Lower Volta River Basin of Ghana against human prostate carcinoma (PC-3), leukemic T cell (Jurkat), and plas... by Gideon Adotey, Raphael N Alolga, Abraham Quarcoo, Mohammed Ahmed Gedel, Paul Yerenkyi, Phyllis Otu, Abraham K Anang, Laud K N Okine, Winfred S K Gbewonyo, John C Holliday, Vincent C Lombardi

“…Fractions of the mycelial biomass were found to inhibit significantly (≤ 0.05%) the proliferation and survival of the three cancer cell lines, PC-3, PMDC05, and Jurkat with increasing concentrations and with IC50 values of 27.73 ± 5.25, 21.31 ± 2.40 and 17.09 ± 0.86 μg/mL, respectively compared to Chang liver cells (CVCL_0238) with IC50 value of 75.41 ± 1.95 μg/mL. …”
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Phylogenetic analysis of Steinernema pakistanense from the semi-arid regions of India and its toxicity assessment against lepidopteran and coleopteran insects by Ayushi Chaudhary, Parul Chauhan, Ashish Kumar Singh, Istkhar Rao

“…Genetic analysis using ITS and D2-D3 rDNA regions confirmed a high degree of similarity (99.73–100% for ITS and 99.76–99.88% for D2–D3) to S. pakistanense, validating their species identity. …”
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Thermal stability and digestibility of a biopolymer system for the delivery of minor nutrients in enriched meat products by M. G. Semenova, M. A. Aslanova, A. R. Galimova, L. V. Fedulova, A. S. Antipova, E. I. Martirosova, D. V. Zelikina, A. L. Bero, D. A. Utyanov

“…The study examined thermal stability and digestibility of a biopolymer delivery system for the liposomal form of minor nutrients (omega-3 polyunsaturated fatty acids, vitamin D3, essential oil of clove buds) in enriched meat products. …”
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Comprehensive characterization and valorization potential of Amazonian Sacha inchi (Plukenetia volubilis L.) seeds, oil, and oilcake by-products for sustainable food applications by Fernando E. Alejandro Ruiz, Julio F. Ortega Jácome, José R. Mora, Andrea C. Landázuri, Andrea C. Landázuri, Andrea C. Landázuri, Andrea C. Landázuri, Paola Vásconez Duchicela, Julio Vásconez Espinoza, Pablo Beltrán-Ayala, María J. Andrade-Cuvi, José M. Alvarez-Suarez, José M. Alvarez-Suarez

“…BackgroundSacha inchi (Plukenetia volubilis L.), a native oilseed from the Amazon region, has attracted increasing attention for its nutritional richness and potential applications in functional foods. …”
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