A Nomogram Based on Laboratory Data, Inflammatory Bowel Disease Questionnaire and CT Enterography for Activity Evaluation in Crohn’s Disease by Zhang H, Shen Y, Cao B, Zheng X, Zhao D, Hu J, Wu X

“…Multivariate logistic regression analysis identified the independent risk factors of erythrocyte sedimentation rate, fecal calprotectin, and Inflammatory Bowel Disease Questionnaire (IBDQ), and a nomogram was constructed in combination with rad-score. …”
Get full text

High Prevalence of Fatty Liver in Bangladeshi Adolescents and Young Adults with Type 2 Diabetes: Key Predictors and Screening Recommendations by Shil KK, Hasan M, Sultana N, Salam SBA, Mostafa SN, Hasanat MA

“…Fatty liver was significantly associated with older age, higher BMI, WHR, and a positive family history of diabetes. On multivariate analysis, age (OR 1.14, 95% CI 1.04– 1.25, p=0.004), positive family history of DM (OR 3.21, 95% CI 1.29– 8.22, p=0.012), acanthosis nigricans (OR: 5.05, 95% CI 1.59– 16.04, p=0.006), and fasting C-peptide levels (OR 1.46, 95% CI 1.10– 1.92; p = 0.007) were significant predictors of fatty liver.Conclusion: Fatty liver is highly prevalent in young-onset T2DM at diagnosis. …”
Get full text

Ultrasound feature-based nomogram model for predicting extrathyroidal extension in papillary thyroid carcinoma by Dong Guo, Chen Chen, Yin Zheng, Yue Shan, Shifei Huang, Tianhan Zhou, Yefei Yao, Zhengxian Zhang, Lu Wang, Dong Xu

“…Methods The training set retrospectively included 560 patients from two hospitals with preoperative ultrasound images showing capsule contact and confirmed as unifocal PTC by surgical pathology. …”
Get full text

Multidimensional predictive model for assessing clinical activity in thyroid eye disease by Yang Li, Yang Li, Yang Li, Guang-Hong Zhang, Guang-Hong Zhang, Guang-Hong Zhang, Man Tian, Man Tian, Man Tian, Chuan Hua, Chuan Hua, Chuan Hua, Chuan Hua, Jian-Ping Zhai, Jian-Ping Zhai, Jian-Ping Zhai, Yan-Qiong He, Yan-Qiong He, Yan-Qiong He, Xin-He Zuo, Xin-He Zuo, Xin-He Zuo, Xin-He Zuo

“…SPECT/CT-derived URmax correlated strongly with disease activity, while serum biomarkers complemented imaging limitations.ConclusionMultidimensional integration of clinical, imaging, and biomarker data significantly enhances TED activity evaluation compared to single-modality approaches. …”
Get full text

Personalized predictions of neoadjuvant chemotherapy response in breast cancer using machine learning and full-field digital mammography radiomics by Ye Ruan, Xingyuan Liu, Yantong Jin, Mingming Zhao, Xingda Zhang, Xiaoying Cheng, Yang Wang, Siwei Cao, Menglu Yan, Jianing Cai, Mengru Li, Bo Gao

“…ObjectiveThis study aimed to develop a comprehensive nomogram model by integrating clinical pathological and full-field digital mammography (FFDM) radiomic features to predict the efficacy of neoadjuvant chemotherapy (NAC) in breast cancer patients, thereby providing personalized treatment recommendations.MethodsA retrospective analysis was conducted on the clinical and imaging data of 227 breast cancer patients from 2016 to 2024 at the Second Affiliated Hospital of Harbin Medical University. …”
Get full text

Computational modelling reveals neurobiological contributions to static and dynamic functional connectivity patterns by Linnea Hoheisel, Linnea Hoheisel, Hannah Hacker, Gereon R Fink, Gereon R Fink, Silvia Daun, Silvia Daun, Joseph Kambeitz, Joseph Kambeitz

“…Recent advances in computational modelling allow us to investigate the relationship of both static FC (sFC) and dynamic FC (dFC) with neurobiology non-invasively.In this study, we modelled the brain activity of 200 healthy individuals based on empirical resting-state functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) data. …”
Get full text

Association of admission blood glucose and postoperation fast blood glucose with futile recanalization in patients with endovascular therapy by Dandan Chen, Yunqing Chen, Linghong Guo, Zubing Xu, Xian Liu, Xilin Xiong, Hudie Zhang, Yan Gong, Qiulong Yu, Chenying Zeng, Lanjiao Zhang, Qin Huang, Jinchong Zhang, Keji Zou, Xiaobing Li, Daojun Hong, Pu Fang, Jing Lin

“…Meanwhile, FR was more frequently observed in patients with postoperation hyperglycemia compared to patients without (68.5% vs. 51.4%, P = 0.001). Multivariate logistic regression analysis showed that postoperation hyperglycemia but not admission hyperglycemia remained a significant correlation with FR (OR = 1.676, 95% CI 1.028–2.732, P = 0.038). …”
Get full text

xCT as a Predictor for Survival in a Population‐Based Cohort of Head and Neck Squamous Cell Carcinoma by Linda Nissi, Sanni Tuominen, Johannes Routila, Teemu Huusko, Petra Ketonen, Maria Sundvall, Ilmo Leivo, Heikki Irjala, Heikki Minn, Tove J. Grönroos, Sami Ventelä

Get full text

The association between the gut microbiome and 24-h blood pressure measurements in the SCAPIS study by Yi-Ting Lin, Sergi Sayols-Baixeras, Gabriel Baldanzi, Koen F. Dekkers, Ulf Hammar, Diem Nguyen, Nynne Nielsen, Aron C. Eklund, Georgios Varotsis, Jacob B. Holm, H. Bjørn Nielsen, Lars Lind, Göran Bergström, J. Gustav Smith, Gunnar Engström, Johan Ärnlöv, Johan Sundström, Marju Orho-Melander, Tove Fall

“…Methods The association of gut microbial species and microbial functions, determined by shotgun metagenomic sequencing of fecal samples, with 24-h ambulatory blood pressure measurements in 3695 participants and office blood pressure was assessed in multivariable-adjusted models in 2770 participants without antihypertensive medication from the Swedish CArdioPulmonary bioImage Study. …”
Get full text

Ultrasound Microvascular Blood Flow Evaluation: A New Tool for the Management of Thyroid Nodule? by Carlo Cappelli, Ilenia Pirola, Elena Gandossi, Fiorella Marini, Alessandra Cristiano, Claudio Casella, Davide Lombardi, Barbara Agosti, Alberto Ferlin, Maurizio Castellano

“…Variables significantly associated with malignancy in the univariate analysis were gender (OR, 0.18; 95% CI, 0.08-0.37; p<0.001), vascularity (OR, 1.91; 95% CI, 1.65-3.89; p<0.001), and SMI (OR, 6.72; 95% CI, 3.89-11.59; p<0.001); multivariate logistic model confirmed SMI score 2 as an independent risk factor for malignancy (OR, 6.99; 95% CI, 3.46-12.09; p<0.001). …”
Get full text

The PaO2/FiO2 ratio on admission is independently associated with prolonged hospitalization in COVID-19 patients by Angelo Zinellu, Andrea De Vito, Valentina Scano, Panagiotis Paliogiannis, Vito Fiore, Giordano Madeddu, Ivana Maida, Elisabetta Zinellu, Arduino Aleksander Mangoni, Luigi Benedetto Arru, Ciriaco Carru, Sergio Babudieri, Pietro Pirina, Alessandro Giuseppe Fois

“…In ROC curve analysis, using a threshold of 248, the PaO2/FiO2 ratio predicted PHS with sensitivity and specificity of 60% and 91%, respectively (AUC = 0.780, 95% CI 0.637-0.886 p = 0.002). …”
Get full text

Distinct and content-specific neural representations of self- and other-produced actions in joint piano performance by Natalie Kohler, Natalie Kohler, Anna M. Czepiel, Anna M. Czepiel, Örjan de Manzano, Örjan de Manzano, Giacomo Novembre, Peter E. Keller, Peter E. Keller, Arno Villringer, Daniela Sammler, Daniela Sammler

“…What remains elusive, however, is whether and how own and partner actions can be represented simultaneously and distinctively in the sensorimotor system, and whether these representations are content-specific. Here, we applied multivariate pattern analysis (MVPA) to functional magnetic resonance imaging (fMRI) data of duetting pianists to dissociate the neural representation of self- and other-produced actions during synchronous joint music performance. …”
Get full text

Two-dimensional speckle tracking of the ascending aorta: a novel approach to evaluate arterial stiffness in pediatric patients with repaired conotruncal anomalies using echocardiog... by Anmol Goyal, Anmol Goyal, Anitha Parthiban, David A. White, David A. White, Daniel Forsha, Daniel Forsha, Doaa Aly

“…AAo GCS in repaired CTA patients had strong negative correlation with age (r = −0.76, CI −0.9 to −0.51) and a moderate negative correlation with the absolute aortic valve annulus (r = −0.55), absolute aortic root (r = −0.67), absolute sino-tubular junction (r = −0.67) and absolute AAo dimension (r = −0.71). On multivariate analysis, absolute aortic root and ascending aorta dimension were significantly associated with AAo GCS independent of other variables. …”
Get full text

Higher induction and maintenance infliximab trough levels are associated with radiological perianal fistula healing in pediatric patients with Crohn's disease by Joonhyuk Son, Sungjoo Park, Seon Young Kim, Yoon Zi Kim, Hansol Kim, Wontae Kim, Sanghoon Lee, Jeong-Meen Seo, Yon Ho Choe, Mi Jin Kim

“…Patients with radiological fistula healing had lower rates of reoperation (p = 0.021), and higher median IFX trough levels at week 2 (median, 17.6 vs. 14.1 μg/ml), week 6 (11.79 vs. 7.11 μg/ml), week 30 (3.9 vs. 1.1 μg/ml), and week 54 (7.6 vs. 3.7 μg/ml) (p = 0.043, 0.003, 0.007 and &lt;0.001, respectively) compared to those who had no fistula healing. In the multivariate analysis, higher median IFX trough levels at week 6 and week 54 remained significant factors associated with radiological fistula healing (p = 0.039 and 0.018, respectively). …”
Get full text

Determinants of malnutrition among adolescent females of age 15–19 years in an urban slum of Raipur city by Sakthi Das, Arvind Kumar Shukla, Abhiruchi Galhotra

“…This vulnerable group has low social power and is subjected to peer and social pressures related to body image and weight. All these factors along with the sociocultural milieu may lead to a spectrum of nutritional problems in them. …”
Get full text

Estimated glucose disposal rate outperforms other insulin resistance surrogates in predicting incident cardiovascular diseases in cardiovascular-kidney-metabolic syndrome stages 0–... by Bingtian Dong, Yuping Chen, Xiaocen Yang, Zhengdong Chen, Hua Zhang, Yuan Gao, Enfa Zhao, Chaoxue Zhang

Get full text

Assessment of Carotid Stiffness and Strain Parameters Using Speckle Tracking Strain Ultrasonography in Rheumatoid Arthritis Patients by Volkan Tasci, Ali Fuat Tekin, Huseyin Baygin, Alparslan Unsal, Mustafa Gok

“…After adjusting for confounding factors (age, gender, body mass index (BMI), and smoking status) using multivariate linear regression analysis, RA remained a significant predictor for all stiffness and strain parameters, except for the circumferential strain parameter DP. …”
Get full text

Prognostic role of atrial fibrillation in patients with non-compaction cardiomyopathy by S. M. Komissarova, N. M. Rineyskaya, O. P. Melnikova, T. V. Sevruk, A. A. Efimova

“…The rate of adverse cardiac events was significantly higher in patients with AF (74,1% vs 35,8%, χ2=23,93, p&lt;0,001) compared with patients without AF, including the incidence of TEEs (20,4% vs 5,6%, χ2=10,58, p=0,002) and HF progression to class III (46,3% vs 22,8%, χ2=10,9, p=0,002).Multivariate analysis showed that the following most significant predictors of HF progression risk: left ventricular ejection fraction (LVEF) &lt;50% according to cardiac MRI (hazard ratio (HR), 95,8; 95% confidence interval (CI), 10,2 -898,6; p=0,0001), presence of AF (HR, 8,2; 95% CI, 2,2-31,3; p=0,0022) and left atrial volume index (LAVI) &gt;43 ml/m2 (HR, 5,2; 95% CI, 2,1-12,8; p=0,0004); predictors of TEE risk were the presence of AF (HR, 6,5; 95% CI, 2,0-20,8; p=0,0020) and LAVI &gt;43 ml/m2 (HR, 6,0; 95% CI, 1,8-19,7; p=0,036). …”
Get full text

Prognostic value of primary gross tumor volume and standardized uptake value of F-FDG in PET/CT for distant metastasis in locoregionally advanced nasopharyngeal carcinoma by Ya-Nan Jin, Ji-Jin Yao, Si-Yang Wang, Wang-Jian Zhang, Guan-Qun Zhou, Fan Zhang, Zhi-Bin Cheng, Jun Ma, Hao-Yuan Mo, Ying Sun

“…A prognostic model was derived by SUVmax-N and clinical stage: low risk (SUVmax-N < 5.75 regardless of clinical stage), medium risk (stage III and SUVmax-N ≥ 5.75), and high risk (stage IV and SUVmax-N ≥ 5.75). Multivariate analysis revealed that SUVmax-N and the prognostic model remained independent prognostic factors for distant metastasis–free survival (p = 0.023 and p < 0.001, respectively), but the clinical stage became insignificant (p = 0.133). …”
Get full text

Left atrial strain predicts paroxysmal atrial fibrillation recurrence after catheter ablation: a 1-year study using three-dimensional speckle-tracking echocardiography by Rui Zhang, He Li, Yan Wang, Tianle Yu, Jiacheng Li, Yumeng Wu, Zhiwen Yu, Cuixing Liang, Dan Yu, Li Xue

“…Furthermore, left ventricular global longitudinal strain (LVGLS) and left ventricular global area strain (LVGAS) of the left ventricle showed improvement while maintaining a preserved left ventricular ejection fraction (LVEF) after RFCA(p < 0.05). Our multivariate regression analysis revealed that left atrial reservoir strain (LASr) independently predicted the recurrence of AF [odds ratio (OR), 1.19, 95% confidence interval (CI), 1.05–1.35, p = 0.005]. …”
Get full text