Cost-Effective Emission Abatement in Europe Considering Interrelations in Agriculture by Corjan Brink, Ekko van Ierland, Leen Hordijk, Carolien Kroeze

“…We used an optimisation model that is largely based on the RAINS model but that also includes emissions of N2O and CH4 from agriculture and technical measures to reduce these emissions. …”
Get full text

Low-frequency rTMS modulates small-world network properties in an AVH-related brain network in schizophrenia by Lin Zhang, Li Guo, Xiaohui Liu, Jing Han, Yuanqiang Zhu, Chaozong Ma, Ye Li, Weiliang Ye

“…Notably, responders showed greater connectivity changes, which were correlated with AVH severity reduction, highlighting the role of network modulation in treatment response.ConclusionThese findings support the network dysregulation model of AVH in schizophrenia and demonstrate that rTMS can modulate AVH-related connectivity, partially restoring network efficiency. …”
Get full text

Optimizing the lead time of operational flexibility trading from distributed industrial energy systems in future energy and flexibility markets by Daniel Bull, Adrian Bürger, Markus Bohlayer, Marco Braun, Anke Weidlich

“…In this study, we analyze this cost effect of varying lead times on flexibility provision by simulating a 48-hour moving horizon model predictive control for multiple distributed energy systems on a market platform, delivering flexibility under different lead time scenarios. …”
Get full text

Organizational Culture and Stock Price Crash Risk by Gholamreza Kordestani, Ramin Eskandari, Mahdi Shams

“…Data from 124 companies listed on the Tehran Stock Exchange over ten years from 2012 to 2021 were selected, and the hypotheses were tested using multiple linear regression and panel data models. Organizational culture was assessed through four quadrants (control-oriented, Creation-oriented, collaboration-oriented, and competition-oriented) utilizing a text analysis approach and software tools including Adobe Acrobat, Microsoft Edge, and OCR (using Python programming language). …”
Get full text

The impact of intensive management on pain intensity in patients with rheumatoid arthritis and psoriatic arthritis: secondary analysis of three clinical trials by Fowzia Ibrahim, David L. Scott, Ian C. Scott

“…In the two trials employing the most intensive management strategies (CARDERA; TITRATE) overall reductions in pain scores were significantly greater (6.6 to 6.8 units in adjusted linear regression models), and significantly more achieved ≥ 30% reductions in pain with intensive vs. control treatment (adjusted logistic regression models: CARDERA odds ratio [OR] 1.9, P = 0.009; TITRATE OR 2.2, P = 0.002). …”
Get full text

Efficacy and safety of anticoagulants in elderly atrial fibrillation patients: a systematic review and network meta-analysis by Xingran Zhao, Jun Luo, Xuanda Pan, Linlin Fang, Chengjiang Liu

“…Statistical analysis was performed using a Bayesian random-effects network meta-analysis model to calculate odds ratios (ORs) and 95% confidence intervals (CIs). …”
Get full text

Effects of replacing Laminaria japonica with mixed seaweed meal on growth performance, digestive and metabolic enzyme activities, and immune function of the sea cucumber Apostichop... by Bin Xia, Zhengyong Liu, Qingfei Li, Dongxue Xu, Ji Liu, Jinghua Chen

“…The integrated biomarker response model revealed that 25 % substitution level yielded the highest physiological adaptability, and substitution levels exceeding 50 % induced significant stress responses. …”
Get full text

The influence of Tetranychus cinnabarinus-induced plant defense responses on Aphis gossypii development by Guang-min MA, Xue-yan SHI, Zhi-jiao KANG, Xi-wu GAO

“…Carmine spider mites (Tetranychus cinnabarinus) and cotton aphids (Aphis gossypii) are both serious pests of cotton, and cause reductions in yields of this key agricultural crop. …”
Get full text

The impact of school water, sanitation, and hygiene improvements on infectious disease using serum antibody detection. by Anna N Chard, Victoria Trinies, Delynn M Moss, Howard H Chang, Seydou Doumbia, Patrick J Lammie, Matthew C Freeman

“…<h4>Methodology/principal findings</h4>We randomly selected 21 beneficiary primary schools and their 21 matched comparison schools participating in a matched-control trial of a comprehensive school-based WASH intervention in Mali. …”
Get full text

The Relationship Between Nutrition Knowledge and Dietary Behavior of Student-Athletes by Kerry Smith, Kathleen Fritch, James Rost, Amy Jo Riggs, Juliann McBrayer, Monika Krah

“…Correlation between nutrition knowledge and dietary behavior and hierarchical linear regression modeling were utilized in this study. No significant relationship was found between nutrition knowledge and dietary behavior while controlling for the identified covariates. …”
Get full text

Effects of women's groups practising participatory learning and action on preventive and care-seeking behaviours to reduce neonatal mortality: A meta-analysis of cluster-randomised... by Nadine Seward, Melissa Neuman, Tim Colbourn, David Osrin, Sonia Lewycka, Sonia Lewycka, Kishwar Azad, Anthony Costello, Sushmita Das, Edward Fottrell, Abdul Kuddus, Abdul Kuddus, Dharma Manandhar, Nirmala Nair, Bejoy Nambiar, Neena Shah More, Tambosi Phiri, Prasanta Tripathy, Audrey Prost

“…To determine whether behaviour change was related to group attendance, we used random effects models to assess associations between outcomes and the following categories of group attendance and allocation: women attending a group and allocated to the intervention arm; women not attending a group but allocated to the intervention arm; and women allocated to the control arm. …”
Get full text

The surface protein Gbp of Fusobacterium nucleatum inhibits osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 by Rui Dong, Meihui Li, Xiu Feng Gu, Haiting Gao, Ziyi Wei, Houbao Qi, Jun Zhang, Qiang Feng

“…An experimental periodontitis model in mice and primary osteoblast cultures were used to investigate the effects of Fn and Gbp on osteogenic differentiation. …”
Get full text

Post-traumatic stress disorder, trauma and parenting stress: an individual participant data meta-analysis by Laurien Meijer, Kathleen Thomaes, Matthijs Blankers, Maja Deković, Molly R. Franz, Rolf Kleber, Elise M. van de Putte, Elisa van Ee, Elena Camisasca, Steffany J. Fredman, Dominik Moser, Larry L. Mullins, Maria Muzik, Mathilde Overbeek, Abigail Palmer Molina, Jessica Riggs, Katherine Rosenblum, Kristin Samuelson, Daniel Schechter, Chiara Suttora, Catrin Finkenauer

“…The proportion of individual-level variance in parenting stress explained by the model with main and interaction effects while controlling for education level was small to medium (R2 = .12, p = .003).Conclusion: This study is the first to investigate relations among parental childhood interpersonal trauma, PTSD, and parenting stress across studies using IPDMA methodology. …”
Get full text

Explaining Observed Daily Variations and Decadal Trends in the Diurnal Air Temperature Range by Sarosh Alam Ghausi, Kaighin McColl, Erwin Zehe, Axel Kleidon

Get full text

Strain promoted azide alkyne cycloaddition, an efficient surface functionalization strategy for microRNA magnetic separation by Djamila Kechkeche, Sirine El Mousli, Claire Poujouly, Emilie Secret, Vincent Dupuis, Isabelle Le Potier, Marie-Emmanuelle Goriot, Julien Siracusa, Sébastien Banzet, Jean Gamby, Jean-Michel Siaugue

“…Optimization of the complementary DNA grafting protocol, carried out by varying the ratios between the quantities of dibenzocyclooctyne groups and DNA and between the quantities of DNA and MNP, revealed on the one hand that the quantity of DNA grafted per nanoparticle could be finely controlled, and on the other hand that the grafting on the MNP’s surface of an excessive quantity of dibenzocyclooctyne groups led to a reduction in grafting yields. …”
Get full text

Decreased brain-derived neurotrophic factor expression in chronic kidney disease: integrated clinical and experimental evidence by Juan Chen, Lili Fu, Mengjin Li, Kun Xie, Xinming Li, Xu-jie Zhou, Li Yang, Liming Zhang, Cheng Xue, Cheng Xue, Zhiguo Mao

“…This upregulation was validated in UUO mice by qPCR, showing a time-dependent increase in Bdnf-as expression at days 14 and 18 post-obstruction.ConclusionThis study integrated meta-analysis, murine model validation, and single-cell transcriptomic profiling to demonstrate a significant reduction of BDNF in CKD. …”
Get full text

Response of ozone to current and future emission scenarios and the resultant human health impact in Southeast Asia by Tingting Fang, Jie Hu, Yefu Gu, Joseph J.Y. Sung, Steve Hung Lam Yim

“…Our results show O3 in urban areas (i.e., Singapore, Jakarta, Kuala Lumpur, Bangkok, and Ho Chi Minh City) was sensitive to both nitrogen oxides (NOx) and volatile organic compounds (VOCs) emissions, and synergistic NOx and VOCs control is thus essential. Suburban, rural, and sea areas were under a NOx-limited regime, suggesting the high effectiveness of controlling NOx over these areas. …”
Get full text

Protective immunity induced by a novel P1 adhesin C-terminal anchored mRNA vaccine against Mycoplasma pneumoniae infection in BALB/c mice by Qilin Zeng, Peiyuan Sun, Weiwei Li, Yuanyuan Tang, Yuxuan Hu, Jun Zhou, Yanxia Zhou, Liesong Chen, Wu Yimou

“…Our research explores an mRNA vaccine candidate that targets the P1 adhesin of M. pneumoniae, a protein critical for the bacteria’s interaction with host cells. In a mouse model, this vaccine has shown potential by inducing immune responses and suggesting a possible reduction in inflammation, as indicated by changes in cytokine levels and lung pathology. …”
Get full text

Efficacy of therapeutic interventions for idiopathic recurrent pregnancy loss: a systematic review and network meta-analysis by Jorge Lima, Jorge Lima, João Guerreiro, Miguel Ângelo-Dias, Sofia Silvério Serra, Teresa Costa, Natália Marto, João Feldman de Pinho, João Costa, Rodrigo Ruano, Gonçalo Silva Duarte, Gonçalo Silva Duarte

“…References from key articles were also manually searched. Randomized controlled trials assessing the efficacy and safety of any prophylactic intervention that were conducted in adult women with RPL were included. …”
Get full text

Predictors of recurrence after conversion therapy in unresectable hepatocellular carcinoma treated with HAIC, bevacizumab, and sintilimab by Chang-Fu Liu, Xiao-Hui Zhao, Shi-Bo Zhu, Hai-Peng Yu, Wen-Ge Xing, Hui-Kai Li

“…The median RFS was 22.2 months (95% CI: 18.3–28.0); the 1- and 2-year RFS rates were 71.7% and 46.9%, respectively. The RCS model showed that an AFP decline greater than 25% and tumor size reduction significantly lowered the risk of 1-year recurrence, but reductions in tumor size beyond 60% did not confer additional benefits in reducing recurrence risk. …”
Get full text