Early neural dysfunction reflected in degraded auditory cortex responses in pre-regression heterozygous Mecp2 rats by Yuko Tamaoki, Samantha L. Kroon, Brendan M. Williams, Jonathan R. Riley, Crystal T. Engineer

“…This study documents primary auditory cortex responses to sounds in pre-regression heterozygous Mecp2 rats compared to age-matched wild-type controls. Pre-regression Mecp2 rats exhibited weaker and delayed cortical responses to speech sounds, alterations in the temporal processing of rapidly presented sounds, and an overrepresentation of high-frequency tones in conjunction with a reduction in the cortical representation of low-frequency tones. …”
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Hematological Response to Particle Debris Generated During Wear–Corrosion Processes of CoCr Surfaces Modified with Graphene Oxide and Hyaluronic Acid for Joint Prostheses by María L. Escudero, Maria C. García-Alonso, Belén Chico, Rosa M. Lozano, Luna Sánchez-López, Manuel Flores-Sáenz, Soledad Cristóbal-Aguado, Rafael Moreno-Gómez-Toledano, Soledad Aguado-Henche

“…This paper analyzes the biological alterations caused by wear–corrosion phenomena that occur in joints, both from the perspective of the worn surface (in vitro model) and the particles generated during the wear processes (in vivo model). …”
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Ecological drivers of malaria vector habitat and transmission over 1 year of long-lasting insecticidal net intervention in Côte d’Ivoire by Benoit Talbot, Ludovic P. Ahoua Alou, Alphonsine A. Koffi, Colette Sih, Edouard Dangbenon, Marius G. Zoh, Soromane Camara, Serge B. Assi, Raphael N’Guessan, Louisa A. Messenger, Natacha Protopopoff, Jackie Cook, Manisha A. Kulkarni

“…In this study, we aimed to test the effect of different LLIN products and other environmental factors on the ecological niche of three mosquito vector species using state-of-the-art ecological niche modelling approaches. Methods This study used data from a cluster randomized control trial that took place in Tiébissou, in Central Côte d’Ivoire. …”
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Characteristics and precipitation behavior of (Ti,V)(CxN1-x)-CrC3-MoS2 complex inclusions in GCr15 steel for cylindrical rollers of shield machine main bearings by Jinlong Wang, Wenrui Yang, Xiaohao Mei, Desheng Li, Hao Tian, Aiping Xiao, Zhengliang Xue

“…These inclusions exhibited a cubic structure and appeared dark red under optical microscopy. Under controlled laboratory conditions, an increase in the solidification cooling rate resulted in a marked rise in the number density of these complex inclusions, accompanied by a significant reduction in their average size. …”
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Structural performance of lightweight fibre-reinforced oil palm shell concrete subjected to impact loadings under varying boundary conditions by Idris Ahmed Ja'e, Zakaria Che Muda, Agusril Syamsir, Chiemela Victor Amaechi, Hamad Almujibah, Ali.E.A. Elshekh, Maaz Osman Bashir, Abdulrazak H. Almaliki

“…Regression models were developed to predict responses for specimens with up to 8 boundary conditions and 5 % PPF. …”
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Rumen fermentation profile and methane mitigation potential of mango and avocado byproducts as feed ingredients and supplements by Hassan Jalal, Ekin Sucu, Damiano Cavallini, Melania Giammarco, Muhammad Zeeshan Akram, Büşra Karkar, Min Gao, Luigi Pompei, Jorge Eduardo, Paraskevi Prasinou, Isa Fusaro

“…Data were analyzed using linear mixed models with Bonferroni-adjusted pairwise comparisons (p < 0.05). …”
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The effectiveness of a self-efficacy enhancement program on health behaviors and clinical outcomes in people with metabolic syndrome: A quasi-experimental study in Thailand by Chalermkwan Madsong, Jiraporn Lininger, Sangthong Terathongkum

“…Participants were divided into two groups: an experimental group (n = 35) and a control group (n = 35). The experimental group received the SEE program based on Self-Efficacy Theory, while the control group received only routine nursing care for 12 weeks. …”
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Malaria burden and associated risk factors among malaria suspected patients attending health facilities in Kaffa zone, Southwest Ethiopia by Aster Alemu, Beshada Lemma, Temesgen Bekele, Geleta Geshere, Eba Alemayehu Simma, Chernet Tuge Deressa, Tsige Ketema

“…Conclusion Even though Ethiopia was able to achieve a remarkable malaria burden reduction in the past few years, the recent interrupted malaria control activities, seasonal variability, and patient and health facility-associated factors have contributed to the current high malaria positivity rate documented in Kaffa zone, Southwest Ethiopia. …”
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PCSK9 targeting therapies for familial hypercholesterolaemia: a meta-analysis of efficacy on lipid biomarkers and safety in adults and children across 23 RCTs by Vinh Q T Ho, Nghi Bao Tran, Nhan Nguyen, Giang Son Arrighini, David Downes, Mrunalini Dandamudi, Victoria Zecchin Ferrara, Tri Huynh Quang Ho, Hemank Walia, Alejandro Barbagelata, Thorsten M Leucker, Juliana Giorgi

“…The safety profile of these therapies was favourable, with adverse event rates comparable to those of the controls.Conclusions PCSK9i and Inclisiran demonstrate significant and sustained reductions in LDL-C, ApoB, Lp(a) and TGL in FH patients, especially in heterozygous FH patients. …”
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Effects of population aging on quality of life and disease burden: a population-based study by Jun-Yan Xi, Bo-Heng Liang, Wang-Jian Zhang, Bo Yan, Hang Dong, Yuan-Yuan Chen, Xiao Lin, Jing Gu, Yuan-Tao Hao

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Role of permafrost thaw transitions in biogeochemical nitrogen cycling by Merritt N. Logan, Monique S. Patzner, Jacob P. VanderRoest, Bridget B. McGivern, Nivetha Srikanthan, Myrna J. Simpson, Amy M. McKenna, Kelly C. Wrighton, Casey Bryce, Andreas Kappler, Thomas Borch

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Transgenerational hepatotoxicity induced by bisphenol B as a substitute for bisphenol A by Huifeng Yue, Yangcheng Hu, Xiaoyun Wu, Yuchai Tian, Xiaomin Liang, Jiyue Zhang, Bin Li, Huizhen Zhu, Xiaotong Ji

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Hantaan virus infection induces human mucosal-associated invariant T cell pyroptosis through IRE1α pathway by Yusi Zhang, He Liu, Dalu Liu, Huiyuan Zhang, Ying Ma, Na Li, Chunmei Zhang, Manling Xue, Fenglan Wang, Xiaozhou Jia, Hui Zhang, Kang Tang, Xiaoyue Xu, Shijia Wang, Yiwen Wei, Xiaojing Yang, Jiajia Zuo, Lihua Chen, Boquan Jin, Yun Zhang

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Endangered Lymphocytes: The Effects of Alloxan and Streptozotocin on Immune Cells in Type 1 Induced Diabetes by Luiz A. D. Queiroz, Josiane B. Assis, João P. T. Guimarães, Emanuella S. A. Sousa, Anália C. Milhomem, Karen K. S. Sunahara, Anderson Sá-Nunes, Joilson O. Martins

“…Both ALX and STZ induced a decrease in the total number of circulating leukocytes and lymphocytes, with an increase in granulocytes when compared to control mice (CT). STZ-treated mice also exhibited an increase in neutrophils and a reduction in the lymphocyte percentage in the bone marrow. …”
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Cytoreductive surgery with multimodal therapies in advanced or metastatic ovarian, colorectal, and gastric cancers: a systematic review and meta-analysis of randomized trials by Xiaojun Yuan, Huazheng Liang, Xinxin Fu, Shirui Yang, Chenyu Xiang, Zisheng Chen

“…Hazard ratios (HRs) and 95% confidence intervals (CIs) were pooled using fixed- or random-effects models, depending on heterogeneity (I²). Findings From 16,064 records, 13 studies (n = 3,925 patients, control group = 1,894, experimental group = 2,031) met inclusion criteria. …”
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Neuroprotective properties of GABA and its derivatives in diabetic encephalopathy in old animals by I. N. Tyurenkov, D. A. Bakulin, A. V. Smirnov, M. R. Ekova, A. I. Bisinbekova, G. L. Snigur, Yu. I. Velikorodnaya, E. I. Morkovin, D. V. Verkholyak, O. S. Vasilyeva

“…Diabetes mellitus was modeled in white outbred male rats (12 months old) by the administration of a streptozotocin (65 mg/kg) and nicotinamide (230 mg/kg) combination. …”
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Iron deficiency in patients with cardiogenic shock: protocol for a scoping review by Sascha Ott, Alexander Meyer, Lorenzo Germinario, Yassine Ghamri, Benjamin O’Brien, Daniel Catena, Tobias Roeschl, Felix Schoenrath

“…To gain a deeper insight into the underlying pathophysiological mechanisms, the review will include basic research conducted on both human subjects and on animal models as well as observational, randomised controlled studies and systematic reviews and meta-analysis. …”
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RhoA/ROCK2 signaling pathway regulates Mn-induced alterations in tight junction proteins leading to cognitive dysfunction in mice by Yan Ma, Honggang Chen, Yuxin Jiang, Diya Wang, Michael Aschner, Wenjing Luo, Peng Su

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Research advances in the molecular regulatory mechanisms of fruit coloration in fruit trees by MA Shurui, CHI Fumei, SONG Yang

“…Based on the existing molecular mechanisms, the accumulation of fruit pigments can be directly regulated, and a coordinated interaction model of light quality, temperature and hormones can be established in facility cultivation to maximize the accumulation of fruit pigments. …”
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Potential activity of Ferula macrecolea essential oil for treating Giardia lamblia infection through modulating electrolytes and suppressing NF-κB p65 pathway by Iraj Salimikia, Seyed Ehsan Yaghoubi, Amal Khudair Khalaf, Leila Masoori, Javad Ghasemian Yadegari, Hossein Mahmoudvand, Hossein Mahmoudvand

“…Furthermore, the extract was shown to manage giardiasis in murine models by modulating electrolyte levels and inflammatory responses via suppressing the NF-κB p65/TLR pathways. …”
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