Validity, Agreement and Reliability of the ForceFrame Dynamometer in Patients with Anterior Cruciate Ligament Injury by Kamilla Arp, Thomas Frydendal, Troels Kjeldsen, Ulrik Dalgas, Signe Timm, Bjarke Viberg, Kim Ingwersen, Claus Varnum

“… # Study Design Cross-sectional study # Material and Methods Twenty-seven participants with ACL injury or reconstruction were recruited for participation in this study. maximal voluntary isometric contration (MVIC) of the knee extensors and flexors was tested on two separate days. …”
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Human Factors Studies to Assess the Usability of the Faricimab Prefilled Syringe by Barakat MR, Kwong Jr HM, Marcon G, O'Leary OE, Paris LP, Schneider P, Tang Y, Graff JM

“…Here, we report the usability of a novel faricimab 6 mg pre-filled syringe (PFS) configuration that has been designed specifically for intravitreal use.Patients and Methods: A simulated-use human factors validation study enrolling 15 retina specialists and 15 ophthalmic assistants was conducted in a market research facility configured to represent an ophthalmology clinic. …”
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Prothrombin complex concentrate for reversal of oral anticoagulants in patients with oral anticoagulation-related critical bleeding: a systematic review of randomised clinical tria... by Christian Ovesen, Jan Purrucker, Josefine Grundtvig, Theis Bech Mikkelsen, Christian Gluud, Janus Christian Jakobsen, Hanne Christensen, Thorsten Steiner

“…The aim of this systematic review was to evaluate the benefits and harms of prothrombin complex concentrate (PCC) in patients with oral anticoagulants-related critical bleeding. Methods For this systematic review CENTRAL, MEDLINE, Embase, LILACS, BIOSIS, Web of Science, and clinical trial registries were systematically searched. …”
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De la neuroplasticidad a las propuestas aplicadas: estimulación temprana y su implementación en Costa Rica / From Neuroplasticity to Applied Proposals: Early Stimulation and Its Im... by Johanna Sibaja-Molina, Tracy Sánchez-Pacheco, Mijail Rojas-Carvajal, Jaime Fornaguera-Trías

“…In addition, the theoretical and practical perspective of the ES practitioners is also described by detailing the empirical evidence around its most known/used variants in Costa Rica (i.e., Doman-Delacato, Snoezelen®, Point and Bebé políglota). …”
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New strategies in management of severe alcoholic hepatitis by P. Ye. Tkachenko, I. I. Komkova, M. V. Mayevskaya, V. T. Ivashkin

“…To evaluate efficacy and safety of S-adenosyl-L-methionine for treatment of alcohol-induced hepatitis of high severity.Material and methods. Overall 40 patients with severe alcoholic hepatitis from two medical centers were selected for the study. …”
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Exploratory study on the ascending pain pathway in patients with chronic neck and shoulder pain based on combined brain and spinal cord diffusion tensor imaging by Zhiqiang Qiu, Tianci Liu, Chengxi Zeng, Maojiang Yang, HongYing Yang, Xiaoxue Xu

“…ObjectiveTo explore the changes in the white matter microstructure of the ascending pain conduction pathways in patients with chronic neck and shoulder pain (CNSP) using combined brain and spinal cord diffusion tensor imaging techniques, and to assess its correlation with clinical indicators and cognitive functions.Materials and methodsA 3.0T MRI scanner was used to perform combined brain and spinal cord diffusion tensor imaging scans on 31 CNSP patients and 24 healthy controls (HCs), extracting the spinothalamic tract (STT) and quantitatively analyzing the fractional anisotropy (FA) and mean diffusivity (MD) which reflect the microstructural integrity of nerve fibers. …”
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Influence of minor hydrocarbon seepage on sulfur cycling in marine subsurface sediments by E. Schnabel, A. Vuillemin, C. C. Laczny, B. J. Kunath, A. R. Soares, A. J. Probst, R. Di Primio, J. Kallmeyer

“…Metagenomic and metatranscriptomic data indicated metabolic potential and activity towards sulfate reduction and anaerobic oxidation of methane (AOM). Expression of functional marker genes (<i>aprAB</i>, <i>dsrAB</i>, <i>mcrA</i>) revealed metabolic activities by sulfate-reducing Desulfobacterota and methanotrophic ANME-1 archaea sustained by HC traces in the sediment. …”
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Inpatient preferences among patients with multiple chronic conditions in China: A discrete choice experiment by Yueqin Wang, Shiyin Wu, Yuehua Chen, Ling Xiao, Qingling Su, Xiaoyin Huang, Weikang Wang, Wanxin Li, Shanshan Du, Wenbin Liu, Weimin Ye

“…Thus, this study aimed to identify the factors that affect MCC patients’ inpatient preferences and the extent to which these factors influence their decisions, thereby guiding inpatient service utilization among MCC patients. Methods Five attributes (institution scale, waiting time for hospital admission, presence of acquaintances, travel time from residence to hospital, and out-of-pocket expenses per visit) were identified to estimate inpatient choice for MCC patients through a discrete choice experiment. …”
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An App-Based Intervention With Behavioral Support to Promote Brisk Walking in People Diagnosed With Breast, Prostate, or Colorectal Cancer (APPROACH): Process Evaluation Study by Fiona Kennedy, Susan Smith, Rebecca J Beeken, Caroline Buck, Sarah Williams, Charlene Martin, Phillippa Lally, Abi Fisher

“…ObjectiveFollowing UK Medical Research Council guidelines, this study assessed the implementation of the intervention, examined the mechanisms of impact, and identified contextual factors influencing engagement. MethodsAdults (aged ≥18 y) with breast, prostate, or colorectal cancer who reported not meeting the UK guidelines for moderate-to-vigorous physical activity (≥150 min/wk) were recruited from a single hospital site in Yorkshire, United Kingdom. …”
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Internal Facilitation by Health Assistants for the &ldquo;WHO Lay Health Worker Dementia Care&rdquo; in Rural Uganda: A Formative Evaluation by Wakida EK, Obua C, Rukundo GZ, Samantha M, Maling S, Karungi CK, Talib ZM, Haberer J, Bartels SJ

“…To address these needs, we gathered key stakeholders’ perspectives on a culturally tailored model employing lay health workers, supported by health assistants as internal facilitators, to implement the World Health Organization dementia toolkit in rural communities.Methods: We conducted a formative qualitative study, utilizing one-on-one interviews with health assistants, district health team members, and primary healthcare providers in rural Uganda. …”
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A Comparison of Medial-congruent, Ultracongruent, and Cruciate-retaining Bearings Using a Single Cruciate-retaining Total Knee Design by Alexander V. Strait, MS, Eric J. Wilson, MD, Henry Ho, MS, Kevin B. Fricka, MD, Robert A. Sershon, MD

“…The aim of this study was to compare medial-congruent (MC), ultracongruent (UC), and cruciate-retaining (CR) TKA utilizing a single CR total knee system. Methods: Six surgeons performed 2883 primary TKAs from 2012 to 2022 using the same implant design, comprised of 708 MC, 799 UC, and 1376 CR bearings. …”
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Associations of carbohydrate quality and cardiovascular risk factors vary among diabetes subtypes by Katharina S. Weber, Sabrina Schlesinger, Janina Goletzke, Klaus Straßburger, Oana-Patricia Zaharia, Sandra Trenkamp, Robert Wagner, Wolfgang Lieb, Anette E. Buyken, Michael Roden, Christian Herder, for the GDS group

“…Abstract Background Assess the intake of carbohydrate quality and their association with cardiovascular risk factors among diabetes subtypes. Methods Participants of the German Diabetes Study (GDS) (recent-onset diabetes (n = 487) and 5-years thereafter (n = 209)) were allocated into severe autoimmune diabetes (SAID, 35%), severe insulin-deficient diabetes (SIDD, 3%), severe insulin-resistant diabetes (SIRD, 5%), mild obesity-related diabetes (MOD, 28%), and mild age-related diabetes (MARD, 29%). …”
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Budget Impact of Rivaroxaban for the Prevention of Thromboembolic Events after Hip or Knee Replacement in Spain by Xavier Granero Xiberta, Antonio Murcia, José Ricardo Troncoso Durán, Claudio Gómez Zubeldia, Aleix Llorac Moix, Ruth Graefenhain De Codes, Maria Giovana Ferrario, Luis Lizán

“…The aim of the study was to estimate the budget impact of increasing the use of rivaroxaban with respect to enoxaparin in the prophylaxis of VTE in patients undergoing elective THR or TKR. **Methods:** A budget impact analysis was conducted in order to estimate the economic cost from an increase of rivaroxaban use versus enoxaparin by 10%, 20%, and 30% over the 3 years of the time horizon (2015, 2016, and 2017) for the THR and TKR populations. …”
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The Role of Mature Brain-Derived Neurotrophic Factor and Its Precursor in Predicting Early-Onset Insomnia in Stroke Patients Experiencing Early Neurological Deterioration by Shi G, Yu P, Wang Z, Xu M, Guo M, Wang X, Zhou R

“…This study aimed to investigate the associations of serum mBDNF, proBDNF, and the mBDNF/proBDNF ratio with EOI in stroke patients experiencing END.Methods: In a prospective cohort study from October 2021 to December 2023, 232 stroke patients with END and 56 healthy controls (HCs) were enrolled. …”
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Incident prescriptions for common cardiovascular medications: comparison of recent versus pre-2020 medication adherence and discontinuation in three universal health care systems by Candace D. McNaughton, Peter C. Austin, Cynthia A. Jackevicius, Anna Chu, Jessalyn K. Holodinsky, Michael D. Hill, Colleen M. Norris, Mukesh Kumar, Noreen Kamal, Douglas S. Lee, Nadia Khan, Manav V. Vyas, Raed A. Joundi, Moira K. Kapral, Amy Y. X. Yu

“…Abstract Background Health system disruptions since onset of the COVID-19 pandemic may have adversely impacted adherence to medications for common cardiovascular risk factors. Methods We examined adherence to and discontinuation of incident prescriptions for medications treating hypertension, dyslipidemia, diabetes, and atrial fibrillation in Ontario, Alberta, and Nova Scotia, Canada. …”
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The associations between sedentary behavior and neck pain: a systematic review and meta-analysis by Yunchen Meng, Yaqi Xue, Sanjun Yang, Fang Wu, Yanyu Dong

“…Abstract Background This study aimed to systematically evaluate the associations between sedentary behavior (SB) in daily life and the risk of neck pain (NP), and to investigate the dose-response relationships between these variables across different populations, including variations in age, sex, occupation, and lifestyle practices. Methods We conducted a systematic literature search of PubMed, Web of Science, Scopus, and Embase for cross-sectional, cohort and case-control studies examining the association between SB and NP risk. …”
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Effects of Nontraditional Division III Lacrosse Participation on Movement Pattern Quality and Dynamic Postural Control by Christopher Rosenborough, Sean M. Collins, Edward Smith, Thomas G Bowman

“… # Design Cross-sectional laboratory study. # Methods Fifty men’s (age=19.38±1.24 years, height=182.63±6.16 cm, mass=82.37±8.46 kg) and 22 women’s (age=19.68±1.17 years, height=165.10±6.88 cm, mass=64.09±8.72 kg) lacrosse players were recruited. …”
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Social Media Use and Oral Health–Related Misconceptions in Saudi Arabia: Cross-Sectional Study by Rahaf Hamdan BinHamdan, Salwa Abdulrahman Alsadhan, Arwa Zohair Gazzaz, AlBandary Hassan AlJameel

“…Additionally, it assessed the associations between engagement with oral health information, self-reported oral health, and the presence and count of these misconceptions. MethodsA cross-sectional survey was conducted over 10 weeks, targeting adults aged 15 years and older in Saudi Arabia. …”
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Unfolding insights about resilience and its coping strategies by medical academics and healthcare professionals at their workplaces: a thematic qualitative analysis by Salman Yousuf Guraya, Jacqueline Maria Dias, Mohamed Ahmed Eladl, Ayah Mohammad Rajai Rustom, Fatima Audi Saleem Alalawi, Majid Hassan Saleh Alhammadi, Yusra Ahmed Mohammed Ahmed, Amna Ali Omran Taryam Al Shamsi, Sarah Juman Bilalaga, Alfred Nicholson, Hani Malik, Shaista Salman Guraya

“…Our research aimed to acquire an in-depth comprehension of how HCPs and MHAs understand, cultivate, and sustain resilience when confronted with workplace challenges and stressors. Methods We reviewed the existing corpus of literature about resilience, stressors, and coping strategies and followed an iterative deliberations process to develop an interview guide. …”
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The Impact of Online Interactive Platform Services on Oral Health Behaviors in Older Adults With Mild Cognitive Impairment: Protocol for a Randomized Controlled Trial by Yin Q, Chai Z, Tao B, Liu P, Luo Y, Zhao Q, Yang B

“…Here we describe the protocol for a study with the following aims: to enhance oral health behaviors through online education tailored to the cognitive load of older adults and to maintain or delay cognitive decline.Patients and Methods: This randomized, parallel, single-blind controlled trial will evaluate the effectiveness of an oral health behavior intervention based on an online interactive platform (e-COM[OH]) in older adults with MCI. …”
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