Magnesium in pain control - mechanisms of action in perioperative pain, neuropathic pain and migraine by Anna Konarska, Artur Fabijański, Adriana Dukacz, Wojciech Firlej, Joanna Rychlewska-Duda, Justyna Lisiecka, Michał Nowak, Mateusz Janik, Barbara Ufnalska, Anna Machowiak

“…Aim of study This review aims to present the state of knowledge about magnesium’s possible role in pain control and present mechanism of its influence on the nociceptive stimuli reception. Materials and methods Publication research was made using databases PubMed and Google Scholar. …”
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Simultaneous vs Staged Procedures for Bilateral Total Knee Arthroplasty: Reduced Infection, Cost, and Readmission Rates Associated With Simultaneous Procedures by Aaron Singh, BA, Travis M. Kotzur, BS, Kathleen Lundquist, MD, Blaire C. Peterson, BS, William H. Young, MD, Chance C. Moore, MD, Frank Buttacavoli, MD

“…We hypothesize that staged procedures will have superior outcomes. Methods: This retrospective cohort study queried the National Readmissions Database, years 2016-2020, for patients undergoing bilateral TKA via ICD-10 codes. …”
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Dobutamine-induced alterations in internal carotid artery blood flow and cerebral blood flow in healthy adults by Fengxia Yu, Dong Liu, Xia Ma, Yawen Liu, Linkun Cai, Erwei Zhao, Zixu Huang, Zhe Zhang, Tingting Zhang, PengGang Qiao, Wei Zheng, Chunyan Guo, Linxue Qian, Pengling Ren, Zhenchang Wang

“…This study aimed to evaluate the effects of dobutamine infusion on ICA blood flow and CBF, explore their relationship, and identify factors influencing CBF to facilitate timely monitoring in clinical practice. Methods: Forty-eight healthy volunteers underwent physiological assessment, ICA ultrasound, and brain magnetic resonance imaging (MRI) data before and after the administration of dobutamine. …”
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Difference of clinical characteristics in patients with reinfection and primary infection variants of SARS-CoV-2: a retrospective study in China by Chao-Chao Qiu, Xiao-Qing Lin, Qiang Zhang, Ya-Long Chen, Xiao-Qiao Su, Ming-Ying Zhang, Le-Fei Zhu, Zhi-Ruo Lin, Fang Cheng, Shang-Ren Xie, Ji-Chan Shi, Xian-Gao Jiang

“…In this study, we aimed to explore the differences in clinical characteristics between patients with primary infection and those with re-infection of SARS-CoV-2. Methods A retrospective data analysis was conducted involving patients diagnosed with coronavirus disease 2019 between April 1, 2023, and June 20, 2023. …”
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Predictive value of different baseline optical coherence tomography biomarkers for visual acuity changes in neovascular age-related macular degeneration by Hamid Riazi-Esfahani, Hooshang Faghihi, Fatemeh Bazvand, Mohammadreza Mehrabi Bahar, Hassan Khojasteh, Ahmed Husein Ahmed, Shahin Faghihi, Ali Fakhraie, Mohammad Hossein Zamani, Samin Ghasemi, Esmaeil Asadi Khameneh, Elias Khalili Pour

“…Abstract Background To evaluate baseline optical coherence tomography (OCT) biomarkers in treatment-naïve patients with neovascular age-related macular degeneration (nAMD) and their correlation with visual acuity changes following intravitreal aflibercept injections. Methods A retrospective analysis was conducted on treatment-naïve nAMD patients. …”
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Medical care and initial health status of French children returnees from jihadist group operation areas: A cross-sectional study from 2017 to 2020 in one referral French hospital by J. Goutines, L.L. Pham, N. Lucidarme, C. Briand, A. Malka, C. Baker, M. Veyret-Morau, A. Mapelli, A. Klein, T. Baubet, L. De Pontual

“…Since 2017, a national procedure in France has been designed to coordinate their care, including a systematic pediatric medical assessment. Methods: The aim of this cross-sectional study was to assess the prevalence rate of diseases diagnosed at their arrival in France. …”
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Off-the-shelf CAR-NK cells targeting immunogenic cell death marker ERp57 execute robust antitumor activity and have a synergistic effect with ICD inducer oxaliplatin by Jichao Sun, Dinglan Wu, Liuhai Zheng, Huifang Wang, Jihao Zhou, Guangwei Shi, Jingbo Ma, Yuke Jiang, Zhiyu Dong, Jiexuan Li, Yuan-Qiao He, Chengchao Xu, Zhijie Li, Jigang Wang

“…Here, we explore whether immunogenic cell death (ICD) marker ERp57 translocated from endoplasmic reticulum to cell surface after drug treatment could be used as a target for CAR-NK therapy.Methods To target ERp57, a VHH phage display library was used for screening ERp57-targeted nanobodies (Nbs). …”
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Spine surgery and readmission: Risk factors in lumbar corpectomy patients by Julius Gerstmeyer, MD, Anna Gorbacheva, August Avantaggio, Clifford Pierre, MD, Emre Yilmaz, MD, Thomas A. Schildhauer, MD, Amir Abdul-Jabbar, MD, Rod J Oskouian, MD, Jens R Chapman, MD

“…With this study, we aimed to assess the all-cause 90-day readmission rate and identify risk factors for adverse events following a lumbar corpectomy. Methods: Utilizing the 2020 Nationwide Readmissions Database adults (>18 years) were selected by ICD-10 procedure category codes for lumbar corpectomy. …”
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Retrospective comparative survival analysis of ablation plus systemic therapy versus systemic therapy alone for breast cancer liver metastases, stratified by extrahepatic metastase... by Xuxiazi Zou, Hong-Liang Zou, Xuan Luo, Xu-Wei Chen, Wei-Ling Huang, Chao Zhang, Ge Ren, Jin-Hua Huang, Xue Han, Yi-Quan Jiang

“…Purpose: To assess whether ablation plus systemic therapy (AS) improves survival outcomes in patients with BCLM compared to systemic therapy alone. Materials and methods: This retrospective study analyzed patients with BCLM who received either AS or systemic therapy alone. …”
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Incidence, prevalence, and predictors of osteoporotic fracture in adult lung transplant recipients by Elisabeth Ng, Shanal Kumar, Eldho Paul, Daniel Bennett, Luisa Rosi, Louise Fuller, Lauren Chiu, Shoshana Sztal-Mazer, Steven Ivulich, Greg Snell, Leon A. Bach, Kathryn L. Hackman

“…Our institution offers LT recipients protocolized antiresorptive therapy, with zoledronic acid (ZA) used first line. Methods: Adults who underwent LT from January 2012 to December 2018 and survived at least 6 months were retrospectively studied. …”
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Linking obesity-associated genotype to child language development: the role of early-life neurology-related proteomics and brain myelinationResearch in context by Jian Huang, Jinyi Che, Michelle Z.L. Kee, Ai Peng Tan, Evelyn C. Law, Patricia Pelufo Silveira, Irina Pokhvisneva, Sachin Patel, Keith M. Godfrey, Lourdes Mary Daniel, Kok Hian Tan, Yap Seng Chong, Shiao-Yng Chan, Johan G. Eriksson, Dennis Wang, Jonathan Yinhao Huang

“…Summary: Background: The association between childhood obesity and language development may be confounded by socio-environmental factors and attributed to comorbid pathways. Methods: In a longitudinal Singaporean mother-offspring cohort, we leveraged trans-ancestry polygenic predictions of body mass index (BMI) to interrogate the causal effects of early-life BMI on child language development and its effects on molecular and neuroimaging measures. …”
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Antibacterial activity of 1 % Roselle flower nano-emulsion extract (Hibiscus sabdariffa) against peri-implantitis-related bacteria on orthodontic mini-implants: An in vitro study by Ridhofar Akbar Khusnul Abdillah, Theresia Indah Budhy, Ida Bagus Narmada, I Gusti Aju Wahju Ardani, Nastiti Faradilla Ramadhani, Ratri Maya Sitalaksmi, Muhammad Luthfi, Ninik Mas Ulfa, Albertus Putera Nugraha, Tengku Natasha Eleena binti Tengku Ahmad Noor, Alexander Patera Nugraha

“…This study investigates the antibacterial activity of 1 % Roselle flower (H. sabdarifa) nanoemulsion (NE) extract (1 % RNE) toward peri-implantitis bacteria in OMIs. Methods: A phytochemical analysis of 1 % RNE was carried out to examine the active substances possessed in it, such as flavonoids, quinone, saponin, alkaloids, tannins, terpenoids, and steroids. …”
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Herb5GluCon: A novel polyherbal formulation with dual-action inhibiting properties against oxidative stress and glycoside hydrolases – an in silico and in vitro approach by Abbirami Balachandran, Patrick N. Okechukwu, Baskaran Gunasekaran, Jeleń Małgorzata, Beata Morak-Młodawska, Gabriele R.A. Froemming, Sameer Sapra, Charlie A. Lavilla, Jr., Merell P. Billacura, Salini D. Rajendran, Anis Najwa Abdul Rani, Anand Gaurav

“…The study aimed to evaluate the antioxidant and anti-glycoside hydrolase potential of a novel polyherbal formulation (Herb5GluCon) and identify its phytoconstituents. Methods: The in silico molecular docking of the compounds were performed using AutoDock Vina 1.2.0. …”
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Rare and common single nucleotide variants in childhood-onset systemic lupus erythematosus by Elisabet Svenungsson, Iva Gunnarsson, Lars Rönnblom, Ingrid E Lundberg, Andreas Jönsen, Niklas Hagberg, Leonid Padyukov, Marie Wahren-Herlenius, Christopher Sjöwall, Solbritt Rantapää-Dahlqvist, Sule Yavuz, Øyvind Molberg, Dag Leonard, Andrei Alexsson, Maija-Leena Eloranta, Ann-Christine Syvänen, Johanna K Sandling, Gunnel Nordmark, Roland Jonsson, Roald Omdal, Christine Bengtsson, Anders A Bengtsson, Pascal Pucholt, Kerstin Lindblad-Toh, Sergey V Kozyrev, Peter Söderkvist, Johanna Dahlqvist, Jonas Carlsson Almlöf, Daniel Eriksson, Ahmed Sayadi, Åsa Karlsson, Gerli Rosengren Pielberg, Anna Lobell, Eva Murén, Kerstin M Ahlgren, Nils Landegren, Olle Kämpe, Fabiana HG Farias, Argyri Mathioudaki, Jennifer Meadows, Jessika Nordin

“…We therefore investigated the occurrence of rare deleterious variants in patients with childhood-onset SLE (cSLE) and adult-onset SLE (aSLE) and compared the frequency of these variants with their individual SLE polygenic risk score (PRS).Materials and methods Targeted sequencing of 1832 gene regions, including coding regions of 31 genes associated with monogenic SLE, was performed in 958 patients with SLE and 1026 healthy individuals. …”
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Trabecular Bone Remodeling after Lateral Lumbar Interbody Fusion: Indirect Findings for Stress Transmission between Vertebrae after Spinal Fusion Surgery by Naoki Segi, Hiroaki Nakashima, Sadayuki Ito, Jun Ouchida, Ryotaro Oishi, Ippei Yamauchi, Yuichi Miyairi, Yoshinori Morita, Mikito Tsushima, Hiroyuki Tomita, Kazuaki Morishita, Kazuma Ohshima, Tokumi Kanemura, Shiro Imagama

“…This study aimed to investigate whether imaging findings obtained with PLIF are applicable to lateral lumbar interbody fusion (LLIF). Methods: A total of 53 cases who underwent one- or two-level LLIF with polyether ether ketone cage and posterior spinal fixation/fusion (PSF) were retrospectively included in this study. …”
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Systematic review: e-cigarettes vs. conventional cigarettes by Mateusz Janik, Barbara Ufnalska, Joanna Rychlewska-Duda, Justyna Lisiecka, Artur Fabijański, Anna Konarska, Anna Machowiak, Michał Nowak, Wojciech Firlej, Adrianna Dukacz

“…By examining a wide range of studies, we aim to elucidate the potential risks and benefits associated with e-cigarette use and provide a comparison of both electronic and conventional forms of nicotine consumption.   Methods A systematic search was conducted using electronic databases such as PubMed, Scopus, and Web of Science. …”
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Temporal Trends in the Utilization and Survival Outcomes of Lobar, Segmental, and Wedge Resection for Early-Stage NSCLC, 2004 to 2020 by Eden Z. Deng, BS, Xiaofei Wang, PhD, Jianrong Zhang, MD, MPH, Thomas E. Stinchcombe, MD, Chi-Fu (Jeffrey) Yang, MD, Nasser Altorki, MD

“…Introduction: Although lobectomy has long been the standard of surgical treatment for early-stage NSCLC, segmental and wedge resections have become another option often used over the past two decades. Methods: To examine the trends over time in the utilization, quality, and overall survival (OS) differences of lobectomy, segmentectomy, and wedge resection, we performed an observational, population-level study of 76,466 patients with T1 or T2 N0M0 NSCLC tumors 2 cm or less in size in the National Cancer Database, from 2004 to 2020. …”
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Clinical confocal laser endomicroscopy for imaging of autofluorescence signals of human brain tumors and non-tumor brain by Marlen Reichenbach, Sven Richter, Roberta Galli, Matthias Meinhardt, Katrin Kirsche, Achim Temme, Dimitrios Emmanouilidis, Witold Polanski, Insa Prilop, Dietmar Krex, Stephan B. Sobottka, Tareq A. Juratli, Ilker Y. Eyüpoglu, Ortrud Uckermann

“…Therefore, we investigated the potential of a commercial confocal laser scanning endomicroscopy (CLE) system for clinical imaging of brain tumors. Methods A clinical CLE system with fiber probe and 488 nm laser excitation was used to acquire images of tissue autofluorescence. …”
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Chemical profiles of venom glands in queens, foundresses, pre-wintering gynes, and workers in the hornet Vespa velutina nigrithorax by Berville, Laurence, Lucas, Christophe, Haouzi, Mélissa, Khalil, Ali, Gévar, Jérémy, Bagnères, Anne-Geneviève, Darrouzet, Eric

“…Due to its marked invasiveness, this yellow-legged hornet is of great economic and ecological concern, mainly because of the damage it causes to insects in general and bees in particular. Current management methods are sparse and ineffective. Naturally produced by insects, semio-chemicals have been proposed as integrated management tools in this context, either for disruption or mass trapping, as an alternative tool to conventional non-selective traps. …”
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Malnutrition risk, weight loss, and subsequent survival in patients listed for heart transplantation by Tae Kyung Yoo, MD, MS, Satoshi Miyashita, MD, Ariella Stein, MSCIS-HI, Michael Wu, BS, MPH, Lauren Parsly Read-Button, MPH, RD, LDN, Masashi Kawabori, MD, Greg S. Couper, MD, Edward Saltzman, MD, Amanda R. Vest, MBBS, MPH

“…We investigated which malnutrition risk scores – geriatric nutrition risk index (GNRI), prognostic nutritional index (PNI), or controlling nutritional status (CONUT) – have the strongest mortality association for HT candidates, and whether they are prognostic at the time of HT listing or HT operation. Methods: We reviewed adults listed for primary HT at a single center 1987–March 2022, with survival follow-up to November 2022. …”
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