One year of high-frequency monitoring of groundwater physico-chemical parameters in the Weierbach experimental catchment, Luxembourg by K. N. van Zweel, K. N. van Zweel, L. Gourdol, J. F. Iffly, L. Léonard, F. Barnich, L. Pfister, E. Zehe, C. Hissler

“…</p> <p>Through rigorous data collection and quality control, parameters such as electrical conductivity, dissolved oxygen, oxidation–reduction potential, and pH were measured, providing insights into the CZ's hydrological and biogeochemical dynamics. …”
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Indoximod Attenuates Inflammatory Responses in Acetic Acid-Induced Acute Colitis by Modulating Toll-like Receptor 4 (TLR4) Signaling and Proinflammatory Cytokines in Rats by Gulcin Ercan, Hatice Aygun, Ahmet Akbaş, Osman Sezer Çınaroğlu, Oytun Erbas

“…<i>Results:</i> Acetic acid-induced colitis significantly increased mucosal damage, TLR4 expression, and circulating levels of TNF-α, PTX-3, and PAF compared with controls (<i>p</i> < 0.001). Indoximod treatment markedly reduced histological injury and significantly suppressed TLR4 and TNF-α levels (<i>p</i> < 0.01), along with partial reductions in PTX-3 (<i>p</i> < 0.05). …”
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Reverse transcriptase inhibitors diminish systemic proinflammatory responses to bacterial pathogens by Karthik Hullahalli, Katherine G. Dailey, Ryan Acbay, Masataka Suzuki, George I. Balazs, Matthew K. Waldor

“…Here we demonstrate that treatment of mice with reverse transcriptase inhibitors leads to broad reductions in systemic proinflammatory responses during bacterial infections and can protect mice from acute death in a lethal model of sepsis. …”
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Optimizing seasonal performance of advanced heat mitigation solutions for city-scale thermal management in Greater Kuala Lumpur by Norishahaini Mohamed Ishak, Ansar Khan, Jamalunlaili Abdullah, Siti Aekbal Salleh, Mattheos Santamouris

“…We assess city-scale thermal management through high-resolution numerical simulations using the weather research and forecasting (WRF) model coupled with the single-layer urban canopy model (SLUCM), analysing one baseline and five mitigation scenarios: (a) control (no intervention), (b) cool materials (roof albedo 0.80, ground albedo 0.40), (c) super cool materials (roof albedo 0.95), (d) 30 % non-irrigated vegetation, (e) 60 percent non-irrigated vegetation, and (f) a combination of super cool materials with 60 % vegetation. …”
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Remodeling of articular cartilage and subchondral zone of the tibia in exo‑prosthetics of the limb by Tatyana A. Stupina, Andrey A. Emanov, Viktor P. Kuznetsov, Evgenij N. Ovchinnikov

“…A tibial stump was modeled in the animals at the border of the middle and upper third of the diaphysis. …”

The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy by Lei Zhang, Lan Hu, Lan Hu, Lan Hu, Li Tan, Zhenjie Zhang, Mengying Chen, Wenbo Gan, Li Chen, Yan Zou, Shi Wang, Yu Pang, Zhenxin Fan, Junjie Liu

“…Multivariate biomarker models demonstrated excellent diagnostic performance, achieving area under the curve (AUC) of 0.919 (IgAN vs. control), 0.897 (MN vs. control) and 0.912 (IgAN vs. …”
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Fine Particle pH and Sensitivity to NH3 and HNO3 over South Korea During KORUS-AQ by Ifayoyinsola Ibikunle, Andreas Beyersdorf, Pedro Campuzano-Jost, Chelsea Corr, John D. Crounse, Jack Dibb, Glenn Diskin, Greg Huey, Jose-Luis Jimenez, Michelle J. Kim, Benjamin A. Nault, Eric Scheuer, Alex Teng, Paul O. Wennberg, Bruce Anderson, James Crawford, Rodney Weber, Athanasios Nenes

“…Because of this, HNO3 reductions achieved by NOX controls prove to be the most effective approach for all conditions examined, and that NH3 emissions can only partially affect PM reduction for the specific season and region. …”
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The role of artificial intelligence in promoting health and developing preventive strategies for diabetes by Ameneh Marzban

“…For instance, machine learning models can evaluate patient records, lifestyle factors, and genetic information to deliver precise risk assessments and personalized recommendations. …”
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Mathematical and statistical approaches in epidemiological investigation of hospital infection: A case study of the 2015 Middle East Respiratory Syndrome outbreak in Korea. by Youngsuk Ko, Eunok Jung

“…We developed a stochastic model based on individual case data to derive a likelihood function for disease transmission. …”
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Ambient fine particulate matter induces cardiac fibrosis through triggering ferroptosis by heme degradation induced-iron overload by Jinjin Jiang, Yang Li, Yuping Chen, Qin Wu, Shibin Ding

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Therapeutic effects of Jing Si herbal tea for chronic obstructive pulmonary disease: a comprehensive investigation from clinical to basic research by Chou-Chin Lan, Chou-Chin Lan, Po-Chun Hsieh, Kuo-Liang Huang, Kuo-Liang Huang, Mei-Chen Yang, Mei-Chen Yang, Guan-Ting Liu, Chan-Yen Kuo, I.-Shiang Tzeng, Yao-Kuang Wu, Yao-Kuang Wu

“…Cellular studies on lipopolysaccharide (LPS)-stimulated A549 cells demonstrated that JSHT effectively reduced the release of DAMPs such as HMGB1, FPR1, and extracellular ATP, and decreased the expression of inflammatory markers including pMAPK, pJNK, NF-kB, and cCaspase 3, and pro-inflammatory cytokines like IL-1, IL-6, IL-8, and TNF-α post-LPS induction.ConclusionJSHT improved the HRQL in patients with COPD, both in stable and exacerbated states. Cellular models demonstrated a reduction in DAMPs and inflammation, suggesting the potential of JSHT as a therapeutic agent for COPD through modulation of inflammatory responses.…”
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Analysis of the relationship between environmental particulate matter exposure and congenital diseases, as well as the epidemiological trends and burden of impact on newborns by Mulati Julaiti, Dilixiati Wubuli, Tingting Cui, Nadire Nijiati, Pengfei Huang, Bowen Hu

“…This may be attributed to improvements in air quality and the implementation of pollution control measures. However, forecasting models indicated potential future risks, suggesting that the burden of disease in newborns due to particulate matter exposure remains a concern.Conclusion: The study provides evidence of a causal link between environmental particulate and congenital diseases in newborns, highlighting the importance of air pollution reduction for the health of newborns. …”
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Urban-rural differences in age-specific mortality rates for breast cancer in China from 2009 to 2021 by Menglong Li, Jinlei Qi, Yaqi Ma, Wen Shu, Huidi Xiao, Lijun Wang, Peng Yin, Haoyan Guo, Sten H. Vermund, Maigeng Zhou, Yifei Hu

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The Effectiveness of Trauma-Aware Parenting Intervention on Relationship between Attachment and Emotional Disturbance in Adoptive Families by Mehrana Mehrana, Mansoureh Bahramipour Isfahani

“…Through these factors, the child gradually internalizes models of himself and others, which are called internal active models in the attachment perspective (Mohan, 2023). …”
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ISLAND Campus: a fee-free formal university educational intervention in mid- to later-life to reduce modifiable risk factors for dementia and improve cognition by Eddy Roccati, Alex Kitsos, Aidan David Bindoff, Jane Elizabeth Alty, Jane Elizabeth Alty, Larissa Bartlett, Jessica Marie Collins, Anna Elizabeth King, Hannah Fair, Kathleen Doherty, James Clement Vickers

“…IntroductionPrevious research has tended to focus on early-life education for dementia risk reduction, yet there are great gains for building cognitive reserve in mid- to later-life through educational interventions. …”
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White matter and cortical gray matter microstructural alterations in migraine: a NODDI and DTI analysis by Zhilei Li, Yanliang Mei, Lei Wang, Tianhua Fan, Cheng Peng, Kaibo Zhang, Shouyi Wu, Tong Chen, Zhenchang Zhang, Binbin Sui, Yonggang Wang, Xueying Yu

“…Methods Microstructural alterations in both white matter (WM) and cortical gray matter (GM) were evaluated among 40 chronic migraine (CM) patients, 35 episodic migraine (EM) patients, and 45 healthy controls (HCs) using Diffusion Tensor Imaging (DTI) and Neurite Orientation Dispersion and Density Imaging (NODDI) models. …”
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Avoidance of healthcare service use and correlates among HIV-positive patients in Vietnam: a cross-sectional study by Huong Lan Thi Nguyen, Thu Minh Bui, Carl A Latkin, Cyrus SH Ho, Roger CM Ho, Don Bradley, Toan Van Ngo, Vu Anh Trong Dam, Tham Thi Nguyen, Hien Thu Nguyen, Ga Mei Zeng, Quang N Nguyen

“…Objective The prevention of HIV/AIDS is not making sufficient progress. The slow reduction of HIV/AIDS infections needs to prioritise hesitancy towards service utilisation, including treatment duration, social support and social stigma. …”
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Clinical outcomes and outcome predictors of two-year assertive community treatment in Norway: an explorative prospective pre–post study by Torleif Ruud, Maria Lie Selle, Hanne K. Clausen, Kristin S. Heiervang, Sigrun Odden, Hanne Kilen Stuen, Anne Landheim

“…We measured fidelity to the ACT model using the Tool for Measurement of Assertive Community Treatment. …”
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A simplified hydroxyurea dosing approach for paediatric sickle cell anaemia in nigeria: addressing emergency care burden and adherence barriers in low-resource settings by Chisom Nri-Ezedi, Nwanneka Ugwu, Arinze Ulasi, Thomas Obiajulu Ulasi

“…Validation through larger or comparative studies is encouraged, and we recommend that healthcare policy-makers consider piloting and supporting similar models as part of national sickle cell control efforts.…”
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Cigarette smoke modulates methylation levels of LEF1-AS1 and impedes its expression: An experimental study by Bader O. Almutairi, Ahmed Rady, Bashayer S. Aljuhani, Mikhlid H. Almutairi

“…Long non-coding RNAs play a significant role in controlling several pathways in the cell, including lymphoid enhancer-binding factor 1 antisense RNA 1 (LEF1-AS1), which is found overexpressed in lung, oral, glioblastoma, and colon cancers and downregulated in leukemias. …”
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