The Foreign Commission of the Soviet Writers’ Union in 1950s-1960s: Boundaries, Obstacles, Tricks, Embarrassment, Impact by Kristina Buynova

“… In the 1950s and 1960s, the Foreign Commission of the Soviet Writers’ Union occupied the niche of mediator in relations between Western literature and the USSR. …”
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Remote cooling of spin-ensembles through a spin-mechanical hybrid interface by Yang Wang, Durga Bhaktavatsala Rao Dasari, Jörg Wrachtrup

“…These results not only contribute to the development of a practical solution for cooling/polarizing large spin ensembles but also provide a relatively simple means of tuning the dynamics of a hybrid system. …”
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Multi-locus CRISPRi targeting with a single truncated guide RNA by Molly M. Moore, Siddarth Wekhande, Robbyn Issner, Alejandro Collins, Anna J. Cruz, Yanjing V. Liu, Nauman Javed, Salvador Casaní-Galdón, Jason D. Buenrostro, Charles B. Epstein, Eugenio Mattei, John G. Doench, Bradley E. Bernstein, Noam Shoresh, Fadi J. Najm

“…These truncated guides direct CRISPRi-mediated deposition of repressive H3K9me3 marks and disrupt transcription factor binding at most sequence match target sites. …”
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Case Report: Dangerous liaisons between splenectomy and eltrombopag-induced chronic thromboembolic pulmonary hypertension in patients with immune thrombocytopenia: report of two ca... by Roberto Castelli, Enrico Atzori, Alessandro Palmerio Delitala, Salvatore Antonio Masala, Valentina Micheluzzi, Enrico Ponti, Enrico Ponti, Giuseppe Sanna, Dante Castro, Antonio Gidaro, Mattia Donadoni, Roberto Manetti, Pierluigi Merella, Nicia Isabella Profili, Andrea Maria D'Armini, Gavino Casu, Gavino Casu

“…IntroductionPrimary immune thrombocytopenia is an autoimmune bleeding disorder characterized by variable immune-mediated platelet destruction. These patients have reported thrombotic complications, both venous and arterial, in addition to bleeding. …”
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Role of mitochondrial and lysosomal dysfunction in acute pancreatitis pathogenesis by Yuliya V Yevsyutina, V. T. Ivashkin, E. Z. Abgadzhava

“…Hyperamilasemia, premature intralobular activation of digestive enzymes, accumulation of large vacuoles in acinar cells, activation of proinflammatory mediators, apoptosis and necrosis of acinar cells are the basic pathomorphological signs of AP. …”
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Attenuation processes in positive social emotion upregulation: Disentangling functional role of ventrolateral prefrontal cortex by Dmitriy D. Bezmaternykh, Mikhail Ye. Melnikov, Evgeny D. Petrovskiy, Ksenia G. Mazhirina, Andrey A. Savelov, Mark B. Shtark, Patrik Vuilleumier, Yury Koush

“…Here, we examined the neural processes mediating upregulation of positive social emotions using functional magnetic resonance imaging in healthy female volunteers. …”
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An oligodendrocyte silencer element underlies the pathogenic impact of lamin B1 structural variants by Bruce Nmezi, Guillermo Rodriguez Bey, Talia DeFrancesco Oranburg, Kseniia Dudnyk, Santana M. Lardo, Nathan Herdman, Anastasia Jacko, Sandy Rubio, Emanuel Loeza-Alcocer, Julia Kofler, Dongkyeong Kim, Julia Rankin, Emma Kivuva, Nicholas Gutowski, Katherine Schon, Jelle van den Ameele, Patrick F. Chinnery, Sérgio B. Sousa, Filipe Palavra, Camilo Toro, Filippo Pinto e Vairo, Jonas Saute, Lisa Pan, Murad Alturkustani, Robert Hammond, Francois Gros-Louis, Michael S. Gold, Yungki Park, Geneviève Bernard, Raili Raininko, Jian Zhou, Sarah J. Hainer, Quasar S. Padiath

“…This element consists of CTCF binding sites that mediate three-dimensional chromatin looping involving LMNB1 and the recruitment of the PRC2 transcriptional repressor complex. …”
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Gen inhibiting the Wnt/Ca2+ signaling pathway alleviates cerebral ischemia/reperfusion injury by Li Li, Saisai Liu, Mengzhe Wang, Mengjia Li, Yi Liu, Haili Chen, Jie Chen, Weiting Tao, Li Huang, Shidi Zhao

“…The knockdown of Frizzled-2 confirmed the pathway’s role in mediating calcium overload and subsequent damage. Our findings suggest that Gen alleviates CIRI by inhibiting the Wnt/Ca2+ signaling pathway, positioning it as a promising candidate for therapeutic intervention in stroke treatment.…”
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Network pharmacology study on the mechanism of berberine in Alzheimer’s disease model by Yaoyi Zhang, Shuai Lv, Pinyuan Huang, Lingmin Xiao, Nan Lin, En Huang

“…It also promotes PPARG expression to blockage of NF-κB pathway-mediated inflammatory response and neuroinflammation.…”
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Prenatal exposure to bisphenol A causes reproductive damage in F1 male rabbits due to inflammation and oxidative stress by Qianhui Zhao, Jialu Pan, Yongzhan Bao, Xiao Wang, Wanyu Shi

“…By modulation of the Nrf2 and NF-κB axes, BPA could influence the expression of antioxidant enzymes and inflammatory mediators in the rabbit reproductive system, leading to cell apoptosis and tissue damage. …”
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Methodical approaches in experimental modelling of non-alcoholic fatty liver disease by N. V. Bivalkevich, Yu. K. Denisenko, T. P. Novgorodtseva

“…Today‘s methods of NAFLD modelling can be divided into two extensive groups: induction of liver disease by genetic mutation, and phenotypic development of NAFLD due to alimentary factor. …”
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Patient with Jaundice, Dyspnea and Hyperferritinemia after COVID-19 by V. R. Grechishnikova, P. E. Tkachenko, M. S. Zharkova, T. P. Nekrasova, V. T. Ivashkin

“…Laboratory tests revealed signs of hepatic insufficiency, markers of cholestasis and inflammation persisted in time. …”
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Mulheres nas ciências, engenharia e tecnologia: o que as publicações científicas apontam? by Marina Gomes Murta Moreno, Cíntia Maria Gomes Murta

“…Apesar de serem crescentes os debates sobre a questão, justifica-se o atual estudo bibliométrico frente à carência de pesquisas de levantamentos numéricos e de avaliação de tendências das publicações sobre o tema. …”
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Incidence rate and associated patient characteristics of liver disease in Wales 2004–2022: a retrospective population-scale observational study by Ashley Akbari, Andrew Yeoman, Haroon Ahmed, Jingwei Gao, Aled Davies, Thomas Peter Ignatius Pembroke

“…A total of 79 992 individuals (72%) entered the cohort with the underlying aetiology of liver disease, including alcohol-related liver disease, non-alcoholic fatty liver disease (NAFLD), viral hepatitis, metabolic, haemochromatosis and autoimmune liver diseases. …”
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Local control and recurrence patterns after stereotactic irradiation delivered in more than 4 fractions for hepatocellular carcinomas and liver metastases: a retrospective study by Alizée Renan, Marie Bruand, Maria Jolnerovski, Aboubacar Diallo, Nicolas Demogeot

“…This study evaluated LC and recurrence patterns in patients administered hepatic SBRT in more than 4 fractions due to dosimetric constraints. …”
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Case study on SAF emissions from air travel considering emissions modeling impact by Hakkı Aksoy, María García Domene, Parthiban Loganathan, Simon Blakey, Elias Zea, Ricardo Vinuesa, Evelyn Otero

“…The environmental impact of air travel, largely driven by fossil-fuel consumption, remains a critical subject of debate. Addressing this challenge requires immediately adopting sustainable practices to mitigate its environmental footprint. …”
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The type of infections and the use of antibiotics among patients with rheumatoid arthritis: A review by Asma D. Alshammari, Mona Matar Aldhafeeri, Amal M. Aldhafeeri, Maram Asaad Alanzi, Maha Bandar Almutairi, Jawaher Abdullah Alrasheedi, Thikra Adel Alsurur, Aeshah Dhahawi Alshammri

“…In all patients with rheumatoid arthritis, it is necessary to conduct initial screenings for hepatitis B virus and tuberculosis. Additionally, it is important to administer vaccinations for specific pathogens (such as pneumococcal, herpes zoster, and influenza) before and during treatment. …”
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Desarrollo de nuevos diseños vegetales: Mejora genética vs transformación genética y edición génica by Pedro Martínez Gómez

“…El binomio ciencia-opinión pública, está también más que presente en el debate de esta cuestión; además de la persuasión en ambos bandos a favor y en contra de los cultivos modificados. …”
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A 19-year-old Patient with Recurrent Pruritus and Jaundice by K. S. Nezhdanov, E. N. Shirokova, Yu. O. Shulpekova, A. S. Ostrovskaya, M. S. Zharkova, V. T. Ivashkin

“…Blood chemistry results revealed an elevation of total bilirubin (up to 634 μmol/L), direct bilirubin (up to 354 μmol/L), bile acids (up to 510 μmol/L) and normal gamma glutamyl transferase level. Workup was negative for viral hepatitis, autoimmune liver diseases, obstructive choledochal lesions, storage diseases, although mutation in gene ABCB11 was found. …”
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The touristification of urban spaces: measurement proposal by Manuel De la Calle Vaquero, Carmen Mínguez García, María García Hernández

“…La recuperación turística postpandemia sitúa de nuevo estos procesos en primera línea de debate. Este texto reflexiona sobre las posibilidades de medición de la turistificación del espacio urbano. …”
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