Coevolution of the Ile1,016 and Cys1,534 Mutations in the Voltage Gated Sodium Channel Gene of Aedes aegypti in Mexico. by Farah Z Vera-Maloof, Karla Saavedra-Rodriguez, Armando E Elizondo-Quiroga, Saul Lozano-Fuentes, William C Black Iv

“…Currently 2.5 billion people are at risk for infection and reduction of Ae. aegypti populations is the most effective means to reduce the risk of transmission. …”
Get full text

Optimized Water Management Strategies: Evaluating Limited-Irrigation Effects on Spring Wheat Productivity and Grain Nutritional Composition in Arid Agroecosystems by Zhiwei Zhao, Qi Li, Fan Xia, Peng Zhang, Shuiyuan Hao, Shijun Sun, Chao Cui, Yongping Zhang

“…Strong correlations emerged between protein composition and processing quality, while regression modeling identified an optimal water consumption threshold (3250~3500 m³ ha⁻¹) that concurrently maximized grain yield, protein output, and WUE. …”
Get full text

Dose–response study of a fenugreek-based antibiotic alternative in Bábolna Tetra-SL chicks (1–42 days old) with mixed bacterial infections by Ádám Kerek, Ádám Kerek, Ábel Szabó, Péter Ferenc Dobra, Krisztina Bárdos, Krisztina Bárdos, Bettina Paszerbovics, Zsófia Bata, Viviána Molnár-Nagy, Ákos Jerzsele, Ákos Jerzsele, László Ózsvári, László Ózsvári

“…Additionally, the 1 × dose group showed significantly reduced Salmonella shedding compared to the positive control group on day 33 (p = 0.0031). The low-dose group (1×) demonstrated the most promising results, showing a 63% reduction in Salmonella shedding on day 10 and 31% on day 17. …”
Get full text

Association of serum 25-hydroxyvitamin D with the risk of depression in individuals with prediabetes and diabetes: A prospective cohort study by Huaxue Li, Guodong Liu, Yicheng Ma, Yingzhou Shi, Junming Han, Shengyu Tian, Hang Dong, Peipei Wang, Yingli Lu, Qiang Wang, Ling Gao, Yiping Cheng

Get full text

Simulated annealing optimization on multi-chamber mufflers hybridized with perforated plug-inlet under space constraints by Mi Chie CHIU

Get full text

Dynamic calibration of low-cost PM2.5 sensors using trust-based consensus mechanisms by Sachit Mahajan, Dirk Helbing

“…High-trust sensors receive minimal correction, preserving baseline accuracy, while low-trust sensors leverage expanded wavelet-based features and deeper models. Results show mean absolute error (MAE) reductions of up to 68% for poorly performing sensors and 35–38% for reliable ones, outperforming conventional calibration methods. …”
Get full text

Research on the Characteristics of a Range-Extended Hydraulic–Electric Hybrid Drive System for Tractor Traveling Systems by Hanwen Wu, Long Quan, Yunxiao Hao, Zhijie Pan, Songtao Xie

“…By combining the high-torque characteristics of hydraulic drive systems with the high control precision of electric motors, a hydraulic–electric dual-power coupling model was constructed. …”
Get full text

SMAD4 promotes EMT in COPD airway remodeling induced by cigarette smoke through interaction with O-GlcNAc transferase by Ziteng Wang, Yu Ding, Pei Wang, Jinyan Yu, Shulun Huang, Lingjia Yang, Hongjing Gong, Zhen Yu, Rongguo Lu, Tao Bian, Yan Wu

“…In our research, we observed a substantial upregulation in SMAD4 expression, O-GlcNAcylation and EMT in patients with COPD, as well as in vitro and in vivo COPD models induced by CS, than those of the controls. …”
Get full text

Construction and functional identification of overexpression vector of the peach PpCLH1 gene by LIU Xin, ZHANG Xiaoyu, MENG Junren, LI Ang, DUAN Wenyi, SUN Shihang, PAN Lei, ZENG Wenfang, WANG Zhiqiang, NIU Liang

“…The phenotypic evaluation of transfected tobacco leaves displayed a lighter green phenotype relative to the dark green control leaves, accompanied by a substantial reduction in chlorophyll content. …”
Get full text

Association between dietary selenium intake and endometriosis risk: a cross-sectional analysis by Jia-Jie Guo, Jia-Jie Guo, Jia-Jie Guo, Jia-Jie Guo, Jia-Jie Guo, Rui-Xuan Li, Rui-Xuan Li, Rui-Xuan Li, Rui-Xuan Li, Rui-Xuan Li, Wen-Li Shang, Wen-Li Shang, Wen-Li Shang, Wen-Li Shang, Wen-Li Shang, Ya-Fang Zheng, Ya-Fang Zheng, Ya-Fang Zheng, Ya-Fang Zheng, Ya-Fang Zheng, Guo-Yi Zhu, Guo-Yi Zhu, Guo-Yi Zhu, Guo-Yi Zhu, Guo-Yi Zhu, Zhou-Chang Shu, Zhou-Chang Shu, Zhou-Chang Shu, Zhou-Chang Shu, Zhou-Chang Shu, Gui-Chao Liu, Gui-Chao Liu, Gui-Chao Liu, Gui-Chao Liu, Gui-Chao Liu, Hong-Biao Ou, Hong-Biao Ou, Hong-Biao Ou, Hong-Biao Ou, Hong-Biao Ou, Jia-Ying Li, Jia-Ying Li, Jia-Ying Li, Jia-Ying Li, Jia-Ying Li, Xu-Guang Guo, Xu-Guang Guo, Xu-Guang Guo, Xu-Guang Guo, Li-Hong Lin, Li-Hong Lin, Li-Hong Lin, Li-Hong Lin, Li-Hong Lin

“…In the highest dietary selenium intake group, the adjusted model II revealed a reduction in the risk of EMs by approximately 34.1% (OR = 0.659, 95% CI: 0.449, 0.967). …”
Get full text

Comparative analysis of the effectiveness of BPG, AGU, AVIF and HEIF compression methods for medical images corrupted by noise of two types by Viktoriia Naumenko, Volodymyr Lukin, Vitalii Naumenko, Nadiia Kozhemiakina, Mykyta Solodovnyk

“…The scientific novelty of the obtained results includes: 1) The consideration of noise models and parameter levels typical for medical imaging, namely, additive Gaussian noise of such intensity that it approximately corresponds to just noticeable differences, and signal-dependent Poisson noise; 2) The analysis of the multi-scale structural similarity index (MS-SSIM), which has not been previously explored in studies on lossy compression of noisy medical images; 3) A detailed examination of AVIF and HEIF coders to determine whether the optimal operating point (OOP) is observed for them and under which noise conditions; 4) The use of a dataset comprising ten medical images of varying visual complexity, with generalized tendencies revealed for different structural types; 5) The identification of the ability of many metrics to exhibit an OOP for images of moderate visual complexity or those dominated by homogeneous areas; 6) For Poisson noise, the demonstration of a dependence between the quality factor Q in the OOP and the average image intensity, which can be practically estimated for a given image; 7) The finding that different encoders require different approaches to determine their respective OOPs due to their distinct compression control parameters; 8) The observation that compression ratios achieved at the OOP are generally high, supporting the feasibility of using the OOP or its neighbourhood in practice.…”
Get full text

Tuberculosis incidence among children under five years of age in Mozambique: Spatial distribution and predictors in a nationwide Bayesian disease mapping study by Nelson Cuboia, Marla Amaro, Ivan Manhiça, Joana Reis-Pardal, Pereira Zindoga, Isabel Pfumo-Cuboia, Benedita José, Claúdia Mutaquiha, Luís Nitrogénio, Aleny Couto, Luís Azevedo

Get full text

Mechanism and quantitative traceability of anomalous outflow of unloaded gas from protective layer mining under complex tectonics by Xuexi CHEN, Xingyu CHEN, Jiaying HU, Aitao ZHOU, Jian XIAO, Jihong SUN, Zhilong YAN

“…Protective layer mining is an effective technical means for the prevention and control of gas disasters. The issue of abnormal water inrush during the mining process is a significant threat to the safe production of mines. …”
Get full text

Effects of different types of fruit bags on peel color and fruit quality in Zijinhong No. 2 peach by YOU Shuanghong, SHI Wenjing, CHEN Yuanping, WEI Zhaoxin, ZHOU Guangwen, LIU Jiahong, YAN Chongxi, HAN Guohui

“…In contrast, treatment Ⅳ led to a 3.30% reduction in single fruit mass, but the difference was still not significant. …”
Get full text

Myocardial Blood Flow and the Retinal Microvasculature Across the Spectrum From Normal to Failing Hearts by Jia Liu, Chang Chen, Zhongping Yu, Xuwei Chen, Zihao Chen, Wei Li, Min Ye, Xin He, Jiangui He, Juping Liu, Yugang Dong, Jan A. Staessen, Chen Liu, Fengjuan Yao, Fang‐Fei Wei

“…We aimed to investigate the association of myocardial blood flow (MBF) and the retinal microvasculature with left ventricular (LV) function and its potential mediators. In healthy controls (HCs; n = 48), patients with cardiovascular risk factors (CVRF; n = 49) and patients with compensated HF (CHF; n = 52), we assessed LV diastolic filling pressure (E/e′), LV ejection fraction (LVEF), and global longitudinal strain (GLS) associated with MBF and the retinal arteriole‐to‐venule ratio (AVR), using multivariable regression models, while considering their direct contributions to LV function and the indirect contributions running via NT‐proBNP. …”
Get full text

Efficacy of TIPS plus extrahepatic collateral embolisation in real-world data: a validation study by Chao Chen, Feng Zhang, Hao Wu, Wei Wu, Hui Xue, Yuzheng Zhuge, Chunqing Zhang, Guangchuan Wang, Zhengjie Li, Qiong Wu, Bo Wei, Jun Tie, Xiubin Sun, Lianhui Zhao, Yifu Xia, Jiao Xu, Peijie Li

“…Additionally, the random forest models showed higher accuracy and AUROC comparing to other models. …”
Get full text

Variations in Rural PM2.5 Sources and Composition in the Post Coal-to-Gas Period Based on a Three-Year Observation by Zhi Ning, Zhiyong Li, Jihong Wei, Jinming Liu, Huichun Ma, Zhuangzhuang Ren, Xiaohua Ma, Chen Liu, Lan Chen, Aiqin Liu, Binglin Wang, Jiaqi Wang, Huiying Gao

“…However, the continuity of CTG effectiveness on PM2.5 control in the post CTG remained unclear, especially in rural area, retarding the further emission-control policy optimization. …”
Get full text

Population impact and effectiveness of sequential 13-valent pneumococcal conjugate and monovalent rotavirus vaccine introduction on infant mortality: prospective birth cohort studi... by Anthony Costello, Neil French, Charles Mwansambo, Ellen Heinsbroek, Naor Bar-Zeev, Amelia Crampin, Nigel Cunliffe, Sonia Lewycka, Carina King, James Beard, Tambosi Phiri, Hazzie Mvula, Dan Hungerford, Jennifer Verani, Cynthia Whitney, Rob Heyderman, Osamu Nakagomi, Jacqueline E Tate, Umesh D Parashar

Get full text

MAPT-A152T mutation drives neuronal hyperactivity through Fyn-NMDAR signaling in human iPSC-Derived neurons: Insights into Alzheimer's pathogenesis by Maika Itsuno, Hirokazu Tanabe, Etsuko Sano, Takashi Sasaki, Chisato Oyama, Hiroko Bannai, Koichi Saito, Kazuhiko Nakata, Setsu Endoh-Yamagami, Hideyuki Okano, Sumihiro Maeda

“…Inhibition of NMDA receptors (NMDAR) and the reduction of tau protein levels decreased neuronal excitability in both A152T/A152T and healthy control (WT/WT) excitatory neurons. …”
Get full text

Corporate Governance Code and Earnings Management by Azam Valizadeh Iarijani, Reyhaneh Iranpour

“…It has had a significant negative effect and has led to the reduction of managers' opportunistic manipulations. …”
Get full text