Comparative duration of neutralizing responses and protections of COVID-19 vaccination and correlates of protection by Chang Liu, Tim K. Tsang, Sheena G. Sullivan, Benjamin J. Cowling, Bingyi Yang

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The association between ozone exposure and blood pressure in a general Chinese middle-aged and older population: a large-scale repeated-measurement study by Chen Tang, Yiqin Zhang, Jingping Yi, Zhonghua Lu, Xianfa Xuan, Hanxiang Jiang, Dongbei Guo, Hanyu Xiang, Ting Wu, Jianhua Yan, Siyu Zhang, Yuxin Wang, Jie Zhang

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Development mechanism and practical significance of deep coalbed methane (coal rock gas) infiltration and displacement by Lihong ZHOU, Xia YAN, Hongtao LIU, Xianyue XIONG, Feng WANG, Shuguang LI, Jiyuan ZHANG, Chuanqing LIU, Xiong HU, Pu YUAN, Qianli MA, Xueguang ZHU

“…Methane adsorption reduction: Isothermal adsorption experiments and HTHP NMR scans demonstrated that fracturing fluids significantly weaken methane-coal interactions. …”
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Altered Intestinal Microbiota with Increased Abundance of Prevotella Is Associated with High Risk of Diarrhea-Predominant Irritable Bowel Syndrome by Tingting Su, Rongbei Liu, Allen Lee, Yanqin Long, Lijun Du, Sanchuan Lai, Xueqin Chen, Lan Wang, Jianmin Si, Chung Owyang, Shujie Chen

“…Animal models similarly showed an increased abundance of Prevotella in fecal samples compared with control mice (p<0.05). …”
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The Olive Oil Monophenolic Secoiridoid Ligstroside Aglycone Suppresses Melanoma Progression by Targeting the BRAF Signaling Pathway by Md Ashiq Mahmud, Abu Bakar Siddique, Afsana Tajmim, Judy Ann King, Khalid A. El Sayed

“…These findings promote LA as a potential nutraceutical lead for the control of the <i>BRAF V600E</i> mutant melanoma.…”
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Significant Inhibition of Tumor Growth following Single Dose Nanoparticle-Enhanced Photodynamic Therapy by Shih-Hsun Cheng, Chia-Hui Chu, Nai-Tzu Chen, Jeffrey S. Souris, Chin-Tu Chen, Leu-Wei Lo

“…In the current work, we report on the in vivo assessment of PDT efficacy of these nanoconstructs in a murine model of human breast cancer, following a single (one-shot) nanoparticle dose and photoirradiation. …”
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Life Cycle Assessment of Land Use Trade-Offs in Indoor Vertical Farming by Ana C. Cavallo, Michael Parkes, Ricardo F. M. Teixeira, Serena Righi

“…A Life Cycle Assessment (LCA) was conducted using the Environmental Footprint (EF) method and the LANCA model to account for land use and soil-related impacts. …”
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Comprehensive assessment of air pollutant emissions, climate scenario projections, and mitigation strategies in Iran by Saeed Sharafi, Maryam Lorvand

“…Focusing on key greenhouse gases (CO2 and CH4) and air pollutants (NO2 and SO2), the research employs Shared Socioeconomic Pathways (SSPs), Representative Concentration Pathways (RCPs), and the innovative Pattern Mining Engine (PME) model. Covering the period from 1960 to 2100, the study identifies pivotal trends and key change points in emission trajectories. …”
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A Biomechanical Evaluation of a Novel Interspinous Process Device: In Vitro Flexibility Assessment and Finite Element Analysis by Hangkai Shen, Chuanguang Ju, Tao Gao, Jia Zhu, Weiqiang Liu

“…A validated L1–L5 finite element model was subsequently employed to assess biomechanical responses under both static and vertical vibration loading regimes. …”
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Remote-Management of COPD: Evaluating the Implementation of Digital Innovation to Enable Routine Care (RECEIVER): the protocol for a feasibility and service adoption observational... by David J Lowe, Grace McDowell, Anna Taylor, Stephanie Lua, Shane Burns, Paul McGinness, Christopher M Carlin

“…Introduction Reductions in exacerbation and hospitalisations are the outcomes rated as most important by people with chronic obstructive pulmonary disease (COPD). …”
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Combined loss of brevican, neurocan, tenascin-C and tenascin-R leads to impaired fear retrieval due to perineuronal net loss by Cornelius Mueller-Buehl, Johanna Pakusch, Verian Bader, Konstanze F. Winklhofer, Melanie D. Mark, Andreas Faissner

“…In contrast, tenascin single KOs showed intact fear behavior and memory compared to their control groups. Impaired fear memory consolidation can be advantageous in certain conditions, such as PTSD, making the 4x KO mice an intriguing model for future fear conditioning studies and highlighting brevican, neurocan, Tnc, and Tnr as compelling targets for further investigation. …”
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Avatar Intervention in Virtual Reality for Cannabis Use Disorder in Individuals With Severe Mental Disorders: Results From a 1-Year, Single-Arm Clinical Trial by Sabrina Giguere, Mélissa Beaudoin, Laura Dellazizzo, Kingsada Phraxayavong, Stéphane Potvin, Alexandre Dumais

“…Changes in reported outcomes during the assessment periods before the intervention; postintervention; and 3, 6, and 12 months after the end of the intervention were assessed using a linear mixed-effects model. ResultsSignificant reductions were observed in the quantity of cannabis consumed, and these were maintained until the 12-month follow-up visit (dPdP ConclusionsOverall, this unique intervention shows promising results that seem to be maintained up to 12 months after the end of the intervention. …”
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Influence of NG-nitro-L-arginine methyl ester on clinical and biochemical effects of methylene blue in pentylenetetrazole-evoked convulsions by Jelenković Ankica, Jovanović Marina D., Bokonjić Dubravko, Maksimović Milan, Bošković Bogdan

“…Despite years of research in a number of experimental models the question whether nitric oxide (NO) and methylene blue (MB) have pro- or anticonvulsant effects remains to be fully resolved. …”
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Association of Dipeptidyl Peptidase-4 Inhibitors with Glaucoma Risk in Patients with Type 2 Diabetes: A Nationwide Cohort Study by Yi-An Lu, MD, Peng-Tai Tien, MD, PhD, Yih-Dih Cheng, PhD, Yow-Wen Hsieh, PhD, Der-Yang Cho, MD, Shang-Feng Tsai, MD, PhD, Chien-Hsiang Weng, MD, MPH, Heng-Jun Lin, Hui-Ju Lin, MD, PhD, I-Jong Wang, MD, PhD, Chien-Chih Chou, MD, PhD

“…Cox proportional hazards models were applied to estimate hazard ratios for POAG and NTG, adjusting for age, sex, comorbidities, and concurrent antidiabetic medications. …”
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Exploring the anti-inflammatory effects of Lavandula stoechas L. extract on ovalbumin-induced acute asthma in BALB/c mice by Nafiseh Erfanian, Faezeh Fazlpour, Hossein Safarpour, Sayyedeh Fatemeh Askari, Mohsen Foadoddini, Saeed Nasseri

“…In this study, we aimed to explore the anti-inflammatory effects of the hydro-alcoholic extract of L. stoechas in a mice model of acute asthma.Materials and Methods: Thirty-five male BALB/c mice were placed into five distinct study groups: (1) control, (2) ovalbumin (OVA) + Al(OH)3, (3) OVA + L. stoechas (200 mg/kg), (4) OVA + L. stoechas (300 mg/kg) and (5) OVA + dexamethasone. …”
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Pancreatic Safety of Tirzepatide and Its Effects on Islet Cell Function: A Systematic Review and Meta‐Analysis by A. B. M. Kamrul‐Hasan, Sunetra Mondal, Deep Dutta, Lakshmi Nagendra, Mohammed Ruhul Kabir, Joseph M. Pappachan

“…Methods Electronic databases were searched for RCTs with tirzepatide as the intervention and a placebo or active comparator as the control. The primary outcome was adjudication‐confirmed pancreatitis; secondary outcomes were the percent changes from baseline in serum pancreatic amylase, lipase, insulin, C‐peptide, glucagon, and homeostasis model assessment of insulin resistance (HOMA2‐IR). …”
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Impact of contact tracing on COVID-19 mortality: An impact evaluation using surveillance data from Colombia. by Andres I Vecino-Ortiz, Juliana Villanueva Congote, Silvana Zapata Bedoya, Zulma M Cucunuba

“…Both the proportion of cases identified through contact tracing and the daily number of COVID-19 deaths are smoothed using 7-day moving averages. Models control for the prevalence of active cases, second-degree polynomials, and mobility indices. …”
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Immunization with SARS coronavirus vaccines leads to pulmonary immunopathology on challenge with the SARS virus. by Chien-Te Tseng, Elena Sbrana, Naoko Iwata-Yoshikawa, Patrick C Newman, Tania Garron, Robert L Atmar, Clarence J Peters, Robert B Couch

“…<h4>Design</h4>Four candidate vaccines for humans with or without alum adjuvant were evaluated in a mouse model of SARS, a VLP vaccine, the vaccine given to ferrets and NHP, another whole virus vaccine and an rDNA-produced S protein. …”
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Reduced circulating NrCAM as a biomarker for fetal growth restrictionResearch in context by Lucy A. Bartho, Susan P. Walker, Danica Idzes, Alexander E.P. Heazell, Lucy E. Higgins, Amanda N. Sferruzzi-Perri, Natalie J. Hannan, Catherine A. Cluver, Lina Bergman, Georgia P. Wong, Manju Kandel, Ping Cannon, Tuong-Vi Nguyen, Anna Nguyen, Stephen Tong, Tu'uhevaha J. Kaitu'u-Lino

“…The effect of hypoxia on NrCAM expression was measured in trophoblast stem cells, primary trophoblasts, and a murine FGR model. Findings: Circulating NrCAM was reduced at 36 weeks’ gestation in women who later delivered FGR infants (p = 4.75 x 10−6, AUC = 0.76, n = 26 FGR, n = 957 controls). …”
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Five-year Variations in Air Pollutant Emissions with Ultra-low Emission Retrofits in a 660 MW Coal-fired Power Unit by Zhiyong Li, Zhuangzhuang Ren, Chengjing Cao, Chen Liu, Zhen Zhai, Jixiang Liu, Ziyi Zhan, Changtao Huang, Lan Chen, Hongdan Yuan

“…It was particularly pointed out that emissions increased again in 2017 though they still met the ULE standards, indicating the comprehensive consideration should be taken between the emission reductions and high cost of the ULE policy. What’s more, the ULE transformation weaken the correlation between pollutant emissions (in mg m−3) and corresponding removal efficiencies of control devices, evidencing the pollutant emissions received complex impacts from coal components, emission control technologies and devices, and so on. …”
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