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T-cell receptor beta variable gene polymorphism predicts immune-related adverse events during checkpoint blockade immunotherapy
Published 2023-08-01“…However, they are associated with a unique spectrum of side effects, called immune-related adverse events (irAEs), which can cause significant morbidity and quickly progress to severe or life-threatening events if not treated promptly. …”
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1043
The effects of physical activity on adolescent psychological sub-health: chain-mediated effects of self-control and mobile phone addiction
Published 2025-02-01“…The findings indicate that (1) PA is negatively associated with both PSH and MPA, yet positively correlates with SC. …”
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1044
Relationship between physical literacy and mental health in adolescents: a moderated mediation model with resilience and physical activity as variables
Published 2025-02-01“…However, this mediation effect may fluctuate across individuals with different levels of physical activity. …”
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1045
Effect of potent nucleos(t)ide analog on alpha fetoprotein changes and occurrence of hepatocellular carcinoma in patients with chronic hepatitis B
Published 2025-02-01“…Abstract Background Successful antiviral therapy significantly decreases the incidence of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB). Alpha-fetoprotein (AFP) in the serum is a valuable early indicator of HCC. …”
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1046
Association between TyG related parameters and metabolic dysfunction associated fatty liver disease among nondiabetic individuals
Published 2025-02-01“…We found that there was a positive correlation between TyG index and the incidence of MAFLD as well as its related parameters in the nondiabetic population.…”
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Associations between hypovitaminosis D, adiposity indices and insulin resistance in adolescents: mediation analyses from NHANES 2011–2018
Published 2025-02-01“…However, the extent of adiposity’s mediating influence on the hypovitaminosis D-IR relationship among adolescents remains to be elucidated. …”
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Importance of underlying mechanisms for interpreting relative risk of Clostridioides difficile infection among antibiotic-exposed patients in healthcare facilities.
Published 2024-01-01“…We derive the mathematical relationship, using a deterministic model, between those parameters and observed equilibrium levels of colonization, CDI, and risk ratio of CDI among certain antibiotic-exposed patients relative to patients with no recent antibiotic exposure. …”
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The General Assembly Resolution ˝Protection of the Environment in Relation to Armed Conflicts˝ of 2022: Where We Stand 30 Years after
Published 2023-01-01“…After the adoption of the General Assembly Resolution ˝Protection of the Environment in Times of Armed Conflict˝ in 1992, this United Nations organ adopted another resolution on the subject matter in 2022 entitled ˝Protection of the Environment in Relation to Armed Conflicts˝. The new Resolution is a result of efforts made within the International Law Commission which issued its ˝Draft Principles on Protection of the Environment in Relation to Armed Conflicts, with Commentaries˝ in the same year. …”
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Disproportionality analysis of upadacitinib-related adverse events in inflammatory bowel disease using the FDA adverse event reporting system
Published 2025-02-01“…This study evaluates upadacitinib-related adverse events (AEs) utilizing data from the US Food and Drug Administration Adverse Event Reporting System (FAERS).MethodsWe employed disproportionality analyses, including the proportional reporting ratio (PRR), reporting odds ratio (ROR), Bayesian confidence propagation neural network (BCPNN), and empirical Bayesian geometric mean (EBGM) algorithms to identify signals of upadacitinib-associated AEs for treating inflammatory bowel disease (IBD).ResultsFrom a total of 7,037,004 adverse event reports sourced from the FAERS database, 37,822 identified upadacitinib as the primary suspect drug in adverse drug events (ADEs), including 1,917 reports specifically related to the treatment of inflammatory bowel disease (IBD). …”
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Physicochemical, Major Anions and Heavy Metals in Surface Water and Groundwater at Pb – Zn Mining areas of Ebonyi State, Nigeria
Published 2018-08-01“…Its shows that pH is generally low (3.65) resulting from the dissolution of the sulphide Ore. The heavy metal mean trend indicates that Fe > Zn >Pb> Cr >Cu > Ni > AS > Cd in the water samples. …”
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O-GlcNAc transferase mediates O-GlcNAcylation of NLRP3 regulates pyroptosis in spinal cord injury
Published 2025-03-01“…Objective: We investigated the implication of O-linked β-N-acetylglucosamine (O-GlcNAcylation) in regulating pyroptosis related proteins at the posttranslational level. Materials and methods: PC12 cells were stimulated with lipopolysaccharide (LPS). …”
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Assessment of asymptomatic fungal infections in COVID-19 positive and COVID-19 negative pneumonia: A comprehensive epidemiological analysis
Published 2025-01-01“…This single-center study explores asymptomatic fungal infections in COVID-19-positive and COVID-19-negative pneumonia cases, elucidating the intricate relationship between viral respiratory illnesses and fungal co-infections. …”
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Related studies on measuring the normal values of optic nerve sheath diameter in healthy Chinese adults based on CT scans
Published 2025-02-01“…Univariate linear regression analysis showed that gender (P < 0.001) and ETD (P < 0.001) were the influencing factors of the mean ONSD. Further multivariate linear regression analysis also showed that gender (P < 0.001) and ETD (P < 0.01) were associated with ONSD values. …”
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Identification of m6A methyltransferase-related WTAP and ZC3H13 predicts immune infiltrates in glioblastoma
Published 2025-02-01“…Functional disparities were determined through gene set enrichment analysis (GSEA). Tumor mutation burden (TMB) and immune checkpoint inhibitors (ICIs) were also analyzed. …”
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An Assessment of Heavy Metals in <i>Synodontis Clarias</i> (Linnaeus, 1766) from Ikpoba Reservoir, Benin City, Nigeria
Published 2013-07-01“…The mean concentrations of the heavy metals in fish were Cd (0.01mg/kg), Mn (2.38 – 2.54mg/kg), Cu (0.09 – 0.16mg/kg), Pb (0.03 – 1.25mg/kg), Zn(10.45 – 15.38mg/kg) and Cr (0.01 – 0.02 mg/kg). …”
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USP5 stabilizes YTHDF1 to control cancer immune surveillance through mTORC1-mediated phosphorylation
Published 2025-02-01“…Deficiency in YTHDF1 or USP5 increases PD-L1 expression and suppresses immune-related gene expression, facilitating immune evasion. …”
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The mediating role of parental attachment in the relationship between parenting styles and identity achievement among secondary and preparatory school students
Published 2023-06-01“… The purpose of this research was to examine the mediating role of parental attachment in the relationship between parenting styles and adolescents’ identity achievement. …”
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Obesity-related indices are associated with self-reported infertility in women: findings from the National Health and Nutrition Examination Survey
Published 2025-02-01“…Objective Obesity can contribute to infertility, but the exact relationship between infertility risk and obesity-related measurements like waist-to-height ratio (WHtR), body roundness index (BRI), conicity index (CoI), and A body shape index (ABSI) in women is uncertain. …”
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