Data-independent LC-MS/MS analysis of ME/CFS plasma reveals a dysregulated coagulation system, endothelial dysfunction, downregulation of complement machinery by Massimo Nunes, Mare Vlok, Amy Proal, Douglas B. Kell, Etheresia Pretorius

“…Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic condition that is characterized by unresolved fatigue, post-exertion symptom exacerbation (PESE), cognitive dysfunction, orthostatic intolerance, and other symptoms. …”
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Distinguishing glioblastoma from brain metastasis; a systematic review and meta-analysis on the performance of machine learning by Mohammad Amin Habibi, Reza Omid, Shafaq Asgarzade, Sadaf Derakhshandeh, Ali Soltani Farsani, Zohreh Tajabadi

“…The meta-analysis model results revealed a pooled sensitivity and specificity estimate of 0.83 [0.80–0.86] and 0.87 [0.83–0.90], respectively, indicating a commendable overall diagnostic accuracy across all the studies. ResNet50 and ResNet50-LSTM have shown promising results with single-study sensitivities of up to 88.9% and 88.2%, respectively. …”
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Biocompatibility of new cement based capping material prepared from eggshell and biopolymer (chitosan). by Hemn M. Sarmamy, Dara H. Saeed

“…The animals were divided into 3 groups, five rabbits for each group, for three time intervals (7, 14, and 21 days).Four specimens (4 mm long and 1 mm inner diameter) were inserted for each animal according to the following groups; Group 1: Empty pockets (control), Group 2: The Experimental material with a powder/liquid ratio of1 scoop: 8 drops by using glass slab with aid of cement metal spatula, Group 3: Mineral trioxide aggregate MTA which was mixed according to manufacturing instructions and Group 4: Biodentine which was mixed according to manufacturing instructions. …”
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Evaluation of osseointegration of dental implant with and without primary stability: An experimental study on sheep by Diyar M. Kheder, Ahmed A. Hayder

“…Forty implants were inserted, 20 implants in the study group (3.3 mm diameter and 8 mm length) and 20 implants in the control group (4.3 mm diameter and 8 mm length), after 3 months the 4 sheep were sacrificed and the universal torque ratchet and Periotest was used to measure the stability of the dental implants clinically. …”
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Therapeutic strategies for fungating and ulcerating breast cancers: A systematic review and narrative synthesis by Valentina Zagardo, Mandara Harikar, Gianluca Ferini

“…Methods: We conducted a systematic search of Medline, Embase, APA, PsycInfo, CAB abstracts, Scopus, and Web of Science from inception to June 30, 2024, including studies on patients with fungating, large, or ulcerating breast cancers. …”
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Patient Management in Non-Alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus by A. E. Bagriy, A. D. Zubov, M. V. Khomenko, E. S. Mikhailichenko, E. A. Pylaeva, N. A. Khaustova, E. V. Bryukhovetskaya

“…A body weight loss by 5–7 % or more (through caloric restriction or a bariatric surgery) promotes a marked reduction in liver fat and even reversal of steatohepatitis. Metered exercise exerts this effect even at insignificant weight loss. …”
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YTHDF2 mediates the protective effects of MG53 on myocardial infarction injury via recognizing the m6A modification of MG53 by Zhaojie Li, Kai Li, Jianqiang Zhao

“…Whether m6A modification on MG53 exerts a protective role on myocardial injury remains largely unknown. …”
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Geographic Variation and Trends in Laryngeal Cancer Incidence in Iran: A Comprehensive Analysis by Farimah Asghari, Hamideh Rashidian, Fereshteh Lotfi, Fatemeh Mahdavi Sabet, Zahra Faraji, Kazem Zendehdel

“… Background and Aims: Laryngeal cancer poses a significant health challenge, particularly in Iran, where it exerts a substantial burden on the healthcare system. …”
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The ubiquitin-conjugating enzyme UBE2D maintains a youthful proteome and ensures protein quality control during aging by sustaining proteasome activity. by Liam C Hunt, Michelle Curley, Kudzai Nyamkondiwa, Anna Stephan, Jianqin Jiao, Kanisha Kavdia, Vishwajeeth R Pagala, Junmin Peng, Fabio Demontis

“…However, some of the proteins that are concertedly up-regulated by aging and effRNAi are proteostasis regulators (e.g., chaperones and Pomp) that are transcriptionally induced presumably as part of an adaptive stress response to the loss of proteostasis. …”
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Factors Associated with Male Partner Support During Pregnancy and Child Birth in Kabale District. by Niwarinda, Denesi

“…Conclusion: The study recommends building capacity of health workers on male support, priotizing the adoption of resource package for engaging men in pregnancy and childbirth and its implementation, awareness through outreaches and media, incentives at each facility for male partners support and community engagement on male support in pregnancy and child birth.…”
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Factors Associated with Male Partner Support During Pregnancy and Child Birth in Kabale District. by Niwarinda, Denesi

“…Conclusion: The study recommends building capacity of health workers on male support, priotizing the adoption of resource package for engaging men in pregnancy and childbirth and its implementation, awareness through outreaches and media, incentives at each facility for male partners support and community engagement on male support in pregnancy and child birth.…”
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The Role of Agriculture in The Economic Development of Rural Areas: A Case Study of Kamuganguzi Sub-County Kabale District. by Turyatunga, Apollo

“…Rural farmers in agriculture development are one of the significant schemes through which empowerment of farmers, in tenns of provision of incentives, decision making, utility, and skill up gradation. …”
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The Role of Donations and Education Services in Kabale Municipality Kabale District. by Ampaire, Bronia

“…Some respondents showed that pupils are presented with bursaries, one-off money installments or prizes as part of impetus for enhancing participation and motivation in learning at school Incentives are viewed as more powerful than different mediations since they straightforwardly target children, as opposed to guardians, parental figures or instructors. …”
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Effect of High Alcohol Consumption Among the Youth in Kitumba Sub County-Kabale District. by Twijukye, Junior

“…Due to this, therefore, the research spearheaded the issue of exerting more efforts by the Community members and the Government. …”
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Emyooga Programme and Job Creation in Kabale District Uganda. by Niwasasira, Saviour

“…The purpose of the study was to examine the effect of the Emyooga programme on job creation in Kabale District since the programme’s inception in 2019. The study was guided by specific objectives which included: assessing the extent to which the Emyooga programme has contributed to job creation in Kabale District; examining the relationship between governance structures in the Emyooga programme and job creation in Kabale District; establishing the relationship between the capacity-building mechanisms in the Emyooga programme and job creation in Kabale District; and, to evaluate the relationship between infrastructure framework in the Emyooga programme and job creation in Kabale District. …”
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Diagnosis and Classification of Tuberculosis Chest X-ray Images of Children Less Than 15 years at Mbarara Regional Referral Hospital Using Deep Learning. by Kawuma, Simon, Kumbakumba, Elias, Mabirizi, Vicent, Nanjebe, Deborah, Mworozi, Kenneth, Mukama, Adolf Oyesigye, Kyasimire, Lydia

“…TL models; VGG16, VGG19, Inception V3, and ResNet50 outperformed scratch model with validation accuracy of 79.91%, 69.21%, 53.0%, 51.09% and 50.01% respectively. …”
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Effect of Integrated Pest Management in Banana Farms in Rwenkobwa Town Council Ibanda District. by Baguma, Christopher

“…To enhance IPM adoption, the government should expand extension services, introduce financial incentives, and implement demonstration projects to improve farmers' knowledge, reduce economic barriers, and showcase the practical benefits of IPM, ultimately promoting sustainable banana farming practices.…”
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Attention-Based Multi-Learning Approach for Speech Emotion Recognition With Dilated Convolution by Samuel, Kakuba, Alwin, Poulose

“…It has been applied in human-to-machine interaction applications like social living assistance, authentication, health monitoring and alertness systems. In order to ensure a good user experience, robust, accurate and computationally efficient deep learning models are necessary. …”
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The integration of hospital pharmacists into primary care settings in Shenzhen, China: a qualitative study by Zhiling Deng, Pengxiang Zhou, Yiting Lu, Zhengrong Li, Mi Yao, Yang Li, Chuan Zou, Haixin Li, Songtao Cai, Yi Guo, Yuling Tong, Yang Zhao, Zhijie Xu

“…Barriers to their integration include pharmacists’ inadequate competency, a lack of patient recognition, GPs’ resistance, and insufficient technological support. Patient needs, incentive systems, administrative leadership, social media use, and colocation were identified as facilitators of integration. …”
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Integrated microfluidics-based construction of anti-BTN2A2 gel droplet cell preparations for non-invasive tumor-infiltrating lymphocyte therapy by Yishen Tian, Jingxuan Li, Na Yang, Yang Zhao, Jiancao Zuo, Hang Xiong, Yiwen Pan, Li Xiao, Min Su, Feng Han, Zhixu He, Rong Hu

“…Specifically, the cell preparation exerted its anti-tumor effects through multiple mechanisms: Firstly, the surface BTN2A2 antibodies effectively inhibited the proliferation of Tregs and MDSCs within the tumor microenvironment; Secondly, leveraging the T cell antigen receptors (TCRs) present in the blood T cells, which were similar to those of tumor-infiltrating lymphocytes, significantly enhanced their targeting and cytotoxic capabilities; Furthermore, the CMP component within the droplets effectively promoted the infiltration of T cells into tumor tissues. …”
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