-
141
Nano theranostics involved in bladder cancer treatment
Published 2023-04-01“…Bladder cancer (BC) is a complex disease with multiple clinical manifestations and treatment challenges, and current standard-of-care therapies remain limited and unfavorable. …”
Get full text
Article -
142
Prediction model, risk factor score and ventilator-associated pneumonia: A two-stage case-control study
Published 2025-02-01“…Conclusions: Results of this study revealed co-occurrence of multiple predictors for VAP risk. The risk factor scoring system proposed is a potentially useful predictive tool for clinical targets for VAP prevention.…”
Get full text
Article -
143
Reductive acetogenesis is a dominant process in the ruminant hindgut
Published 2025-01-01Get full text
Article -
144
Sporadic Dips from Extended Debris Transiting the Metal-rich White Dwarf SBSS 1232+563
Published 2025-01-01“…We present the discovery of deep but sporadic transits in the flux of SBSS 1232+563, a metal-rich white dwarf polluted by disrupted exoplanetary debris. …”
Get full text
Article -
145
More Efficient and Reliable: Identifying RRab Stars with Blazhko Effect by Deep Convolutional Neural Network
Published 2025-01-01“…The physical origin of the Blazhko effect (BL), a phenomenon of a single or multiple periodic modulation(s) of the light curve, is under debate. …”
Get full text
Article -
146
-
147
Epigenome-wide association study of perceived discrimination in the Multi-Ethnic Study of Atherosclerosis (MESA)
Published 2025-12-01“…We conducted both race/ethnicity-stratified analyses as well as trans-ancestry meta-analyses. At false discovery rate of 10%, 7 CpGs and 4 differentially methylated regions (DMRs) containing 11 CpGs were associated with perceived discrimination exposures in at least one racial/ethnic group or in meta-analysis. …”
Get full text
Article -
148
Advances and trends of modern and contemporary research on the geology of coal-measure minerals in China
Published 2025-01-01“…Advances Based on textual research and the analysis of logical relations, this study generalized the advances in research on the geology of CMMs in China into four aspects. (1) Increasingly improved geological theory system of CMMs: China’s classic theoretical system of coal field geology was formed in the second half of the 20th century, and the geological theory system focusing on coals, coal-measure gas, and coal-measure critical metals has been gradually developed since the 21st century. (2) Research on the origin and genesis of coals, advancing the international coal geology: The advancements include the development of the new coal metamorphism theory, the discovery of the world's youngest soft lignite, the reveal of late-stage coalification jumps, the establishment of the ordinary organic petrology, and the comprehensive ascertainment of the formation and evolutionary mechanisms of coals. (3) The unique CMM accumulation, distribution, and metallogenic theory: The specific outcomes include the establishment of multiple sedimentary and structural coal-controlling patterns, the reveal of the fundamental framework of coal accumulation in sea areas, the identification of deposits of various coal-measure critical metals, and the determination of the division schemes for coal-controlling geotectonic units and the metallogenic zones of coal-measure critical metals, and the development of a geological theory system for coalbed methane. (4) Significant achievements in the geological surveys and assessment of special coal resources: Specifically, the methodological system for the geological prediction and assessment of special coal types and high-quality, eco-friendly, and clean coal resources has been developed, the methodological system for the resource potential assessment of tar-rich coals and underground coal gasification has been formed, and the coal resources for related purposes have been preliminarily investigated. …”
Get full text
Article -
149
KGRDR: a deep learning model based on knowledge graph and graph regularized integration for drug repositioning
Published 2025-02-01“…Computational drug repositioning, serving as an effective alternative to traditional drug discovery plays a key role in optimizing drug development. …”
Get full text
Article -
150
Machine learning potential predictor of idiopathic pulmonary fibrosis
Published 2025-01-01“…Furthermore, GSEA revealed enrichment in multiple pathways, while immune function analysis demonstrated a significant correlation between IPF onset and immune cell infiltration. …”
Get full text
Article -
151
-
152
Light and dark biofilm adaptation impacts larval settlement in diverse coral species
Published 2025-01-01“…Although these taxa were generally specific to each coral species, we observed bacteria classified as Flavobacteriaceae, Rhodobacteraceae, Rhizobiaceae and Pirellulaceae to be consistently correlated with larval settlement across multiple coral species. Conclusions Our work identifies novel microbial groups that significantly influence coral larval settlement, which can be targeted for the discovery of settlement-inducing metabolites for implementation in reef restoration programs. …”
Get full text
Article -
153
Engineering of Dihydroxy Biphenyl Dioxygenase Enzyme to Improve Its Performance In Removing PCBs: A Molecular Docking Study
Published 2024-10-01“…Materials and Methods: The amino acid sequence of the enzyme was obtained from the UniPprot database and to check similar sequences with PSI-BLAST method, similar sequences were searched from close to distant protein species. By performing multiple alignments of PSI-BLAST sequences, 250 sequences were matched. …”
Get full text
Article -
154
Causal relationship between immune cells and risk of heart failure: evidence from a Mendelian randomization study
Published 2025-01-01“…Sensitivity analyses were conducted to validate the strength and reliability of the MR findings.ConclusionsOur study suggests that there appears to be a causal effect between multiple immune cells on heart failure. This discovery provides a new avenue for the development of therapeutic treatments for HF and a new target for drug development.…”
Get full text
Article -
155
-
156
A Comprehensive Analysis of <i>Echinococcus granulosus</i> Infections in Children and Adolescents: Results of a 7-Year Retrospective Study and Literature Review
Published 2025-01-01“…The results show that incidental discovery, symptoms, complications, multiple dissemination, pulmonary involvement, and dog and pig contact increase the hospitalization time. …”
Get full text
Article -
157
A Novel Stacked Model for Classification of Vocal Cord Paralysis Over Imbalanced Vocal Data
Published 2025-01-01“…The aforementioned gave adequate results over the dataset of voice recordings of the vowel that either have a balanced dataset across all the classes or multiple voice pathologies are selected to bring the balance in the dataset equal to healthy subjects. …”
Get full text
Article -
158
-
159
The curvilinear relationship between Framingham Steatosis Index and depression: insights from a nationwide study
Published 2025-01-01“…We investigated the association between FSI and depression using a weighted multiple logistic regression model and stratified analysis. …”
Get full text
Article -
160
Altered expression of miRNA profile in peripheral blood mononuclear cells following the third dose of inactivated COVID-19 vaccine
Published 2025-01-01“…Bioinformatic analysis suggested that miR-25-5p, miR-34c-3p, and miR-206 may target multiple pathways involved in immune regulation and inflammation. …”
Get full text
Article