Efficacy of therapeutic interventions for idiopathic recurrent pregnancy loss: a systematic review and network meta-analysis by Jorge Lima, Jorge Lima, João Guerreiro, Miguel Ângelo-Dias, Sofia Silvério Serra, Teresa Costa, Natália Marto, João Feldman de Pinho, João Costa, Rodrigo Ruano, Gonçalo Silva Duarte, Gonçalo Silva Duarte

“…References from key articles were also manually searched. Randomized controlled trials assessing the efficacy and safety of any prophylactic intervention that were conducted in adult women with RPL were included. …”
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Predictors of recurrence after conversion therapy in unresectable hepatocellular carcinoma treated with HAIC, bevacizumab, and sintilimab by Chang-Fu Liu, Xiao-Hui Zhao, Shi-Bo Zhu, Hai-Peng Yu, Wen-Ge Xing, Hui-Kai Li

“…The median RFS was 22.2 months (95% CI: 18.3–28.0); the 1- and 2-year RFS rates were 71.7% and 46.9%, respectively. The RCS model showed that an AFP decline greater than 25% and tumor size reduction significantly lowered the risk of 1-year recurrence, but reductions in tumor size beyond 60% did not confer additional benefits in reducing recurrence risk. …”
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Implementation and maintenance of breast cancer screening among Chinese rural women: a mixed-methods evaluation based on RE-AIM framework by Huijiao Yan, Qiankun Wang, Le Dang, Xianzhi Duan, Zhirong Bai, Yinhui Feng, Linlin Zhang, Suyala Qimuge, Haiying Gao, Xinchun Wang, Min Sun, Shuxia Ma, Cailing Yan, Fanghui Zhao, Youlin Qiao

“…A key challenge in program maintenance was the reduction in quality control, supervision, and training efforts. …”
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Epidemiologic evaluation of human papillomavirus type competition in unvaccinated women from Xiamen, China by Yu Chen, Yu Chen, Qing Li, Liya Du, Zhuowen Du, Yixi Zhou, Yanru Huang, Jian Zhang, Wenbo Wang, Lutan Zhang, Jieqiong Xie, Chao Xu, Yunsheng Ge, Xingmei Yao, Yulin Zhou, Yulin Zhou

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Impact of Chronic Intermittent Hypoxia on Cognitive Function and Hippocampal Neurons in Mice: A Study of Inflammatory and Oxidative Stress Pathways by Zhang K, Ma D, Wu Y, Xu Z

“…The severe CIH group had a longer escape latency compared to the mild CIH group (p < 0.001) and the control group (p < 0.01), while the mild CIH group took longer than the control group (p < 0.01). …”
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Selective metabolic regulations by p53 mutant variants in pancreatic cancer by Sabrina Caporali, Alessio Butera, Alessia Ruzza, Carlotta Zampieri, Marina Bantula’, Sandra Scharsich, Anna-Katerina Ückert, Ivana Celardo, Ian U. Kouzel, Luigi Leanza, Andreas Gruber, Joan Montero, Angelo D’Alessandro, Thomas Brunner, Marcel Leist, Ivano Amelio

“…Thus, the two variants selectively control different metabolic pathways in pancreatic cancer cells. …”
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Cornelian cherry, cardiometabolic health, and dietary intake: a GRADE-assessed systematic review and meta-analysis by Morteza Omrani, Mostafa Norouzzadeh, Hamid Ahmadirad, Mehrnaz Abbasi, Mitra Kazemi Jahromi, Farshad Teymoori, Minoo Hasan Rashedi, Seyedeh Tayebeh Rahideh, Hossein Farhadnejad, Parvin Mirmiran, Mohsen Khaleghian

“…The weighted mean difference(WMD) and 95% confidence interval(95%CI) for each outcome were determined using a random-effects model. The certainty of the assessments was further examined using the GRADE assessment. …”
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Tissue-Specific Expression Analysis and Functional Validation of <i>SiSCR</i> Genes in Foxtail Millet (<i>Setaria italica</i>) Under Hormone and Drought Stresses, and Heterologous... by Yingying Qin, Ruifu Wang, Shuwan Chen, Qian Gao, Yiru Zhao, Shuo Chang, Mao Li, Fangfang Ma, Xuemei Ren

“…Analysis of heterologous expression under the control of the 35S promoter revealed that <i>SiSCR</i> genes were expressed in root cortical/endodermal initial cells, endodermal cells, cortical cells, and leaf stomatal complexes. …”
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No Long-Term Superiority of Cord-Derived PRP over Autologous PRP in Knee Osteoarthritis: A Prospective Cohort Study by Michele Coviello, Antonella Abate, Giuseppe Maccagnano, Alessandro Geronimo, Elio Caiaffa, Vittorio Nappi, Vincenzo Caiaffa, Giuseppe Solarino

“…Statistical analysis was performed using the Mann–Whitney U, Exact Fisher test, repeated measures general linear model (GLM) and multivariate logistic regression. …”
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Regulatory Effect of 1,25(OH)2D3 on TGF-β1 and miR-130b Expression in Streptozotocin-Induced Diabetic Nephropathy in Rats by Yuetong Liu, Ye Yang, Qin Wang, Apaer Kahaer, Jiyun Zhang, Jing Liao, Mairemugu Abudureyimu, Reyila Yahefu, Jing Qi, Lei Zhao, Jun Zhu

“…To investigate the role of microRNA-130b in 1,25(OH)2D3 mediated improvement of renal fibrosis via transforming growth factor-beta 1 in a rat model of diabetic nephropathy (DN). Methods. DN was induced in 30 rats by intraperitoneal injection of streptozotocin. …”
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Reduced IFN-γ-expressing SARS-CoV-2 specific CD4+ T cells and transient CD8 + T cell activation associate with higher HOMA-IR 1-year post COVID-19 in obese individuals by Rona Kartika, Dicky Levenus Tahapary, Farid Kurniawan, Syahidatul Wafa, Tika Pradnjaparamita, Simon P. Jochems, Heri Wibowo, Imam Subekti

“…Our previous study showed a 22% median increase in homeostasis model assessment-estimated insulin resistance (HOMA-IR) in obese individuals at 12 months post-infection compared to acute infection. …”
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Effects of Tanreqing injection against ventilator-associated pneumonia: a meta-analysis and systematic review of clinical studies by Pochen Li, Yang Wu, Danxia Ge, Ruyi Xu, Qianping Zhang, Yujiao Li, Lingyao Zhang, HsuanChieh Peng, Fangyu Yu

“…Furthermore, the TRQI demonstrated superior performance compared to the control group in CPIS (Clinical Pulmonary Infection Score) assessments (P &lt; 0.00001). …”
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How the HBRC contributes to the Sustainability in Egypt by Khaled El Zahaby

“…Moreover, HBRC is taking a substantial role in the quality control and construction supervision of the national projects.…”
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“Agent – Environment” Evolution Mechanism of Greenbelt from the Perspective of Complex Adaptive System: A Case Study of Beijing’s Greenbelts by Song LIU, Peiyu SHEN, Dizi LIU, Zhaocheng BAI

“…ObjectiveSince the first successful practice in London in the 1930s, greenbelt has become an important land control and land use planning idea. Greenbelts help solve problems related to urban sprawl and provide multiple ecological, social and economic functions that have profound impact on sustainable regional development. …”
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Microtubule destabilization is shared by genetic and idiopathic Parkinson's disease patient fibroblasts. by Daniele Cartelli, Stefano Goldwurm, Francesca Casagrande, Gianni Pezzoli, Graziella Cappelletti

“…Taken together, our results suggest that microtubule destabilization is a point of convergence of genetic and idiopathic forms of parkinsonism and highlight, for the first time, that microtubule dysfunction occurs in patients and not only in experimental models of Parkinson's disease. Therefore, these data contribute to the knowledge on molecular and cellular events underlying Parkinson's disease and, revealing that correction of microtubule defects restores control phenotype, may offer a new therapeutic target for the management of the disease.…”
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Application of Improved Whale Algorithm to Optimize Dephosphorization Process Parameters in Converter Steelmaking by Congrui Wu, Yueping Kong

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Multi-Agent System for Smart Roll-on/Roll-off Terminal Management: Orchestration and Communication Strategies for AI-Driven Optimization by Nicoletta González-Cancelas, Javier Vaca-Cabrero, Alberto Camarero-Orive

“…The study evaluates the system’s potential benefits compared to traditional port management models, highlighting improvements in transit time reduction, resource utilization, and operational resilience. …”
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Variations in Sources, Composition, and Exposure Risks of PM2.5 in both Pre-Heating and Heating Seasons by Dingyuan Yang, Zhiyong Li, Ziyuan Yue, Jixiang Liu, Zhen Zhai, Zelin Li, Minglei Gao, Ailian Hu, Wenjia Zhu, Ning Ding, Zhenxin Li, Songtao Guo, Xiangxue Wang, Lei Wang, Jihong Wei

“…In contrast, the non-CRs for children and adults decreased in the HS due to a reduction in Ba of 85.5% in the HS. A total of seven sources, including fugitive dust (FD), vehicle exhaust (VE), coal combustion (CC), secondary inorganic aerosol (SIA), industrial emissions (IE), glass production (GP), and biomass burning (BB), were identified using a PMF model. …”
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Design and Technological Aspects of Integrating Multi-Blade Machining and Surface Hardening on a Single Machine Base by Vadim Skeeba, Vladimir Ivancivsky, Aleksey Chernikov, Nikita Martyushev, Nikita Vakhrushev, Kristina Titova

“…The verification of the modeling results was carried out using in situ experiments employing the following: optical and scanning microscopy; and mechanical and X-ray methods of residual stress determination. …”
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Contributors to caregiver burden, depression, and anxiety in the partners of professional American-style football players: a cross-sectional study by Niki Konstantinides, Niki Konstantinides, Paula S. Atkeson, Heather DiGregorio, Inana Dairi, Cheyenne Brown, Kairi Noriega, Jillian Baker, Jillian Baker, Valencia Taylor, Christy Glass, Lewis E. Kazis, Lewis E. Kazis, Rachel Terrill, Frank E. Speizer, Frank E. Speizer, Frank E. Speizer, Ross D. Zafonte, Ross D. Zafonte, Ross D. Zafonte, Herman A. Taylor, Herman A. Taylor, Aaron L. Baggish, Aaron L. Baggish, Aaron L. Baggish, Marc G. Weisskopf, Marc G. Weisskopf, Alicia J. Whittington, Rachel Grashow, Rachel Grashow

“…Models that controlled for established risk factors identified significant associations between increased marital satisfaction and a 5.87 reduction in caregiver burden score (95% CI= −7.32, −4.43; p &lt; 0.001), 1.26 score reduction in depression score (95% CI = −1.75, −0.77; p &lt; 0.001) and 1.32 reduction in anxiety score (95% CI = −1.89, −0.75; p &lt; 0.001). …”
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