Strategies for introducing Wolbachia to reduce transmission of mosquito-borne diseases. by Penelope A Hancock, Steven P Sinkins, H Charles J Godfray

“…To explore this, we use a sex-structured model of Wolbachia-mosquito interactions. We first show that Wolbachia spread can be initiated with very few infected females provided the infection frequency in males exceeds a threshold. …”
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Knockdown of <i>POLG</i> Mimics the Neuronal Pathology of Polymerase-γ Spectrum Disorders in Human Neurons by Çağla Çakmak Durmaz, Felix Langerscheidt, Imra Mantey, Xinyu Xia, Hans Zempel

“…Notably, while chemical induction of mtDNA depletion via ddC could be rescued by the mitochondrial biosynthesis stimulators AICAR, cilostazol and resveratrol (but not MitoQ and formoterol) in control cells, <i>POLG</i>-knockdown cells were resistant to mitochondrial biosynthesis-mediated induction of mtDNA increase, highlighting the specificity of the model, and pathomechanistically hinting towards inefficiency of mitochondrial stimulation without sufficient Pol-γ activity. …”
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FiSC: A Novel Approach for Fitzpatrick Scale-Based Skin Analyzer&#x2019;s Image Classification by Guillermo Crocker Garcia, Muhammad Numan Khan, Aftab Alam, Josue Obregon, Tamer Abuhmed, Eui-Nam Huh

“…Our method involves modeling image features as a nine-dimensional feature vector, followed by a dimensionality reduction process to identify the most influential features and dominant areas within the feature space, enabling deployment on low-power devices. …”
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Antimicrobial and antioxidant activities and preclinical evaluation of common yarrow, Achillea millefolium L. by Gulmira Yeltay, Gulshat Anarbekova, Saule Mukhtubayeva, Kuandyk Myssaev, Kairat Iskakov, Nazym Bekenova, Zura Yessimsiitova, Moldir Tileshova

“…Preclinical evaluation involves in vivo studies on rodent models to assess the anti-inflammatory and wound-healing properties of yarrow extracts, demonstrating a 40% reduction in inflammation and a 35% acceleration in wound closure compared to control groups. …”
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A multiantigenic antibacterial nanovaccine utilizing hybrid membrane vesicles for combating Pseudomonas aeruginosa infections by Xinran Peng, Yuanjing Luo, Li Yang, Yi Yan Yang, Peiyan Yuan, Xinhai Chen, Guo‐Bao Tian, Xin Ding

“…The nanovaccine AuNP@HMV@SPs induces robust humoral and cellular immune responses, leading to destruction of bacterial cells and neutralization of their secreted toxins. In murine models of septicemia and pneumonia caused by P. aeruginosa, AuNP@HMV@SPs exhibits superior prophylactic efficacy compared to control groups including OMVs, or MMVs@SPs and HMV@SPs, achieving 100% survival in septicemia and > 99.9% reduction in lung bacterial load in pneumonia. …”
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Qualitative Phytochemical Analysis and Assessments of Analgesic and Antidiarrheal Activity of the Methanolic Leaf Extract of Cheilanthes tenuifolia: In Vivo Study by Asraful Islam Rakib, Raihan Chowdhury, Md. Shimul Bhuia, Md. Sakib Al Hasan, Salehin Sheikh, Siddique Akber Ansari, Irfan Aamer Ansari, Muhammad Torequl Islam

“…The vehicle performed as a negative control (NC), while diclofenac sodium (DCN) (25 mg/kg), loperamide (LOP) (3 mg/kg), bismuth subsalicylate (BSS) (10 mg/kg), and nifedipine (NDP) (2.5 mg/kg) were supplied as positive controls (PC) (p.o.). …”
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RETRACTED ARTICLE: Reducing PKCδ inhibits tumor growth through growth hormone by inhibiting PKA/CREB/ERK signaling pathway in pituitary adenoma by Xi Chen, Jianyao Mao, Liwei Zhou, Weichao Jiang, Zhangyu Li, Yukui Li, Sifang Chen, Guowei Tan, Yuanyuan Xie, Chen Wang, Jinli Sun

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Exploring the Impact of Urinary Metal Exposure on Blood Lipid Profiles in Chinese Adults: Mediating Roles of Health‐Related Indicators by Jianqin Zhong, Zixuan Xu, Tingting Yang, Leilei Liu, Renhua Zhang, Yuan Wang, Linfei Huang, Feng Hong

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MRI evidence of gray matter loss in COVID‐19 patients with cognitive and olfactory disorders by Serena Capelli, Alberto Arrigoni, Angela Napolitano, Giulio Pezzetti, Andrea Remuzzi, Rosalia Zangari, Ferdinando Luca Lorini, Maria Sessa, Anna Caroli, Simonetta Gerevini

“…Results The multi‐morphometric analysis revealed statistically significant (p < 0.05 corrected for multiple comparisons) reduction in GM regional volumes, in voxel‐wise GM density and in cortical thickness in both COVID‐CD and COVID‐OD patient groups as compared to controls. …”
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Anthropometric changes and risk of diabetes: are there sex differences? A longitudinal study of Alberta’s Tomorrow Project by Ming Ye, Paula J Robson, Dean T Eurich, Jennifer E Vena, Jian-Yi Xu, Jeffrey A Johnson

“…For population-based public health programmes aiming to control obesity and incidence of diabetes, it may not be necessary to set up sex-specific goals for anthropometric reduction.…”
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Biochemical blood counts in the application of fish oil preparations in conditions of intense physical activity by E. A. Knyazeva, A. V. Deryugina, P. V. Yastrebov, G. А. Boyarinov

“…The objective was to evaluate the effect of fish oil and ozonated fish oil in the dynamics of biochemical parameters of blood plasma while modeling physical activity up to “to failure” in rats.Methods and materials. …”
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The association between disease activity and health utility value in Chinese patients with rheumatoid arthritis: A cross-sectional study based on the CREDIT cohort by YU Bing, LI Lu, LI Mengtao, WANG Yanhong

“…Conclusions Health utility values of RA patients are closely related to disease activity, with higher disease activity leading to a significant reduction in health utility values. Early control of RA disease activity may help improve patients' quality of life.…”
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Protein disulfide isomerase is essential for osteoblast differentiation in mice by Yue Lu, Aizhen Yang, Zhenzhen Zhao, Yue Han, Depei Wu, Yi Wu

“…Abstract Protein disulfide isomerase (PDI) is an oxidoreductase responsible for the formation, reduction and isomerization of disulfide bonds of nascent proteins in endoplasmic reticulum (ER). …”
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Effect of Motivational Enhancement Therapy on Patterns of Substance Abuse in Postpartum Women: A Randomized Clinical Trial by Fatemeh Esmaeilinejad Hasaroeih, Nasim Shahrahmani, Atefeh Ahmadi, Moghaddameh Mirzaee, Katayoun Alidousti, Morteza Hashemian

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Optimizing CaO-based CO2 adsorption: Impact of operating parameters by Chengzhuang Zhang, Jia Fang, Zhiqiang Han, Peng Chen, Xilong Xu, Kejian Wang, Yunxi Shi, Jianxiong Liao

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Thermal performance estimation and optimisation of a shallow geothermal compound heat pumping system for combined process heating and cooling by J.E. De León-Ruiz, R. Beltrán-Chacón, I. Carvajal-Mariscal, M. Venegas, A. Ponsich

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Cre recombinase affects calcium dynamics already in young mice by János Levin Liffers, Jan Peter Reinhardt, Matthias Dodo Seidl, Uwe Kirchhefer, Frank Ulrich Müller, Jan Sebastian Schulte

“…Therefore, it is essential to use Cre-positive mice as controls when analyzing knockout models generated by the Cre/LoxP system.…”
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Leaky Dams as Nature-Based Solutions in Flood Management Part II: Mechanisms, Effectiveness, Environmental Impacts, Technical Challenges, and Emerging Trends by Umanda Hansamali, Randika K. Makumbura, Upaka Rathnayake, Hazi Md. Azamathulla, Nitin Muttil

“…Leaky dams have become essential nature-based solutions for flood management, providing sustainable alternatives to traditional engineered flood control methods. This review delves into the mechanisms by which leaky dams operate, including the regulation of water flow through velocity reduction and distribution across floodplains, effective sediment trapping and soil quality enhancement, and the facilitation of groundwater recharge and water table stabilization. …”
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Transcriptome profiling of L. infantum-infected human macrophages reveals sex-specific type I interferon induction. by Annika Bea, Helena Fehling, Fabian Hausmann, Fahten Margot Habib, Melanie Lütkemeyer, Lara Buer, Carola Schäfer, Charlotte Sophie Hansen, Barbara Honecker, Stefan Bonn, Bianca Elisabeth Schneider, Joachim Clos, Hanna Lotter

“…Field studies of human infections and controlled experimental rodent models have shown that certain clinical forms of leishmaniasis occur more frequently in males. …”
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Assessing the Potential of a Hybrid Renewable Energy System: MSW Gasification and a PV Park in Lobito, Angola by Salomão Joaquim, Nuno Amaro, Nuno Lapa

“…A fixed-bed downdraft gasifier was selected for MSW gasification, where the thermal decomposition of waste under controlled air flow produces syngas rich in CO and H₂. …”
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