Expanding Viral Diversity in Rice Fields by Next-Generation Sequencing by Wang Haoran, Chen Guoqing, Feng Guozhong

“…These analyses greatly expand our understanding of viruses in rice fields and provide valuable insights for developing efficient strategies to manage insect pests and virus-mediated rice diseases.…”
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Differential transport pathways of saturated and unsaturated fatty acid esters in male mouse hepatocytes by Fengwu Chen, Aizhen Yang, Yue Lu, Yuxin Zhang, Jingyu Zhang, Jianan Bu, Runlin Guo, Yue Han, Depei Wu, Yi Wu

“…Here, we find the secretion of UFA but not SFA esters is retarded in a male mouse hepatic endoplasmic reticulum (ER) stress model. Among 13 members of protein disulfide isomerase (PDI) family, only PDIA1 (PDI) deficiency leads to hepatosteatosis and hypolipidemia. …”
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Efficacy of a Blended Low-Intensity Internet-Delivered Psychological Program in Patients With Multimorbidity in Primary Care: Randomized Controlled Trial by Alicia Monreal-Bartolomé, Adoración Castro, M Ángeles Pérez-Ara, Margalida Gili, Fermín Mayoral, María Magdalena Hurtado, Esperanza Varela Moreno, Cristina Botella, Azucena García-Palacios, Rosa M Baños, Yolanda López-Del-Hoyo, Javier García-Campayo, Jesus Montero-Marin

“…Path analyses revealed that the intervention had a significant impact on the primary outcome, mediated by both positive and negative affect (positive affect: indirect effect=–0.15, bootstrapped 95% CI –0.28 to –0.03; negative affect: indirect effect=–0.14, bootstrapped 95% CI –0.28 to –0.02). …”
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GelMA@LNP/AST Promotes eNOS-Dependent Angiogenesis Through Autophagy Activation for the Treatment of Hind Limb Ischemia by Lai L, Wu H, Peng L, Zhang Z, Wu X, Zheng S, Su Z, Chu H

“…Although some studies have evaluated the effects of using bioactive factors to promote neovascularization and tissue repair, the clinical outcomes have not met expectations, possibly due to the difficulties in maintaining biological activity and avoiding potential side effects. …”
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4-1BB agonist targeted to fibroblast activation protein α synergizes with radiotherapy to treat murine breast tumor models by Ignacio Melero, Alvaro Teijeira, Christian Klein, Maria E Rodriguez-Ruiz, Christina Claus, Pablo Umana, Tamara Tanos, Carlos E De Andrea, Carlos Luri-Rey, Paloma Sanchez-Mateos, Leticia Fernández-Rubio, María Collantes, Irantzu Serrano-Mendioroz, Celia Barrio-Alonso, Antonio Rullan, Jon Ander Simon, Eneko Garate-Soraluze, Claudia del Pilar Herrero

“…Selective monoclonal antibody (mAb)-mediated depletions of immune cell populations, neutralizing interferon alpha/beta receptor 1 (IFNAR-I) IFNAR and interferon (IFN)-γ mAbs and gene-modified mice (4-1BB−/−) were used to delineate the immune cell subsets and mechanisms required for efficacy. 67Ga labeled muFAP-4-1BBL tracked by SPECT-CT was used to study biodistribution. …”
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Conflicts and Political Instability in Sudan: A Re-visit Discourse by Efe Ann Ijoyah

“…The study revealed that African Union was the first body to intervene in the crisis through mediation and sending of troops in July 2004 before the United Nations st took over the mission in 31 December, 2007. …”
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Bienestar psicológico y ansiedad competitiva: el papel de las estrategias de afrontamiento / Competitive Anxiety and Psychological Well-being: the Role of Coping Strategies by Enrique Cantón-Chirivella, Irene Checa-Esquiva, María Yolanda Vellisca-González

“…The results predict, through regression analysis, the possibility of experiencing anxiety and psychological well-being in the competitive context, regulated by the mediator of task-directed coping strategies. …”
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Cadmium exposure increases insecticide sensitivity of Sogatella furcifera (Horváth) by decrease the diversity of symbiotic bacteria by Yanfei Zhu, Yu Wu, Xiangjie Li, Yujie Li, Zichao Zheng, Qiao Gao, Wenbing Ding, Hualiang He, Lin Qiu, Youzhi Li

“…This study provides new insights into the symbiotic bacteria mediated increase in insecticide sensitivity due to heavy metal exposure, providing a foundation for utilizing compounds that disturb symbiotic bacteria balance in pest for pest control.…”
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Integration of metabolomic and transcriptomic analyses reveals regulatory functions of the ChREBP transcription factor in energy metabolism by Jie An, Inna Astapova, Guofang Zhang, Andrew L. Cangelosi, Olga Ilkayeva, Hannah Marchuk, Michael J. Muehlbauer, Tabitha George, Joseph Brozinick, Mark A. Herman, Christopher B. Newgard

“…Integrated transcriptomic and metabolomic analyses in rats with GalNac-siRNA-mediated suppression of ChREBP expression in liver reveal other ChREBP functions. …”
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Mental health literacy of Greek teachers: Highlighting critical factors for identifying and supporting students in need by Eleftheria Spyropoulou, Christina Athanasiades, Ariadni Stogiannidou, Elias Kourkoutas

“… The study aimed to investigate the level of teachers’ literacy and comfort in relation to mental health issues of children and youth, as well as to highlight the factors that affect teachers’ mental health literacy. …”
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Chemical characterization of Siraitia grosvenorii granules and their efficacy and mechanism of action on PM2.5-induced acute lung injury by Qi Shao, Yan Zhao, YuYu Shi, Fafeng Cheng, ZeHan Zhang, Ying Liu, ChangXiang Li, ZiLin Ren, Hua Bai, Haojie Cheng, Rolando Maddela, Junqiang Tian, Xueqian Wang

“…However, SGG reversed these changes, particularly tissue damage and oxidative stress, suggesting that lung protection is mediated by the antioxidant effect, which mitigates the release of alarmin and inflammation.…”
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Aflatoxin B1 impairs the growth and development of chicken PGCs through oxidative stress and mitochondrial dysfunction by Ying-Jie Niu, Jun Wu, Wenjie Ren, Guangzheng Liu, Gaoyuan Wu, Yixiu Peng, Dan Zheng, Kai Jin, Qisheng Zuo, Guohui Li, Wei Han, Xiang-Shun Cui, Guohong Chen, Bichun Li

“…Interestingly, we found that the NRF2-mediated antioxidant pathway was activated in AFB1-treated PGCs. …”
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Lockdown to Contain the COVID-19 Pandemic: An Opportunity to Create a Less Polluted Environment in India by Preet Lal, Amit Kumar, Supriya Bharti, Purabi Saikia, Dibyendu Adhikari, M. L. Khan

“…The five megacities observed a sharp decline in the daily mean concentration of PM2.5 (ca. 32% (Delhi) to 59.62% (Bengaluru) during the lockdown 2020 as compared to the analogous period of lockdown in 2019. …”
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A split intein and split luciferase-coupled system for detecting protein-protein interactions by Zhong Yao, Jiyoon Kim, Betty Geng, Jinkun Chen, Victoria Wong, Anna Lyakisheva, Jamie Snider, Marina Rudan Dimlić, Sanda Raić, Igor Stagljar

“…We previously developed a sensitive method, Split Intein-Mediated Protein Ligation (SIMPL), for detecting binary PPIs via irreversible splicing of the interacting proteins being investigated. …”
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Susy at the FPF by Luis A. Anchordoqui, Ignatios Antoniadis, Karim Benakli, Jules Cunat, Dieter Lüst

“…We show that using next generation LHC experiments currently envisioned for the Forward Physics Facility (FPF) we could search for signals of neutrino-modulino oscillations to probe models with string scale in the grand unification region and SUSY breaking driven by sequestered gravity in gauge mediation. This is possible because of the unprecedented flux of neutrinos to be produced as secondary products in LHC collisions during the high-luminosity era and the capability of FPF experiments to detect and identify their flavors.…”
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Dimethyl fumarate promotes the degradation of HNF1B and suppresses the progression of clear cell renal cell carcinoma by Yue Dai, Hongchen Li, Shiyin Fan, Kai Wang, Ziyi Cui, Xinyu Zhao, Xue Sun, Mingen Lin, Jiaxi Li, Yi Gao, Ziyin Tian, Hui Yang, Bingbing Zha, Lei Lv, Yanping Xu

“…Furthermore, HNF1B interacts with and stabilizes Yes-associated protein (YAP), thus DMF-mediated HNF1B degradation decreases YAP protein level and the expression of its target genes, resulting in the suppression of ccRCC cell proliferation. …”
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Competing stakeholder discourses in constructing cultural heritage: The legal case of the house at No. 98 Hai’er Lane, China by Zhonghua Wu, Jian Li

“…., adopting a multi-stakeholder approach to mediate various interests of stakeholders. Besides, disputes over heritage protection and promotion need to be understood within the dominant discourses of their time. …”
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Molecular mechanisms in liver repair and regeneration: from physiology to therapeutics by Xiao Ma, Tengda Huang, Xiangzheng Chen, Qian Li, Mingheng Liao, Li Fu, Jiwei Huang, Kefei Yuan, Zhen Wang, Yong Zeng

“…Abstract Liver repair and regeneration are crucial physiological responses to hepatic injury and are orchestrated through intricate cellular and molecular networks. …”
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A visual cortical-lateral posterior thalamic nucleus circuit regulates depressive-like behaviors in male mice by Fangfang Wu, Chenxi Gu, Rui Xu, Junwei Ma, Lei Gao, Youjiao Zhang, Siyuan Bu, Qingbo Lu, Te Zhao, Yijun Han, Chen Guo, Yihui Cui, Jianhua Ding, Gang Hu, Zhijun Zhang

“…However, the precise circuits mediating the impact of V1 on depressive-like behaviors are poorly understood. …”
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Desmoplastic reaction in the microenvironment of head and neck and other solid tumors: the therapeutic barrier by Kohei Okuyama, Maiko Tsuchiya, Kala Chand Debnath, Shajedul Islam, Souichi Yanamoto

“…DR promotes epithelial-mesenchymal transition and cancer cell invasion through CAF-mediated extracellular matrix remodeling and signaling pathways such as transforming growth factor-beta. …”
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