Identification of Biomarkers Co-Associated with Lactylation and Acetylation in Systemic Lupus Erythematosus by Zhanyan Gao, Yang Feng, Chenghui Zheng, Fei Li, Zhan Sun, Mengmeng Xiang, Junrong Zhu, Mingyu Chu, Jinhua Xu, Jun Liang

“…In the training dataset (GSE81622), differential expression analysis was performed to compare SLE samples with healthy controls. …”
Get full text

Accuracy and Precision Evaluation of Image-Based Computer Assisted Surgical System for Total Ankle Arthroplasty by Matthew C. Rueff MSc, Zach Tupper, Matthew Hamilton PhD, Prudhvi Chinimilli, Scott Gulbransen, Laureline Prouvost, Edward T. Haupt MD, Laurent Angibaud, Dipl Ing.

“…The objective of the study was to evaluate the accuracy and precision of the TAA CAS system. Methods: TAA was performed by a board-certified, fellowship-trained orthopedic surgeon on twelve artificial ankle joint specimens (PN1132-3, Pacific Research) using a CAS system (ExactechGPS, Blue-Ortho) featuring a dedicated ankle application. …”
Get full text

Association between pan-immune-inflammation value and Serum Klotho levels: a cross-sectional analysis of renal function mediation by Mingjie Liu, Xuan Zhou, Han Xu, Yan Wang, Yuting Duan, Xiangru Guo, Bai Wei

“…Boruta feature selection method was used to identify variables included in the multivariable models. …”
Get full text

Impact of minimal self disorders on naturalistic episodic memory in first-episode psychosis and parallels in healthy individuals with schizotypal traits by Delphine Yeh, Sylvain Penaud, Alexandre Gaston-Bellegarde, Linda Scoriels, Linda Scoriels, Marie-Odile Krebs, Marie-Odile Krebs, Pascale Piolino

“…BackgroundSelf-disorders constitute a core feature of the schizophrenia spectrum, including early stages such as first-episode psychosis (FEP). …”
Get full text

Identification of Ion-kinetic Instabilities in Hybrid-PIC Simulations of Solar Wind Plasma with Machine Learning by Viacheslav M. Sadykov, Leon Ofman, Scott A. Boardsen, Yogesh, Parisa Mostafavi, Lan K. Jian, Kristopher Klein, Mihailo Martinović

“…In this work, we explore machine learning (ML) and deep learning (DL) classification models to identify unstable cases of ion VDFs driving kinetic waves. …”
Get full text

Are neurasthenia and depression the same disease entity? An electroencephalography study by Ge Dang, Lin Zhu, Chongyuan Lian, Silin Zeng, Xue Shi, Zian Pei, Xiaoyong Lan, Jian Qing Shi, Nan Yan, Yi Guo, Xiaolin Su

“…The essential feature contributing to the model was the theta connectivity. …”
Get full text

Deep learning-driven modality imputation and subregion segmentation to enhance high-grade glioma grading by Jiabin Yu, Qi Liu, Chenjie Xu, Qinli Zhou, Jiajun Xu, Lingying Zhu, Chen Chen, Yahan Zhou, Binggang Xiao, Lin Zheng, Xiaofeng Zhou, Fengming Zhang, Yuhang Ye, Hongmei Mi, Dongping Zhang, Li Yang, Zhiwei Wu, Jiayi Wang, Ming Chen, Zhirui Zhou, Haoyang Wang, Vicky Y. Wang, Enyu Wang, Dong Xu

“…Statistical analysis was performed using the Wilcoxon signed-rank test and the DeLong test. …”
Get full text

Prioritizing conservation patches in the coastal areas of Kal-Mehran sub-basin in Hormozgan province using a decision support tool by Azadeh Vaziri Nahad, Seyed Ali Jozi, Rokhshad Hejazi, Mohammad Reza Shokri, Saeid Malmasi

“…After preparing the 5 input files of Marxan software (planning unit file, conservation feature file, planning unit versus conservation feature file, boundary length file, and input parameters file), the software was run in the form of three scenarios designed with the goal of protecting 30, 50, and 100% of each criterion and the most suitable patches were introduced for conservation. …”
Get full text

Biomimetic UV photo-protection of skin surface by structured epicuticular wax films by Anuja Das, Luca Polacchi, Jean-Yves Fouron, Antoine Montaux-Lambert, Laurent Billon, Gustavo S. Luengo

“…Further, to showcase the feasibility of such approach for potential cosmetic applications, we replicate best performing structures on a commonly used model skin surface for UV absorption evaluation (polymethyl methacrylate plates) and on real ex-vivo Stratum Corneum, the outermost layer of skin. …”
Get full text

Characterisation of pregnancy-induced alterations in apolipoproteins and their associations with maternal metabolic risk factors and offspring birth outcomes: a preconception and l... by Li Chen, Karen Mei-Ling Tan, Melvin Khee-Shing Leow, Kok Hian Tan, Jerry Kok Yen Chan, Shiao-Yng Chan, Yap Seng Chong, Peter D. Gluckman, Johan G. Eriksson, Markus R. Wenk, Sartaj Ahmad Mir

“…Linear regression models and network analysis were implemented to investigate the association of apolipoproteins with maternal genetic variants, biochemical measures, metabolic risk factors, and offspring birth outcomes. …”
Get full text

High-affinity transferrin receptor binding improves brain delivery of bispecific antibodies at tracer dose by Gillian Bonvicini, Sunitha Singh, Lisa Sandersjöö, Tiffany Dallas, Eva Schlein, Amelia D. Dahlén, Sara Lopes van den Broek, Dag Sehlin, Ken G. Andersson, Stina Syvänen

“…In vivo pharmacokinetic analyses of radioiodinated bispecific antibodies and bapineuzumab in brain, blood and peripheral organs were performed over 7 days post-injection in WT mice and a model of Aβ pathology (App NL−G−F ). …”
Get full text

Sedative exposure and mortality in intracranial hypertensive tuberculous meningitis: a cohort study with propensity-score matching and machine learning analysis by Shijuan Cui, Fazheng Shen, Jianing Liang, Fan Li, Xiangyang Wang, Xin Liu, Haigang Chang

“…Primary outcomes included 200-day mortality assessed using multivariable logistic regression and Cox proportional hazards models. Propensity score matching (PSM) was performed to adjust for confounding, and machine learning (XGBoost) was used to predict mortality and evaluate feature importance.ResultsUnadjusted analyses identified age (odds ratio [OR] = 1.03 per year; 95% confidence interval [CI]: 1.01–1.05), sedative duration (OR = 1.13 per day; 95%CI: 1.04–1.22), and hospital length of stay (LOS; OR = 1.02 per day; 95%CI: 1.00–1.03) as significant mortality predictors. …”
Get full text

A systematic review and meta‐analysis of clinical signs, symptoms, and imaging findings in patients with suspected renal colic by Philipp Dahm, Alex Koziarz, Charles J. Gerardo, Daniel K. Nishijima, Jae Hung Jung, Simranjeet Benipal, Ali S. Raja

“…A literature search was performed using MEDLINE and EMBASE from inception to July 2, 2020. …”
Get full text

Discursive Strategies of Indirect Apology in English-Language Personal Communication by E. Yu. Ilyinova, O. S. Volkova, V. A. Litvinova

“…Linguistic-and-pragmatic analysis of direct and indirect apologies application stipulated the use of parametric modelling method, which involves building a model of communicative situation with the identification of constants, or parameters that vary and adapt to the circumstances of their use. …”
Get full text

P-69 EFFECTS OF POPULATIONAL-RELEVANT DOSES OF CARBOXYMETHYLCELLULOSE AND POLYSORBATE 80 EMULSIFIERS ON MASLD-ASSOCIATED HEPATOCARCINOGENESIS by GABRIEL BACIL PRATA, Julia Noveti Oliveira, Heloiza Ferreira Alves, Guilherme Romualdo Ribeiro, Luis Fernando Barbisan

“…A glucose tolerance test was performed and hepatic tumoral/non-tumoral and serum samples were collected. …”
Get full text

ATP6V0A4 as a novel prognostic biomarker and potential therapeutic target in oral squamous cell carcinoma by Xiaopu Gao, Jiamin Zhou, Yu Qiao, Chuyin Lin, Guanxiong Zhang, Qiuyu Wu, Zhikang Su, Qianji Zhang, Songkai Huang

“…For experimental validation, RT-qPCR was performed to measure ATP6V0A4 expression in OSCC cell lines, and plasmid transfection technology was used to establish overexpression models, followed by systematic evaluation of its regulatory effects on tumor cell proliferation, migration, and invasion. …”
Get full text

Research progress and prospects of biodegradable Zn–Fe alloys by Zhangzhi SHI, Shanpeng ZHAO, Kewei GAO, Zhe XUE, Shenglian YAO, Yingzhi CHEN, Jin ZHANG, Luning WANG

“…In addition, conducting long-term studies using large animal models is crucial to advance the clinical application of Zn–Fe alloy implants.…”
Get full text

Characterization of Different Types of Micro-Fission and Micro-Ionization Chambers Under X-Ray Beams by Juan Antonio Moreno-Pérez, Álvaro Marchena, Pablo Araya, Jesús J. López-Peñalver, Juan Alejandro de la Torre, Antonio M. Lallena, Santiago Becerril, Marta Anguiano, Alberto J. Palma, Miguel A. Carvajal

“…These models were calibrated using a photon beam in the X-ray spectrum. …”
Get full text

Discovery and Extensive Follow-up of SN 2024ggi, a Nearby Type IIP Supernova in NGC 3621 by Ting-Wan Chen, Sheng Yang, Shubham Srivastav, Takashi J. Moriya, Stephen J. Smartt, Sofia Rest, Armin Rest, Hsing Wen Lin, Hao-Yu Miao, Yu-Chi Cheng, Amar Aryan, Chia-Yu Cheng, Morgan Fraser, Li-Ching Huang, Meng-Han Lee, Cheng-Han Lai, Yu-Hsuan Liu, Aiswarya Sankar.K, Ken W. Smith, Heloise F. Stevance, Ze-Ning Wang, Joseph P. Anderson, Charlotte R. Angus, Thomas de Boer, Kenneth Chambers, Hao-Yuan Duan, Nicolas Erasmus, Michael Fulton, Hua Gao, Joanna Herman, Wei-Jie Hou, Hsiang-Yao Hsiao, Mark E. Huber, Chien-Cheng Lin, Hung-Chin Lin, Eugene A. Magnier, Ka Kit Man, Thomas Moore, Chow-Choong Ngeow, Matt Nicholl, Po-Sheng Ou, Giuliano Pignata, Yu-Chien Shiau, Julian Silvester Sommer, John L. Tonry, Xiao-Feng Wang, Richard Wainscoat, David R. Young, You-Ting Yeh, Jujia Zhang

“…Detailed light-curve modeling provides critical insights into the circumstellar material (CSM). …”
Get full text

Cervical ripening at home or in hospital during induction of labour: the CHOICE prospective cohort study, process evaluation and economic analysis by Mairead Black, Cassandra Yuill, Mairi Harkness, Sayem Ahmed, Linda Williams, Kathleen A Boyd, Maggie Reid, Amar Bhide, Neelam Heera, Jane Huddleston, Neena Modi, John Norrie, Dharmintra Pasupathy, Julia Sanders, Gordon C S Smith, Rosemary Townsend, Helen Cheyne, Christine McCourt, Sarah Stock

“…The economic analysis involved a decision-analytic model from a National Health Service and Personal Social Services perspective, populated with CHOICE cohort and published data. …”
Get full text