Impact of preprocedural anticoagulation on the incidence of silent cerebral embolisms after catheter ablation of atrial fibrillation in patients with low thromboembolic risk by Meng Wang, Wei Du, Ya-lan Fei, Hao Yang, Qing-shan Dong, Xian-jin Li, Shi-jie Li, Ru-xing Wang, Bing Han

“…The incidence of SCEs was significantly higher in the non-anticoagulation group compared with the anticoagulation group [22/92 [23.9%] vs. 3/49 [6.1%], P = 0.002]. Multivariate logistic regression analysis showed that the preprocedural application of OACs for more than 3 weeks was the only independent protective factor of SCEs after AF ablation.ConclusionAF ablation carried a substantial risk of SCEs even in patients with low thromboembolic risk. …”
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Associations of serum and tissue TIMP1 with host response and survival in colorectal cancer by Akseli Kehusmaa, Anne Tuomisto, Päivi Sirniö, Henna Karjalainen, Meeri Kastinen, Vilja V. Tapiainen, Ville K. Äijälä, Taina Tervahartiala, Timo Sorsa, Jukka Rintala, Sanna Meriläinen, Juha Saarnio, Tero Rautio, Markus J. Mäkinen, Juha P. Väyrynen

“…TIMP1 histoscore by cell type (tumor cell, other) was quantified using digital image analysis. Serum TIMP1 levels were evaluated for correlations with tumor TIMP1 expression, and their associations with tumor characteristics, inflammation, and prognosis were investigated. …”
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Factors affecting the primary patency of native arteriovenous fistulas after ultrasound-guided percutaneous transluminal angioplasty by Xue Xing, Qing Li, Yi Yang, Yanan Wang, Xiaona Zhan, Cailin Zhang, Gang Xu, Fan He

“…Kaplan–Meier’s survival curve was used to demonstrate the cumulative primary patency rate of UG-PTA. Univariate and multivariate Cox regression analysis was performed on clinical, anatomic, biochemical, and medication variables to identify the predictors of postintervention primary patency.Results The early technical success rate of UG-PTA was 98.4% (375/381). …”
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Can we predict neurological complications in patients with metastatic spinal tumors? by Chul Jung, Hee Tae Shin, Cho Rong Bae, Joon Hee Lee, Jin Hoon Park, Jae-Hwan Cho, Choong Guen Chee, Jae Yong Jeon

“…Multivariate analysis identified an ESCC grade 2 or 3 (high-grade ESCC) as the only significant predictor of spinal cord injury within 1 year (P = 0.016). …”
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Prognostic value of temporalis muscle thickness as a marker of sarcopenia in intracerebral hemorrhage by Waldemar Gubarev, Jan Klinke, Ulrike Voßmann, Daniel Cantré, Bijan Zendeh Zartoshti, Artem Rafaelian, Milos Arsenovic, Daniel Dubinski, Sae-Yeon Won, Florian Gessler, Thomas Freiman, Alexander Storch, Matthias Wittstock

“…The influence of sarcopenia assessed by TMT as the surrogate marker using head imaging (cCT, cMRT) on mRS was analyzed by ordinal regression analysis. …”
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The relation of radiological tumor volume response to histological response and outcome in patients with localized Ewing Sarcoma by Lianne M. Haveman, Andreas Ranft, Henk vd Berg, Anne Smets, Jarmila Kruseova, Ruth Ladenstein, Benedicte Brichard, Michael Paulussen, Thomas Kuehne, Heribert Juergens, Stephanie Klco‐Brosius, Uta Dirksen, Johannes H.M. Merks

“…No correlation was found between TVR and HisRes. Multivariate analysis showed that poor HisRes, pelvic location and late inadequate TVR were associated with poor outcome. …”
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APOE4 and chronic health risk factors are associated with sex-specific preclinical Alzheimer’s disease neuroimaging biomarkers by Genna M. Losinski, Mickeal N. Key, Eric D. Vidoni, Jonathan Clutton, Jill K. Morris, Jeffrey M. Burns, Amber Watts, Amber Watts

“…We identified AD risk factors including genetic (APOE genotype status) and health markers (fasting glucose, mean arterial pressure, waist-to-hip ratio, and android and gynoid body fat) associated with neuroimaging outcomes for which we observed sex differences.MethodsParticipants were sedentary, amyloid-β positive older adults (N = 112, ages 65–87 years) without evidence of cognitive impairment (CDR = 0).ResultsMultivariate analysis of covariance models adjusted for intracranial volume, age, and years of education demonstrated lower volume [F (7, 102) = 2.67, p = 0.014] and higher blood flow F (6, 102) = 4.25, p ≤ 0.001) among females compared to males in regions of interest connected to AD pathology and the estrogen receptor network. …”
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Risk factors and comorbidities associated with cardiac arrests and medical emergencies in interventional radiology patients by Husam Mohammed AlHarbi, Tarek Arabi, Yasser Saleh A. Alduribi, Hassan Shah, Ahmad Sabbah, Khalid Othman, Omar Bashir, Mohammad Arabi

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Hidden blood loss and risk factors after percutaneous endoscopic transforaminal lumbar interbody fusion by Meng Ge, Meng Ge, Fangbing Zhu, Fangbing Zhu, Weibin Du, Weibin Du, Zhengcong Ye, Zhengcong Ye, Zhenfei Xiong, Zhenfei Xiong, Lukai Zhang, Lukai Zhang, Hua Zhou, Hua Zhou, Jun Yang, Jun Yang

“…The risk factors were analyzed using single-factor correlation and multivariate linear regression analyses.ResultsOf the 83 patients, there were 42 males and 41 females. …”
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Clinical Efficacy of Ex Vivo Cross-Linking on Neovascularization of the Donor Cornea Carrier Tissue for the Boston Type I Keratoprosthesis by Ana M. Roldan, MD, Rohan Bir Singh, MD, Sofia De Arrigunaga, MD, Elizabeth L. Gatto, Alexander Melki, Steven J. Staffa, MS, David Zurakowski, MS, PhD, Nikolay Boychev, OD, PhD, MEd, Joseph B. Ciolino, MD

“…Subjects: Sixty-eight donor corneas were prospectively randomized 1:1 to receive either donor corneas that underwent ex vivo CXL or were non-CXL. The images of 47 corneas that were suitable for evaluation were included in the final analysis. …”
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Outcomes of Traumatic Liver Injuries at a Level-One Tertiary Trauma Center in Saudi Arabia: A 10-Year Experience by Nawaf AlShahwan, Saleh Husam Aldeligan, Salman T. Althunayan, Abdullah Alkodari, Mohammed Bin Manee, Faris Abdulaziz Albassam, Abdullah Aloraini, Ahmed Alburakan, Hassan Mashbari, Abdulaziz AlKanhal, Thamer Nouh

“…The overall mortality was 6.3%. Multivariate analysis revealed that shorter time to CT significantly reduced mortality risk (OR = 0.5, <i>p</i> < 0.05), while a positive e-FAST result was strongly associated with increased mortality (OR = 3.3, <i>p</i> < 0.05). …”
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Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study by Mariano Marrodan, María A. Piedrabuena, María A. Zarate, Sofía Rodríguez Murúa, Ezequiel I. Surace, Mauricio F. Farez, Marcela P. Fiol, María C. Ysrraelit, Jorge Correale

“…Statistical analyses included multivariate analyses of covariance (MANCOVA) and Cox regression to identify independent predictors of treatment failure. …”
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Preoperative pelvic floor muscle diameter as a predictor of postoperative urinary incontinence in robotic‐assisted laparoscopic total prostatectomy by Sho Hashimoto, Daisuke Obinata, Hideaki Uchida, Shigeyuki Arakawa, Yuki Inagaki, Ken Nakahara, Tsuyoshi Yoshizawa, Junichi Mochida, Kenya Yamaguchi, Satoru Takahashi

“…Nerve‐sparing procedures were also associated with faster recovery (p = 0.016). Multivariate analysis identified the thickness of both muscles as independent predictors of early continence recovery. …”
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Identifying low-risk breast cancer patients for axillary biopsy exemption: a multimodal preoperative predictive model by Jiaqi Zhang, Jianing Zhang, Zhihao Liu, Yudong Zhou, Xiaoni Zhao, Yalong Wang, Danni Li, Jinsui Du, Chenglong Duan, Yi Pan, Qi Tian, Feiqian Wang, Ke Wang, Lizhe Zhu, Bin Wang

“…Results LASSO, univariate, and multivariate logistic regression analyses revealed that estrogen receptor (ER) status (P = 0.007), ALN cortical–medullary boundary (P = 0.012), ALN cortical thickness (P < 0.001), short-axis diameter (P = 0.032), and the BI-RADS category on magnetic resonance imaging (MRI) (P = 0.021) were independent predictors of non-ALNM. …”
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Preoperative albumin-bilirubin grade combined with sarcopenia predicts long-term outcomes after laparoscopic gastrectomy for advanced gastric cancer by Shuangshuang Hou, Yang Yu, Nanbo Li, Wenjing Yu, Zhiyuan Dai, He Li, Lianyi Guo, Jiajun Yin, Ju Wu

“…Univariate and multivariate Cox regression analyses were performed to identify independent risk factors. …”
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Gross total resection in low-grade and pretreated high-grade invasive growth hormone pituitary adenomas promises favorable outcomes by Ting-Wei Chang, Chun-Chia Tseng, Yu-Chi Wang, Yin-Cheng Huang, Peng-Wei Hsu, Chi-Cheng Chuang, Cheng-Chi Lee

“…More significant differences were observed between biochemical remission and higher-grade Hardy–Wilson invasion grade (p = 0.0053 and 0.0075). Multivariate analysis showed that higher-grade Hardy–Wilson invasion correlated with resection status (p = 0.0481 and 0.0125); only resection status was associated with biochemical remission (p = 0.0101). …”
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Role of biomarkers of myocardial injury and inflammation in predicting ischemia-reperfusion injury in patients with ST-segment elevation acute coronary syndrome undergoing endovasc... by T. V. Rusak, L. G. Gelis, E. A. Medvedeva, I. I. Russkikh, N. A. Shibeko, S. A. Kurganovich, T. T. Gevorkyan

“…In addition, we analyzed biomarker levels in the early period after myocardial infarction, at which threshold values of reperfusion injury parameters were established as follows: for cTnI &gt;8,1 ng/ml, OR=7,17 (95% CI, 3,11-16,53, p=0,001); for hsCRP &gt;14 mg/L, OR=12,71 (95% CI, 5,03-32,08, p=0,001); for NTproBNP &gt;334 pg/ml, OR=11,8 (95% CI, 4,88-28,59, p=0,001); for sST2 &gt;41 ng/ml, OR=7,17 (95% CI, 3,11-16,53, p=0,001). According to multivariate analysis, predictors of microvascular injury were the initial NTproBNP values, as well as the cTnI, hsCRP, and sST2 values in the early postinfarction period (sensitivity — 89,5%, specificity — 83,3%).Conclusion. …”
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Ultrasound features and thyroid function of patients with papillary thyroid carcinoma for predicting metastatic cervical lymph nodes with atypical ultrasound features by Shuting Li, Wen Tang, Mengjuan Feng, Zonghui Zhang, Zhongping Tang, Yuanyuan Yue

“…A nomogram prediction model was established and evaluated for discrimination and calibration via receiver operating characteristic (ROC) curves, calibration curves, and 5-fold cross-validation.ResultsOf the 158 patients, 59 were assigned to the metastatic group, and 99 were assigned to the nonmetastatic group. Multivariate analysis revealed the following independent risk factors for metastatic cervical lymph nodes with atypical ultrasound features: age ≤ 45 years (OR=2.898, 95% CI=1.294-6.810), male sex (OR=3.224, 95% CI=1.468-7.333), contact with capsule (OR=7.346, 95% CI=2.448-27.049), internal blood flow (grade II-III, OR=4.915, 95% CI=1.626-15.882), and TGAb positivity (OR=5.173, 95% CI=2.026-14.355). …”
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The Prevalence and Characteristics of Embolic Stroke of Undetermined Source Among Sudanese Patients From November 2019 to March 2020: A Cross‐Section Study by Alaa Abdallah Idris Fadul, Mohammed Khalafalla Saees, Osman Amir

“…Normal echocardiography (64.7% vs. 17.3%; p value = 0.003) as well as carotid ultrasonography (US) findings (61.1% vs. 36.5%; p value = 0.002) were more prevalent in the ESUS group than in the SDS group. Multivariate analysis identified female gender (OR = 2.33; 95% CI: 1.76–7.16; p value = 0.016), normal findings on echocardiography (OR = 8.19; 95% CI: 2.76–24.32; p value 0.003), normal carotid Doppler ultrasound (OR = 5.0; 95% CI: 1.87–32.7; p value = 0.023), and normal ECG findings (OR = 3.5; 95% CI: 1.17–10.44; p value = 0.036) as significant predictors of ESUS. …”
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The role of proximal femoral bone, muscle and subcutaneous adipose tissue in the discriminating of hip fracture types in elderly women by Yangtong Li, Chenjun Liu, Jing Lu, Yuehua Li, Hui Sun

“…Results The univariate analysis showed that the correlation between most BMD parameters and HF was significantly stronger when compared to the correlation between muscle and MSAT parameters and HF. …”
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