Identification of m6 A-regulated ferroptosis biomarkers for prognosis in laryngeal cancer by Xin Wang, Wen Zhang, Kun Liang, Yujuan Wang, Jin Zhang, Jinping Wang, An Li, Yonggang Yun, Hiu Liu, Yanan Sun

“…Univariate Cox and least absolute shrinkage and selection operator (LASSO) regression were utilized for feature selection and risk model construction in the TCGA-HNSC dataset. …”
Get full text

Conservation of strain properties of bank vole-adapted chronic wasting disease in the absence of glycosylation and membrane anchoring by Enric Vidal, Hasier Eraña, Jorge M. Charco, Nuria L. Lorenzo, Samanta Giler, Montserrat Ordóñez, Eva Fernández-Muñoz, Maitena San-Juan-Ansoleaga, Glenn C. Telling, Manuel A. Sánchez-Martín, Mariví Geijo, Jesús R. Requena, Joaquín Castilla

“…Using a novel transgenic mouse model expressing I109 bank vole PrPC lacking the GPI anchor and largely devoid of glycans, we performed serial passages of CWD-vole prions. …”
Get full text

Research on cloud detection method based on voting ensemble learning using FY-4B satellite data by Jianhua Qu, Lingmeng Ye, Junjie Yan, Jinjing Sun, Ziyu Huyan

“…Cross-validation with MODIS data confirms >91% accuracy for the ensemble over deep sea, shallow water, land, and snow, with false alarm rates generally <8% (except 12% for snow). The ensemble performs stably across seasons. Compared to single models, the Voting Ensemble demonstrates markedly improved adaptability, accuracy, and robustness across diverse seasons and scenarios, offering a more reliable solution for complex cloud detection challenges.…”
Get full text

Evaluating machine learning pipelines for multimodal neuroimaging in small cohorts: an ALS case study by Shailesh Appukuttan, Shailesh Appukuttan, Aude-Marie Grapperon, Aude-Marie Grapperon, Mounir Mohamed El Mendili, Hugo Dary, Maxime Guye, Annie Verschueren, Jean-Philippe Ranjeva, Shahram Attarian, Wafaa Zaaraoui, Matthieu Gilson

“…Our findings reveal that, while certain pipeline components, such as subject-wise feature normalization, help improve classification outcomes, the overall influence of pipeline refinements on performance is modest. …”
Get full text

Mechanism of Anodic Dissolution of Tungsten in Sulfate–Fluoride Solutions by Martin Bojinov, Yoanna Penkova, Iva Betova, Vasil Karastoyanov

“…Voltametric and impedance data are successfully reproduced by a kinetic model featuring oxide growth and dissolution coupled with the recombination of point defects, as well as a multistep tungsten dissolution reaction at the oxide/electrolyte interface. …”
Get full text

Analysis of the Arc Quenching System of an Arrester Operation Based on a Flow Ultrasound Generator by Matvey I. Apolinskiy, Vladimir Ya. Frolov, Alexander D. Sivaev, Evgeniy Y. Enkin

“…This article is devoted to the analysis of the arrester operation, which has design features of flow ultrasound generators. The paper includes both experimental investigations of the proposed spark gap arrester design and mathematical modeling of the processes occurring in it. …”
Get full text

Observations of Uranus at High Phase Angle as Seen by New Horizons by Samantha N. Hasler, L. C. Mayorga, William M. Grundy, Amy A. Simon, Susan D. Benecchi, Carly J. A. Howett, Silvia Protopapa, Heidi B. Hammel, Daniel D. Wenkert, S. Alan Stern, Kelsi N. Singer, Simon B. Porter, Pontus C. Brandt, Joel W. Parker, Anne J. Verbiscer, John R. Spencer, The New Horizons Planetary Science Theme Team

“…These results place new constraints on the atmospheric model of Uranus and its reflectivity. The observations are analogous to those from future exoplanet direct-imaging missions, which will capture unresolved images of exoplanets at partial phases. …”
Get full text

Himatanthus bracteatus stem bark ethanolic extract obtained by sequential pressurized liquid extraction: Chromatographic characterization and profiling of cytotoxic, antitumoral an... by Rose N. Pereira-Filho, Wilson D. Gonçalves-Júnior, Agenor G. dos Santos-Neto, John L.S. Cunha, Oslei P. de Almeida, Luciana N. Andrade, Daniela Droppa-Almeida, Ricardo G. Amaral, Cláudio Dariva, Juliana C. Cardoso, Patricia Severino, Eliana B. Souto, Ricardo L.C. de Albuquerque-Júnior

“…Chromatographic analysis revealed the major EEHB composition in dimethyl isoplumerideo acid, 13-deoxyplumerido, isoplumeride, and plumeride. Cytotoxicity was performed on MCF-7 and MCF-10A cell lines using MTT assay. …”
Get full text

The Design and Fabrication of a Ladder-Climbing Robot by Bathula Vineela Rathan, M. Tarun, P. H. J. Venkatesh, Y. Phaneendra

“…While some robots mimic human-like features, most are designed primarily for functionality rather than appearance. …”
Get full text

Prediction of porosity, hardness and surface roughness in additive manufactured AlSi10Mg samples. by Fatma Alamri, Imad Barsoum, Shrinivas Bojanampati, Maher Maalouf

“…For this purpose, data including porosity, surface hardness, and roughness were extracted from the literature, and additional measurements were performed on additive manufactured samples in the current work. …”
Get full text

Spatially explicit predictions using spatial eigenvector maps by Guillaume Guénard, Pierre Legendre

“…Abstract In this paper, we explain how to obtain sets of descriptors of the spatial variation, which we call “predictive Moran's eigenvector maps” (pMEM), that can be used to make spatially explicit predictions for any environmental variables, biotic or abiotic. It unites features of a method called “Moran's eigenvector maps” (MEM) and those of spatial interpolation, and produces sets of descriptors that can be used with any other modelling method, such as regressions, support vector machines, regression trees, artificial neural networks and so on. …”
Get full text

Risks, threats and mechanisms of management systems ESG-transformation by A. M. Margolin, I. V. Vyakina

“…Purpose: the article aims at justification and identification of the factors hindering the effective implementation of the management systems ESG-transformation, taking into account new risks and threats to sustainable development, and substantiation of the mechanisms that ensure its implementation.Methods: along with the traditional methods of scientific analysis, interdisciplinary approach typical for the study of sustainable development problems and the diagnosis of key factors associated with ESG-transformation of management systems, carried out a review of scientific literature, used various rating models, regulatory documents and guidelines for sustainable development, corporate social responsibility and diagnostics of ESG-factors.Results: the article performed diagnostics of managed and unmanaged risks of ESG-transformation of management systems, identified trends in the development of managerial personnel competencies that carry out such a transformation, and disclosed the features of achieving sustainable development goals. …”
Get full text

Assessment of carbon dioxide exchange processes between water bodies and the atmosphere by P.S. Korotkih, E.N. Neverov, I.A. Korotkiy

“…Calculating the precise volume of CO2 absorbed by the ocean is even more difficult due to the complex and dynamic nature of these processes. Some studies and models provide only an approximate assessment of the annual carbon balance between the atmosphere and the ocean. …”
Get full text

Complexity reduction by symmetry: Uncovering the minimal regulatory network for logical computation in bacteria. by Luis A Álvarez-García, Wolfram Liebermeister, Ian Leifer, Hernán A Makse

“…Symmetry principles play an important role in geometry, and physics, allowing for the reduction of complicated systems to simpler, more comprehensible models that preserve the system's features of interest. …”
Get full text

Forecasting Temperature Time Series Data Using Combined Statistical and Deep Learning Methods: A Case Study of Nairobi County Daily Temperature by John Kamwele Mutinda, Amos Kipkorir Langat, Samuel Musili Mwalili

“…Specifically, the VMD–ARIMA–GRU model emerged as the top performer, demonstrating the lowest error metrics and highest explanatory power. …”
Get full text

Rethinking Scanning Strategies With Vision Mamba in Semantic Segmentation of Remote Sensing Imagery: An Experimental Study by Qinfeng Zhu, Yuan Fang, Yuanzhi Cai, Cheng Chen, Lei Fan

“…However, CNNs are constrained by their restricted receptive fields, while ViTs face challenges due to their quadratic complexity. Recently, the Mamba model, featuring linear complexity and a global receptive field, has gained extensive attention for vision tasks. …”
Get full text

Unveiling GPT-4V's hidden challenges behind high accuracy on USMLE questions: Observational Study by Zhichao Yang, Zonghai Yao, Mahbuba Tasmin, Parth Vashisht, Won Seok Jang, Feiyun Ouyang, Beining Wang, David McManus, Dan Berlowitz, Hong Yu

“…ObjectiveThis study aimed to comprehensively evaluate the performance, interpretability, and limitations of GPT-3.5 Turbo, GPT-4, and its successor, GPT-4 Vision (GPT-4V), specifically focusing on GPT-4V’s newly introduced image-understanding feature. …”
Get full text

Circular RNA hsa_Circ_0007552 inhibits lung adenocarcinoma proliferation, migration and invasion via the miR-7974/BAP1 axis by Yanping Lin, Rong Li, Xin Shen, Mingjin Wu, Jiadai Tang, Jiangyan Guo, Caixin Yin, Tingrong Xia, Dongqi Li, Fengdi Hu, Yedan Liao, Rui Li, Lin Xie

“…Bioinformatics analysis and dual-luciferase reporter gene assays were conducted to validate the interactions among Circ_0007552, miR-7974, and BAP1. Western blot was performed to detect the protein expression of BAP1.ResultsCirc_0007552 exhibited low expression in LUAD tissues and cells, correlating with clinicopathological features such as tumor size, lymph node metastasis, clinical stage, and poor prognosis. …”
Get full text

In evolution’s unending race: ancestral STING sensors in Salmo salar mediate intracellular bacterial detection and programmed cell death through evolutionarily conserved pathways by Alejandro J. Yañez, Alejandro J. Yañez, Alejandro J. Yañez, Alejandro J. Yañez, Jorge F. Beltrán, Claudia A. Barrientos, Genaro Soto-Rauch, Marcelo Aguilar, Marcelo Aguilar, Adolfo Isla, Adolfo Isla, Adolfo Isla, Sandra N. Flores-Martin, Francisco T. Yañez, Yassef Yuivar, Adriana Ojeda, Felipe Almendras, Patricio Bustos, Marcos Mancilla

“…Although extensively characterized in mammals, its structural features and regulatory roles during intracellular bacterial infection in teleosts remain poorly defined.MethodsWe structurally characterized the ancestral STING ortholog from Atlantic salmon (Salmo salar) using AlphaFold-guided modeling to identify conserved motifs, including the cyclic dinucleotide (CDN)-binding cleft and phosphorylation regulatory sites. …”
Get full text

Estimation of aboveground biomass from spectral and textural characteristics of paddy crop using UAV-multispectral images and machine learning techniques by Sudarsan Biswal, Navneet Pathak, Chandranath Chatterjee, Damodhara Rao Mailapalli

“…This study focuses to estimate AGB of paddy crop by exploring the combined potential of spectral and textural features of unmanned aerial vehicle (UAV)-MS images using linear regression (LR), multi-linear regression (MLR), and random forest (RF) models. …”
Get full text