Showing 141 - 160 results of 215 for search 'Multiple discovery', query time: 0.06s Refine Results
  1. 141

    Nano theranostics involved in bladder cancer treatment by Kunpeng Liu, Qixi Mo, Zhenshan Ding, Shicong Lai, Jian Ren, Qingsong Yu

    Published 2023-04-01
    “…Bladder cancer (BC) is a complex disease with multiple clinical manifestations and treatment challenges, and current standard-of-care therapies remain limited and unfavorable. …”
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  2. 142

    Prediction model, risk factor score and ventilator-associated pneumonia: A two-stage case-control study by Hua Meng, Yuxin Shi, Kaming Xue, Di Liu, Xiongjing Cao, Yanyan Wu, Yunzhou Fan, Fang Gao, Ming Zhu, Lijuan Xiong

    Published 2025-02-01
    “…Conclusions: Results of this study revealed co-occurrence of multiple predictors for VAP risk. The risk factor scoring system proposed is a potentially useful predictive tool for clinical targets for VAP prevention.…”
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  3. 143
  4. 144

    Sporadic Dips from Extended Debris Transiting the Metal-rich White Dwarf SBSS 1232+563 by J. J. Hermes, Joseph A. Guidry, Zachary P. Vanderbosch, Mariona Badenas-Agusti, Siyi Xu, Malia L. Kao, Antonio C. Rodriguez, Keith Hawkins

    Published 2025-01-01
    “…We present the discovery of deep but sporadic transits in the flux of SBSS 1232+563, a metal-rich white dwarf polluted by disrupted exoplanetary debris. …”
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    Article
  5. 145

    More Efficient and Reliable: Identifying RRab Stars with Blazhko Effect by Deep Convolutional Neural Network by Nan Jiang, Tianrui Sun, Siyuan Pan, Lingzhi Wang, Xue Li, Bin Sheng, Xiaofeng Wang

    Published 2025-01-01
    “…The physical origin of the Blazhko effect (BL), a phenomenon of a single or multiple periodic modulation(s) of the light curve, is under debate. …”
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  6. 146
  7. 147

    Epigenome-wide association study of perceived discrimination in the Multi-Ethnic Study of Atherosclerosis (MESA) by Wei Zhao, Lisha Lin, Kristen M. Kelly, Lauren A. Opsasnick, Belinda L. Needham, Yongmei Liu, Srijan Sen, Jennifer A. Smith

    Published 2025-12-01
    “…We conducted both race/ethnicity-stratified analyses as well as trans-ancestry meta-analyses. At false discovery rate of 10%, 7 CpGs and 4 differentially methylated regions (DMRs) containing 11 CpGs were associated with perceived discrimination exposures in at least one racial/ethnic group or in meta-analysis. …”
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  8. 148

    Advances and trends of modern and contemporary research on the geology of coal-measure minerals in China by Yong QIN

    Published 2025-01-01
    “…Advances Based on textual research and the analysis of logical relations, this study generalized the advances in research on the geology of CMMs in China into four aspects. (1) Increasingly improved geological theory system of CMMs: China’s classic theoretical system of coal field geology was formed in the second half of the 20th century, and the geological theory system focusing on coals, coal-measure gas, and coal-measure critical metals has been gradually developed since the 21st century. (2) Research on the origin and genesis of coals, advancing the international coal geology: The advancements include the development of the new coal metamorphism theory, the discovery of the world's youngest soft lignite, the reveal of late-stage coalification jumps, the establishment of the ordinary organic petrology, and the comprehensive ascertainment of the formation and evolutionary mechanisms of coals. (3) The unique CMM accumulation, distribution, and metallogenic theory: The specific outcomes include the establishment of multiple sedimentary and structural coal-controlling patterns, the reveal of the fundamental framework of coal accumulation in sea areas, the identification of deposits of various coal-measure critical metals, and the determination of the division schemes for coal-controlling geotectonic units and the metallogenic zones of coal-measure critical metals, and the development of a geological theory system for coalbed methane. (4) Significant achievements in the geological surveys and assessment of special coal resources: Specifically, the methodological system for the geological prediction and assessment of special coal types and high-quality, eco-friendly, and clean coal resources has been developed, the methodological system for the resource potential assessment of tar-rich coals and underground coal gasification has been formed, and the coal resources for related purposes have been preliminarily investigated. …”
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  9. 149

    KGRDR: a deep learning model based on knowledge graph and graph regularized integration for drug repositioning by Huimin Luo, Huimin Luo, Hui Yang, Hui Yang, Ge Zhang, Ge Zhang, Jianlin Wang, Jianlin Wang, Junwei Luo, Chaokun Yan, Chaokun Yan, Chaokun Yan

    Published 2025-02-01
    “…Computational drug repositioning, serving as an effective alternative to traditional drug discovery plays a key role in optimizing drug development. …”
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  10. 150

    Machine learning potential predictor of idiopathic pulmonary fibrosis by Chenchun Ding, Quan Liao, Renjie Zuo, Shichao Zhang, Zhenzhen Guo, Junjie He, Ziwei Ye, Weibin Chen, Sunkui Ke

    Published 2025-01-01
    “…Furthermore, GSEA revealed enrichment in multiple pathways, while immune function analysis demonstrated a significant correlation between IPF onset and immune cell infiltration. …”
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  11. 151
  12. 152

    Light and dark biofilm adaptation impacts larval settlement in diverse coral species by Paul A. O’Brien, Sara C. Bell, Laura Rix, Abigail C. Turnlund, Shannon R. Kjeldsen, Nicole S. Webster, Andrew P. Negri, Muhammad A. Abdul Wahab, Inka Vanwonterghem

    Published 2025-01-01
    “…Although these taxa were generally specific to each coral species, we observed bacteria classified as Flavobacteriaceae, Rhodobacteraceae, Rhizobiaceae and Pirellulaceae to be consistently correlated with larval settlement across multiple coral species. Conclusions Our work identifies novel microbial groups that significantly influence coral larval settlement, which can be targeted for the discovery of settlement-inducing metabolites for implementation in reef restoration programs. …”
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  13. 153

    Engineering of Dihydroxy Biphenyl Dioxygenase Enzyme to Improve Its Performance In Removing PCBs: A Molecular Docking Study by Susan Yazdankhah, Alireza Zakeri, Saeed Khalili, Abolfazl Jahangiri, ZahraalSadat Hashemi, Alireza Heidari

    Published 2024-10-01
    “…Materials and Methods: The amino acid sequence of the enzyme was obtained from the UniPprot database and to check similar sequences with PSI-BLAST method, similar sequences were searched from close to distant protein species. By performing multiple alignments of PSI-BLAST sequences, 250 sequences were matched. …”
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  14. 154

    Causal relationship between immune cells and risk of heart failure: evidence from a Mendelian randomization study by Wenjing Cao, Zefu Yang, Liumei Mo, Zhenhao Liu, Jiawei Wang, Zhenhong Zhang, Kui Wang, Wei Pan

    Published 2025-01-01
    “…Sensitivity analyses were conducted to validate the strength and reliability of the MR findings.ConclusionsOur study suggests that there appears to be a causal effect between multiple immune cells on heart failure. This discovery provides a new avenue for the development of therapeutic treatments for HF and a new target for drug development.…”
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  15. 155
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  17. 157

    A Novel Stacked Model for Classification of Vocal Cord Paralysis Over Imbalanced Vocal Data by K. Jayashree Hegde, K. Manjula Shenoy, K. Devaraja

    Published 2025-01-01
    “…The aforementioned gave adequate results over the dataset of voice recordings of the vowel that either have a balanced dataset across all the classes or multiple voice pathologies are selected to bring the balance in the dataset equal to healthy subjects. …”
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  18. 158
  19. 159

    The curvilinear relationship between Framingham Steatosis Index and depression: insights from a nationwide study by Chunqi Jiang, Bo Wang, Ning Wang, Jun Wang, Yinuo Qu, Guang Zhao, Xin Zhang, Xin Zhang

    Published 2025-01-01
    “…We investigated the association between FSI and depression using a weighted multiple logistic regression model and stratified analysis. …”
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  20. 160

    Altered expression of miRNA profile in peripheral blood mononuclear cells following the third dose of inactivated COVID-19 vaccine by Guanguan Qiu, Ruoyang Zhang, Huifeng Qian, Ruoqiong Huang, Jie Xia, Ruoxi Zang, Zhenkai Le, Qiang Shu, Jianguo Xu, Guoping Zheng, Jiangmei Wang

    Published 2025-01-01
    “…Bioinformatic analysis suggested that miR-25-5p, miR-34c-3p, and miR-206 may target multiple pathways involved in immune regulation and inflammation. …”
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