Impact of re-operation on progression-free survival in patients with recurrent GBM: Experience in a tertiary referral center. by Houssein Darwish, Tasnim Diab, Sarah Kawtharani, Mounir Barake, Bader Ali, Nagham Ramadan, Hiba Fadlallah, Jeannot Kekedjian, Marwan Najjar, Hazem I Assi

“…The aim of this study is to assess whether reoperation for recurrent GBM offers a survival benefit compared to patients who do not undergo re-resection and to identify the prognostic factors influencing patient selection for reoperation.<h4>Methods</h4>This study retrospectively reviewed medical records from the American University of Beirut Medical Center over a ten-year period, from 01/01/2012 to 01/01/2023. …”
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The association of triglyceride-glucose and triglyceride-glucose related indices with the risk of heart disease in a national by Xiaodi Tang, Kexin Zhang, Rong He

“…Existing evidence in Chinese people and in diabetes or non-diabetes patients regarding this association is limited, highlighting the need for further investigation. Methods A cohort study was conducted involving 7945 participants enrolled in the China Health and Retirement Longitudinal Study (CHARLS). …”
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Pathological and radiological assessment of benign breast lesions with BIRADS IVc/V subtypes. should we repeat the biopsy? by Wesam Rjoop, Anwar Rjoop, Alia Almohtaseb, Lama Bataineh, Zeina Nser Joubi, Maha Gharaibeh, Abdalrahman Al-Qwabah, Yousef Alasheh, Ismail Matalka

“…This study aimed to identify the histopathological diagnosis of benign breast masses classified into BIRADS IVc and V subgroups, investigate the radiological characteristics of these masses, and identify ultrasound features that could lead to false positive results (benign lesions that mimic malignancy on imaging). Methods This was a retrospective cross-sectional study at a single facility. …”
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Preventing epileptogenesis by interaction between inositol isomers and proteins by Lia Tsverava, Luka Kharkhelauri, Vincenzo Lagani, Giorgi Gamkrelidze, Veriko Bokuchava, Tamar Kiguradze, Merab Kokaia, Revaz Solomonia

“…This study seeks to address these gaps. Methods Inositol interacting proteins were identified by cellular thermal shift assay. …”
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A pilot cluster randomized controlled trial assessing uptake of PrEP and contraception in hair salons in South Africa by Ingrid V. Bassett, Joyce Yan, Sabina Govere, Sthabile Shezi, Lungile M. Ngcobo, Shruti Sagar, Jana Jarolimova, Dani Zionts, Anele Khumalo, Zinhle Zwane, Christina Psaros, Nduduzo Dube, Robert A. Parker

“…Our objective was to assess the uptake of PrEP and contraception in hair salons in South Africa. Methods We conducted a pilot cluster randomized controlled trial to evaluate uptake of a hair stylist-initiated, nurse-supported intervention offering a dynamic choice of contraception (oral or injectable), STI testing and treatment, and oral PrEP in 3 salons in urban KwaZulu-Natal. …”
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Atopic Dermatitis Treatments Before and After Initiation of Ruxolitinib Cream: 6-Month Follow-Up Analysis of a US Payer Claims Database by Liu J, Desai K, Teng CC, Sturm D, Stockbower G, Patadia H, Willey V

“…This analysis describes treatment patterns before and after initiation of ruxolitinib cream among patients with AD.Patients and Methods: This retrospective, observational study used medical and pharmacy claims data from the Healthcare Integrated Research Database (HIRD®) and included adults and adolescents (aged ≥ 12 years) with an AD diagnosis, a first claim for ruxolitinib cream (index date) between October 2021 and July 2022, and continuous enrollment in a commercial or managed Medicare plan for 6 months before and after the index date. …”
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Efficacy of medical thoracoscopy combined with fibrinolytic therapy in the treatment of complicated parapneumonic effusions and empyema by Feng-Fu Zhan, Mao-Hong Huang, Yan-Ping Du, Yan Chen, Han-Han Chen, Yi-Li Lin, Yi-Yuan Chen, Ling Cai, Xiao-Bin Zhang

“…Abstract Objective This study aimed to evaluate the clinical efficacy, safety, and feasibility of medical thoracoscopy combined with fibrinolytic therapy for the treatment of complicated parapneumonic effusions and empyema, with a focus on therapeutic outcomes and recovery duration. Methods A retrospective cohort study was conducted involving 108 patients treated at Zhongshan Hospital, Xiamen University, between January 2015 and May 2024. …”
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Data-Sharing Statements Requested from Clinical Trials by Public, Environmental, and Occupational Health Journals: Cross-Sectional Study by Yingxin Liu, Jingyi Zhang, Lehana Thabane, Xuerui Bai, Lili Kang, Gregory Y H Lip, Harriette G C Van Spall, Min Xia, Guowei Li

“…ObjectiveThis study aims to investigate whether public, environmental, and occupational health journals requested data-sharing statements from clinical trials submitted for publication. MethodsIn this bibliometric survey of “Public, Environmental, and Occupational Health” journals, defined by the Journal Citation Reports (as of June 2023), we included 202 journals with clinical trial reports published between 2019 and 2022. …”
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A Pragmatic Clinical Trial to Compare the Real-World Effectiveness of V-Go versus Standard Delivery of Insulin in Patients with Advanced Type 2 Diabetes by Mark J. Cziraky, Scott Abbott, Matt Nguyen, Kay Larholt, Elizabeth Apgar, Thomas Wasser, Poul Strange, Leon Shi, H. Courtenay Harrison, Beverly Everitt, Lynn Nowak

“…**Objective:** This prospective pragmatic clinical trial evaluated V-Go, a wearable insulin delivery device, compared with standard treatment optimization (STO) among insulin-treated patients with T2DM in a realworld, community-based practice setting. **Methods:** Study sites, rather than individual patients, were randomized to V-Go or STO via cluster randomization. …”
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Outcomes, Healthcare Resource Utilization, and Costs of Overall, Community-Acquired, and Hospital-Acquired Acute Kidney Injury in COVID-19 Patients by Jay L. Koyner, Rachel H. Mackey, Ning A. Rosenthal, Leslie A. Carabuena, J. Patrick Kampf, Paul McPherson, Toni Rodriguez, Aarti Sanghani, Julien Textoris

“…**Objectives:** To quantify the burden of AKI, CA-AKI, and HA-AKI among inpatients with COVID-19. **Methods:** This retrospective cohort study included inpatients with COVID-19 discharged from US hospitals in the Premier PINC AI™ Healthcare Database April 1–October 31, 2020, categorized as AKI, CA-AKI, HA-AKI, or no AKI by ICD-10-CM diagnosis codes. …”
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Enhancing Semi-Supervised Learning With Concept Drift Detection and Self-Training: A Study on Classifier Diversity and Performance by Jose L. M. Perez, Roberto S. M. Barros, Silas G. T. C. Santos

“…Additionally, it introduces a self-training approach to provide more labels and optimize model learning and adaptation. This research also details updates in the Massive Online Analysis (MOA) framework, that supports the simulation of semi-supervised scenarios. …”
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Survey of medication history of patients with stroke after discharge from an acute hospital ward: a case series study by Yuko Fukuda, Risa Ito, Misaki Kakihana, Tsutomu Takahashi, Tetsuji Kanemoto, Toshiyuki Sahara, Masahiko Tsujikawa, Mitsuko Onda

“…This study aimed to clarify medication continuity, particularly for medications adjusted during hospitalization that should be continued even after discharge, by investigating the medication use histories of patients with stroke transferred from acute care hospitals to outpatient hospitals. Methods We enrolled patients who were discharged from an acute ward between June 11, 2022, and March 31, 2023, after receiving inpatient care at the Japan Community Healthcare Organization, Hoshigaoka Medical Center for acute stroke, and transferred to other outpatient hospitals. …”
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Disproportionality analysis of upadacitinib-related adverse events in inflammatory bowel disease using the FDA adverse event reporting system by Shiyi Wang, Xiaojian Wang, Jing Ding, Xudong Zhang, Hongmei Zhu, Yihong Fan, Changbo Sun

“…This study evaluates upadacitinib-related adverse events (AEs) utilizing data from the US Food and Drug Administration Adverse Event Reporting System (FAERS).MethodsWe employed disproportionality analyses, including the proportional reporting ratio (PRR), reporting odds ratio (ROR), Bayesian confidence propagation neural network (BCPNN), and empirical Bayesian geometric mean (EBGM) algorithms to identify signals of upadacitinib-associated AEs for treating inflammatory bowel disease (IBD).ResultsFrom a total of 7,037,004 adverse event reports sourced from the FAERS database, 37,822 identified upadacitinib as the primary suspect drug in adverse drug events (ADEs), including 1,917 reports specifically related to the treatment of inflammatory bowel disease (IBD). …”
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The Effect of Rosuvastatin on a murine model of deep vein thrombosis by Megan E. Barney, Shenghao Zhou, Anh Le-Cook, Naly Setthavongsack, Gabriel Nager, Jennifer M. Loftis, Randy L. Woltjer, Monica Hinds, Khanh P. Nguyen

“…We hypothesize that statins may reduce the inflammation that may be associated with the development of post thrombotic syndrome (PTS). Materials and methods: Wildtype CD1 mice were fed either regular chow or 1 mg/kg rosuvastatin diets for 1 week prior to surgically induced DVT. …”
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Enhanced antitumor activity of combined hepatic arterial infusion chemotherapy with Lenvatinib and PD-1 inhibitors in unresectable hepatocellular carcinoma: a meta-analysis by Lingling Zhao, Cheng Xu, Jiewen Deng, Yang Ni

“…This meta-analysis aims to assess whether the integration of HAIC with lenvatinib and PD-1 inhibitors (referred to as the HAIC-L-P group) leads to better treatment effectiveness and security compared to lenvatinib and PD-1 inhibitors alone (L-P group) in uHCC.MethodsAn exhaustive search of the literature was conducted, including PubMed, the Cochrane Library, Embase, ClinicalTrials.gov, and Web of Science, from the start of each database until September 2024, to ensure a thorough and up-to-date compilation of relevant studies. …”
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Efficacy of non-surgical mechanical debridement with and without adjunct antimicrobial photodynamic therapy in the treatment of peri-implantitis among patients undergoing chemother... by Asma Saleh Almeslet, Malak Mohammed ALOsaimi, Chitra Jhugroo, Abdullah Faraj Alshammari, Darshan Devang Divakar, Cristalle Soman

“…The objective was to assess the efficacy of MD with and without adjunct aPDT in treating peri‑implantitis among patients undergoing chemotherapy. Methods: Patients with peri‑implantitis were included. …”
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A systematic review and meta-analysis of the impact of transcranial direct current stimulation on cognitive function in older adults with cognitive impairments: the influence of do... by Thatchaya Prathum, Thanwarat Chantanachai, Oranich Vimolratana, Chotica Laksanaphuk, Irin Apiworajirawit, Benchaporn Aneksan, Kanthika Latthirun, Cheng-Ta Yang, Wanalee Klomjai

“…This study further explores the impact of tDCS and its dosage parameters on cognitive enhancement in older people with cognitive impairments. Methods Randomized controlled trials (RCTs) published through November 2023 were retrieved from databases including PubMed, Scopus, EMBASE, EBSCO, and the Cochrane Library. …”
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Construction land transition in Qinghai-Tibet Plateau and its eco-environmental effects during 2000-2020 by ZHANG Zining, LUO Junqiang, ZHANG Peilei, RONG Han, LIU Haiyang, AN Shuang, CHANG Genying

“…In this context, the explicit morphological changes of construction land drive the transition of regional land use, and the ecological and environmental effects generated thereby deserve more attention. [Methods] Based on land use and remote sensing image data from 2000 to 2020, this study analyzed construction land transitions on the Qinghai-Tibet Plateau. …”
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The burden and outcomes of firearm injuries at two district-level emergency centres in Cape Town, South Africa: A descriptive analysis by L Bush, C Hendrikse, C Van Koningsbruggen, K Evans

“…To describe the burden of patients with firearm injuries and their outcomes at district-level emergency centres in the Western Cape. Methods. This study was a retrospective analysis of a prospectively collected database. …”
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‘I no longer worry about money for transport to the health centre’ - economic empowerment of caregivers of children living with HIV through Village Savings and Loan Associations: e... by Joseph Rujumba, Carmen Roebersen, Susan Namara, Richard Ochen, Sharon Eva Ahumuza, Allen Tushabe, Mathias Akugizibwe, David Bitira, Innocent Mwesigye, Stella Kentusi, Henry Zakumumpa, Japheth Kwiringira, Merian Natukwatsa Musinguzi

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