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14641
Real-World Assessment of Weight Change in People with HIV-1 After Initiating Integrase Strand Transfer Inhibitors or Protease Inhibitors
Published 2020-07-01“…**Objective:** To assess differences in weight gain after initiating INSTI- versus protease inhibitor (PI)-based regimens among treatment-naïve PLWH overall, and among a subpopulation of females only. **Methods:** This retrospective, observational cohort study included data from the Optum® deidentified Electronic Health Record (EHR) database. …”
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14642
Laparoscopic suture repair for perforated peptic ulcer disease: a meta-review and trial sequential analysis
Published 2025-02-01“…Meta-epidemiology, as a form of evidence synthesis, allows for the pooling of data and assessment of the diversity present in multiple and overlapping SRs.Aim of the researchThis study aimed to summarize evidence from systematic reviews of randomized controlled trials and reanalyze outcome data on laparoscopic suture repair of perforated peptic ulcers using trial sequential analysis (TSA).Materials and methodsThe Cochrane Library, PubMed, Embase, CINAHL, eLibrary, and ClinicalTrials.gov were searched before 1 June 2024. …”
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14643
The association between pretransplant malignancy and post-transplant survival and cancer recurrence in bilateral lung transplantation: An analysis of 23,291 recipients
Published 2025-02-01“…Background: Given the increasing need for lung transplants among older patients with a history of cancer, this study analyzed database registry to assess outcomes for bilateral lung transplant (BLT) recipients with pre-transplant malignancy (TM). Methods: This study evaluated the United Network for Organ Sharing registry for adult BLT performed between 2005 and 2023. …”
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14644
Efficacy of Physiologically Active nutrients in the Treatment of Asthenic Disorders in Patients with Chronic Diffuse Liver Diseases
Published 2019-09-01“…To study the efficacy of the “Hepato Smart” nutraceutical product for the treatment of asthenic syndrome in outpatients suffering from chronic diffuse liver diseases with compensated function and functional disorders of the gallbladder over the period after exacerbation.Materials and methods. The study included 50 patients, with 41 of them having completed the program. …”
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14645
Determinants of minimum meal frequency among children in Kumbungu District of Ghana: a cross-sectional study
Published 2025-02-01“…This study therefore examined minimum meal frequency and its determinants among children aged 6 to 23 months in Kumbungu District, Ghana. Methods An analytical cross-sectional study design was used and involved 395 mother-child pairs selected through systematic random sampling. …”
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14646
Major adverse cardiovascular events among Black and White Veterans receiving androgen deprivation therapy for prostate cancer: a retrospective cohort study
Published 2025-02-01“…Secondly, we sought to determine if Black men receiving RT + ADT developed MACE at a higher rate than White men. Methods This retrospective cohort study examined time to diagnosis of MACE among Veterans with PC. …”
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14647
Carbapenem resistance in gram-negative pathogens in an Iranian hospital: high prevalence of OXA-type carbapenemase genes
Published 2025-01-01“…Purpose This study aimed to investigate the prevalence of carbapenem resistance in gram-negative bacteria isolated from patients at the Children's Medical Center Hospital, Tehran, Iran, to understand the molecular mechanisms underlying this resistance. Methods During the period spanning from June 2019 to June 2020, 777 gram-negative bacterial strains were isolated. …”
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14648
Patient–specific hemodynamic modeling to optimize LVAD speed and right heart health
Published 2025-02-01“…A virtual hemodynamic model (VHM) that can be tailored to each patient may provide useful guidance and reduce repeated studies. Methods: We conducted a retrospective analysis on 16 patients implanted with HeartMate 3 (HM3) who underwent RHC speed titration study as an outpatient. …”
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14649
Efficacy and safety of pharmacotherapy for cancer cachexia: A systematic review and network meta‐analysis
Published 2024-09-01“…Evidence‐based approaches are urgently needed to optimize treatment. Methods A systematic review and network meta‐analysis were conducted to assess the effectiveness and safety of different pharmacotherapies for cancer cachexia. …”
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14650
Spatial and seasonal distribution of selected nitrogen cycle genes in deep waters of the Baltic Proper
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14651
Study of long-acting vs daily growth hormone: peak levels, AUC, action duration, and IGF-1
Published 2024-12-01“…Objectives: This review assesses the impact of LAGH therapy on serum levels of GH and insulin-like growth factor-1 (IGF-1) and evaluates the potential metabolic and safety risks compared to the natural pulsatile secretion of GH and daily GH injections in normal children. Methods: A comprehensive literature search identified studies examining the effects of LAGH therapy on serum GH and IGF-1 levels. …”
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14652
Risk Factors For Progression From Biochemical Leak to Clinically Relevant Postoperative Pancreatic Fistula After Pancreaticoduodenectomy. The Key of the Lock: Prognostic Nutritiona...
Published 2025-02-01“…In the present study, we aimed to determine the risk factors that increase the progression from biochemical leak (BL) to clinically relevant postoperative pancreatic fistula (CR-POPF) after PD. Materials and Methods: We retrospectively analyzed the data of 152 patients who underwent PD. …”
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14653
The effect of a community-based health behaviour intervention on healthcare services use among people with type 2 diabetes in Nepal
Published 2025-03-01“…Therefore, this study aimed to assess the effect of intervention in improving the visits to health facilities and specialists and reducing emergency department visits and hospital admissions among people with T2DM in Nepal. Methods: A cluster-randomised controlled trial was conducted in the Kavrepalanchowk and Nuwakot districts of Nepal, enrolling 481 people with clinically diagnosed type 2 diabetes, aged 30–70 years. …”
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14654
Machine Learning in the Management of Patients Undergoing Catheter Ablation for Atrial Fibrillation: Scoping Review
Published 2025-02-01“…ObjectiveThis scoping review aimed to evaluate the current scientific evidence on the application of ML for managing patients undergoing AFCA, compare the performance of various models across specific clinical tasks within AFCA, and summarize the strengths and limitations of ML in this field. MethodsAdhering to the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) guidelines, relevant studies published up to October 7, 2023, were searched from PubMed, Web of Science, Embase, the Cochrane Library, and ScienceDirect. …”
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14655
Primary and tertiary management of ocular surface lesions in HIV-infected patients in Ehlanzeni, Mpumalanga Province
Published 2024-06-01“…To assess the knowledge, attitude and current practice of HCWs working in HIV clinics regarding ocular surface lesions and to evaluate the management of patients with ocular surface lesions at a tertiary hospital. Methods. A cross-sectional study design was used (November 2020 - May 2021), for which 149 HCWs were invited to assessments about their knowledge, attitudes and practices regarding ocular surface lesions. …”
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14656
Multicomponent intervention for schoolchildren with asthma: Pilot cluster randomized controlled trial
Published 2025-05-01“…Objective: We assessed preliminary effectiveness of a pilot multicomponent asthma intervention that includes classroom-based PA, asthma education to increase knowledge and reduce stigma, and care coordination to facilitate guideline-based care, on PA and symptom-free days (SFD) in urban, historically marginalized children with asthma. Methods: Children aged 7-10 years with asthma and their caregivers were recruited from 4 Bronx, NY, schools. …”
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14657
Effect of daily alcohol consumption and age over 40 years on COVID-19 vaccination antibody titers in the Delta era among hospital workers in northern Okinawa, Japan: A retrospectiv...
Published 2025-02-01“…The aim of this study was to investigate the impact of lifestyle factors on COVID-19 vaccination antibody titers. Methods: Antibody titers of 354 hospital workers who received two COVID-19 vaccination doses were measured five times for more than six months. …”
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14658
Analysis of factors associated with intercostal neuralgia after osteoporotic thoracic spine fracture and construction of a prediction model
Published 2025-02-01“…Abstract Objective This study aims to investigate the associated factors of intercostal neuralgia in patients with osteoporotic vertebral compression fractures (OVCF) of the thoracic spine and to develop a predictive model to assess the likelihood of patients developing intercostal neuralgia following thoracic vertebral fractures. Methods The retrospective study involved 518 patients with thoracic OVCF treated at our hospital, among whom those with and without intercostal neuralgia were matched at a 1:1 ratio.Relevant basic clinical data and imaging parameters of the patients were recorded, t-test was used for continuous variables and chi-square test for categorical variables to determine the factors associated with intercostal neuralgia. …”
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14659
Neonatal BCG vaccination and child survival in TB-exposed and TB-unexposed children: a prospective cohort study
Published 2020-02-01“…Children residing in the same house as a TB case were classified as TB-exposed from 3 months prior to case registration to the end of follow-up.Methods Using Cox-proportional hazards models with age as underlying time scale, we compared mortality of children with and without neonatal BCG between October 2003 and September 2017.Main outcome measure HR for neonatal BCG compared with no neonatal BCG by TB-exposure status.Results Among the 39 421 children who entered the analyses, 3022 (8%) had observation time as TB-exposed. …”
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14660
Assessment of stress hyperglycemia ratio to predict all-cause mortality in patients with critical cerebrovascular disease: a retrospective cohort study from the MIMIC-IV database
Published 2025-02-01“…This study aims to investigate the predictive ability of SHR for in-hospital mortality in critically ill cerebrovascular disease patients and to assess its potential to enhance existing predictive models. Methods We extracted data from the Medical Information Mart for Intensive Care (MIMIC-IV) database for patients diagnosed with cerebrovascular disease and used Cox regression to assess the association between SHR and mortality. …”
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