Long term cost-effectiveness analysis of IDegLira in the treatment of type 2 diabetes patients compared to GLP-1RA added to basal insulin after IDegLira entered the national reimbu... by Dunming Xiao, Junling Weng, Lei Zhang, Chang Xing, Yan Wei, Yingyao Chen

“…This study aimed to evaluate the long-term cost-effectiveness of IDegLira versus GLP-1RA added to basal insulin regimen (combined regimen) for patients with type 2 diabetes in China.<h4>Methods</h4>Based on the perspective of the health system, the study adopts the Swedish Institute for Health Economics diabetes cohort model. …”
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WNT3A promotes the cementogenic differentiation of dental pulp stem cells through the FOXO1 signaling pathway by Dongmei Cheng, Yang Bao, Xue Wang, Haidong Xiang, Tianyuan Guo, Yong Du, Zhiyong Zhang, Han Guo

“…The molecular mechanisms underlying cementogenic differentiation of DPSCs remain unclear. Methods DPSC data set GSE138179 was retrieved from gene expression omnibus (GEO) database. …”
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Opioid-free versus opioid-based anesthesia in laparoscopic sleeve gastrectomy: a single-center, randomized, controlled trial by Hanane Barakat, Linda Gholmieh, Jessy Abou Nader, Vanda Yazbeck Karam, Obey Albaini, Mohamad El Helou, Rony Al Nawwar

“…This study aims to investigate the efficacy of opioid-free anesthesia (OFA) compared to traditional opioid-based anesthesia (OBA) in patients undergoing laparoscopic sleeve gastrectomy. Methods This single-center randomized controlled trial included eighty-three patients undergoing laparoscopic sleeve gastrectomy in a tertiary hospital. …”
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Complete metabolic response as early predictor of long-term efficacy after adoptive T cell therapy using tumor-infiltrating lymphocytes by Rikke Andersen, Troels Holz Borch, Eva Ellebaek, Inge Marie Svane, Helle Westergren Hendel, Kasper Madsen

“…In this study the predictive value of early metabolic response after TIL therapy is explored.Materials and methods: 60 patients treated with TIL therapy in 4 different clinical trials and with available [18F]2-fluoro-2-deoxy-d-glucose positron emission tomography-CT (FDG-PET/CT) scans at baseline and at least one follow-up scan 6–8 weeks and/or 12–16 weeks post-TIL infusion were included.Results: Obtaining complete metabolic response (CMR) was associated with significantly superior median overall survival (mOS) compared with not obtaining CMR (p&lt;0.0001). …”
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Higher gut Bacteroidetes and Actinobacteria population in early pregnancy is associated with lower risk of gestational diabetes in the second trimester by Seyedeh Neda Mousavi, Navid Momeni, Hossein Chiti, Howra Mahmoodnasab, Mohammad Ahmadi, Siamak Heidarzadeh

“…Abstract Background Despite the association between the gut dysbiosis and metabolic disorders, the main bacterial phylum in the first trimester of pregnancy that predisposes mothers to gestational diabetes mellitus (GDM) in the second trimester is not clear around the world. Materials and methods Three-hundred healthy women aged 18–40 years who were in the first trimester were participated in this cohort study and followed to the screening time for GDM diagnosis (in 24–28 weeks of pregnancy). …”
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Functional analysis of heterozygous variants in the SALL1 gene in 2 children with Townes-Brocks syndrome with FSGS by Rong Liang, Bixia Zheng, Chunli Wang, Sanlong Zhao, Wei Zhou, Ying Chen, Ruochen Che

“…Abstract Background To investigate the functional characteristics of heterozygous variants in the SALL1 gene in two children with Townes-Brocks syndrome (TBS), as well as the underlying mechanisms leading to chronic kidney disease. Methods We retrospectively analyzed the clinical manifestations, laboratory findings, and genetic backgrounds of two TBS patients admitted to our hospital presenting with chronic kidney disease stage 2 and focal segmental glomerulosclerosis (FSGS). …”
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Percutaneous Closure Device Controlled INCRAFT Stentgraft Implantation Registry (PUCCINI) by T. Engelen, R. Hoogervorst, K. DeLoose, L. C. van Dijk, R. S. van Eps, R. B. van Tongeren, H. T. Veger, L. Maene, W. Stomp, O. R. Wikkeling, S. J. C. Klink, W. van den Eynde, J. J. Wever, H. van Overhagen

“…The feasibility and safety of the use of the INCRAFT AAA Stentgraft System and the ProGlide vascular closure system was assessed. Methods The PUCCINI trial prospectively enrolled patients undergoing elective repair of infrarenal AAA at 3 centres in the Netherlands and 3 centres in Belgium. …”
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Current and future burden of breast cancer in Asia: A GLOBOCAN data analysis for 2022 and 2050 by Mengxia Fu, Zhiming Peng, Min Wu, Dapeng Lv, Yanping Li, Shuzhen Lyu

“…This study seeks to analyze the burden of breast cancer in Asia based on the most recent GLOBOCAN 2022 estimates. Methods: Data were obtained from GLOBOCAN 2022. Age-standardized rates for incidence and mortality per 100,000 person-years were calculated using direct age standardization with the Segi-Doll World standard population. …”
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Indicators Of Morbidity And Mortality From Diseases of the Digestive System in the Krasnodar Krai and the Quality of Medical Care for Gastroenterological Patients by N. V. Korochanskaya, V. M. Durleshter, O. V. Kovalevskaya, S. N. Serikova, K. I. Popandopulo

“…To analyse the dynamics of morbidity and mortality from diseases of the digestive system, as well as the quality of medical care for gastroenterological patients in the Krasnodar Krai.Materials and methods. The analysis was carried out according to C 51 “Distribution of deaths by gender, age groups and causes of death” form of the Territorial Authority of the Federal State Statistics Service for the Krasnodar Krai for the period from 2006 to 2018, as well as on the basis of the “Demography” block database of the Parus software of the healthcare management system of the Krasnodar Krai for 6 months of 2019. 1341 medical records of patients receiving outpatient medical care and the medical records of people who had died from digestive diseases in 2017-2019 were reviewed.Results. …”
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Examining Sex Differences in Visual Reliance During Postural Control in Intercollegiate Athletes by Nicolette Ingel, Victoria Vice, Courtney Dommer, Jennifer Csonka, Tara Moore, Ariel Zaleski, Carolyn Killelea, Mallory Faherty, Jody Feld, Timothy Sell

“… # Study Design Cross-sectional Study # Methods Static postural stability was assessed during a single session for football, soccer, basketball, and volleyball intercollegiate athletes (males, n=135, females, n=51) under eyes open (EO) and eyes closed (EC) conditions via performance of single limb stance on a force plate. …”
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Impact of fetal sex on neonatal outcomes in women with gestational diabetes mellitus: a systematic review and meta-analysis by Mahsa Maghalian, Zohreh Alizadeh-Dibazari, Mojgan Mirghafourvand

“…Therefore, the aim of our study was to investigate the impact of fetal sex on neonatal outcomes in mothers with GDM. Methods We conducted a systematic search of six database) PubMed, Cochrane Library, Scopus, Web of Science, SID (Persian database), and Embase (up to January 1, 2025. …”
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Comparing the Effectiveness of Intra-articular Injection with Autologous Platelet-rich Plasma vs Hyaluronic Acid vs Platelet-derived Growth Factors in Early Osteoarthritis of Knee... by Vidya S Konana, Harish S Yallapura, Sriharsha Bettaswamy, Srinivas P Sivaram, Darshan G Thimmegowda

“…Aims: To compare the effectiveness between intra-articular injection (IAI) of autologous platelet-rich plasma (PRP) vs hyaluronic acid (HA) vs activated PRP in primary osteoarthritis (OA) of the knee grades 1 and 2, in terms of pre- and postinjection functional outcome by the Western Ontario and McMaster Universities Arthritis Index (WOMAC) scale, and pre- and postinjection pain by visual analog scale (VAS). Materials and methods: The patients were divided into three groups based on the treatment they received. …”
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A new scheme for boosting in situ Fenton-like reaction in plant pathogenic tissues for selective structural degradation of capsid proteins by Jun Ma, Ming Chen, Yujie Wang, Jiaying Li, Jian Tang, Shengjun Wu, Chi He, J. Paul Chen

“…We designed a new Fenton-like reaction inducer, tCuinter-bCDs, which utilizes an internal doping strategy that reduces copper content by 89.89% compared to conventional doping methods, while still achieving a high coexistence of multivalent copper ions. …”
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Kombinasi Seleksi Fitur Berbasis Filter dan Wrapper Menggunakan Naive Bayes pada Klasifikasi Penyakit Jantung by Siti Roziana Azizah, Rudy Herteno, Andi Farmadi, Dwi Kartini, Irwan Budiman

“…In the classification of medical datasets, Naive Bayes is one of the best methods used. The purpose of this study is to determine the comparison of the accuracy results of Naive Bayes using several feature selections, namely Forward Selection, Backward Elimination, a combination of union of Forwad Selection and Backward Elimination feature selection results, Information Gain, Gain Ratio, and a combination of union of Information Gain feature selection results with Gain Ratio. …”
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Late initiation of antenatal care visit amid implementation of new antenatal care model in Sub-Saharan African countries: A multilevel analysis of multination population survey dat... by Kusse Urmale Mare, Gashaye Gobena Andargie, Abdulkerim Hassen Moloro, Ahmed Adem Mohammed, Osman Ahmed Mohammed, Beriso Furo Wengoro, Begetayinoral Kussia Lahole, Tesfahun Simon Hadaro, Simeon Meskele Leyto, Petros Orkaido Mamo, Abdulhakim Hora Hedato, Beminate Lemma Seifu, Temesgen Gebeyehu Wondmeneh, Oumer Abdulkadir Ebrahim, Kebede Gemeda Sabo

“…Thus, we aimed to determine the pooled prevalence of late antenatal care visit and its determinants among women in Sub-Saharan Africa (SSA) using national surveys conducted after the implementation of new guidelines.<h4>Methods</h4>We analyzed data from the recent demographic and health survey (DHS) conducted in 16 SSA between 2018 and 2022 using a weighted sample of 101,983 women who had antenatal care follow-up during their index pregnancy. …”
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Genome-based analysis of the genetic pattern of black sheep in Qira sheep by Wen Zhou, Xiaopeng Li, Xuechen Zhang, Lijun Zhu, Yuwei Peng, Cheng-long Zhang, Zhipeng Han, Ruizhi Yang, Xinyu Bai, Quanfeng Wang, Yuejun Zhao, Shudong Liu

“…In order to explore the candidate genes related to black wool formation in Qira sheep. Methods We selected 123 adult healthy ewes with different coat colors in Qira sheep groups (black (B), brown (Y) and grey (G)) and extracted DNA from their venous blood to obtain Illumina Ovine SNP 50K chip data. …”
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Deciphering the multifaceted mechanism of Shuang Huang Lian in treating upper respiratory tract infections: A metabolomics-based network pharmacology approach by Gang Xu, Akshay Suresh Patil, Ruhan Wei, Dan Liu, Aimin Zhou, Yan Xu

“…However, its precise mechanisms of action against URTIs remain unclear, necessitating further exploration. Methods: This study investigates the molecular mechanisms and identifies the key active components and pivotal protein targets of SHL in URTI treatment using a network pharmacology approach. …”
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Activin levels correlate with lymphocytic infiltration in epithelial ovarian cancer by Elizabeth T. Evans, Emily F. Page, Alex Seok Choi, Zainab Shonibare, Andrea G. Kahn, Rebecca C. Arend, Karthikeyan Mythreye

“…We sought to explore differences in activin (INHBA/ Inhibin‐βA and INHBB/ Inhibin‐βB) between malignant and ovarian tissues at the RNA and protein level and assess the relationship between activin and immune cells in EOC. Methods Publicly available RNA sequencing data were accessed from GEO (#GSE143897) with normalization and quantification performed via DESeq2. …”
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Global magnitude and temporal trends of stroke attributable to lead exposure from 1990 to 2021 by Ying Wang, Ran Liu, Wenxia Li, PengNan Bao, JinWei Zhang, Wei Yue

“…This study evaluates the temporal and spatial trends in the disease burden of stroke and its three subtypes attributable to lead exposure in 204 countries and territories from 1990 to 2021. Methods: Data from Global Burden of Disease Study (GBD) 2021 were used to estimate annual deaths, disability-adjusted life years (DALYs), age-standardized mortality rate (ASMR), and age-standardized DALY rate (ASDR) of stroke attributable to lead exposure. …”
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Expression of CSTF2 in oral squamous cell carcinoma and its relationship with immune infiltration and poor prognosis by Zumulaiti Aierken, Muertiza Muhetaer, Zhang Lei, Ainiwaerjiang Abudourousuli, Ainiwaerjiang Abudourousuli

“…However, its specific association with patient prognosis and immune cell infiltration in OSCC remains insufficiently understood.MethodsTo assess the expression levels and prognostic implications of CSTF2 in OSCC, comprehensive data were acquired from The Cancer Genome Atlas (TCGA) and subsequently normalized. …”
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