Bioanalytical method development for monoclonal antibodies: advances and challenges by Sudha Kallam, Anoop Bodapati, Alapati Reddy, Konatham Reddy

Get full text

Recognising the Fourth Nature: A Case Study of Spontaneous Urban Vegetation in Southwest Australian Cities by Katherine Stewart, Maria Ignatieva

Get full text

Trophic Structure and Isotopic Niche of Invaded Benthic Communities on Tropical Rocky Shores by Larissa M. Pires-Teixeira, Vinicius Neres-Lima, Plínio C. Barbosa, Joel C. Creed

Get full text

First Trial of a Novel Caseous Lymphadenitis Inactivated Vaccine in South Korea: Experimental Evaluation across Various Animal Models by Gyeong-Seo Park, Somin Lee, Min A Jeong, So Young Lee, Dong-Geun Cho, WonIl Cho, Seung-Chai Kim, Hwan-Ju Kim, Taek Geun Lee, Chang-Gi Jeong, Won-Il Kim, Yeonsu Oh, Ho-Seong Cho, Byoung-Joo Seo, Chonghan Kim

Get full text

The Novels Of Syed Muhammad Ashraf and Ecological Discourse by Muhammad Yousuf

Get full text

DIGITALIZATION IN UNIVERSITY EDUCATION: DIDACTIC ASPECTS by Mariia A. Abysova, Mariia H. Kravchuk, Oksana M. Hurniak

Get full text

Problem of People’s Sobriety in the 3^rd State Duma (1907-1912) by I. A. Shevchenko

“…The article is devoted to the problem of developing in the Russian Empire State Duma of the 3rd convocation (1907-1912) a set of anti-alcohol measures, which mainly concerned the peasant population of the country. …”
Get full text

Tunable Alginate-Polyvinyl Alcohol Bioinks for 3D Printing in Cartilage Tissue Engineering by Alexandra Hunter Aitchison, Nicholas B. Allen, Kishen Mitra, Bijan Abar, Conor N. O’Neill, Kian Bagheri, Albert T. Anastasio, Samuel B. Adams

“…This study investigates 3D extrusion bioinks for cartilage tissue engineering by characterizing the physical properties of 3D-printed scaffolds containing varying alginate and polyvinyl alcohol (PVA) concentrations. …”
Get full text

Measuring metalinguistic awareness among heritage speakers in the US-based L3 context by Elisa Fiorenza, Will Travers

“…Researchers further suggest that it helps bilinguals learning a third language (L3) even more than it does monolinguals learning their second language (L2). …”
Get full text

Enhanced thermal dissipation for BCB-bonded 3D integrated membrane photonic circuits by Salim Abdi, Kevin Williams, Yuqing Jiao

“…This thermal resistance is maintained across various BCB thicknesses up to 30 µ m, ensuring the possibility of using such devices for scalable 3D integration on other platforms or with electronics. …”
Get full text

Immunogenic potential and neutralizing ability of a heterologous version of the most abundant three-finger toxin from the coral snake Micrurus mipartitus by Luz Elena Romero Giraldo, Sergio Pulido, Mario Andrés Berrío, María Fernanda Flórez, Paola Rey-Suárez, Vitelbina Núñez-Rangel, Mónica Saldarriaga Córdoba, Jaime Andrés Pereañez

“…Its venom is mainly composed of three-finger toxins (3FTxs), Mipartoxin-1 being the most abundant protein partially responsible for its lethal effect. …”
Get full text

A promising breakthrough in pancreatic cancer research: The potential of spheroids as 3D models by Nazanin Jamshidi, Negar Jamshidi, Amir Modarresi Chahardehi, Elahe Shams, Vahid Chaleshi

“…The inadequacies of two-dimensional (2D) models prompted the exploration of three-dimensional (3D) culture systems, which more faithfully recapitulate the native tumor microenvironment. …”
Get full text

Allergenic Characterization of New Mutant Forms of Pru p 3 as New Immunotherapy Vaccines by C. Gómez-Casado, M. Garrido-Arandia, P. Gamboa, N. Blanca-López, G. Canto, J. Varela, J. Cuesta-Herranz, L. F. Pacios, A. Díaz-Perales, L. Tordesillas

“…However, Pru p 3.02 and Pru p 3.03 presented reduced IgE binding with respect to the native form, by in vitro, ex vivo, and in vivo assays. …”
Get full text

NLRP3 deficiency abrogates silica-induced neutrophil infiltration, pulmonary damage and fibrosis by Maggie Lam, Kristian T. Barry, Christopher J. Hodges, Christopher M. Harpur, James D. H. Ong, Sarah Rosli, Alison C. West, Lovisa Dousha, Paul J. Hertzog, Ashley Mansell, Michelle D. Tate

“…A reporter mouse placed under the native NLRP3 promoter revealed silica rapidly upregulated NLRP3 expression throughout the lung. …”
Get full text

New approaches in 3D modeling of in vitro growth of primary cultures of malignant gliomas by Yu. A. Khochenkova, I. G. Dyrda, Yu. S. Machkova, E. Sh. Solomko, T. A. Sidorova, D. A. Khochenkov, E. A. Avilova

“…Existing cell lines and cultivation methods do not reflect all the features of the three-dimensional (3D) organization of native glioblastoma. …”
Get full text

Highly expressed of SERPINA3 indicated poor prognosis and involved in immune suppression in glioma by Qing Yuan, Song‐Quan Wang, Guang‐Tao Zhang, Jie He, Zhi‐Dan Liu, Ming‐Rong Wang, Hong‐Qing Cai, Jing‐Hai Wan

“…Immune infiltration analysis further declare the SERPINA3 expression negatively correlated with levels of Macrophages M1, native CD4+ T cell, monocytes, and Mast cell activated. …”
Get full text

Pathogenic KIAA0586/TALPID3 variants are associated with defects in primary and motile cilia by Jacqueline E. Taudien, Diana Bracht, Heike Olbrich, Sebastian Swirski, Fulvio D’Abrusco, Bert Van der Zwaag, Maike Möller, Thomas Lücke, Norbert Teig, Ulrika Lindberg, Kai Wohlgemuth, Julia Wallmeier, Anja Blanque, Christos Gatsogiannis, Sebastian George, Christoph Jüschke, Marta Owczarek-Lipska, Dorothee Veer, Hester Y. Kroes, Enza Maria Valente, G. Christoph Korenke, Heymut Omran, John Neidhardt

“…DNA variants were detected in three families by sequencing. In two unrelated families, a deep-intronic variant (KIAA0586/TALPID3:c.3990 + 3186G>A) activated a cryptic exon. …”
Get full text

The ecological niche and population history shape mosquito population genetics on a group of three Caribbean islands by Pepijn Helleman, Maarten Schrama, Krijn B. Trimbos, Marieta A. H. Braks, Francis Schaffner, Arjan Stroo, Roel M. Wouters, Jordy G. van der Beek

“…Results Both the genetic diversity and population genetic structure were found to differ strongly between sets of species, leading to a subdivision into three species groups: (1) non-native species with low genetic diversity across all three investigated islands, (2) locally native species with high genetic diversity and closely related haplotypes occurring on different islands and (3) locally native species with high genetic diversity and locally restricted haplotypes. …”
Get full text

Synthesis and crystal structure of 4-(difluoromethyl)-1-methyl-N-(pyridin-3-yl)-1H-pyrazole-3-carboxamide hydrate, C11H12F2N4O2 by Huang Hao-Wen, Liu Hao-Hong, Lin Si-Tong, Gan Xian-Nv, Zhang Ji

Get full text

A bio-inspired screwed small-diameter vascular graft for endotheliazation and arterial regeneration by Qi Huang, Ke Hu, Chao Xu, Yixia Chen, Linlin Guo, Yuqi Liu, Lixing Bian, Chunlin Wen, Weici Wang, Weilin Xu, Hongjun Yang

“…By three months after implantation, both the endothelial and smooth muscle layers are regenerated, developing hierarchical microstructures and compositions similar to those of native vessels. …”
Get full text