Characterization of immunoreactivity with whole-slide imaging and digital analysis in high-grade serous ovarian cancer by Tiina Jäntti, Satu Luhtala, Johanna Mäenpää, Synnöve Staff

“…The aim of this study was to characterize tumor microenvironment in a retrospective cohort of high-grade serous carcinoma samples with whole-slide imaging and digital image analysis. Formalin-fixed paraffin-embedded high-grade serous carcinoma tumor tissue samples (n = 67) were analyzed for six immunohistochemical stainings: CD4, CD8, FoxP3, granzyme B, CD68, and CD163. …”
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Texture analysis of CT colonography to develop a novel imaging biomarker for the management of colorectal cancer by Hisashi Mamiya, Toru Tochigi, Koichi Hayano, Gaku Ohira, Shunsuke Imanishi, Tetsuro Maruyama, Yoshihiro Kurata, Yumiko Takahashi, Atsushi Hirata, Hisahiro Matsubara

“…Abstract Background Recent studies have focused on evaluating the biomarker value of textural features in radiological images. Our study investigated whether or not a texture analysis of computed tomographic colonography (CTC) images could be a novel biomarker for colorectal cancer (CRC). …”
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Integration of Multivariate Beta-based Hidden Markov Models and Support Vector Machines with Medical Applications by Narges Manouchehri, Nizar Bouguila

“…We apply our proposed model to medical applications, lung cancer detection, colonoscopy image, and colon tissue analysis. The results indicate that our proposed model could be a promising alternative.…”
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Analysis of imaging signatures in 18F-DOPA PET of glioblastoma treated with dose-escalated radiotherapy by Jing Qian, Deanna H. Pafundi, William G. Breen, Paul D. Brown, Christopher H. Hunt, Mark S. Jacobson, Derek R. Johnson, Timothy J. Kaufmann, Bradley J. Kemp, Sani H. Kizilbash, Val J. Lowe, Michael W. Ruff, Jann N. Sarkaria, Joon H. Uhm, Joon H. Uhm, Mark J. Zakhary, Maasa H. Seaberg, Hok Seum Wan Chan Tseung, Elizabeth S. Yan, Yan Zhang, Nadia N. Laack, Debra H. Brinkmann

“…Patients underwent pre-radiation and post-radiation 18F-DOPA PET scans on a prospective clinical trial. This analysis investigates quantitative image features correlated with prognosis and treatment response to identify patients who benefit the most from dose-escalated therapy.MethodsQuantitative image features from 18F-DOPA PET scans of 58 glioblastoma patients were extracted from the high uptake region (TBR>2.0) in both pre-RT and early post-RT follow-up PET images, which were then refined using Pearson pair correlation. …”
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Landslides susceptibility modelling using Multivariate Logistic Regression Model in the Sahla Watershed in Northern Morocco by Abdelhak El-Fengour, Hanifa El Motaki, Aissa El Bouzidi

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Regional network covariance patterns of white matter integrity related to cardiorespiratory fitness in healthy aging by Samantha G. Smith, Samantha G. Smith, Pradyumna K. Bharadwaj, Pradyumna K. Bharadwaj, David A. Raichlen, David A. Raichlen, Matthew D. Grilli, Matthew D. Grilli, Matthew D. Grilli, Jessica R. Andrews-Hanna, Jessica R. Andrews-Hanna, Georg A. Hishaw, Matthew J. Huentelman, Matthew J. Huentelman, Matthew J. Huentelman, Theodore P. Trouard, Theodore P. Trouard, Theodore P. Trouard, Gene E. Alexander, Gene E. Alexander, Gene E. Alexander, Gene E. Alexander, Gene E. Alexander, Gene E. Alexander

“…We used a multivariate analysis method, the Scaled Subprofile Model (SSM), to identify network patterns of MRI tract-specific white matter integrity (WMI) for AD, RD, MD, and FA related to VO2max and to evaluate their relation to demographic, vascular health, and dementia risk factors in 167 cognitively unimpaired older adults, ages 50 to 88. …”
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Comparative analysis of RGB and multispectral UAV image data for leaf area index estimation of sweet potato by Shoki Ochiai, Erika Kamada, Ryo Sugiura

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Analysis of features of papillary thyroid carcinoma on color Doppler ultrasound images: implications for lymph node metastasis by Lu Cao, Ying Cao, Xiangru Wang, Xinxin Lu, Fangxi Zhao, Lei Sun, Hua Wang, Xiaopeng Li

“…A multivariate analysis revealed that the garland pattern was an independent protective factor for LNM (OR [95% CI] = 0.386 [0.156–0.893]). …”
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Anterior Lens Curvature Matters in the Course of Primary Angle Closure: An Analysis Based on Ultrasound Biomicroscopic Imaging by Tingting Liu, Mengwei Li, Xiaoxiao Chen, Zhenying Jiang, Xiangmei Li, Xinghuai Sun, Jiajian Wang, Yuhong Chen

“…ALR, in addition to axial length (AL), anterior chamber depth (ACD), and lens thickness (LT), was compared among different groups using univariate and multivariate analysis with mixed effects linear model. …”
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A computational pipeline for image-based statistical analysis of biomolecular condensates dynamics using morphological descriptors by Ivan Rosa e Silva, Guilherme Gurian Dariani, Felipe Zanghelini Benevenutti, Renata Rocha de Oliveira, Vitória Yumi Uetuki Nicoleti, Murilo de Carvalho

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Estimation of Tomato Quality During Storage by Means of Image Analysis, Instrumental Analytical Methods, and Statistical Approaches by Paris Christodoulou, Eftichia Kritsi, Georgia Ladika, Panagiota Tsafou, Kostantinos Tsiantas, Thalia Tsiaka, Panagiotis Zoumpoulakis, Dionisis Cavouras, Vassilia J. Sinanoglou

“…A progressive transition in peel hue from orange to dark orange, and increased surface irregularity of their textural image were noted. Moreover, the combined use of instrumental and image analyses results via multivariate analysis allowed the clear discrimination of tomatoes according to storage days. …”
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Texture Analysis of 68Ga-DOTATOC PET/CT Images for the Prediction of Outcome in Patients with Neuroendocrine Tumors by Sara Pellegrino, Mariarosaria Panico, Roberto Bologna, Rocco Morra, Alberto Servetto, Roberto Bianco, Silvana Del Vecchio, Rosa Fonti

“…<b>Objectives</b>: The aim of our study is to evaluate whether texture analysis of 68Ga-DOTATOC PET/CT images can predict clinical outcome in patients with neuroendocrine tumors (NET). …”
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Cognitive mechanisms and temporal dynamics of negative emotion in facilitating congruency judgments by Yiheng Chen, Feier Fu, Qiwei Zhao, Yueyi Ding, Yingzhi Lu

“…Furthermore, multivariate pattern analysis showed that neural responses to emotional stimuli were evoked as early as 120 ms from stimulus onset, and the responses continued throughout the task, with a temporal separation between early emotion processing and late congruency judgments. …”
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Natural language processing for kidney ultrasound analysis: correlating imaging reports with chronic kidney disease diagnosis by Chenlu Wang, Ritwik Banerjee, Harry Kuperstein, Hamza Malick, Ruqiyya Bano, Robin L. Cunningham, Hira Tahir, Priyal Sakhuja, Janos Hajagos, Farrukh M. Koraishy

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Revisiting gliomatosis cerebri in adult-type diffuse gliomas: a comprehensive imaging, genomic and clinical analysis by Ilah Shin, Yae Won Park, Yongsik Sim, Seo Hee Choi, Sung Soo Ahn, Jong Hee Chang, Se Hoon Kim, Seung-Koo Lee, Rajan Jain

“…GC remained as an independent prognostic factor (HR = 1.25, P = 0.031) in IDH-wildtype glioblastoma patients on multivariable analysis, along with clinical, molecular, and surgical factors. …”
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A New Comprehensive Well Logging Data Method for Evaluating Fracture Reservoir Productivity and Its Application by SHEN Qinyu, LI Shengqing, CUI Yunjiang, SU Yuanda, WANG Peichun, TANG Xiaoming

“…There is a strong need for developing methods for evaluating the buried hill fracture reservoir productivity. By using a multivariate statistical method, the factor analysis, this paper integrates the results of various logging methods, including acoustic, resistivity, borehole wall imaging, and other logging data to obtain controlling factors for the reservoir fluid transport property. …”
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Multivariate metal-organic frameworks enable chemical shift-encoded MRI with femtomolar sensitivity for biological systems by Qingbin Zeng, Quer Yue, Ming Zhang, Rui Zhou, Zhen Wang, Zhongyu Xiao, Yaping Yuan, Xiuchao Zhao, Weiping Jiang, Lei Zhang, Yuqi Yang, Minghui Yang, Haidong Li, Louis-S. Bouchard, Qianni Guo, Xin Zhou

“…Magnetic resonance imaging (MRI) offers deep tissue penetration. When combined with chemical shift-encoded MRI reporters, it enables in vivo chemical shift encoding for biotarget imaging and analysis. …”
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UV Hyperspectral Imaging and Chemometrics for Honeydew Detection: Enhancing Cotton Fiber Quality by Mohammad Al Ktash, Mona Knoblich, Frank Wackenhut, Marc Brecht

“…This study investigates ultraviolet (UV) hyperspectral imaging (230–380 nm) combined with multivariate data analysis to detect and quantify honeydew contaminations in real cotton samples. …”
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Sagittal Realignment Following Decompression for Lumbar Spinal Stenosis in Elderly Patients: A Comprehensive EOS Imaging Analysis by Hyung-Youl Park, Ho-Young Jung, Geon-U Kim, Se-Heon Lee, Jun-Seok Lee

“…Patients were grouped based on the improvement of the sagittal vertical axis (SVA) by 25 mm or more. A multivariate analysis was performed to identify factors affecting sagittal alignment changes. …”
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Magnetic-Resonance-Imaging Texture Analysis Predicts Early Progression in Rectal Cancer Patients Undergoing Neoadjuvant Chemoradiation by Valerio Nardone, Alfonso Reginelli, Fernando Scala, Salvatore Francesco Carbone, Maria Antonietta Mazzei, Lucio Sebaste, Tommaso Carfagno, Giuseppe Battaglia, Pierpaolo Pastina, Pierpaolo Correale, Paolo Tini, Gianluca Pellino, Salvatore Cappabianca, Luigi Pirtoli

“…Then we performed univariate and multivariate analysis, and a ROC curve was also generated. …”
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