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Towards Phenotyping Characteristics and Mechanism of Conduction Delay in Patients With Nonischemic Heart Failure With Reduced Ejection Fraction: Insights From Cardiac Magnetic Reso...
Published 2025-05-01“…Methods A retrospective analysis was conducted on 887 consecutive patients with nonischemic heart failure with reduced ejection fraction and prolonged QRS duration who underwent cardiac magnetic resonance imaging, as well as 200 subjects with heart failure with reduced ejection fraction and normal QRS duration as the control group. …”
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Glymphatic System Dysfunction in Elderly Patients with Late-Onset Epilepsy and Comorbid Chronic Insomnia Revealed by Diffusion Tensor Imaging Along the Perivascular Space (DTI-ALPS...
Published 2025-08-01“…Simoa assays were performed to quantify Aβ 42 and Aβ 40 as plasma biomarkers of age-related neuropathology, and associations between the DTI-ALPS index and age, seizure frequency and duration, Sleep Quality Index (PSQI), Hamilton Rating Scale for Depression (HAMD), Hamilton Rating Scale for Anxiety (HAMA), Mini-Mental State Examination (MMSE), and Aβ 42:Aβ 40 ratio (Aβ 42/40) were assessed using Spearman correlation tests and multivariate logistic regression models.Results: Both DTI-ALPS index and Aβ 42/40 were significantly lower among LOE patients compared to HCs, and post-hoc analysis revealed even lower Aβ 42/40 and DTI-ALPS index values among LOE patients with comorbid chronic insomnia compared to HCs and LOE patients without chronic insomnia. …”
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Association of Perineural Invasion of Adenocarcinoma in Prostate Biopsy with Pathological and Clinical Outcomes
Published 2025-08-01“…However, perineural invasion was significantly associated with higher pathological T stage (pT2, pT3a, pT3b) (p < 0.001), including extraprostatic extension (pT3 disease) in univariate analysis. Multivariate analysis demonstrated a notable correlation between the pathological T stage and 2-year disease-free survival (p < 0.001). …”
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Morphologic and functional alterations in the parasagittal dural space in mild cognitive impairment
Published 2025-07-01“…MCI patients had significantly larger PSD volume (P = 0.023), a lower peak wash-in rate (P < 0.001), and delayed time to first peak (P = 0.001) compared to controls. In multivariate regression analysis, PSD volume (β = -0.579, 95% CI [-1.072 – -0.086], P = 0.023) and wash-out rate (β = -3.293, 95% CI [-6.351 – -0.235], P = 0.036) were significantly associated with the Mini-Mental State Examination (MMSE) score. …”
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Baseline magnetic resonance imaging findings associated with short-term clinical outcomes after intraarticular administration of autologous adipose-derived stem cells for knee oste...
Published 2025-03-01“…Lower OA grade (odds ratio [OR]: 0.52; 95 % confidence interval (CI): 0.31–0.88; P = 0.015), smaller BMLs in medial femoral condyle (OR: 0.36; 95 % CI: 0.14–0.94; P = 0.037), and less meniscal extrusion (OR: 0.31; 95 % CI: 0.11–0.89; P = 0.029) were associated with higher responder rate at 6 months in multivariable logistic regression analysis. The factors associated with higher responder rate at 12 months included lower OA grade (OR: 0.42; 95 % CI: 0.25–0.73; P = 0.002) and younger age (OR: 1.04; 95 % CI: 1.00–1.08; P = 0.042). …”
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Integration of amide proton transfer-weighted imaging and methionine positron emission tomography histogram parameters enhances the prediction of isocitrate dehydrogenase mutations...
Published 2025-04-01“…Diagnostic performance was assessed using receiver operating characteristic (ROC) curve analysis, and combined models of the two parameters were constructed using multivariable logistic regression. …”
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Analysis and prediction of condylar resorption following orthognathic surgery
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Protein Extraction Methods Suitable for Muscle Tissue Proteomic Analysis
Published 2024-09-01“…The efficacies of the methods were assessed by performing an image analysis of the 2DE gels and by statistical and multivariate analyses. …”
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Reirradiation based on diffusion-weighted magnetic resonance imaging-guided dose- painting for locally advanced recurrent nasopharyngeal carcinoma: a phase 2 randomized controlled...
Published 2025-04-01“…Grade 3–4 toxicities between the two groups showed no significant difference. Multivariate analysis revealed that DWI-guided DP-IMRT was an independent prognostic factor for PFS and LRFS. …”
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Development and validation of a machine learning model for central compartmental lymph node metastasis in solitary papillary thyroid microcarcinoma via ultrasound imaging features...
Published 2025-07-01“…Independent risk factors, along with radiomics features identified through multivariate logistic regression analysis, were subsequently refined through additional feature selection techniques to develop combined predictive models. …”
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Periprostatic fat magnetic resonance imaging based radiomics nomogram for predicting biochemical recurrence-free survival in patients with non-metastatic prostate cancer after radi...
Published 2024-11-01“…ROC analyses showed that the Area Under the Curve (AUC) of the periprostatic fat-intratumoral radiomics model demonstrated the highest AUC at 0.921 (95%CI, 0.857–0.981), 0.875 (95%CI, 0.763–0.950), 0.854 (95%CI, 0.706–0.923) for 1-year, 3-years and 5-years bRFS. Multivariate Cox regression analysis revealed that Pathological T stage, ISUP grading group and Positive surgical margin were independent prognostic factors for predicting bRFS. …”
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Prognostic Value of Gd-BOPTA Enhanced MRI in Solitary Resected Hepatocellular Carcinoma Without Microvascular Invasion
Published 2025-07-01“…Multivariate Cox regression analysis revealed that HBeAg positive, tumor growth subtype, non-peripheral washout, mosaic architecture, and internal arteries were independent prognostic factors for RFS in patients with solitary HCC without MVI. …”
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Comprehensive analysis of the expression and prognostic value of ARMCs in pancreatic adenocarcinoma
Published 2025-01-01“…Immunohistochemistry (IHC) was also performed. Then Image-J was used to analyze all images obtained from the experiment, and GraphPad-Prism (9.5.1) was used for statistical analysis to verify the expression of ARMCs in PAAD. …”
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Analysis of influencing factors on hospitalization time for mild ischemic colitis
Published 2025-04-01“…Factors with statistical significance in univariate analysis were included in multivariate Logistic regression analysis to identify risk factors influencing hospitalization duration. …”
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Langerhans cell histiocytosis of the jaw: clinical analysis of 68 cases
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Risk factor analysis for cardiac abnormalities in patients with idiopathic scoliosis
Published 2025-05-01“…The records of echocardiography, spinal radiographs and magnetic resonance imaging were reviewed. Calculate the proportion of congenital heart disease and cardiac abnormalities related to heart valves in patients with IS, and screen the risk factors by multivariate analysis. …”
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An Additional 30-s Observation of the Right-Sided Colon Using a Novel Endoscopic System with Texture and Color Enhancement Imaging Decreases Polyp Miss Rates: A Multicenter Study
Published 2025-07-01“…Adenoma and sessile serrated lesion (SSL) detection rate (ASDR) and adenoma detection rate (ADR) were examined. Multivariate analysis identified factors influencing lesion detection using the Add-30s TXI. …”
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