EVALUATION OF THE PHLORIDZINE AND ICARIIN INFLUENCE RATE ON THE LAVEL OF WORKINC CAPACITY AND NEUROLOGICAL STATUS OF THE ANIMALS IN THE CONDITIONS OF EXHAUSTING PHYSICAL AND PSYCOE... by A. V. Voronkov, I. N. Dyakova, D. I. Pozdnyakov, N. A. Muravyova

“…The administration of icariin led to the working capacity reduction of mice by 44.6%  against the original indices of this group and by 55% in comparison with control animals, decrease of motion and orient-exploratory activity in the tests of “open field” and “elevated plus maze”.…”
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New insights into the microvascular mechanisms of drag reducing polymers: effect on the cell-free layer. by Judith Brands, Dustin Kliner, Herbert H Lipowsky, Marina V Kameneva, Flordeliza S Villanueva, John J Pacella

“…Drag-reducing polymers (DRPs) significantly increase blood flow, tissue perfusion, and tissue oxygenation in various animal models. In rectangular channel microfluidic systems, DRPs were found to significantly reduce the near-wall cell-free layer (CFL) as well as modify traffic of red blood cells (RBC) into microchannel branches. …”
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The impact of vegetative and solid roadway barriers on particulate matter concentration in urban settings. by Roby Greenwald, Jeremy A Sarnat, Christina H Fuller

“…We used Generalized Linear Mixed Models (GLMMs) to estimate the effect of barrier type on the ratio of particle concentrations at the comparison site relative to the roadside site while controlling for covariates including wind direction, temperature, relative humidity, traffic volume, and distance to the roadway. …”
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Protective effect of purple sweet potatoes (Ipomoea batatas L.) against rat breast cancer by Carmen R. Silva-Correa, Julio Hilario‑Vargas, Abhel A. Calderón-Peña, Víctor E. Villarreal-La Torre, Cinthya L. Aspajo-Villalaz, Natalia Bailon-Moscoso, Juan Carlos Romero-Benavides, Oscar Herrera-Calderon, William A. Sagástegui-Guarniz, Julio A. Castañeda-Carranza, Walter E. Janampa-Castillo, José L. Cruzado-Razco

“…Tumor latency was significantly prolonged in the 600 mg/kg group (101 days) compared to the DMBA control (88 days). In addition, this group showed a marked reduction in tumor volume (2.26 cm3 vs. 15.21 cm3; p < 0.05). …”
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White Matter Magnetic Resonance Diffusion Measures in Multiple Sclerosis with Overactive Bladder by Xixi Yang, Martina D. Liechti, Baris Kanber, Carole H. Sudre, Gloria Castellazzi, Jiaying Zhang, Marios C. Yiannakas, Gwen Gonzales, Ferran Prados, Ahmed T. Toosy, Claudia A. M. Gandini Wheeler-Kingshott, Jalesh N. Panicker

“…Conclusions: This study identified that lesions affecting different WM tracts in MS can result in OAB symptoms and demonstrated the role of the WM in the neural control of LUT functions. By using DTI, the association between OAB symptom severity and WM changes were identified, adding knowledge to the current LUT working model. …”
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Supporting self-management with an internet intervention for low back pain in primary care: a RCT (SupportBack 2) by Adam W A Geraghty, Taeko Becque, Lisa C Roberts, Jonathan Hill, Nadine E Foster, Lucy Yardley, Beth Stuart, David A Turner, Gareth Griffiths, Frances Webley, Lorraine Durcan, Alannah Morgan, Stephanie Hughes, Sarah Bathers, Stephanie Butler-Walley, Simon Wathall, Gemma Mansell, Malcolm White, Firoza Davies, Paul Little

“…Overall, there were no significant differences between the interventions and usual care with regard to pain intensity (measured as current pain, least pain in the last 2 weeks and average pain over the last 2 weeks) in a repeated-measures model, over 12 months. Participants in both intervention arms reported a significant reduction of around a day less in pain per month, over 12 months, compared to usual care. …”
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Response mitigations of adjacent structure with MPTMD under real and stochastic excitations by Mohammad Alibabaei Shahraki

“…After modeling the structures, the MPTMD system is applied at different stages to control the dynamic responses, mitigate the impact between the structures, and reduce the Park-Ang damage index. …”
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Single nuclei RNA-sequencing unveils alveolar macrophages as drivers of endothelial damage in obese HFpEF-related pulmonary hypertension by Era Gorica, Jacopo Spezzini, Iliana Papadopoulou, Marialucia Telesca, Valeria Masciovecchio, Shafeeq A. Moahmmed, Alessandro Mengozzi, Hung-Wei Cheng, Natalia Atzemian, Ludovica Di Venanzio, Alessia Mongelli, Omer Dzemali, Vincenzo Calderone, Francesco Paneni, Christian M. Matter, Burkhard Ludewig, Frank Ruschitzka, Sarah Costantino

“…SnRNA-seq of mouse lungs revealed transcriptional alterations in AMs, with a significant reduction in their abundance in PH-cHFpEF mice. These changes were associated with dysregulation of transcriptional programs involved in pyroptosis, defective autophagy and inflammation in AMs from PH-cHFpEF vs. control mice, as shown by the upregulation of c-Fos, Dusp1, Pim-1 and Ccn1. …”
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Routing Protocols and Mobility Predictions for UAV Data Collection From Agricultural Sites: A Survey by Khemis Ben Samuel, Stephen D. Wolthusen, Julianne Sansa Otim, Roseline Nyongarwizi Akol, Mary Nsabagwa

“…This work reviewed routing protocols such as reactive and hybrid as well as mobility predictions such as regressive and Markov models with the central argument of topology control and path optimizations. …”
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Performance analysis and parameter optimization of microchannel heat sink with porous-solid composite ribs by Chunjie Liu, Shixin Xing, Wenrui Wang, Dinghua Hu

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Effectiveness of health promotion utilizing word puzzle games in enhancing older adults' knowledge and attitudes regarding hypertension management by Mia Fatma Ekasari, Aan Nurhasanah, Eros Siti Suryati, Puspita Hanggit Lestari, Siti Badriah, Ahmad Jubaedi

“…However, the result has not shown an optimal reduction in the number of hypertension sufferers. …”
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Comparative Study between Artificial Sweeteners Such as Aspartame and Neotame on Neurobehavioral and Some Haematological Parameters in Male Rats by Ahmed J. Mohammed, Hassan K. Al-Awadi, Hamzah H. K. Al-Shukri

“…The open field test results demonstrated a marked reduction in locomotor activity in both treatment groups compared to controls (p < 0.05). …”
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Does Traumatic Brain Injury Lead to Criminality? A Whole-Population Retrospective Cohort Study Using Linked Data. by Peter W Schofield, Eva Malacova, David B Preen, Catherine D'Este, Robyn Tate, Joanne Reekie, Handan Wand, Tony Butler

“…<h4>Results</h4>In multivariable models, relative to general population controls, TBI was associated with any conviction (males: Hazard Ratio (HR) = 1.58 (95% CI 1.46 to 1.72); females: HR = 1.52 (95% CI 1.28 to 1.81)); and similar Hazard Ratios were obtained for the sibling analyses in males (HR = 1.68 (95% CI 1.31-2.18)) and females (HR 1.27 (95% CI 0.71-2.29)). …”
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A literature review of economic evaluations for a neglected tropical disease: human African trypanosomiasis ("sleeping sickness"). by C Simone Sutherland, Joshua Yukich, Ron Goeree, Fabrizio Tediosi

“…Results from the existing studies focused on the cost-effectiveness of interventions for the control and reduction of disease transmission. Modelling was a common method to forecast long-term results, and publications focused on interventions by category, such as case detection, diagnostics, drug treatments, and vector control. …”
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IoT-Enabled Adaptive Traffic Management: A Multiagent Framework for Urban Mobility Optimisation by Ibrahim Mutambik

“…Unlike conventional models that rely on static or reactive approaches, this framework integrates real-time data from IoT-enabled sensors with predictive analytics to enable proactive adjustments to traffic flows. …”
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Enhancing breast Cancer immunotherapy using gold nanoparticles carrying tumor antigens by Mahtab Moshref Javadi, Neda Soleimani, Ashkan Zandi

“…The immunogenicity studies revealed high levels of cytokine secretion for IFN-γ, IL- 1, IL- 18, and TCD8+, along with reduced levels of IL- 4 cytokine in immunized mouse models in various treatment groups. In the prophylactic group, tumor growth was delayed, while in the therapeutic group, mouse models had more than 85% reduction within 31 days compared to the control group. …”
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Dual-functional injectable adhesive hydrogel delivering ginger-derived doxorubicin vesicles for osteosarcoma recurrence suppression and post-resection wound healing by Qiang Zhang, Qiang Zhang, Qiang Zhang, Qiang Zhang, Yu Zhang, Yu Zhang, Yu Zhang, Yu Zhang, Hui Chen, Hui Chen, Hui Chen, Hui Chen, Lei-Na Sun, Lei-Na Sun, Lei-Na Sun, Lei-Na Sun, Bin Zhang, Bin Zhang, Bin Zhang, Bin Zhang, Dong-Sheng Yue, Dong-Sheng Yue, Dong-Sheng Yue, Dong-Sheng Yue, Chang-Li Wang, Chang-Li Wang, Chang-Li Wang, Chang-Li Wang, Zhen-Fa Zhang, Zhen-Fa Zhang, Zhen-Fa Zhang, Zhen-Fa Zhang

“…The system facilitates hemostasis through physical barrier formation and activation of coagulation factors, while GVs and DOX provide controlled release for ROS scavenging, reduction of inflammation, and targeted tumor cell elimination.ResultsIn vitro experiments demonstrated the hydrogel’s ability to efficiently remove ROS and promote osteogenic differentiation. …”
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Microfluidics as a promising technology for personalized medicine by Zahra Oushyani Roudsari, Zahra Esmaeili, Nafiseh Nasirzadeh, Saeed Heidari Keshel, Farshid Sefat, Hassan Bakhtyari, Samad Nadri

“…These conditions have enabled the potential to carry out studies like; disease modeling, drug screening, and improving the accuracy of diagnostic methods. …”
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An Evaluation Of Corporate Sustainability In Context Of The Jevons Paradox by Marcel Biewendt, Florian Blaschke, Arno Böhnert

“…The first part of this paper summarizes various definitions, organizational theories, and measures used for CS and its derivatives like green controlling, IT, and manufacturing. Second, a case study is given that combines the aforementioned sustainability models. …”
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Effects of dust deposition on solar reflectance of spacecraft radiators by Hiroki Gonome, Takamasa Hayashi, Takashi Unno, Sumitaka Tachikawa

“…Numerical simulations using Mie theory and radiative transfer models confirmed the experimental trends. Even moderate dust coverage caused up to 17 % reflectance loss, suggesting a substantial risk to thermal control. …”
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