Large-scale prospective serum metabolomic profiling reveals candidate predictive biomarkers for suspected preeclampsia patients by Yan Cao, Lanlan Meng, Yifei Wang, Shenglong Zhao, Yuanyuan Zheng, Rui Ran, Jie Du, Hongqiang Wu, Jiaqi Han, Zhengwen Xu, Yifan Lu, Lin Liu, Lu Chen, Jing Wang, Youran Li, Yanhong Zhai, Zhi Sun, Zheng Cao

“…Moreover, a panel of seven predictive biomarkers including 2-methyl-3-hydroxy-5-formylpyridine-4-carboxylate, gamma-glutamyl-leucine, 2-hydroxyvaleric acid, LysoPC(16:1(9Z)/0:0), PC(DiMe(13,5)/MonoMe(13,5)), ADP-D-glycero-beta-D-manno-heptose and phenylalanyl-tryptophan were identified for PE development by performing multiple statistical analysis and LASSO regression analysis. …”
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New Findings by High-Order DNS for Late Flow Transition in a Boundary Layer by Chaoqun Liu, Lin Chen, Ping Lu

“…This paper serves as a summary of new discoveries by DNS for late stages of flow transition in a boundary layer. …”
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Proposal for modifying procedures for declaring significant trends in TIMSS by Henry Isaiah Braun, Matthias von Davier, Jihang Chen

“…We augment the TOST procedure with the Benjamini–Hochberg procedure (BH-TOST) to control the False Discovery Rate , to address the problem of multiplicity. …”
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Busting the Breast Cancer with AstraZeneca’s Gefitinib by S. Chemmalar, A. R. Intan Shameha, Che Azurahanim Che Abdullah, Nor Asma Ab Razak, Loqman Mohamad Yusof, Mokrish Ajat, Kim Wei Chan, Md Zuki Abu Bakar Zakaria

“…With EGFR having four homologues: EGFR1, EGFR2, EGFR3, and EGFR4, in-depth understanding of EGFR biology led to the discovery of small-molecule inhibitors and antibodies against this receptor. …”
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From Victorian Buildings to the Victorian Built Heritage: Victorian studies and the Re-interpretation of 19th-century architecture by Isabelle Cases

“…Art history is an obvious first step, and indeed a necessary but difficult approach due to the constant reinterpretation of styles of the past and the discovery of new exotic models in the Victorian period, which resulted in the so-called Victorian architectural eclecticism. …”
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Growing Concerns on Antimicrobial Resistance – Past, Present, and Future Trends by Deepak Saxena, Richa Gwalani, Aarti Yadav, Ragini Shah

“…Antimicrobial resistance [AMR] is a global problem that affects multiple domains including healthcare, agriculture, aquaculture, and many more. …”
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Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice by José Belizário, Luiz Vieira-Cordeiro, Sylvia Enns

“…Here we outline the recent discoveries into how the necrotic cell death execution pathway is engaged in many physiological and pathological outcome based on genetic analysis of knockout mice.…”
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Racial Differences in Systemic Immune Parameters in Individuals With Lung Cancer by Mitchell S. von Itzstein, MD, Jialiang Liu, PhD, Hong Mu-Mosley, PhD, Farjana Fattah, PhD, Jason Y. Park, MD, PhD, Jeffrey A. SoRelle, MD, J. David Farrar, PhD, Mary E. Gwin, MD, David Hsiehchen, MD, Yvonne Gloria-McCutchen, Edward K. Wakeland, PhD, Suzanne Cole, MD, Sheena Bhalla, MD, Radhika Kainthla, MD, Igor Puzanov, MD, MSCI, Benjamin Switzer, DO, MHSA, MS, Gregory A. Daniels, MD, PhD, Yousef Zakharia, MD, Montaser Shaheen, MD, Jianjun Zhang, MD, PhD, Yang Xie, PhD, David E. Gerber, MD

“…Differences between Black and White patients were determined and corrected for multiple comparisons. Results: A total of 187 patients with NSCLC (Black, 19; White, 168) were included in the analysis. …”
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New Sources and Old Methods. Reconstructing and Applying the Music-Theoretical Paratext of Johann Sebastian Bach’s Compositional Pedagogy by Derek Remeš

“…Fascinatingly, many newly-rediscovered chorale books from Bach’s milieu contain multiple basses under each melody, suggesting that Bach too may have employed this technique. …”
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Single-Cell Sequencing in Cancer: Recent Applications to Immunogenomics and Multi-omics Tools by Michael C. Sierant, Jungmin Choi

“…Tumor heterogeneity, the cellular mosaic of multiple lineages arising from the process of clonal evolution, has continued to thwart multi-omics analyses using traditional bulk sequencing methods. …”
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Mineralogy, alteration, fluid inclusions microthermometry and genesis of the Cu-Au Kalateh Dasht deposit, south of Shahrood, NE Iran by Mohadeseh Eskandari, Fardin Mousivand, Maryam Sheibi, Bernd Lehmann

“…Consequently, the proximity of the Kalateh Dasht IS system to an argillic zone may indicate the presence of a profound porphyry system and offer the potential the discovery of similar deposits. …”
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Hameaux et villages paysans de la période romaine en plaine d’Alsace by Antonin Nüsslein, Pascal Flotté, Mathias Higelin, Muriel Roth-Zehner

“…Research carried out in the plain of Alsace over the past twenty years has led to the discovery of sites that were composed of several agglomerated habitation units that can be described as villages and hamlets. …”
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Development and validation of a novel artificial intelligence algorithm for precise prediction the postoperative prognosis of esophageal squamous cell carcinoma by Zichen Wang, Zhihan Xiao, Tongyu Zhang, Meiyou Lu, Hai Li, Jing Cao, Jianan Zheng, Yichan Zhou, Juncheng Dai, Cheng Wang, Liang Chen, Jing Xu

“…Given the similarities with gametogenesis, cancer/testis genes (CTGs) are acknowledged for regulation unrestrained multiplication and immune microenvironment during oncogenic processes. …”
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Angiotensin-(1-7)-Mediated Signaling in Cardiomyocytes by Enéas R. M. Gomes, Robson A. S. Santos, Silvia Guatimosim

“…The Renin-Angiotensin System (RAS) acts at multiple targets and has its synthesis machinery present in different tissues, including the heart. …”
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Genome-wide association analysis of composite sleep health scores in 413,904 individuals by Matthew O. Goodman, Tariq Faquih, Valentina Paz, Pavithra Nagarajan, Jacqueline M. Lane, Brian Spitzer, Matthew Maher, Joon Chung, Brian E. Cade, Shaun M. Purcell, Xiaofeng Zhu, Raymond Noordam, Andrew J. K. Phillips, Simon D. Kyle, Kai Spiegelhalder, Michael N. Weedon, Deborah A. Lawlor, Jerome I. Rotter, Kent D. Taylor, Carmen R. Isasi, Tamar Sofer, Hassan S. Dashti, Martin K. Rutter, Susan Redline, Richa Saxena, Heming Wang

“…The heritability of the first three SHS-PCs equals or exceeds that of SHS-ADD (SNP-h2 = 0.094), while revealing sleep-domain-specific genetic discoveries. Significant loci enrich in multiple brain tissues and in metabolic and neuronal pathways. …”
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Next-Generation Sequencing and Epigenomics Research: A Hammer in Search of Nails by Shrutii Sarda, Sridhar Hannenhalli

“…In this article, we provide a brief overview of the epigenome, the various types of epigenomic data afforded by NGS, and some of the novel discoveries yielded by the epigenomics projects. We also provide ample references for the reader to get in-depth information on these topics.…”
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Blog : un journal intime comme mémoire de soi by Nolwenn Hénaff

“…Keeping a journal has become a way of live, or to moment a moment in one’s life (Lejeune, 2006). It has multiple uses: construction of a narrative identity, marking time, liberating the self, introspection, self-control, self-support, organization of thoughts or the pleasure of writing. …”
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Modulation of miRNAs in Pulmonary Hypertension by Sudhiranjan Gupta, Li Li

“…This review provides an overview of recent discoveries on the role of miRNAs in the pathogenesis of PH and discusses the potential for miRNAs as therapeutic targets and biomarkers of PH at clinical setting.…”
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Regulation of the G1/S Transition in Hepatocytes: Involvement of the Cyclin-Dependent Kinase Cdk1 in the DNA Replication by Anne Corlu, Pascal Loyer

“…It also further confirms the well-orchestrated regulation of liver regeneration via multiple extracellular signals and pathways.…”
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Comprehensive Insights into Monkeypox (mpox): Recent Advances in Epidemiology, Diagnostic Approaches and Therapeutic Strategies by Suresh Kumar, Dhanyashri Guruparan, Kalimuthu Karuppanan, K. J. Senthil Kumar

“…Recent outbreaks of mpox in multiple countries have sparked concerns regarding altered transmission patterns and the potential for a global menace. …”
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