Elucidating the aluminum storage mechanism in cobalt sulfide cathode materials for advanced batteries by Ruiyuan Zhuang, Ruiyuan Zhuang, Yongqing Li, Junhong Wang, Jianfeng Zhan, Jiangnan Yan, Yaru Chen, Wenhui Mo, Jun Zhang, Jun Zhang

“…These findings provide fundamental insights for designing high-kinetics transition metal sulfide cathodes and advance the development of practical multivalent-ion battery systems.…”
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Active poly‐GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model by Qihui Zhou, Nikola Mareljic, Meike Michaelsen, Samira Parhizkar, Steffanie Heindl, Brigitte Nuscher, Daniel Farny, Mareike Czuppa, Carina Schludi, Alexander Graf, Stefan Krebs, Helmut Blum, Regina Feederle, Stefan Roth, Christian Haass, Thomas Arzberger, Arthur Liesz, Dieter Edbauer

“…To overcome poor immunogenicity, we compared the antibody response of multivalent ovalbumin‐(GA)10 conjugates and pre‐aggregated carrier‐free (GA)15. …”
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Crystal structure transformation and lattice impurities migration of quartz during chlorine roasting by Wenda Guo, Haolong Lu, Zhenyue Zhang, Ling Jiang, Hanjun Wu, Defeng Liu, Ruan Chi

“…The variation of crystal structure and the lattice impurities migration of quartz during chlorine roasting were studied through in-situ XRD, TGA, SEM-EDS, ICP-MS, FT-IR and XPS analysis. It revealed that the decomposable impurities H2O, −OH, and residual collectors in the crystal of purified quartz could be effectively removed through chlorine roasting above 900 °C, which also had an obvious effect on the removal of low-valence trace elements Li, Na and K in the crystal of quartz but didn’t affect the multivalent trace elements Al and Ti. …”
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Emerging trends in synthesis, characterization, and mechanism of action of antibody-drug and antibody-nanoparticle conjugates by Tanu Dixit, Annamraju Aswini, Harshal Nikam, Anuradha Vaidya, Selvan Ravindran

“…ACNPs also facilitate multivalent binding by functionalizing multiple antibody molecules on their surface, improving target cell recognition and binding strength. …”
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Ellipsometric Surface Oxidation Model of ALD-Grown Vanadium Oxide Mixed-Valence System by Xiaojie Sun, Shuguang Wang, Qingyuan Cai, Jingze Liu, Changhai Li, Ertao Hu, Jing Li, Songyou Wang, Yuxiang Zheng, Liangyao Chen, Youngpak Lee

“…This study is expected to help with the analysis of vanadium oxide mixed-valence systems and other multivalent metal oxide systems.…”
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Development and Efficacy Evaluation of a Novel Nanoparticle-Based Hemagglutination Inhibition Assay for Serological Studies of Porcine Epidemic Diarrhea Virus by Fengyan Liang, Wenyue Qiao, Mengjia Zhang, Zhangtiantian Hu, Shan Zhao, Qigui Yan, Wentao Li, Yifei Lang

“…Electron microscopy and dynamic light scattering analysis confirmed its topology, and the hemagglutination assay showed that S1^0A-NPs can efficiently agglutinate red blood cells. …”
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Nanomaterials in targeting amyloid-β oligomers: current advances and future directions for Alzheimer's disease diagnosis and therapy by Shiwani Randhawa, Trilok Chand Saini, Manik Bathla, Rahul Bhardwaj, Rubina Dhiman, Amitabha Acharya

“…In recent years, nanomaterials (NMs) have emerged as promising agents for addressing AβOs regarding their multivalent interactions, which can more effectively detect and inhibit AβO formation. …”
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Immunizing adult female mice with a TcpA-A2-CTB chimera provides a high level of protection for their pups in the infant mouse model of cholera. by Gregory A Price, Randall K Holmes

“…These data support the concept of including both TcpA and CTB as immunogens in development of an effective multivalent subunit vaccine against V. cholerae.…”
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The potential use of nanozymes as an antibacterial agents in oral infection, periodontitis, and peri-implantitis by Mohammad Hosseini Hooshiar, Ashkan Badkoobeh, Shirin Kolahdouz, Azadeh Tadayonfard, Asieh Mozaffari, Kamyar Nasiri, Sara Salari, Reza Safaralizadeh, Saman Yasamineh

“…A family of nanoparticles known as nanozymes (NZs) comprise highly catalytically active multivalent metal components. The most often employed NZs with antibacterial activity are those that have peroxidase (POD) activity, among other types of NZs. …”
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Simple and High-Throughput Quantification of Mono- and Bivalent Foot-and-Mouth Disease Virus Vaccine Antigens by Differential Scanning Fluorimetry by Yanli Yang, Xiaojie Chen, Ming Li, Fei Xin, Yi Zhao, Chengfeng Zhang, Yiping Pan, Chuanyu He, Sun He

“…Using a multiple linear regression analysis, the simultaneous quantification of A and O FMDV in the bivalent mixtures achieved recovery rates of 82.4–105.5%, with an RSD < 10% for most of the samples. …”
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Biomimetic phosphorus dendrimer multi-epitope nanovaccine enhances humoral and cellular immune response against African swine fever virus by Hong Duan, Aijuan Shen, Min Wang, Fengxia Zhang, Ziheng Zhang, Yaci Zhang, Yunshuo Lu, Qiming Pei, Angke Zhang

“…Abstract Using nanoparticles (NPs) as a platform for multivalent antigen display is an effective strategy to increase the immunogenicity of subunit vaccines, which can induce high levels of humoral and cellular immunity. …”
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Structure activity relationship of dendrimer microbicides with dual action antiviral activity. by David Tyssen, Scott A Henderson, Adam Johnson, Jasminka Sterjovski, Katie Moore, Jennifer La, Mark Zanin, Secondo Sonza, Peter Karellas, Michael P Giannis, Guy Krippner, Steve Wesselingh, Tom McCarthy, Paul R Gorry, Paul A Ramsland, Richard Cone, Jeremy R A Paull, Gareth R Lewis, Gilda Tachedjian

“…However, the anti-HIV and HSV structure-activity relationship of dendrimers comprising benzyhydryl amide cores and lysine branches, and a comprehensive analysis of their broad-spectrum anti-HIV activity and mechanism of action have not been published.…”
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High-risk human papillomavirus (hr-HPV) prevalence and abnormal cervical cytology in rural high-altitude communities: a population-based cross-sectional study in the Southern Tibet... by Min Chen, Yeshi Lhamo, Kelsang Chödrön, Le Chen

“…These findings support prioritizing multivalent vaccines in this high-altitude population.…”
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A Phase II, Randomised, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy of HEX17, a Novel Broad-Spectrum Antiviral Drug, in a Controlled Human Infection Model of In... by Geoff Kitson, Marion Byford, Lindsey Cass, David Howat, Brigitte Köhn, Alessandra Bisquera, Andrew Catchpole, Nicolas Noulin, Douglas Thomson

“…Abstract Introduction Viral respiratory tract infections are of global concern, with an unmet need for a broad-spectrum antiviral prophylactic. HEX17, a multivalent carbohydrate-binding module, binds to sialic acid, a cell surface glycan used by many viruses for host cell entry. …”
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Biosynthesis of Two Types of Exogenous Antigenic Polysaccharides in a Single <i>Escherichia coli</i> Chassis Cell by Jingjing Hao, Haoqian Liao, Shuhong Meng, Yan Guo, Li Zhu, Hengliang Wang, Yufei Lyu

“…The approach holds significant promise for the rational design and production of multivalent conjugate vaccines targeting drug-resistant pathogens.…”
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Immunological Responses to Tetanus and Influenza Vaccination in Donkeys by Maciej Perzyna, Jowita Grzędzicka, Dominika Milczek‐Haduch, Izabela Dąbrowska, Michał Trela, Bartosz Pawliński, Olga Witkowska‐Piłaszewicz

“…Animals were selected based on clinical health assessment and confirmed seronegativity for tetanus and equine influenza. All received a multivalent vaccine containing tetanus toxoid and equine influenza antigens. …”
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Recent advances on coxsackievirus A6 vaccine research by Xianfeng Zhou, Xianfeng Zhou, Han Mo, Hui Li, Fenglan He, Qian Yang, Qian Yang, Qian Yang

“…In light of the recurrent recombination of CVA6 and the evolution of pathogen profiles, the recommendation is made for the future development of multivalent and mRNA vaccines, which hold significant potential in the prevention and control of CVA6 and other major dominant serotypes.…”
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Effectiveness of Wolbachia-infected mosquito deployments in reducing the incidence of dengue and other Aedes-borne diseases in Niterói, Brazil: A quasi-experimental study. by Sofia B Pinto, Thais I S Riback, Gabriel Sylvestre, Guilherme Costa, Julia Peixoto, Fernando B S Dias, Stephanie K Tanamas, Cameron P Simmons, Suzanne M Dufault, Peter A Ryan, Scott L O'Neill, Frederico C Muzzi, Simon Kutcher, Jacqui Montgomery, Benjamin R Green, Ruth Smithyman, Ana Eppinghaus, Valeria Saraceni, Betina Durovni, Katherine L Anders, Luciano A Moreira

“…The wMel intervention effect was estimated by controlled interrupted time series analysis of monthly dengue, chikungunya and Zika case notifications to the public health surveillance system before, during and after releases, from release zones and the control zone. …”
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Epidemiological, etiological, and serological characteristics of hand, foot, and mouth disease in Guizhou Province, Southwest China, from 2008 to 2023. by Fajin Li, Dan Wang, Fei Su, Suye Zhao, Jun Guo, Fumin Zhang, Xueqin Ran, Jiafu Wang, Shijun Li

“…Currently, there is an urgent need to develop multivalent vaccines and implement effective measures to reduce incidence of HFMD.…”
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Overcoming challenges of developing a live-attenuated dengue vaccine and the path forward by Dr Walid Kandeil, Dr Mayuri Sharma

“…Additional immunogenicity analysis across phase I/II/III trials revealed engagement of long-lasting tetravalent, functional antibody, and cell-mediated immune responses directed against the structural and nonstructural components of the vaccine, irrespective of baseline serostatus. …”
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