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spVelo: RNA velocity inference for multi-batch spatial transcriptomics data
Published 2025-08-01“…However, current methods fail to utilize the spatial information inherent in spatial transcriptomics and lack scalability in multi-batch datasets. Here, we introduce spVelo, a scalable framework for RNA velocity inference of multi-batch spatial transcriptomics data. spVelo supports several downstream applications, including uncertainty quantification, complex trajectory pattern discovery, driver marker identification, gene regulatory network inference, and temporal cell-cell communication inference. spVelo has the potential to provide deeper insights into complex tissue organization and underscore biological mechanisms based on spatially resolved patterns.…”
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IHDETBO: A Novel Optimization Method of Multi-Batch Subtasks Parallel-Hybrid Execution Cloud Service Composition for Cloud Manufacturing
Published 2019-01-01“…In this paper, a new manufacturing service composition scheme named as Multi-Batch Subtasks Parallel-Hybrid Execution Cloud Service Composition for Cloud Manufacturing (MBSPHE-CSCCM) is proposed, and such composition is one of the most difficult combination optimization problems with NP-hard complexity. …”
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scFocus: Detecting branching probabilities in single-cell data with SAC
Published 2025-01-01“…Furthermore, scFocus is applied to ten single-cell datasets, including small-scale datasets, common-scale datasets, and multi-batch datasets. This demonstrates its applicability on different types of datasets and showcases its potential in discovering biological changes due to experimental treatments through multi-batch dataset processing. …”
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Partially characterized topology guides reliable anchor-free scRNA-integration
Published 2025-04-01“…To address this, we propose scCRAFT, an autoencoder model that separates cell-type-related signals from batch effects for reliable multi-batch integration. scCRAFT integrates three key loss components: a reconstruction loss for observation reconstruction, a multi-domain adaptation loss to eliminate batch effects, and an innovative dual-resolution triplet loss to preserve intra-batch, introduced as an effective mechanism to counteract the over-correction effect of domain adaptation loss amid heterogeneous cell distributions across batches. …”
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Modeling and Optimization of Cable Production Scheduling by Incorporating an Ant Colony Algorithm
Published 2025-04-01“…With the development of small batch and multi-batch service production mode, manual scheduling by hand has been difficult to adapt to the production of a large number of complex orders. …”
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AML-Based Multi-Dimensional Co-Evolution Approach Supported by Blockchain: Architecture Design and Case Study on Intelligent Production Lines for Industry 4.0
Published 2025-03-01“…Its innovations are, firstly, developing a comprehensive two-layer management model, combining blockchain with the Interplanetary File System (IPFS) to build an integrated solution for private and public hybrid containers based on a collaborative model; secondly, designing a version co-evolution management method by combining smart contract workflows and AML multi-dimensional modeling processes; meanwhile, introducing a specially designed conflict resolution mechanism based on the graph model to maintain consistency in version multi-batch management and; finally, using the test cases established in the lab’s I5Blocks for verification.…”
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scRDEN: single-cell dynamic gene rank differential expression network and robust trajectory inference
Published 2025-05-01“…This outstanding performance provides novel and valuable insights into large-scale, multi-batch trajectory inference and the study of transcriptional mechanism regulation during the processes of differentiation and development.…”
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micRoclean: an R package for decontaminating low-biomass 16S-rRNA microbiome data
Published 2025-05-01“…Further, we demonstrate through a multi-batch simulated microbiome sample that micRoclean matches or outperforms tools with similar objectives. …”
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