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Potential Mediating Role of Polygenic Hazard Score in the Association Between Neurofilament Light Chain and Default Mode Network Connectivity Across the Alzheimer's Disease Continu...
Published 2025-06-01“…Conclusion: These findings suggest that elevated plasma NfL levels are associated with disrupted ventral DMN connectivity in AD, reflecting neurodegeneration-related network dysfunction. …”
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Multi-pathway blood biomarkers to target and monitor multidimensional prevention of cognitive and functional decline (nested in the IN-TeMPO study framed within the world-wide FING...
Published 2025-05-01“…To date, multidimensional approaches seem to be effective in reducing or delaying the onset of age-related diseases.ObjectivesThe multicentric randomized controlled trial IN-TeMPO (ItaliaN study with Tailored Multidomain interventions to Prevent functional and cognitive decline in community-dwelling Older adults, ClinicalTrials.gov ID NCT06248723), framed within the World-Wide FINGERS network, aims to verify the efficacy of guided multidomain interventions in preventing age-related cognitive and functional decline. …”
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A Team-Compatibility Decision Support System for the National Football League
Published 2020-07-01Get full text
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Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer’s disease
Published 2024-11-01“…However, after symptom onset the rate of change in CSF NfL continued to increase steadily, whereas the rate of change in plasma NfL leveled off. …”
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Diagnostic performance of plasma p-tau217 in a memory clinic cohort using the Lumipulse automated platform
Published 2025-03-01Get full text
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Dissociation of Axonal Neurofilament Content from Its Transport Rate.
Published 2015-01-01“…The axonal cytoskeleton of neurofilament (NF) is a long-lived network of fibrous elements believed to be a stationary structure maintained by a small pool of transported cytoskeletal precursors. …”
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Effects of Alzheimer’s disease plasma marker levels on multilayer centrality in healthy individuals
Published 2025-01-01“…We aimed to address the relationship between centrality network changes and two plasma pathology markers: phosphorylated tau at threonine 231 (p-tau231), a proxy for early Aβ change, and neurofilament light chain (Nfl), a marker of axonal degeneration. …”
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Impact of transcranial Direct Current Stimulation on stereoscopic vision and retinal structure in adult amblyopic rodents
Published 2024-10-01“…Specifically, the thickness of the Nerve Fiber Layer + Ganglion Cell Layer + Inner Plexiform Layer (NFL+GCL+IPL) increased significantly in amblyopic eyes (p< 0.001). …”
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