Safety Effects of Connected and Automated Vehicle-Based Variable Speed Limit Control near Freeway Bottlenecks considering Driver’s Heterogeneity by Ye Li, Yuntao Shi, Jaeyoung Lee, Chen Yuan, Baojie Wang

“…The results indicate the following: (1) the heterogeneity of human drivers negatively affects the performance of the VSL; (2) the performance of the proposed control system in a mixed flow can be improved by advanced wireless communication technology; (3) CAVs are able to implement the VSL control strategy effectively resulting in the proactive reduction of the heterogeneity.…”
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Agomelatine as adjunctive therapy with SSRIs or SNRIs for major depressive disorder: a multicentre, double-blind, randomized, placebo-controlled trial by Yumeng Ju, Wenwen Ou, Haoran Chen, Limin Yang, Yan Long, Hui Liang, Zhenman Xi, Mei Huang, Wentao Chen, Guanyi Lv, Fangzhou Shao, Bangshan Liu, Jin Liu, Zexuan Li, Mei Liao, Weiye Liang, Zhijian Yao, Yan Zhang, Lingjiang Li

“…Adverse events (AEs) reported in both groups were recorded. A linear mixed model was established for both primary and secondary outcomes. …”
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Interferon Regulatory Factor 4 dose-dependently controls peripheral Treg cell differentiation and homeostasis by modulating chromatin accessibility in mice by Leonie Caroline Voß, Constantin Schmidt, Constantin Schmidt, Aenne Harberts, Aenne Harberts, Aenne Harberts, Michael Spohn, Michael Spohn, Michael Spohn, Peter Bradtke, Alina Borchers, Alina Borchers, Alina Borchers, Stefanie Fertig, Joanna Schmid, Friedrich Koch-Nolte, Christian F. Krebs, Christian F. Krebs, Christian F. Krebs, Friederike Raczkowski, Hans-Willi Mittrücker, Hans-Willi Mittrücker

“…Here, we analyze the role of IRF4 in differentiation and maintenance of Treg cells using IRF4-deficient mice and a T cell transfer model, that allows Irf4 inactivation in peripheral T cells. …”
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Low‐Magnitude High‐Frequency Vibration Attenuates Sarcopenia by Modulating Mitochondrial Quality Control via Inhibiting miR‐378 by Yu‐Feng Long, Can Cui, Qianjin Wang, Zhen Xu, Simon Kwoon‐Ho Chow, Ning Zhang, Ronald Man Yeung Wong, Elvis Chun‐Sing Chui, Rebecca Schoenmehl, Christoph Brochhausen, Clinton Rubin, Gang Li, Ling Qin, Da‐Zhi Yang, Wing‐Hoi Cheung

“…Subsequently, we evaluated the effect of LMHFV on miR‐378 using both mouse models. Results Reduction in muscle strength was observed from the ages of month 8 to 10 in SAMP8 mice (grip strength decreased 27.1%, p = 0.0263; twitch force decreased 29.1%, p = 0.0178; tetanic force decreased 29.9%, p = 0.011), as well as muscle atrophy (cross‐section area: 38.3%, p = 0.0121). …”
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Risk Assessment of <i>Brucella</i> Exposure Through Raw Milk Consumption in India: One Health Implications and Control Strategies by Vijay Sharma, Balbir B. Singh, Victoria J. Brookes

“…Samples from lactating cattle and buffalo (N = 261) in ten villages were tested using the Rose Bengal plate test and indirect IgG ELISA. Modelled risk pathways estimated <i>B. abortus</i> shedding probabilities and colony-forming unit (CFU) concentrations in milk, with Sobol sensitivity analysis identifying influential parameters. …”
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Effect of Physical Activity and Dietary Changes on Management of Type 2 Diabetes Mellitus Patients: A Case–Control Study in Bangladesh by Hasan Mahmud Hadi, Md. Monir Hossain Shimul, Md. Sakhawath Hossain, Afroza Sultana, Md. Kamrul Hossain, Salamat Khandker, Salim Khan

“…Chi‐square tests and ordinal logistic regression models assessed associations between lifestyle factors and glycaemic outcomes. …”
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Patterns and predictors of smokeless tobacco use among adults in Bangladesh: findings from the International Tobacco Control (ITC) Bangladesh survey. by Abu S Abdullah, Pete Driezen, Ummul H Ruthbah, Nigar Nargis, Anne C K Quah, Geoffrey T Fong

“…We used multiple logistic regression models to identify predictors of SLT use.<h4>Results</h4>Of the respondents (N = 5522), 20% were SLT users. …”
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Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients. by Cynthia Sung, Yuan Wei, Satoru Watanabe, How Sung Lee, Yok Moi Khoo, Lu Fan, Abhay P S Rathore, Kitti Wing-Ki Chan, Milly M Choy, Uma S Kamaraj, October M Sessions, Pauline Aw, Paola F de Sessions, Bernett Lee, John E Connolly, Martin L Hibberd, Dhanasekaran Vijaykrishna, Limin Wijaya, Eng Eong Ooi, Jenny Guek-Hong Low, Subhash G Vasudevan

“…<h4>Unlabelled</h4>CELADEN was a randomized placebo-controlled trial of 50 patients with confirmed dengue fever to evaluate the efficacy and safety of celgosivir (A study registered at ClinicalTrials.gov, number NCT01619969). …”
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Evaluating the Effectiveness of an Intelligent mHealth Intervention for Child Unintentional Injury Prevention: Protocol for a Cluster Randomized Controlled Trial by Yang Yuan, Yuying Jing, Jiyu Li, Jieyi He, David C Schwebel, Peishan Ning, Zhenzhen Rao, Li Li, Guoqing Hu

“…MethodsA double-blind, 12-month follow-up, cluster randomized controlled trial will be implemented in Changsha, Hunan Province, China. …”
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Randomized, Placebo‐Controlled, Triple‐Blind Clinical Trial of Ivabradine for the Prevention of Cardiac Dysfunction During Anthracycline‐Based Cancer Therapy by Stephanie Itala Rizk, Isabela Bispo Santos da Silva Costa, Cecília Beatriz Bittencourt Viana Cruz, Brunna Pileggi, Fernanda Thereza de Almeida Andrade, Thalita Barbosa Gonzalez, Cristina Salvadori Bittar, Julia Tizue Fukushima, Vinicius Caldeira Quintao, Eduardo Atsushi Osawa, Juliana Barbosa Sobral Alves, Silvia Moulin Ribeiro Fonseca, Diego Ribeiro Garcia, Juliana Pereira, Valeria Buccheri, Juliana Avila, Lucas Tokio Kawahara, Cecilia Chie Sakaguchi Barros, Lucas Takeshi Ikeoka, Letícia Naomi Nakada, Mariella Fellini, Vanderson Geraldo Rocha, Eduardo Magalhães Rego, Paulo Marcelo Gehm Hoff, Roberto Kalil Filho, Giovanni Landoni, Ludhmila Abrahão Hajjar

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Exercise into Pain in Chronic Rotator Cuff-Related Shoulder Pain: A Randomized Controlled Trial with 6-Month Follow-Up by Cavaggion C, Luque-Suarez A, Voogt L, Juul-Kristensen B, Wollants G, Beke L, Fransen E, Struyf F

“…The objective of this study was to investigate if exercise into pain is more effective than no pain in RCRSP.Patients and Methods: A randomized controlled trial was conducted in a physiotherapy clinic in Belgium. …”
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Redox regulation and dynamic control of brain-selective kinases BRSK1/2 in the AMPK family through cysteine-based mechanisms by George N Bendzunas, Dominic P Byrne, Safal Shrestha, Leonard A Daly, Sally O Oswald, Samiksha Katiyar, Aarya Venkat, Wayland Yeung, Claire E Eyers, Patrick A Eyers, Natarajan Kannan

“…Consistently, mutation of the CPE-Cys increases catalytic activity in vitro and drives phosphorylation of the BRSK substrate Tau in cells. Molecular modeling and molecular dynamics simulations indicate that oxidation of the CPE-Cys destabilizes a conserved salt bridge network critical for allosteric activation. …”
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Resistance exercise training improves disuse-induced skeletal muscle atrophy in humans: a meta-analysis of randomized controlled trials by Xian Guo, Yanbing Zhou, Xinxin Li, Jinhao Mu

“…Data were pooled using random-effects models. Results Eleven randomized controlled trials were finally included. …”
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Analysis and research of industrial value chain optimization model based on energy internet environment by Shaoyang Yin, Xiaohua Yang, Qi Xu, Guangjie Liu

“…Furthermore, it is anticipated that this approach will potentially lead to a further 10% improvement in energy efficiency and a reduction of 15% in operational costs. In addition, this study also combines the actual cases of many industries to verify the optimization model. …”
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Culturally Adapted Guided Internet-Based Cognitive Behavioral Therapy for Hong Kong People With Depressive Symptoms: Randomized Controlled Trial by Jia-Yan Pan, Jonas Rafi

“…Data analysis was conducted using linear mixed effects modeling, adhering to the intent-to-treat principle. …”
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An Algorithm for Simplifying 3D Building Models with Consideration for Detailed Features and Topological Structure by Zhenglin Li, Zhanjie Zhao, Wujun Gao, Li Jiao

“…It incorporates the centroid displacement of the simplification unit, significance level, and approximate curvature of the edge as influencing factors for the collapse cost to control the edge collapse sequence and preserve model details. …”
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Towards a finite element model of a batch of experimental violins: validation on sub-structural components by Meza-Pérez Amaury, Stoppani George, Viala Romain, Gonzalez Sebastian, Igartua Unai, Jardón Rico Roberto, Fritz Claudia

“…The proposed approach enables the identification of material properties in multiple directions and ensures a step-by-step control of the accuracy of the modeled parts compared to the real ones.…”
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Urban pertussis epidemiological patterns in a highly vaccinated megacity: Policy impacts and control strategies in Chongqing, China, 2005-2024 by Rui Shen, Jiawei Xu, Yugang Li, Jianxing Yu, Na Sun, Zilu Xu, Xueying Xu, Xiao Liu, Yang Liu, Bosong Li, Li Qi, Luzhao Feng

“…Molecular diagnostics implementation revealed substantial hidden transmission (RR: 82.65, 95% CI: 73.47-92.99). Modeling projected extended school-age boosters (ages 5-7 years) would reduce incidence by 47.93%, targeted vaccination of ages 6-7 years achieved 36.64% reduction, and the national benchmark with 6-year booster reduced incidence by 19.09%. …”
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Effects of home-based integrated sensory stimulation program to preterm infants on parents’ depression and anxiety: a randomized controlled trial by Wenjing Zheng, Rassamee Chotipanvithayakul, Thammasin Ingviya, Fang Guo

“…In the mixed linear model, the intervention was associated with reductions in maternal trait anxiety (d =-2.18; 95% CI: −4.30, −0.06), paternal trait anxiety (d =-3.37; 95% CI: −5.62, −1.11) and state anxiety (d =-4.63; 95% CI: −7.00, −2.26). …”
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Modelling the environmental impact of sesame production under different fertilizer and water use regimes by Nasser Nourzadeh, Asghar Rahimi, Amir Dadrasi

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