Serum Ferritin Levels in Pregnancy and Their Association with Gestational Diabetes Mellitus: A Prospective Longitudinal Study by Qin Z, Du Y, Wang Z, Qin X, Wu H, Yu X, Zhao C, Mo L, Huang B

“…However, the changes in SF levels during pregnancy and their relationship with gestational diabetes mellitus (GDM) and blood glucose levels are not well understood.Methods: This prospective longitudinal study included 390 participants (130 GDM cases and 260 controls) during early pregnancy. …”
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Impact of Prior Chronic Kidney Disease and Newly Detected eGFR Impairment at Admission on Outcomes and Prognosis of Hospitalized COVID-19 Patients – A Single-Center Cohort St... by Kania M, Terlecki M, Batko K, Rajzer M, Malecki MT, Krzanowski M

“…This study assessed the effect of prior CKD and RI at admission on in-hospital mortality in COVID-19 patients.Methods: A total of 5191 consecutive patients with COVID-19 admitted between March 6, 2020 and May 31, 2021, to the University Hospital in Krakow were analyzed. …”
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Assessing awareness and treatment knowledge of preventable blindness in rural and urban South African communities by Z Kiva, J E Wolvaardt

“…Rural and urban areas in the Eastern Cape, SA. Methods. A descriptive cross-sectional study was conducted among 309 participants. …”
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Effect of potent nucleos(t)ide analog on alpha fetoprotein changes and occurrence of hepatocellular carcinoma in patients with chronic hepatitis B by Qianqian Ma, Junzhao Ye, Ling Luo, Yanhong Sun, Wei Wang, Shiting Feng, Bing Liao, Bihui Zhong

“…The purpose of this study was to evaluate this issue in those treated with entecavir (ETV) versus tenofovir disoproxil fumarate (TDF). Methods We prospectively enrolled treatment-naive CHB adults who commenced treatment with ETV or TDF. …”
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Age-stratified analysis of the BMI-kidney stone relationship: findings from a national cross-sectional study by Liuliu Zhou, Wei Gu, Yufeng Jiang, Haimin Zhang

“…BackgroundThe association between body mass index (BMI) and kidney stone formation may vary across different age groups and follow nonlinear patterns.MethodsThis study analyzed data from NHANES 2009–2018, including 14,880 participants aged ≥20 years, to evaluate the association between BMI and the risk of kidney stones. …”
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Relationship between social capital and medication adherence among frail and pre-frail older people: a cross-sectional study from China by Zixuan Hong, Ying Guo, Wenwen Cao, Chenglin Cao, Zhi Hu, Jing Yan, Ren Chen, Zhongliang Bai

“…Therefore, this study aims to examine their relationship in older individuals with pre-frailty and frailty, respectively. Methods Information concerning the socio-demographics, frailty, social capital, and medication adherence of 4218 participants was collected through a structured questionnaire during November and December 2020. …”
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Diversity in Adaptive Evolution of Methicillin-Resistant Staphylococcus aureus Clinical Isolates Under Exposure to Continuous Linezolid Stress in vitro by Han T, Jia T, Wang J

“…Thus, this study aims to explore the adaptive evolution characteristics underlying linezolid resistance in MRSA clinical isolates exposed to continuous induction stress of linezolid in vitro.Methods: The in vitro susceptibility of 1032 MRSA clinical isolates to linezolid was detected using commercial VITEK-2 equipment via broth microdilution. …”
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Analisis Efek Augmentasi Dataset dan Fine Tune pada Algoritma Pre-Trained Convolutional Neural Network (CNN) by Theopilus Bayu Sasongko, Haryoko Haryoko, Agit Amrullah

“…Abstract Today deep learning technology is often associated with reliable processes (methods) when we have large amounts of data. In deep learning CNN (Convolutional Neural Network) plays a very important role which is often used to analyze (classify or recognize) visual images. …”
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Adjunctive diagnostic tool for histopathological classification of congenital mesoblastic nephroma based in molecular genetic findings by Hiroshi Hamada, Kenichi Kohashi, Takeshi Iwasaki, Mikiko Hashisako, Yuko Hino, Masahiro Fukuhara, Amane Kamouchi, Naonori Kawakubo, Tatsuro Tajiri, Yoshinao Oda

“…This study aimed to investigate a surrogate marker for the accurate histological classification of CMN. Methods Overall, 11 CMN cases diagnosed at our institute were included in this study. …”
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Stool immunoassay for identification of colorectal cancer and other significant gastrointestinal diseases risk groups by N. S. Sergeeva, Nina V. Marshutina, Ye. V. Zenkina

“…To carry out comparative analysis of diagnostic sensitivity of three immunochemical stool tests as a first step of laboratory algorithm to define high risk groups for colorectal cancer (CRC) and other clinically severe diseases of gastrointestinal tract (GIT). Material and methods. Content of hHb, hHb/ Hp and fTu M2-PK was investigated by solid-phase immunoenzyme tests in stool samples of 447 patients: 157 primary CRC cases, 121 stomach cancer (SC) patients, 64 ulcerative colitis (UC), 20 colonic polyps (CP) patients and 85 healthy donors. …”
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Staphylococcus aureus induces mitophagy via the HDAC11/IL10 pathway to sustain intracellular survival by Yaji Yang, Haotian Zhou, Feilong Li, Yanhao Zhang, Jianye Yang, Yidong Shen, Ning Hu, Quanming Zou, Leilei Qin, Hao Zeng, Wei Huang

“…Although macrophages play a vital role as innate immune cells, the mechanisms by which S. aureus survives within them and suppresses host immune functions remain incompletely understood. Methods This study employed confocal microscopy, flow cytometry, ELISA, and siRNA technology to assess the survival capacity of S. aureus within macrophages and the impact of inflammatory cytokines on its persistence. …”
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The use of emergency medical services for palliative situations in Western Cape Province, South Africa: A retrospective, descriptive analysis of patient records by C Gage, B Spies, K Crombie, L Gwyther, W Stassen

“…To examine EMS use for palliative situations in the Western Cape (WC) Province of SA by describing frequency of intersection, patient characteristics and outcomes. Methods. An observational, descriptive, retrospective patient record review was employed at two hospitals with palliative care services in the WC. …”
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Pastoral livestock farming constraints and adaptation strategies in response to institutional reforms in the Sudano-Sahelian zone of West Africa by Basnewindé Ilboudo, Alhassane Zaré, Alhassane Zaré, Innocent Charles Emmanuel Traoré, Innocent Charles Emmanuel Traoré, Loyapin Bondé, Reginald Tang Guuroh, Reginald Tang Guuroh, Reginald Tang Guuroh, Oumarou Ouédraogo

“…This study aimed to analyze the effects of land tenure and protected area governance reforms on the pastoral production system by identifying concomitantly related constraints and adaptation strategies adopted by local communities.MethodsData was collected through analysis of policy documents, and surveys from 280 key informants and household heads related to the pastoral zone of Yallé using individual interviews and focus group discussions. …”
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Shift from chronic to episodic migraine frequency in a long-term phase 3 study of galcanezumab by Hans-Christoph Diener, Kathleen A. Day, Sarah Lipsius, Sheena K. Aurora, Nada A. Hindiyeh, Holland C. Detke

“…Ability to convert patients from chronic migraine frequency to episodic migraine (EM) frequency is a clinically relevant and desirable outcome when prescribing preventive treatments to patients with CM. Methods Patients aged 18–65 years with an ICHD-3β diagnosis of CM were randomized 2:1:1 to receive monthly injections of placebo (N = 558), galcanezumab 120 mg with a 240-mg loading dose (N = 278), or galcanezumab 240 mg (N = 277) during a 3-month double-blind period of the phase 3 REGAIN trial. …”
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TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis by Xinxing Wang, Mingze Ma, Shuai Shao, Xianwen Xu, Chuan Qin, Ruxin Gao, Zhenhai Zhang

“…This study aims to elucidate the molecular mechanisms by which TWIST1 influences aerobic glycolysis in pancreatic ductal adenocarcinoma (PDAC). Methods The expression levels of TWIST1, MMP9, MT1-MMP, and FDX1 in clinical tissues and cancer cell lines were assessed using quantitative reverse transcription PCR (QRT-PCR). …”
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In vitro and in vivo investigations of selected varieties of Areca catechu L - Phytochemical analysis, antiulcer, and wound healing activity by R. Deveswaran, D.J. Madhu Kumar, V. Madhavan, Soma Chaki, Misbah Khan, Govind R. Kadambi, B.V. Basavaraj, J. Anbu

“…Arecanut, commonly chewed in the Indian subcontinent and Southeast Asia for its purported medicinal benefits, contains arecoline, a pyridine alkaloid known for its pharmacological effects. Methods: Selected varieties of arecanut were subjected to phytochemical analysis, GC-MS, HPTLC analysis, cell line studies using human oral and intestinal cell lines, wound healing, and anti-ulcer activity studies. …”
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A CD36-based prediction model for sepsis-induced myocardial injury by Yun Xie, Hui Lv, Daonan Chen, Peijie Huang, Zhigang Zhou, Ruilan Wang

“…This study aims to develop a predictive model for SIMI using plasma CD36 levels. Methods: A prospective study was conducted from January 1, 2023, to December 1, 2023, involving sepsis patients admitted to the Department of Intensive Care Medicine at Shanghai General Hospital. …”
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Cost-effectiveness analysis for implementation of smoking cessation strategies at primary health care settings in Tamil Nadu. by Vasantha Mahalingam, Ramesh Kumar Santhanakrishnan, Muniyandi Malaisamy, Karthick Chelvanayagam, Kavi Mathiyazhagan, Adhin Bhaskar, Karikalan Nagarajan, Jerard Maria Selvam, Surendran Veeraiah, Kavitha Rajsekar, Kirti Tyagi, Ponnuraja Chinnaiyan

“…<h4>Objectives</h4>To compare the cost-effectiveness of the smoking cessation of proposed strategies (PSs), PS1: enhanced counselling (EC) + nicotine replacement therapy (NRT) + bupropion tablet; PS2: behavioural intervention (BI) + NRT + promotion of bupropion sustained release (SR); PS3: EC + NRT + promotion of bupropion SR with the current strategy (BI +NRT+ Bupropion) in a population of smokers aged ≥15 years attending the PHC in Tamil Nadu.<h4>Methods</h4>In this hypothetical cohort of 100,000 individuals using the decision tree analysis, a cost-effectiveness assessment was conducted for both proposed and existing strategies. …”
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Sacral neuromodulation outcomes in the management of lower urinary tract symptoms in multiple sclerosis patients by Tyler Trump, Po-Ming Chow, Vivian Hua, Omer Anis, Mazen Mansour, Howard B. Goldman

“…The objective of this study is to evaluate sacral neuromodulation (SNM) in the management of LUTS in MS patients METHODS:: Retrospective chart review of patients with a diagnosis of MS undergoing SNM between 2013–2022. …”
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Maximal and Explosive Muscle Strength During Hip Adduction Squeeze and Hip Abduction Press Test Using A Handheld Dynamometer: An Intra- and Inter-tester Reliability Study by Lasse Ishøi, Kristian Thorborg, Laura Krohn, Lars Louis Andersen, Asger Møller Nielsen, MIkkel Bek Clausen

“… # Study design Intra- and interrater reliability study. # Methods Forty-nine healthy subjects were included for intra- (n=20) and inter-tester reliability (n=29). …”
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